pyruvic acid has been researched along with Hyperoxia in 11 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Hyperoxia: An abnormal increase in the amount of oxygen in the tissues and organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levels of 3-phosphoglyceric acid, 2-phosphoglyceric acid, phosphoenolpyruvic acid, and lactic acid were significantly elevated in the lungs of hyperoxia-exposed versus normoxia-exposed adult mice, whereas no significant differences were observed with hyperoxia exposure in neonatal mice." | 7.96 | Difference in pyruvic acid metabolism between neonatal and adult mouse lungs exposed to hyperoxia. ( Arai, Y; Itakura, R; Ito, M; Kobayashi, S; Matsumura, S; Miyake, F; Nagano, N; Namba, F; Ozawa, J; Tanaka, K; Watanabe, T, 2020) |
| "This study investigated whether increased muscle acetylcarnitine provision (acetate infusion) or hyperoxia (100% O(2)) would increase the rate of oxidative phosphorylation and reduce the reliance on muscle substrate phosphorylation after the onset of moderate exercise." | 5.09 | Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise. ( Evans, MK; Heigenhauser, GJ; Savasi, I; Spriet, LL, 2001) |
| "Hyperoxia was associated with a higher sublingual microcirculatory flow over time, with higher cerebral perfusion and brain tissue oxygen pressure and with a lower cerebral lactate-to-pyruvate ratio than in control animals." | 1.46 | Should Hyperoxia Be Avoided During Sepsis? An Experimental Study in Ovine Peritonitis. ( Donadello, K; He, X; Su, F; Taccone, FS; Vincent, JL; Xie, K, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Giannì, G | 1 |
| Minini, A | 1 |
| Fratino, S | 1 |
| Peluso, L | 1 |
| Annoni, F | 1 |
| Oddo, M | 1 |
| Schuind, S | 1 |
| Creteur, J | 1 |
| Taccone, FS | 2 |
| Bogossian, EG | 1 |
| Tanaka, K | 1 |
| Watanabe, T | 1 |
| Ozawa, J | 1 |
| Ito, M | 1 |
| Nagano, N | 1 |
| Arai, Y | 1 |
| Miyake, F | 1 |
| Matsumura, S | 1 |
| Kobayashi, S | 1 |
| Itakura, R | 1 |
| Namba, F | 1 |
| He, X | 1 |
| Su, F | 1 |
| Xie, K | 1 |
| Donadello, K | 1 |
| Vincent, JL | 1 |
| Ghosh, A | 2 |
| Highton, D | 2 |
| Kolyva, C | 2 |
| Tachtsidis, I | 3 |
| Elwell, CE | 2 |
| Smith, M | 3 |
| Tisdall, MM | 1 |
| Leung, TS | 1 |
| Elwell, C | 1 |
| Stellingwerff, T | 1 |
| Leblanc, PJ | 1 |
| Hollidge, MG | 1 |
| Heigenhauser, GJ | 2 |
| Spriet, LL | 2 |
| Audonnet-Blaise, S | 1 |
| Krafft, MP | 1 |
| Smani, Y | 1 |
| Mertes, PM | 1 |
| Marie, PY | 1 |
| Labrude, P | 1 |
| Longrois, D | 1 |
| Menu, P | 1 |
| Henderson, GC | 1 |
| Horning, MA | 1 |
| Wallis, GA | 1 |
| Brooks, GA | 1 |
| Nortje, J | 1 |
| Coles, JP | 1 |
| Timofeev, I | 1 |
| Fryer, TD | 1 |
| Aigbirhio, FI | 1 |
| Smielewski, P | 1 |
| Outtrim, JG | 1 |
| Chatfield, DA | 1 |
| Pickard, JD | 1 |
| Hutchinson, PJ | 1 |
| Gupta, AK | 1 |
| Menon, DK | 1 |
| Evans, MK | 1 |
| Savasi, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Continuous, Non-invasive Monitoring of Intraoperative Cerebral Perfusion and Oxidative Metabolism (CPOM): a Knowledge Translation Study.[NCT03907904] | 40 participants (Anticipated) | Observational | 2019-07-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvic acid and Hyperoxia
| Article | Year |
|---|---|
The Impact of Short-Term Hyperoxia on Cerebral Metabolism: A Systematic Review and Meta-Analysis.
Topics: Brain Injuries; Glucose; Humans; Hyperoxia; Lactic Acid; Microdialysis; Observational Studies as Top | 2022 |
3 trials available for pyruvic acid and Hyperoxia
| Article | Year |
|---|---|
Increase in cerebral aerobic metabolism by normobaric hyperoxia after traumatic brain injury.
Topics: Adult; Brain Injuries; Female; Humans; Hyperoxia; Lactic Acid; Male; Microdialysis; Middle Aged; Oxi | 2008 |
Hyperoxia decreases muscle glycogenolysis, lactate production, and lactate efflux during steady-state exercise.
Topics: Adult; Blood Gas Analysis; Exercise; Glucose; Glycogenolysis; Humans; Hyperoxia; In Vitro Techniques | 2006 |
Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise.
Topics: Acetates; Acetyl Coenzyme A; Acetylcarnitine; Adenosine Diphosphate; Adenosine Monophosphate; Adult; | 2001 |
7 other studies available for pyruvic acid and Hyperoxia
| Article | Year |
|---|---|
Difference in pyruvic acid metabolism between neonatal and adult mouse lungs exposed to hyperoxia.
Topics: Age Factors; Animals; Animals, Newborn; Gene Expression; Gluconeogenesis; Glycolysis; Hyperoxia; Lun | 2020 |
Should Hyperoxia Be Avoided During Sepsis? An Experimental Study in Ovine Peritonitis.
Topics: Animals; Brain; Cerebrovascular Circulation; Female; Hyperoxia; Lactic Acid; Microcirculation; Model | 2017 |
Hyperoxia results in increased aerobic metabolism following acute brain injury.
Topics: Blood Flow Velocity; Brain; Brain Injuries; Cerebrovascular Circulation; Cytochromes c; Energy Metab | 2017 |
Normobaric hyperoxia does not change optical scattering or pathlength but does increase oxidised cytochrome C oxidase concentration in patients with brain injury.
Topics: Adult; Aged; Brain Injuries; Cerebrovascular Circulation; Electron Transport Complex IV; Female; Hem | 2013 |
Resuscitation of severe but brief haemorrhagic shock with PFC in rabbits restores skeletal muscle oxygen delivery and does not alter skeletal muscle metabolism.
Topics: Animals; Blood Pressure; Blood Substitutes; Disease Models, Animal; Fluorocarbons; Hyperoxia; Lactic | 2006 |
Pyruvate metabolism in working human skeletal muscle.
Topics: Exercise; Glycogenolysis; Humans; Hyperoxia; Lactic Acid; Muscle, Skeletal; Pyruvic Acid | 2007 |
Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings.
Topics: Adolescent; Adult; Brain Injuries; Cerebrum; Female; Humans; Hyperoxia; Intracranial Pressure; Lacti | 2008 |