pyruvic acid has been researched along with Heart Disease, Ischemic in 53 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For glycerol, there was a further increase at reperfusion." | 5.33 | Myocardial glycerol release, arrhythmias and hemodynamic instability during regional ischemia-reperfusion in an open chest pig model. ( Algotsson, L; Liao, Q; Metzsch, C; Steen, S, 2006) |
| "In 70 mechanically-ventilated patients with septic shock, we examined: a) S' and E' mitral annular velocities using tissue Doppler imaging (TDI), b) CFR of the left anterior descending artery after adenosine infusion using transesophageal Doppler echocardiography and c) lactate, pyruvate and glycerol in tissue by means of a microdialysis (MD) catheter inserted into the subcutaneous adipose tissue as markers of tissue ischemia and acidosis." | 3.80 | Coronary flow reserve is associated with tissue ischemia and is an additive predictor of intensive care unit mortality to traditional risk scores in septic shock. ( Armaganidis, A; Diamantakis, A; Dimopoulou, I; Ikonomidis, I; Kopterides, P; Lekakis, J; Makavos, G; Nikitas, N; Paraskevaidis, I; Parissis, J; Theodorakopoulou, M, 2014) |
| "Levosimendan used throughout myocardial ischemia-reperfusion might have a cardioprotective affect on the response to myocardial ischemia as compared with levosimendan started during the ischemia." | 3.74 | Levosimendan cardioprotection reduces the metabolic response during temporary regional coronary occlusion in an open chest pig model. ( Algotsson, L; Liao, Q; Metzsch, C; Steen, S, 2007) |
| "In this study, we demonstrated stereoselective differences in the biologic action of the two ketamine isomers in an animal model of myocardial ischemia." | 3.70 | S(+)-ketamine, but not R(-)-ketamine, reduces postischemic adherence of neutrophils in the coronary system of isolated guinea pig hearts. ( Becker, BF; Conzen, PF; Heindl, B; Szekely, A; Zahler, S, 1999) |
| "Niacin, known to lower cytosolic NADH/NAD+ ratio independent of the aldose reductase pathway inhibition, also blocked JAK2 and STAT5 activation." | 1.33 | Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury. ( Hwang, YC; Kaneko, M; Marrero, MB; Ramasamy, R; Redd, H; Shaw, S, 2005) |
| "For glycerol, there was a further increase at reperfusion." | 1.33 | Myocardial glycerol release, arrhythmias and hemodynamic instability during regional ischemia-reperfusion in an open chest pig model. ( Algotsson, L; Liao, Q; Metzsch, C; Steen, S, 2006) |
| "Glycerol was progressively released during prolonged ischemia." | 1.31 | Monitoring of porcine myocardial ischemia and reperfusion by intravasal microdialysis. ( Bäckström, T; Franco-Cereceda, A; Liska, J; Lockowandt, U; Sylven, C, 2002) |
