pyruvic acid has been researched along with Hypoxia-Ischemia, Brain in 11 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, VHS | 1 |
| Gugino, S | 1 |
| Nielsen, L | 1 |
| Chandrasekharan, P | 1 |
| Koenigsknecht, C | 1 |
| Helman, J | 1 |
| Lakshminrusimha, S | 1 |
| Sánchez-Illana, Á | 1 |
| Núñez-Ramiro, A | 1 |
| Cernada, M | 1 |
| Parra-Llorca, A | 1 |
| Valverde, E | 1 |
| Blanco, D | 1 |
| Moral-Pumarega, MT | 1 |
| Cabañas, F | 1 |
| Boix, H | 1 |
| Pavon, A | 1 |
| Chaffanel, M | 1 |
| Benavente-Fernández, I | 1 |
| Tofe, I | 1 |
| Loureiro, B | 1 |
| Fernández-Lorenzo, JR | 1 |
| Fernández-Colomer, B | 1 |
| García-Robles, A | 1 |
| Kuligowski, J | 1 |
| Vento, M | 1 |
| Takenouchi, T | 1 |
| Sugiura, Y | 1 |
| Morikawa, T | 1 |
| Nakanishi, T | 1 |
| Nagahata, Y | 1 |
| Sugioka, T | 1 |
| Honda, K | 1 |
| Kubo, A | 1 |
| Hishiki, T | 1 |
| Matsuura, T | 1 |
| Hoshino, T | 1 |
| Takahashi, T | 1 |
| Suematsu, M | 1 |
| Kajimura, M | 1 |
| Liu, A | 1 |
| Zhang, Z | 1 |
| Li, A | 1 |
| Xue, J | 1 |
| Bhargava, D | 1 |
| Al-Tamimi, Y | 1 |
| Quinn, A | 1 |
| Ross, S | 1 |
| Larach, DB | 1 |
| Kofke, WA | 1 |
| Le Roux, P | 1 |
| Schurr, A | 1 |
| Lyng, K | 1 |
| Munkeby, BH | 2 |
| Saugstad, OD | 2 |
| Stray-Pedersen, B | 2 |
| Frøen, JF | 2 |
| Homola, A | 1 |
| Zoremba, N | 1 |
| Slais, K | 1 |
| Kuhlen, R | 1 |
| Syková, E | 1 |
| Engidawork, E | 1 |
| Loidl, F | 1 |
| Chen, Y | 1 |
| Kohlhauser, C | 1 |
| Stoeckler, S | 1 |
| Dell'Anna, E | 1 |
| Lubec, B | 1 |
| Lubec, G | 1 |
| Goiny, M | 1 |
| Gross, J | 1 |
| Andersson, K | 1 |
| Herrera-Marschitz, M | 1 |
1 review available for pyruvic acid and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Lactate, glucose and energy metabolism in the ischemic brain (Review).
Topics: Acidosis, Lactic; Anaerobiosis; Animals; Brain; Brain Damage, Chronic; Brain Ischemia; Corticosteron | 2002 |
1 trial available for pyruvic acid and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Evolution of Energy Related Metabolites in Plasma from Newborns with Hypoxic-Ischemic Encephalopathy during Hypothermia Treatment.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Biomarkers; Case-Control Studies; Female; Gas Chromatography-M | 2017 |
9 other studies available for pyruvic acid and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Protection from systemic pyruvate at resuscitation in newborn lambs with asphyxial cardiac arrest.
Topics: Animals; Animals, Newborn; Asphyxia; Blood Pressure; Disease Models, Animal; Heart Arrest; Hypoxia-I | 2020 |
Therapeutic hypothermia achieves neuroprotection via a decrease in acetylcholine with a concurrent increase in carnitine in the neonatal hypoxia-ischemia.
Topics: Acetyl Coenzyme A; Acetylcholine; Amino Acids; Amygdala; Animals; Animals, Newborn; Carnitine; Glyco | 2015 |
Effects of hypothermia and cerebral ischemia on cold-inducible RNA-binding protein mRNA expression in rat brain.
Topics: Analysis of Variance; Animals; Brain; Cold Temperature; Disease Models, Animal; Energy Metabolism; G | 2010 |
New modalities to assess efficacy of triple-h therapy: early experience.
Topics: Blood Pressure; Blood Volume; Cerebrovascular Circulation; Hemodilution; Humans; Hypoxia-Ischemia, B | 2011 |
Potential non-hypoxic/ischemic causes of increased cerebral interstitial fluid lactate/pyruvate ratio: a review of available literature.
Topics: Aerobiosis; Anaerobiosis; Blood Glucose; Brain; Brain Injuries; Critical Care; Energy Metabolism; Ex | 2011 |
Effect of interleukin-10 on newborn piglet brain following hypoxia-ischemia and endotoxin-induced inflammation.
Topics: Animals; Animals, Newborn; Area Under Curve; Brain; Cerebrovascular Circulation; Encephalitis; Endot | 2005 |
Changes in diffusion parameters, energy-related metabolites and glutamate in the rat cortex after transient hypoxia/ischemia.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Energy Metabolism; Extracellular Space; Glucose; G | 2006 |
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Behavior, Ani | 2001 |
Interleukin-10 reverses acute detrimental effects of endotoxin-induced inflammation on perinatal cerebral hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Bacterial Infections; Blood Pressure; Brain; Cerebral Palsy; Encephalitis | 2002 |