pyruvic acid has been researched along with Insulinoma in 9 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horiuchi, Y | 1 |
| Nakatsu, D | 1 |
| Kano, F | 1 |
| Murata, M | 1 |
| Barlow, J | 1 |
| Solomon, TPJ | 1 |
| Affourtit, C | 1 |
| Goehring, I | 1 |
| Gerencser, AA | 1 |
| Schmidt, S | 1 |
| Brand, MD | 1 |
| Mulder, H | 1 |
| Nicholls, DG | 1 |
| Sheline, CT | 1 |
| Shi, C | 1 |
| Takata, T | 1 |
| Zhu, J | 1 |
| Zhang, W | 1 |
| Sheline, PJ | 1 |
| Cai, AL | 1 |
| Li, L | 1 |
| Chang, I | 1 |
| Cho, N | 1 |
| Koh, JY | 1 |
| Lee, MS | 1 |
| MacDonald, MJ | 1 |
| Fahien, LA | 1 |
| Buss, JD | 1 |
| Hasan, NM | 1 |
| Fallon, MJ | 1 |
| Kendrick, MA | 1 |
| Joseph, JW | 1 |
| Odegaard, ML | 1 |
| Ronnebaum, SM | 1 |
| Burgess, SC | 1 |
| Muehlbauer, J | 1 |
| Sherry, AD | 1 |
| Newgard, CB | 1 |
| Ishihara, H | 1 |
| Wang, H | 1 |
| Drewes, LR | 1 |
| Wollheim, CB | 1 |
| Hale, PJ | 1 |
| Nattrass, M | 1 |
9 other studies available for pyruvic acid and Insulinoma
| Article | Year |
|---|---|
Pyruvate kinase M1 interacts with A-Raf and inhibits endoplasmic reticulum stress-induced apoptosis by activating MEK1/ERK pathway in mouse insulinoma cells.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Butadienes; Carrier Proteins; Caspase 3; Caspase 9; Cell | 2017 |
Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity - Novel mechanistic insight from real-time analysis of oxidative phosphorylation.
Topics: Adenosine Triphosphate; Animals; Cell Respiration; Cytokines; Glucose; Insulin; Insulin-Secreting Ce | 2018 |
Plasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line, Tumor; Dose-Response Relationship, Drug; Energy | 2012 |
Dietary zinc reduction, pyruvate supplementation, or zinc transporter 5 knockout attenuates β-cell death in nonobese diabetic mice, islets, and insulinoma cells.
Topics: Animals; Benzamides; Calcium Channel Blockers; Carrier Proteins; Cell Line, Tumor; Diabetes Mellitus | 2012 |
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes.
Topics: Adenosine Triphosphate; Animals; Antigens, Polyomavirus Transforming; Antioxidants; Cell Death; Cell | 2003 |
Citrate oscillates in liver and pancreatic beta cell mitochondria and in INS-1 insulinoma cells.
Topics: Animals; Biological Clocks; Cell Line, Tumor; Citric Acid; Glucose; Hepatocytes; Insulinoma; Islets | 2003 |
Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion.
Topics: Adenoviridae; Animals; ATP Citrate (pro-S)-Lyase; Carbon Isotopes; Cell Line, Tumor; Fatty Acid Synt | 2007 |
Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells.
Topics: Adenoviridae; Animals; Carrier Proteins; Cell Line; Fluoresceins; Fluorescent Antibody Technique; Ge | 1999 |
Metabolic profiles in patients with insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Alanine; Blood Glucose; Fatty Acids, Nonesterified; Female; Glycer | 1989 |