| "Adenosine appeared to be a more sensitive marker of early ischaemia than lactate, although interestingly, adenosine levels had decreased already after 15 min, most probably due to intracellular accumulation of protons and Pi." | 1.29 | Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig. ( Maripu, E; Nilsson, S; Ronquist, G; Waldenström, A; Wikström, G, 1995) |
| "Glycogen depletion by anoxia or glucagon before ischemia impaired recovery." | 1.29 | Metabolic recovery of isolated working rat heart after brief global ischemia. ( Goodwin, GW; Taegtmeyer, H, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (43.40) | 18.2507 |
| 2000's | 23 (43.40) | 29.6817 |
| 2010's | 7 (13.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikonomidis, I | 1 |
| Makavos, G | 1 |
| Nikitas, N | 1 |
| Paraskevaidis, I | 1 |
| Diamantakis, A | 1 |
| Kopterides, P | 1 |
| Theodorakopoulou, M | 1 |
| Parissis, J | 1 |
| Lekakis, J | 1 |
| Armaganidis, A | 1 |
| Dimopoulou, I | 1 |
| Lau, AZ | 2 |
| Miller, JJ | 1 |
| Tyler, DJ | 3 |
| Schroeder, MA | 2 |
| Atherton, HJ | 2 |
| Ball, DR | 1 |
| Cole, MA | 1 |
| Heather, LC | 1 |
| Griffin, JL | 1 |
| Clarke, K | 2 |
| Radda, GK | 2 |
| Mantovani, V | 2 |
| Kennergren, C | 1 |
| Bugge, M | 1 |
| Sala, A | 1 |
| Lönnroth, P | 1 |
| Berglin, E | 1 |
| Ahlström, K | 1 |
| Biber, B | 1 |
| Aberg, A | 1 |
| Waldenström, A | 5 |
| Ronquist, G | 4 |
| Abrahamsson, P | 2 |
| Strandén, P | 1 |
| Johansson, G | 2 |
| Haney, MF | 1 |
| Metzsch, C | 3 |
| Linnér, R | 1 |
| Steen, S | 3 |
| Liao, Q | 3 |
| Algotsson, L | 3 |
| Swietach, P | 1 |
| Gallagher, FA | 1 |
| Lee, P | 1 |
| Aberg, AM | 1 |
| Winsö, O | 1 |
| Haney, M | 1 |
| Chen, AP | 1 |
| Barry, J | 1 |
| Graham, JJ | 1 |
| Dominguez-Viqueira, W | 1 |
| Ghugre, NR | 1 |
| Wright, GA | 1 |
| Cunningham, CH | 1 |
| Monteiro, P | 1 |
| Duarte, A | 1 |
| Moreno, A | 1 |
| Gonçalves, L | 1 |
| Providência, LA | 1 |
| Satoh, K | 1 |
| Takeda, S | 1 |
| Kaneta, S | 1 |
| Inagami, T | 1 |
| Ichihara, K | 2 |
| Stanley, WC | 3 |
| Kivilo, KM | 1 |
| Panchal, AR | 1 |
| Hallowell, PH | 1 |
| Bomont, C | 1 |
| Kasumov, T | 1 |
| Brunengraber, H | 1 |
| Olivencia-Yurvati, AH | 1 |
| Blair, JL | 1 |
| Baig, M | 1 |
| Mallet, RT | 1 |
| Salem, JE | 1 |
| Cabrera, ME | 1 |
| Hwang, YC | 1 |
| Shaw, S | 1 |
| Kaneko, M | 1 |
| Redd, H | 1 |
| Marrero, MB | 1 |
| Ramasamy, R | 2 |
| Runge, M | 1 |
| Hughes, P | 1 |
| Peter Gøtze, J | 1 |
| Petersen, RH | 1 |
| Steinbrüchel, DA | 1 |
| Gonsolin, D | 1 |
| Couturier, K | 1 |
| Garait, B | 1 |
| Rondel, S | 1 |
| Novel-Chaté, V | 1 |
| Peltier, S | 1 |
| Faure, P | 1 |
| Gachon, P | 1 |
| Boirie, Y | 1 |
| Keriel, C | 1 |
| Favier, R | 1 |
| Pepe, S | 1 |
| Demaison, L | 2 |
| Leverve, X | 1 |
| Carvajal, K | 1 |
| Zarrinpashneh, E | 1 |
| Szarszoi, O | 1 |
| Joubert, F | 1 |
| Athea, Y | 1 |
| Mateo, P | 1 |
| Gillet, B | 1 |
| Vaulont, S | 1 |
| Viollet, B | 1 |
| Bigard, X | 1 |
| Bertrand, L | 1 |
| Ventura-Clapier, R | 1 |
| Hoerter, JA | 1 |
| Pöling, J | 1 |
