pyruvic acid has been researched along with Heart Diseases in 12 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Above the anaerobic threshold, accelerated glycolysis increases muscle lactic acidosis." | 3.69 | Determination of the anaerobic threshold by gas exchange: biochemical considerations, methodology and physiological effects. ( Casaburi, R; Cooper, CB; Koike, A; Stringer, WW; Wasserman, K, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JM | 1 |
| Reed, GD | 1 |
| Liticker, J | 1 |
| Putnam, WC | 1 |
| Chandra, A | 1 |
| Yaros, K | 1 |
| Afzal, A | 1 |
| MacNamara, J | 1 |
| Raza, J | 1 |
| Hall, RG | 1 |
| Baxter, J | 1 |
| Derner, K | 1 |
| Pena, S | 1 |
| Kallem, RR | 1 |
| Subramaniyan, I | 1 |
| Edpuganti, V | 1 |
| Harrison, CE | 1 |
| Muthukumar, A | 1 |
| Lewis, C | 1 |
| Reddy, S | 1 |
| Unni, N | 1 |
| Klemow, D | 1 |
| Syed, S | 1 |
| Li, H | 1 |
| Cole, S | 1 |
| Froehlich, T | 1 |
| Ayers, C | 1 |
| de Lemos, J | 1 |
| Malloy, CR | 1 |
| Haley, B | 1 |
| Zaha, VG | 1 |
| Rider, OJ | 1 |
| Tyler, DJ | 1 |
| Gray, LR | 1 |
| Tompkins, SC | 1 |
| Taylor, EB | 1 |
| Ryou, MG | 1 |
| Flaherty, DC | 1 |
| Hoxha, B | 1 |
| Sun, J | 1 |
| Gurji, H | 1 |
| Rodriguez, S | 1 |
| Bell, G | 1 |
| Olivencia-Yurvati, AH | 1 |
| Mallet, RT | 1 |
| TWRDY, E | 1 |
| VALLE ZARATE, VC | 1 |
| HARRIS, P | 1 |
| BAILEY, T | 1 |
| BATEMAN, M | 1 |
| FITZGERALD, MG | 1 |
| GLOSTER, J | 1 |
| HARRIS, EA | 1 |
| DONALD, KW | 1 |
| Watanabe, S | 1 |
| Ajisaka, R | 1 |
| Masuoka, T | 1 |
| Yamanouchi, T | 1 |
| Saitou, T | 1 |
| Toyama, M | 1 |
| Takeyasu, N | 1 |
| Sakamoto, K | 1 |
| Sugishita, Y | 1 |
| Wasserman, K | 2 |
| Stringer, WW | 1 |
| Casaburi, R | 1 |
| Koike, A | 1 |
| Cooper, CB | 1 |
| Floria, VG | 1 |
| Mareev, VIu | 1 |
| Munnich, A | 1 |
| Rustin, P | 1 |
| Rötig, A | 1 |
| Chretien, D | 1 |
| Bonnefont, JP | 1 |
| Nuttin, C | 1 |
| Cormier, V | 1 |
| Vassault, A | 1 |
| Parvy, P | 1 |
| Bardet, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hyperpolarized MRSI in Ischemic Heart Disease: Metabolic Profiling of the Myocardium[NCT06054516] | 15 participants (Anticipated) | Observational | 2023-10-13 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for pyruvic acid and Heart Diseases
| Article | Year |
|---|---|
Clinical implications of cardiac hyperpolarized magnetic resonance imaging.
Topics: Animals; Carbon Isotopes; Energy Metabolism; Heart Diseases; Humans; Magnetic Resonance Imaging; Mag | 2013 |
Regulation of pyruvate metabolism and human disease.
Topics: Citric Acid Cycle; Cytosol; Heart Diseases; Humans; Mitochondria; Models, Biological; Neoplasms; Neu | 2014 |
[Anaerobic threshold: definition, physiology and methods of determination].
Topics: Anaerobic Threshold; Blood Gas Analysis; Exercise Test; Heart Diseases; Humans; Lactates; Lactic Aci | 1993 |
The anaerobic threshold: definition, physiological significance and identification.
Topics: Acidosis; Adult; Anaerobiosis; Glycolysis; Heart Diseases; Humans; Kinetics; Lactates; Lactic Acid; | 1986 |
1 trial available for pyruvic acid and Heart Diseases
| Article | Year |
|---|---|
Effects of L- and DL-carnitine on patients with impaired exercise tolerance.
Topics: Administration, Oral; Aged; Cardiac Output; Carnitine; Exercise Test; Exercise Tolerance; Female; He | 1995 |
7 other studies available for pyruvic acid and Heart Diseases
| Article | Year |
|---|---|
Effect of Doxorubicin on Myocardial Bicarbonate Production From Pyruvate Dehydrogenase in Women With Breast Cancer.
Topics: Adult; Antibiotics, Antineoplastic; Bicarbonates; Breast Neoplasms; Carbon-13 Magnetic Resonance Spe | 2020 |
Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass.
Topics: Animals; Blood Pressure; Cardioplegic Solutions; Cardiopulmonary Bypass; Edema, Cardiac; Energy Meta | 2009 |
[Activity of serum glutamic pyruvic acid transminases; determination by means of a modified paper chromatographic method and clinical results, especially in heart diseases].
Topics: Glutamic Acid; Heart; Heart Diseases; Hematologic Diseases; Liver Function Tests; Pyruvic Acid; Tran | 1957 |
[Action of thiamine on the blood pyruvic acid in liver diseases and heart diseases].
Topics: Heart Diseases; Humans; Liver Diseases; Pyruvates; Pyruvic Acid; Thiamine; Vascular Diseases | 1959 |
LACTATE, PYRUVATE, GLUCOSE, AND FREE FATTY ACID IN MIXED VENOUS AND ARTERIAL BLOOD.
Topics: Blood Chemical Analysis; Blood Glucose; Brachial Artery; Cardiac Catheterization; Fatty Acids; Fatty | 1963 |
Determination of the anaerobic threshold by gas exchange: biochemical considerations, methodology and physiological effects.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; Anaerobic Threshold; Bicarbonates; Carbon Dioxide; E | 1994 |
Clinical aspects of mitochondrial disorders.
Topics: Child, Preschool; Coma; Diabetes Mellitus; DNA, Mitochondrial; Dwarfism; Female; Heart Diseases; Hum | 1992 |