pyruvic acid has been researched along with Germinoblastoma in 10 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, colorectal cancer cells can effectively shift to FAO to survive both glucose restriction and increases in oxidative stress at the expense of decreasing anabolism." | 2.66 | The Role of Mitochondrial Fat Oxidation in Cancer Cell Proliferation and Survival. ( De Oliveira, MP; Liesa, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Oliveira, MP | 1 |
| Liesa, M | 1 |
| Fala, M | 1 |
| Somai, V | 1 |
| Dannhorn, A | 1 |
| Hamm, G | 1 |
| Gibson, K | 1 |
| Couturier, DL | 1 |
| Hesketh, R | 1 |
| Wright, AJ | 1 |
| Takats, Z | 1 |
| Bunch, J | 1 |
| Barry, ST | 1 |
| Goodwin, RJA | 1 |
| Brindle, KM | 5 |
| Serrao, EM | 2 |
| Kettunen, MI | 4 |
| Rodrigues, TB | 1 |
| Lewis, DY | 1 |
| Gallagher, FA | 3 |
| Hu, DE | 3 |
| Sakamoto, A | 1 |
| Kunou, S | 1 |
| Shimada, K | 1 |
| Tsunoda, M | 1 |
| Aoki, T | 1 |
| Iriyama, C | 1 |
| Tomita, A | 1 |
| Nakamura, S | 1 |
| Hayakawa, F | 1 |
| Kiyoi, H | 1 |
| Dutta, P | 1 |
| Le, A | 1 |
| Vander Jagt, DL | 1 |
| Tsukamoto, T | 1 |
| Martinez, GV | 1 |
| Dang, CV | 1 |
| Gillies, RJ | 1 |
| Schmidt, R | 1 |
| Laustsen, C | 1 |
| Dumez, JN | 1 |
| Marco-Rius, I | 1 |
| Ardenkjaer-Larsen, JH | 2 |
| Frydman, L | 1 |
| Day, SE | 2 |
| Karlsson, M | 1 |
| Gisselsson, A | 1 |
| Lerche, MH | 1 |
| ZAMFIRESCU-GHEORGHIU, M | 1 |
| PETRESCU, M | 1 |
| GROZEA, P | 1 |
| GOCIU, M | 1 |
| SIGHETEA, E | 1 |
| CIOBANU, F | 1 |
| Lerche, M | 1 |
| Wolber, J | 1 |
| Golman, K | 1 |
| O'Donnell-Tormey, J | 1 |
| Nathan, CF | 1 |
| Lanks, K | 1 |
| DeBoer, CJ | 1 |
| de la Harpe, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. A Phase I, Double Blind, Placebo Controlled, Safety Study.[NCT00332215] | Phase 1 | 70 participants (Anticipated) | Interventional | 2006-02-28 | Terminated (stopped due to Dr. Milla has left University of Minnesota. The study is no longer being conducted at this site.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvic acid and Germinoblastoma
| Article | Year |
|---|---|
The Role of Mitochondrial Fat Oxidation in Cancer Cell Proliferation and Survival.
Topics: Adipose Tissue; Animals; Cell Proliferation; Cell Survival; Fatty Acids; Glucose; Glycolysis; Humans | 2020 |
9 other studies available for pyruvic acid and Germinoblastoma
| Article | Year |
|---|---|
Comparison of
Topics: Animals; Carbon Isotopes; Lactic Acid; Lymphoma; Magnetic Resonance Imaging; Mass Spectrometry; Mice | 2021 |
Analysis of
Topics: Animals; Carbon Isotopes; Carbon Radioisotopes; Injections; Isotope Labeling; Lactic Acid; Lymphoma; | 2018 |
Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells.
Topics: Cancer-Associated Fibroblasts; Cell Survival; Citric Acid Cycle; Coculture Techniques; Energy Metabo | 2019 |
Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors.
Topics: Animals; Antimetabolites, Antineoplastic; B-Lymphocytes; Carbon Isotopes; Cell Line, Tumor; Glutamin | 2013 |
In vivo single-shot 13C spectroscopic imaging of hyperpolarized metabolites by spatiotemporal encoding.
Topics: Algorithms; Animals; Echo-Planar Imaging; Kidney; Lactic Acid; Lymphoma; Magnetic Resonance Imaging; | 2014 |
Detection of tumor glutamate metabolism in vivo using (13)C magnetic resonance spectroscopy and hyperpolarized [1-(13)C]glutamate.
Topics: Alanine Transaminase; Animals; Carbon Isotopes; Cell Survival; Disease Models, Animal; Glutamic Acid | 2011 |
[Contribution to the study of serum pyruvic acid in various malignant blood diseases].
Topics: Humans; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma | 1962 |
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carbon Isotopes; Cell Death; Cell Line, Tumor; Etoposide | 2007 |
Secretion of pyruvate. An antioxidant defense of mammalian cells.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line; Cell Survival; Connective Tissue; Fibroblasts; | 1987 |