| Rees, W | 1 |
| Klaus, S | 1 |
| Bahlmann, L | 1 |
| Hübner, N | 1 |
| Heringlake, M | 1 |
| Warnecke, H | 1 |
| Golman, K | 1 |
| Petersson, JS | 1 |
| Magnusson, P | 1 |
| Johansson, E | 1 |
| Akeson, P | 1 |
| Chai, CM | 1 |
| Hansson, G | 1 |
| Månsson, S | 1 |
| Chew, MS | 1 |
| Johansson, A | 1 |
| Anderson, C | 1 |
| Ersson, A | 1 |
| Tønnesen, E | 1 |
| Sumegi, B | 2 |
| Podanyi, B | 1 |
| Forgo, P | 1 |
| Kover, KE | 1 |
| Armstrong, S | 1 |
| Ganote, CE | 1 |
| de Groot, MJ | 3 |
| van Helden, MA | 1 |
| de Jong, YF | 1 |
| Coumans, WA | 2 |
| van der Vusse, GJ | 3 |
| Wikström, BG | 1 |
| Wikström, G | 2 |
| Nilsson, S | 1 |
| Maripu, E | 1 |
| Butwell, NB | 1 |
| Malloy, CR | 2 |
| Sherry, AD | 2 |
| Goodwin, GW | 1 |
| Taegtmeyer, H | 1 |
| Willemsen, PH | 1 |
| Goto, M | 1 |
| Tsuchida, A | 1 |
| Liu, Y | 1 |
| Cohen, MV | 1 |
| Downey, JM | 1 |
| Schaefer, S | 2 |
| Prussel, E | 1 |
| Carr, LJ | 1 |
| Bindoli, A | 1 |
| Barzon, E | 1 |
| Rigobello, MP | 1 |
| Fujita, S | 1 |
| Tsuchida, H | 1 |
| Kanaya, N | 1 |
| Kokita, N | 1 |
| Kawamata, M | 1 |
| Namiki, A | 1 |
| Barak, C | 1 |
| Reed, MK | 1 |
| Maniscalco, SP | 1 |
| Jessen, ME | 1 |
| Saiki, Y | 1 |
| Lopaschuk, GD | 1 |
| Dodge, K | 1 |
| Yamaya, K | 1 |
| Morgan, C | 1 |
| Rebeyka, IM | 1 |
| Chen, W | 1 |
| London, R | 1 |
| Murphy, E | 1 |
| Steenbergen, C | 1 |
| van Emous, JG | 1 |
| Lankamp, CL | 1 |
| Ruigrok, TJ | 1 |
| van Echteld, CJ | 1 |
| Kerr, PM | 1 |
| Suleiman, MS | 1 |
| Halestrap, AP | 1 |
| Szekely, A | 1 |
| Heindl, B | 2 |
| Zahler, S | 1 |
| Conzen, PF | 1 |
| Becker, BF | 2 |
| Dunphy, G | 1 |
| Richter, HW | 1 |
| Azodi, M | 1 |
| Weigand, J | 1 |
| Sadri, F | 1 |
| Sellke, F | 1 |
| Ely, D | 1 |
| White, LT | 1 |
| O'Donnell, JM | 1 |
| Griffin, J | 1 |
| Lewandowski, ED | 1 |
| Dobsak, P | 1 |
| Courderot-Masuyer, C | 1 |
| Zeller, M | 1 |
| Vergely, C | 1 |
| Laubriet, A | 1 |
| Assem, M | 1 |
| Eicher, JC | 1 |
| Teyssier, JR | 1 |
| Wolf, JE | 1 |
| Rochette, L | 2 |
| Bassenge, E | 1 |
| Sommer, O | 1 |
| Schwemmer, M | 1 |
| Bünger, R | 1 |
| Zemgulis, V | 1 |
| Henze, A | 1 |
| Thelin, S | 1 |
| Moreau, D | 1 |
| Vergely-Vandriesse, C | 1 |
| Grégoire, S | 1 |
| Degois, M | 1 |
| Bäckström, T | 1 |
| Lockowandt, U | 1 |
| Liska, J | 1 |
| Sylven, C | 1 |
| Franco-Cereceda, A | 1 |
| Broderick, TL | 1 |
| Belke, T | 1 |
| Driedzic, WR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hyperpolarized MRSI in Ischemic Heart Disease: Metabolic Profiling of the Myocardium[NCT06054516] | 15 participants (Anticipated) | Observational | 2023-10-13 | Recruiting | |||
| Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514] | 2 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvic acid and Heart Disease, Ischemic
| Article | Year |
|---|---|
Myocardial energy metabolism during ischemia and the mechanisms of metabolic therapies.
