Page last updated: 2024-10-20

pyruvic acid and Leukemia, Myeloid, Acute

pyruvic acid has been researched along with Leukemia, Myeloid, Acute in 5 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
" Tigecycline is relatively unstable after reconstitution, and this instability may limit the use of the drug in ambulatory infusions for the treatment of infection and may prevent the development of optimal dosing schedules for the treatment of AML."1.40A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. ( Goard, CA; Gronda, M; Hurren, R; Jhas, B; Jitkova, Y; Schimmer, AD; Wang, X, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Jiang, Y1
Wang, T1
Sheng, D1
Han, C1
Xu, T1
Zhang, P1
You, W1
Fan, W1
Zhang, Z1
Jin, T1
Duan, X1
Yuan, X1
Liu, X1
Zhang, K1
Ruan, K1
Shi, J1
Guo, J1
Cheng, A1
Yang, Z1
Khan, DH1
Mullokandov, M1
Wu, Y1
Voisin, V1
Gronda, M2
Hurren, R2
Wang, X2
MacLean, N1
Jeyaraju, DV1
Jitkova, Y2
Xu, GW1
Laister, R1
Seneviratne, A1
Blatman, ZM1
Ketela, T1
Bader, GD1
Marhon, SA1
De Carvalho, DD1
Minden, MD1
Gross, A1
Schimmer, AD2
Zacharias, NM1
Baran, N1
Shanmugavelandy, SS1
Lee, J1
Lujan, JV1
Dutta, P1
Millward, SW1
Cai, T1
Wood, CG1
Piwnica-Worms, D1
Konopleva, M1
Bhattacharya, PK1
Goard, CA1
Jhas, B1
Malvoisin, E1
Wild, F1
Zwingelstein, G1

Other Studies

5 other studies available for pyruvic acid and Leukemia, Myeloid, Acute

ArticleYear
Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:11

    Topics: Cell Division; Cell Line, Tumor; Glycolysis; Humans; Leukemia, Myeloid, Acute; Phosphorylation; Pyru

2022
Mitochondrial carrier homolog 2 is necessary for AML survival.
    Blood, 2020, 07-02, Volume: 136, Issue:1

    Topics: Acetylation; Animals; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; CRISPR-Cas Systems; Feta

2020
Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-Time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia.
    Molecular cancer therapeutics, 2019, Volume: 18, Issue:11

    Topics: Animals; Benzeneacetamides; Cell Line, Tumor; Cell Proliferation; Cell Survival; HL-60 Cells; Humans

2019
A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Ascorbic Acid; Cell Line, Tumor; Cell Survival; Chromatography, High

2014
Relationship between membrane sterol composition and responsiveness to 12-O-tetradecanoylphorbol 13-acetate in HL-60 human promyelocytic leukaemia cell lines.
    The Biochemical journal, 1988, Mar-01, Volume: 250, Issue:2

    Topics: Acetates; Carbon Radioisotopes; Cell Line; Cholesterol; Humans; Lanosterol; Leucine; Leukemia, Myelo

1988