pyruvic acid has been researched along with Galactosemias in 4 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Galactosemias: A group of inherited enzyme deficiencies which feature elevations of GALACTOSE in the blood. This condition may be associated with deficiencies of GALACTOKINASE; UDPGLUCOSE-HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; or UDPGLUCOSE 4-EPIMERASE. The classic form is caused by UDPglucose-Hexose-1-Phosphate Uridylyltransferase deficiency, and presents in infancy with FAILURE TO THRIVE; VOMITING; and INTRACRANIAL HYPERTENSION. Affected individuals also may develop MENTAL RETARDATION; JAUNDICE; hepatosplenomegaly; ovarian failure (PRIMARY OVARIAN INSUFFICIENCY); and cataracts. (From Menkes, Textbook of Child Neurology, 5th ed, pp61-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lens galactitol levels were reduced approximately 57% in 10-day galactose-fed rats treated with the ARI (tolrestat, 100 mg/kg bwt/day, 6-day pretreatment); the changes in the lower segment of glycolysis, alpha-glycerophosphate levels, redox state of NAD-couples, and energy metabolism were partially prevented while NADP+/ NADPH ratios were unchanged and galactose 1-phosphate levels were further increased." | 1.30 | Glycolytic pathway, redox state of NAD(P)-couples and energy metabolism in lens in galactose-fed rats: effect of an aldose reductase inhibitor. ( Burgan, J; Faller, A; Obrosova, I; Ostrow, E; Williamson, JR, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohanty, I | 1 |
| Joshi, S | 1 |
| Trivedi, D | 1 |
| Srivastava, S | 1 |
| Tandon, R | 1 |
| Gupta, SK | 1 |
| Obrosova, I | 1 |
| Faller, A | 1 |
| Burgan, J | 1 |
| Ostrow, E | 1 |
| Williamson, JR | 1 |
| Varma, SD | 1 |
| Devamanoharan, PS | 1 |
| Rutzen, AR | 1 |
| Ali, AH | 1 |
| Henein, M | 1 |
| Kolodny, EH | 1 |
| Yatziv, S | 1 |
4 other studies available for pyruvic acid and Galactosemias
| Article | Year |
|---|---|
Pyruvate modulates antioxidant status of cultured human lens epithelial cells under hypergalactosemic conditions.
Topics: Antioxidants; Cataract; Cells, Cultured; Epithelial Cells; Galactosemias; Glutathione; Humans; Lens | 2002 |
Glycolytic pathway, redox state of NAD(P)-couples and energy metabolism in lens in galactose-fed rats: effect of an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Energy Metabolism; Enzyme Inhibitors; Galactitol; Galactose; Galactosem | 1997 |
Attenuation of galactose-induced cataract by pyruvate.
Topics: Adenosine Triphosphate; Animals; Aqueous Humor; Cataract; Diet; Galactose; Galactosemias; Glycoprote | 1999 |
Laboratory approaches for inherited neurometabolic diseases.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Galactosemias; Homocystinuria; Humans; Lactates; Lact | 1985 |