Topics: Animals; Carbohydrate Metabolism; Double-Blind Method; Energy Metabolism; Fatty Acids; Glycolysis; H | 2004 |
2 trials available for pyruvic acid and Heart Disease, Ischemic
| Article | Year |
|---|---|
Myocardial metabolism assessed by microdialysis: a prospective randomized study in on- and off-pump coronary bypass surgery.
Topics: Aged; Biomarkers; Coronary Artery Bypass, Off-Pump; Energy Metabolism; Female; Glucose; Glycerol; Hu | 2010 |
Pyruvate-enhanced cardioprotection during surgery with cardiopulmonary bypass.
Topics: Aged; Cardioplegic Solutions; Cardiopulmonary Bypass; Cardiotonic Agents; Catecholamines; Coronary A | 2003 |
50 other studies available for pyruvic acid and Heart Disease, Ischemic
| Article | Year |
|---|---|
Coronary flow reserve is associated with tissue ischemia and is an additive predictor of intensive care unit mortality to traditional risk scores in septic shock.
Topics: Acidosis; Aged; APACHE; Blood Glucose; Coronary Circulation; Echocardiography, Doppler; Echocardiogr | 2014 |
Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1-13C]pyruvate.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Calcium Signaling; Carbon Dioxide; Carbon Iso | 2017 |
Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.
Topics: Acetylcarnitine; Animals; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Energy Metabolism; Glutam | 2009 |
Metabolic responses in ischemic myocardium after inhalation of carbon monoxide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Pressure; Carbon Monoxide; Carboxyhemo | 2009 |
Levosimendan cardioprotection in acutely beta-1 adrenergic receptor blocked open chest pigs.
Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Clinical Protocols; Female; Glucose; Glyce | 2010 |
Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study.
Topics: Animals; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Carbonic Anhydrases; Energy Metabolism; Hydr | 2010 |
Detection of myocardial ischaemia using surface microdialysis on the beating heart.
Topics: Animals; Biomarkers; Disease Models, Animal; Energy Metabolism; Female; Glucose; Glycerol; Lactic Ac | 2011 |
Reproducibility study for free-breathing measurements of pyruvate metabolism using hyperpolarized (13) C in the heart.
Topics: Animals; Carbon Isotopes; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Myocardial Ischemia; | 2013 |
Pyruvate improves mitochondrial bioenergetics in an ex-vivo animal model of myocardial ischemia.
Topics: Animals; Ascorbic Acid; Chemotherapy, Cancer, Regional Perfusion; Female; Glutamic Acid; Intracellul | 2003 |
Effects of nebivolol on ischemia-induced metabolic changes in dog hearts.
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Carbohydrate Metabolism; Dogs; Endothelium, Vascu | 2003 |
Post-ischemic treatment with dipyruvyl-acetyl-glycerol decreases myocardial infarct size in the pig.
Topics: Animals; Blood Pressure; Citric Acid Cycle; Dose-Response Relationship, Drug; Glycerol; Injections, | 2003 |
Computational studies of the effects of myocardial blood flow reductions on cardiac metabolism.
Topics: Adenosine Triphosphate; Glycogen; Glycolysis; Lactic Acid; Models, Cardiovascular; Myocardial Ischem | 2004 |
Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury.
Topics: Aldehyde Reductase; Animals; Blotting, Western; Enzyme Activation; Enzyme Inhibitors; Humans; Janus | 2005 |
Myocardial glycerol release, arrhythmias and hemodynamic instability during regional ischemia-reperfusion in an open chest pig model.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Coronary Circulation; Glucose; Glycer | 2006 |
Evaluation of myocardial metabolism with microdialysis after protection with cold blood- or cold crystalloid cardioplegia. A porcine model.
Topics: Animals; Cardioplegic Solutions; Female; Glycerol; Heart; Heart Arrest, Induced; Hypothermia, Induce | 2006 |
High dietary sucrose triggers hyperinsulinemia, increases myocardial beta-oxidation, reduces glycolytic flux and delays post-ischemic contractile recovery.
