pyruvic acid has been researched along with Intraocular Pressure in 6 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of these, 42 patients with treated open-angle glaucoma and moderate visual field loss in at least 1 eye were selected for inclusion and randomized." | 1.72 | Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial. ( Blumberg, DM; Cioffi, GA; De Moraes, CG; John, SWM; Liebmann, JM; Williams, PA, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| De Moraes, CG | 2 |
| John, SWM | 2 |
| Williams, PA | 2 |
| Blumberg, DM | 1 |
| Cioffi, GA | 1 |
| Liebmann, JM | 2 |
| Quah Qin Xian, N | 1 |
| Wong, FYK | 1 |
| Harder, JM | 1 |
| Guymer, C | 1 |
| Wood, JPM | 1 |
| Daskalaki, E | 1 |
| Chidlow, G | 1 |
| Zhang, C | 1 |
| Balasubramanian, R | 1 |
| Cardozo, BH | 1 |
| Foxworth, NE | 1 |
| Deering, KE | 1 |
| Ouellette, TB | 1 |
| Montgomery, C | 1 |
| Wheelock, CE | 1 |
| Casson, RJ | 1 |
| Pattarini, JM | 1 |
| Blue, RS | 1 |
| Aikins, LT | 1 |
| Law, J | 1 |
| Walshe, AD | 1 |
| Garbino, A | 1 |
| Turney, MW | 1 |
| Clark, JB | 1 |
| Yoo, MH | 1 |
| Lee, JY | 1 |
| Lee, SE | 1 |
| Koh, JY | 1 |
| Yoon, YH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study[NCT05695027] | Phase 2/Phase 3 | 188 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| Nutritional Supplements and Performance During Visual Field Testing[NCT03797469] | 32 participants (Actual) | Interventional | 2019-04-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvic acid and Intraocular Pressure
| Article | Year |
|---|---|
Flat spin and negative Gz in high-altitude free fall: pathophysiology, prevention, and treatment.
Topics: Altitude; Arrhythmias, Cardiac; Blood Glucose; Brain Edema; Cerebrovascular Circulation; Confusion; | 2013 |
5 other studies available for pyruvic acid and Intraocular Pressure
| Article | Year |
|---|---|
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Combined Use of Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma-Reply.
Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Niacinamide; Pyruvic Acid | 2022 |
Combined Use of Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma.
Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Niacinamide; Pyruvic Acid | 2022 |
Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin.
Topics: Animals; Disease Models, Animal; Glaucoma; Glucose; Intraocular Pressure; Mice, Inbred C57BL; Mice, | 2020 |
Protection by pyruvate of rat retinal cells against zinc toxicity in vitro, and pressure-induced ischemia in vivo.
Topics: Adenosine Triphosphate; Animals; Cell Culture Techniques; Cell Survival; Chlorides; Cytoprotection; | 2004 |