pyruvic acid has been researched along with Intracranial Aneurysm in 17 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bedside intracerebral microdialysis monitoring of patients with subarachnoid hemorrhage and signs of delayed ischemia revealed dramatic changes in extracellular concentrations of glucose, lactate, and glycerol that could be directly correlated to the clinical status of the patients." | 3.70 | Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration. ( Brandt, L; Nilsson, OG; Säveland, H; Ungerstedt, U, 1999) |
| "The majority of patients with poor-grade subarachnoid hemorrhage (SAH), that is, World Federation of Neurosurgical Societies (WFNS) Grades IV and V, have high morbidity and mortality rates." | 2.71 | Poor-grade aneurysmal subarachnoid hemorrhage: relationship of cerebral metabolism to outcome. ( Haux, D; Küchler, I; Lanksch, WR; Sarrafzadeh, A; Unterberg, AW, 2004) |
| "In severe aneurysmal subarachnoid hemorrhage (aSAH), pathological changes in cerebral energy metabolism can be detected either by local measurements using cerebral microdialysis (cMD) together with brain tissue oxygen probe or by global measurements of arterio-jugular difference performed with retrograde jugular vein catheter." | 1.42 | Biochemical neuromonitoring of poor-grade aneurysmal subarachnoid hemorrhage: comparative analysis of metabolic events detected by cerebral microdialysis and by retrograde jugular vein catheterization. ( Barcelos, GK; Dailler, F; Marinesco, S; Perret-Liaudet, A; Renaud, B; Tholance, Y, 2015) |
| "Aneurysmal subarachnoid hemorrhage (SAH) is frequently associated with delayed neurological deterioration (DND)." | 1.40 | Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage. ( Jacobsen, A; Nielsen, TH; Nilsson, O; Nordström, CH; Schalén, W, 2014) |
| "In a 36-year-old man, an anterior communicating artery aneurysm caused an SAH (Hunt and Hess Grade IV, Fisher Grade III)." | 1.32 | Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case report. ( Behr, R; Hoelper, BM; Hofmann, E; Soldner, F; Sporleder, R, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Forsse, A | 1 |
| Nielsen, TH | 2 |
| Mølstrøm, S | 1 |
| Hjelmborg, J | 1 |
| Nielsen, KS | 1 |
| Nygaard, KH | 1 |
| Yilmaz, S | 1 |
| Nordström, CH | 2 |
| Poulsen, FR | 1 |
| Cesak, T | 1 |
| Adamkov, J | 1 |
| Habalova, J | 1 |
| Poczos, P | 1 |
| Kanta, M | 1 |
| Bartos, M | 1 |
| Hosszu, T | 1 |
| Kofler, M | 1 |
| Gaasch, M | 1 |
| Rass, V | 1 |
| Schiefecker, AJ | 1 |
| Ianosi, B | 1 |
| Lindner, A | 1 |
| Beer, R | 2 |
| Stover, JF | 2 |
| Rhomberg, P | 1 |
| Pfausler, B | 2 |
| Thomé, C | 2 |
| Schmutzhard, E | 2 |
| Helbok, R | 2 |
| Schiefecker, A | 1 |
| Delazer, M | 1 |
| Bodner, T | 1 |
| Benke, T | 1 |
| Lackner, P | 1 |
| Fischer, M | 1 |
| Sohm, F | 1 |
| Hackl, W | 1 |
| Humpel, C | 1 |
| Jacobsen, A | 1 |
| Nilsson, O | 1 |
| Schalén, W | 1 |
| Tholance, Y | 1 |
| Barcelos, GK | 1 |
| Dailler, F | 1 |
| Renaud, B | 1 |
| Marinesco, S | 1 |
| Perret-Liaudet, A | 1 |
| Patet, C | 1 |
| Quintard, H | 1 |
| Zerlauth, JB | 1 |
| Maibach, T | 1 |
| Carteron, L | 1 |
| Suys, T | 1 |
| Bouzat, P | 1 |
| Bervini, D | 1 |
| Levivier, M | 1 |
| Daniel, RT | 1 |
| Eckert, P | 1 |
| Meuli, R | 1 |
| Oddo, M | 1 |
| Kinoshita, K | 1 |
| Moriya, T | 1 |
| Utagawa, A | 1 |
| Sakurai, A | 1 |
| Mukoyama, T | 1 |
| Furukawa, M | 1 |
| Yamaguchi, J | 1 |
| Tanjoh, K | 1 |
| Kett-White, R | 2 |
| Hutchinson, PJ | 2 |
| al-Rawi, PG | 2 |
| Gupta, AK | 2 |
| O'Connell, MT | 1 |
| Pickard, JD | 2 |
| Kirkpatrick, PJ | 2 |
| Cesarini, KG | 1 |
| Enblad, P | 1 |
| Ronne-Engström, E | 1 |
| Marklund, N | 1 |
| Salci, K | 1 |
| Nilsson, P | 1 |
| Hårdemark, HG | 1 |
| Hillered, L | 1 |
| Persson, L | 1 |
| Hoelper, BM | 1 |
| Hofmann, E | 1 |
| Sporleder, R | 1 |
| Soldner, F | 1 |
| Behr, R | 1 |
| Sarrafzadeh, A | 1 |
| Haux, D | 1 |
| Küchler, I | 1 |
| Lanksch, WR | 1 |
| Unterberg, AW | 1 |
| Eide, PK | 1 |
| Bentsen, G | 1 |
| Stanisic, M | 1 |
| Stubhaug, A | 1 |
| Mori, K | 1 |
| Nakajima, K | 1 |
| Maeda, M | 1 |
| Nilsson, OG | 1 |
| Brandt, L | 1 |
| Ungerstedt, U | 1 |
| Säveland, H | 1 |
| Czosnyka, M | 1 |
| Ryba, M | 1 |
| Johansson, K | 1 |
| Cybulska, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.[NCT03314779] | 12 participants (Actual) | Observational | 2017-08-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for pyruvic acid and Intracranial Aneurysm
| Article | Year |
|---|---|
Poor-grade aneurysmal subarachnoid hemorrhage: relationship of cerebral metabolism to outcome.
