pyruvic acid has been researched along with Kidney Neoplasms in 10 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Kidney Neoplasms: Tumors or cancers of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Determining the aggressiveness of renal cell carcinoma (RCC) noninvasively is a critical part of the diagnostic workup for treating this disease that kills more than 15,000 people annually in the USA." | 1.62 | Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models. ( Ahamed, F; Kurhanewicz, J; Larson, P; Sriram, R; Van Criekinge, M; Wang, ZJ, 2021) |
| "Of the 8 patients, 3 had high-grade clear cell renal cell carcinoma (ccRCC), 3 had low-grade ccRCC, and 2 had chromophobe RCC." | 1.62 | Metabolic imaging with hyperpolarized ( Gordon, JW; Larson, PEZ; Meng, MV; Slater, JB; Stohr, BA; Tang, S; Vigneron, DB; Wang, ZJ, 2021) |
| "Glycolysis and antioxidant pathways in kidney cancer are elevated, with frequent mutation of the VHL gene." | 1.46 | Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors. ( Ando, A; Araki, H; Hara, T; Honda, K; Kitazawa, S; Morimoto, M; Nishizawa, S; Nutahara, K; Okegawa, T; Satomi, Y; Tamura, T, 2017) |
| "In a renal cell carcinoma cell (RCC) line, bidirectional exchange was observed." | 1.42 | Dynamic UltraFast 2D EXchange SpectroscopY (UF-EXSY) of hyperpolarized substrates. ( Koelsch, B; Kurhanewicz, J; Larson, P; Leon Swisher, C; Santos, RD; Sriram, R; Sukumar, S; Vigneron, D; Wang, ZJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ricci, L | 1 |
| Stanley, FU | 1 |
| Eberhart, T | 1 |
| Mainini, F | 1 |
| Sumpton, D | 1 |
| Cardaci, S | 2 |
| Ahamed, F | 1 |
| Van Criekinge, M | 1 |
| Wang, ZJ | 3 |
| Kurhanewicz, J | 2 |
| Larson, P | 2 |
| Sriram, R | 2 |
| Tang, S | 1 |
| Meng, MV | 1 |
| Slater, JB | 1 |
| Gordon, JW | 1 |
| Vigneron, DB | 1 |
| Stohr, BA | 1 |
| Larson, PEZ | 1 |
| Okegawa, T | 1 |
| Morimoto, M | 1 |
| Nishizawa, S | 1 |
| Kitazawa, S | 1 |
| Honda, K | 1 |
| Araki, H | 1 |
| Tamura, T | 1 |
| Ando, A | 1 |
| Satomi, Y | 1 |
| Nutahara, K | 1 |
| Hara, T | 1 |
| Koh, E | 1 |
| Kim, YK | 1 |
| Shin, D | 1 |
| Kim, KS | 1 |
| Dong, Y | 1 |
| Eskandari, R | 1 |
| Ray, C | 1 |
| Granlund, KL | 1 |
| Santos-Cunha, LD | 1 |
| Miloushev, VZ | 1 |
| Tee, SS | 1 |
| Jeong, S | 1 |
| Aras, O | 1 |
| Chen, YB | 1 |
| Cheng, EH | 1 |
| Hsieh, JJ | 1 |
| Keshari, KR | 1 |
| Leon Swisher, C | 1 |
| Koelsch, B | 1 |
| Sukumar, S | 1 |
| Santos, RD | 1 |
| Vigneron, D | 1 |
| Zheng, L | 1 |
| MacKay, G | 1 |
| van den Broek, NJ | 1 |
| MacKenzie, ED | 1 |
| Nixon, C | 1 |
| Stevenson, D | 1 |
| Tumanov, S | 1 |
| Bulusu, V | 1 |
| Kamphorst, JJ | 1 |
| Vazquez, A | 1 |
| Fleming, S | 1 |
| Schiavi, F | 1 |
| Kalna, G | 1 |
| Blyth, K | 1 |
| Strathdee, D | 1 |
| Gottlieb, E | 1 |
| Semenza, GL | 1 |
| Eker, P | 1 |
| Eker, R | 1 |
| Johannessen, JV | 1 |
1 review available for pyruvic acid and Kidney Neoplasms
| Article | Year |
|---|---|
HIF-1 mediates the Warburg effect in clear cell renal carcinoma.
Topics: Animals; Carcinoma, Renal Cell; Glucose; Glycolysis; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Ind | 2007 |
9 other studies available for pyruvic acid and Kidney Neoplasms
| Article | Year |
|---|---|
Pyruvate transamination and NAD biosynthesis enable proliferation of succinate dehydrogenase-deficient cells by supporting aerobic glycolysis.
Topics: Animals; Carcinoma, Renal Cell; Cell Proliferation; Glycolysis; Kidney Neoplasms; Mice; NAD; Pyruvic | 2023 |
Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models.
Topics: Alginates; Animals; Bioreactors; Carcinoma, Renal Cell; Cell Line, Tumor; Humans; Kidney Neoplasms; | 2021 |
Metabolic imaging with hyperpolarized
Topics: Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Magnetic Resonance Imaging; Pyruvic Acid; Reproduci | 2021 |
Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors.
Topics: Acrylates; Animals; Antineoplastic Agents; Cells, Cultured; Female; Glycolysis; Humans; Kidney Neopl | 2017 |
MPC1 is essential for PGC-1α-induced mitochondrial respiration and biogenesis.
Topics: Carcinoma, Renal Cell; Energy Metabolism; Gene Expression Regulation, Neoplastic; Humans; Kidney Neo | 2018 |
Hyperpolarized MRI Visualizes Warburg Effects and Predicts Treatment Response to mTOR Inhibitors in Patient-Derived ccRCC Xenograft Models.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Renal Cell; Humans; Image Processing, Computer-Assi | 2019 |
Dynamic UltraFast 2D EXchange SpectroscopY (UF-EXSY) of hyperpolarized substrates.
Topics: Alanine; Carcinoma, Renal Cell; Cell Line, Tumor; Enzyme Inhibitors; Enzymes; Humans; Kidney Neoplas | 2015 |
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Topics: Animals; Aspartic Acid; Carboxylic Acids; Carcinoma, Renal Cell; Cell Line, Transformed; Cell Prolif | 2015 |
Establishment and characterization of a new cell line from a hereditary renal rat tumor.
Topics: Animals; Blood; Cell Division; Cell Line; Cell Nucleus; Clone Cells; Culture Media; Cytoplasm; Endop | 1983 |