Topics: Animals; Blood Glucose; Body Weight; Dietary Sucrose; Glycolysis; Hyperinsulinism; In Vitro Techniqu | 2007 |
Levosimendan cardioprotection reduces the metabolic response during temporary regional coronary occlusion in an open chest pig model.
Topics: Animals; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Glucose; Hydrazones; Infusions, I | 2007 |
Dual cardiac contractile effects of the alpha2-AMPK deletion in low-flow ischemia and reperfusion.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cell Respiration; Creatine Kinase, M | 2007 |
Functional recovery of chronic ischemic myocardium after surgical revascularization correlates with magnitude of oxidative metabolism.
Topics: Coronary Artery Bypass; Coronary Circulation; Ethanol; Glucose; Humans; Lactic Acid; Magnetic Resona | 2008 |
Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI.
Topics: Animals; Carbon Isotopes; Contrast Media; Feasibility Studies; Gadolinium DTPA; Magnetic Resonance I | 2008 |
Decreases in myocardial glucose and increases in pyruvate but not ischaemia are observed during porcine endotoxaemia.
Topics: Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Endotoxemia; Glucose; Lactic Acid; M | 2008 |
Metabolism of [3-13C]pyruvate and [3-13C]propionate in normal and ischaemic rat heart in vivo: 1H- and 13C-NMR studies.
Topics: Acetyl Coenzyme A; Alanine; Animals; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; M | 1995 |
Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: evidence of A3 receptor involvement.
Topics: Adenosine; Animals; Antihypertensive Agents; Cells, Cultured; Glucose; Myocardial Infarction; Myocar | 1994 |
The influence of lactate, pyruvate and glucose as exogenous substrates on free radical defense mechanisms in isolated rat hearts during ischaemia and reperfusion.
Topics: Animals; Antioxidants; Catalase; Free Radicals; Glucose; Glutathione; Glutathione Peroxidase; Glutat | 1995 |
Dynamics of myocardial metabolism in the preconditioned porcine heart studied using continuous microdialysis.
Topics: Adenine Nucleotides; Animals; Cardiac Output; Chromatography, High Pressure Liquid; Disease Models, | 1995 |
Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig.
Topics: Adenosine; Animals; Energy Metabolism; Female; Guanosine; Hemodynamics; Hypoxanthine; Hypoxanthines; | 1995 |
Lipoamide influences substrate selection in post-ischaemic perfused rat hearts.
Topics: Acetates; Acetylation; Animals; Aspartic Acid; Binding, Competitive; Carbon Isotopes; Glutamates; Gl | 1994 |
Metabolic recovery of isolated working rat heart after brief global ischemia.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Fasting; Glucose-6-Phosphate; Glucosephospha | 1994 |
The effects of exogenous lactate and pyruvate on the recovery of coronary flow in the rat heart after ischaemia.
Topics: Animals; Coronary Circulation; Glucose; In Vitro Techniques; L-Lactate Dehydrogenase; Lactates; Lact | 1993 |
Substrate-induced changes in the lipid content of ischemic and reperfused myocardium. Its relation to hemodynamic recovery.
Topics: Animals; Disease Models, Animal; Fatty Acids; Glucose; Glycerol; Heart; Lactates; Lactic Acid; Male; | 1993 |
Transient inhibition of glucose uptake mimics ischemic preconditioning by salvaging ischemic myocardium in the rabbit heart.
Topics: Acetates; Animals; Biological Transport; Glucose; Hemodynamics; Myocardial Ischemia; Pyruvates; Pyru | 1995 |
Requirement of glycolytic substrate for metabolic recovery during moderate low flow ischemia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Glucose; Glycolysis; I | 1995 |
Inhibitory effect of pyruvate on release of glutathione and swelling of rat heart mitochondria.
Topics: Animals; Arsenicals; Biological Transport; Calcium; Depression, Chemical; Glutathione; Hypoxia; In V | 1995 |
Effects of thoracic epidural anesthesia on changes in ischemic myocardial metabolism induced by intracoronary injection of endothelin in dogs.