Topics: Brain; Disability Evaluation; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Humans; Hyperglyce | 2004 |
Cerebral oxygen and microdialysis monitoring during aneurysm surgery: effects of blood pressure, cerebrospinal fluid drainage, and temporary clipping on infarction.
Topics: Adult; Aged; Blood Pressure; Cerebral Infarction; Cerebrospinal Fluid; Drainage; Female; Glucose; Gl | 2002 |
15 other studies available for pyruvic acid and Intracranial Aneurysm
| Article | Year |
|---|---|
A Prospective Observational Feasibility Study of Jugular Bulb Microdialysis in Subarachnoid Hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Cerebrovascular Circulation; Feasibility Studies | 2020 |
The relationship between intracranial pressure and lactate/pyruvate ratio in patients with subarachnoid haemorrhage.
Topics: Aneurysm, Ruptured; Brain; Humans; Intracranial Aneurysm; Intracranial Hypertension; Intracranial Pr | 2018 |
The Importance of Probe Location for the Interpretation of Cerebral Microdialysis Data in Subarachnoid Hemorrhage Patients.
Topics: Aged; Aneurysm, Ruptured; Brain; Brain Edema; Brain Ischemia; Cohort Studies; Female; Glucose; Gluta | 2020 |
Cerebral tau is elevated after aneurysmal subarachnoid haemorrhage and associated with brain metabolic distress and poor functional and cognitive long-term outcome.
Topics: Aged; Biomarkers; Brain; Cognition Disorders; Female; Follow-Up Studies; Glutamic Acid; Humans; Intr | 2015 |
Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage.
Topics: Aged; Biomarkers; Brain Ischemia; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Human | 2014 |
Biochemical neuromonitoring of poor-grade aneurysmal subarachnoid hemorrhage: comparative analysis of metabolic events detected by cerebral microdialysis and by retrograde jugular vein catheterization.
Topics: Adolescent; Adult; Biomarkers; Brain; Catheterization; Female; Glasgow Outcome Scale; Humans; Intrac | 2015 |
Bedside cerebral microdialysis monitoring of delayed cerebral hypoperfusion in comatose patients with poor grade aneurysmal subarachnoid haemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Blood Glucose; Brain; Brain Ischemia; Cohort Studies; Coma; Critica | 2017 |
Change in brain glucose after enteral nutrition in subarachnoid hemorrhage.
Topics: Aged; Blood Flow Velocity; Blood Glucose; Blood Pressure; Brain; Enteral Nutrition; Glucose; Glutami | 2010 |
Extracellular lactate/pyruvate and glutamate changes in patients during per-operative episodes of cerebral ischaemia.
Topics: Adult; Aged; Biomarkers; Brain; Brain Ischemia; Carotid Artery, Internal; Craniotomy; Glutamic Acid; | 2002 |
Early cerebral hyperglycolysis after subarachnoid haemorrhage correlates with favourable outcome.
Topics: Adolescent; Adult; Aged; Blood Glucose; Brain; Embolization, Therapeutic; Energy Metabolism; Female; | 2002 |
Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case report.
Topics: Adult; Angioplasty, Balloon; Blood Flow Velocity; Blood Glucose; Brain; Carotid Artery, Internal; Ca | 2003 |
Association between intracranial pulse pressure levels and brain energy metabolism in a patient with an aneurysmal subarachnoid haemorrhage.
Topics: Aged; Brain; Brain Ischemia; Female; Glutamic Acid; Glycerol; Humans; Intracranial Aneurysm; Intracr | 2007 |
Long-term monitoring of CSF lactate levels and lactate/pyruvate ratios following subarachnoid haemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Bicarbonates; Female; Humans; Hydrogen-Ion Concentration; Intracran | 1993 |
Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain Ischemia; Cerebral Cortex; Female; Glutamic Acid; Glyc | 1999 |
Brain metabolism in deep controlled hypotension in neurosurgical patients.
Topics: Adult; Brain; Female; Humans; Hypotension, Controlled; Intracranial Aneurysm; L-Lactate Dehydrogenas | 1985 |