Topics: Adenosine Triphosphate; Anesthesia, Epidural; Animals; Coronary Circulation; Dogs; Endothelins; Fema | 1996 |
Glycogen utilization and ischemic injury in the isolated rat heart.
Topics: Animals; Creatine Kinase; Fasting; Glycogen; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Ma | 1997 |
Effects of dichloroacetate on mechanical recovery and oxidation of physiologic substrates after ischemia and reperfusion in the isolated heart.
Topics: Acetoacetates; Animals; Dichloroacetic Acid; Fatty Acids; Glucose; Heart; In Vitro Techniques; Lacta | 1998 |
Pyruvate augments mechanical function via activation of the pyruvate dehydrogenase complex in reperfused ischemic immature rabbit hearts.
Topics: Animals; Animals, Newborn; Enzyme Activation; Female; Heart; Male; Myocardial Ischemia; Myocardium; | 1998 |
Regulation of the Ca2+ gradient across the sarcoplasmic reticulum in perfused rabbit heart. A 19F nuclear magnetic resonance study.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Binding Proteins; Fluorine Radioisotopes; Ischemic | 1998 |
Glycolytic ATP production is not essential for NA(+)-K+ ATPase function and contractile recovery during postischemic reperfusion in isolated rat hearts.
Topics: Adenosine Triphosphate; Animals; Glucose; Glycogen; Glycolysis; Heart; In Vitro Techniques; Male; My | 1998 |
Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate.
Topics: Adenine Nucleotides; Animals; Capillary Permeability; Deoxyglucose; Hydrogen-Ion Concentration; In V | 1999 |
S(+)-ketamine, but not R(-)-ketamine, reduces postischemic adherence of neutrophils in the coronary system of isolated guinea pig hearts.
Topics: Anesthetics, Dissociative; Animals; Cell Adhesion; Coronary Vessels; Guinea Pigs; Humans; Ketamine; | 1999 |
The effects of mannitol, albumin, and cardioplegia enhancers on 24-h rat heart preservation.
Topics: Albumins; Animals; Blood Pressure; Coronary Vessels; Creatine Kinase; Diuretics, Osmotic; Free Radic | 1999 |
Cytosolic redox state mediates postischemic response to pyruvate dehydrogenase stimulation.
Topics: Animals; Cytosol; Heart; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardi | 1999 |
Antioxidative properties of pyruvate and protection of the ischemic rat heart during cardioplegia.
Topics: Animals; Antioxidants; Apoptosis; Cardioplegic Solutions; Electron Spin Resonance Spectroscopy; Free | 1999 |
Sevoflurane and isoflurane do not enhance the pre- and postischemic eicosanoid production in guinea pig hearts.
Topics: Anesthetics, Inhalation; Animals; Coronary Circulation; Dinoprost; Eicosanoids; Guinea Pigs; Hemodyn | 2000 |
Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state.
Topics: Animals; Antioxidants; Coumaric Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea P | 2000 |
Nucleoside transport inhibition in ischemic myocardium results in enhanced taurine efflux.
Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Hypoxanthine; Inosine; Lactates; Microdialys | 2001 |
Effects of dietary polyunsaturated fatty acids and hepatic steatosis on the functioning of isolated working rat heart under normoxic conditions and during post-ischemic reperfusion.
Topics: Adenine; Animals; Aorta; Ascorbic Acid; Body Weight; Cardiac Output; Cell Respiration; Cholesterol, | 2001 |
Monitoring of porcine myocardial ischemia and reperfusion by intravasal microdialysis.
Topics: Animals; Biomarkers; Blood Glucose; Disease Models, Animal; Female; Glutamic Acid; Glycerol; Hemodyn | 2002 |
Effects of chronic caloric restriction on mitochondrial respiration in the ischemic reperfused rat heart.
Topics: Adenosine Diphosphate; Animals; Caloric Restriction; Carboxylic Acids; Cell Respiration; Diet; Fatty | 2002 |