pyruvic acid has been researched along with Fatty Liver, Nonalcoholic in 9 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone is effective in improving insulin resistance and liver histology in patients with nonalcoholic steatohepatitis (NASH)." | 3.88 | Pioglitazone improves hepatic mitochondrial function in a mouse model of nonalcoholic steatohepatitis. ( Abdo, K; Andrews, P; Bril, F; Cusi, K; Frye, RF; Garrett, TJ; Guingab, J; Jose, D; Kalavalapalli, S; Koelmel, JP; Li, WY; Sunny, NE; Yost, RA, 2018) |
| "Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in developed countries." | 1.48 | Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells. ( Blanco, GR; Cameron, K; Cartier, J; Drake, AJ; Dunn, WB; Hay, DC; Lyall, MJ; Meehan, RR; Meseguer-Ripolles, J; O'Duibhir, E; Szkolnicka, D; Thomson, JP; Villarin, BL; Wang, Y, 2018) |
| "Protection against fatty liver is partially recapitulated by the systemic administration of low-dose carboxyatractyloside, a specific inhibitor of ANT." | 1.46 | Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance. ( Cho, J; Choi, CS; Chun, SK; Han, C; Joseph, AM; Kalavalapalli, S; Kim, JS; Lee, HY; Lee, YJ; Mathews, CE; Morgan, D; Oh, SP; Park, HJ; Park, SY; Shiratsuchi, T; Someya, S; Sunny, NE; Terada, N; Wohlgemuth, SE; Zhang, Y, 2017) |
| "Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and there is great interest in understanding the potential role of alterations in mitochondrial metabolism in its pathogenesis." | 1.43 | Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by (13)C Magnetic Resonance Spectroscopy. ( Befroy, DE; Dufour, S; Petersen, KF; Rothman, DL; Shulman, GI, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, LM | 1 |
| Pitts, CB | 1 |
| Friesen-Waldner, LJ | 1 |
| Prabhu, NH | 1 |
| Mathers, KE | 1 |
| Sinclair, KJ | 1 |
| Wade, TP | 1 |
| Regnault, TRH | 1 |
| McKenzie, CA | 1 |
| Tuthill, TA | 1 |
| Ross, TT | 1 |
| Kalavalapalli, S | 2 |
| Bril, F | 1 |
| Koelmel, JP | 1 |
| Abdo, K | 1 |
| Guingab, J | 1 |
| Andrews, P | 1 |
| Li, WY | 1 |
| Jose, D | 1 |
| Yost, RA | 1 |
| Frye, RF | 1 |
| Garrett, TJ | 1 |
| Cusi, K | 1 |
| Sunny, NE | 2 |
| Lyall, MJ | 1 |
| Cartier, J | 1 |
| Thomson, JP | 1 |
| Cameron, K | 1 |
| Meseguer-Ripolles, J | 1 |
| O'Duibhir, E | 1 |
| Szkolnicka, D | 1 |
| Villarin, BL | 1 |
| Wang, Y | 1 |
| Blanco, GR | 1 |
| Dunn, WB | 1 |
| Meehan, RR | 1 |
| Hay, DC | 1 |
| Drake, AJ | 1 |
| Allen, J | 1 |
| Zhang, J | 1 |
| Quickel, MD | 1 |
| Kennett, M | 1 |
| Patterson, AD | 1 |
| Hankey-Giblin, PA | 1 |
| Lockman, KA | 1 |
| Htun, V | 1 |
| Sinha, R | 1 |
| Treskes, P | 1 |
| Nelson, LJ | 1 |
| Martin, SF | 1 |
| Rogers, SM | 1 |
| Le Bihan, T | 1 |
| Hayes, PC | 1 |
| Plevris, JN | 1 |
| Petersen, KF | 1 |
| Befroy, DE | 1 |
| Dufour, S | 1 |
| Rothman, DL | 1 |
| Shulman, GI | 1 |
| Morris, EM | 1 |
| Meers, GM | 1 |
| Koch, LG | 1 |
| Britton, SL | 1 |
| Fletcher, JA | 1 |
| Fu, X | 1 |
| Shankar, K | 1 |
| Burgess, SC | 1 |
| Ibdah, JA | 1 |
| Rector, RS | 1 |
| Thyfault, JP | 1 |
| Cho, J | 1 |
| Zhang, Y | 1 |
| Park, SY | 1 |
| Joseph, AM | 1 |
| Han, C | 1 |
| Park, HJ | 1 |
| Chun, SK | 1 |
| Morgan, D | 1 |
| Kim, JS | 1 |
| Someya, S | 1 |
| Mathews, CE | 1 |
| Lee, YJ | 1 |
| Wohlgemuth, SE | 1 |
| Lee, HY | 1 |
| Choi, CS | 1 |
| Shiratsuchi, T | 1 |
| Oh, SP | 1 |
| Terada, N | 1 |
9 other studies available for pyruvic acid and Fatty Liver, Nonalcoholic
| Article | Year |
|---|---|
In Vivo Magnetic Resonance Spectroscopy of Hyperpolarized [1-
Topics: Animals; Diet, Western; Guinea Pigs; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectrosc | 2021 |
Editorial for "In Vivo Magnetic Resonance Spectroscopy of Hyperpolarized [1-
Topics: Animals; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Diet, Western; Guinea Pigs; Mag | 2021 |
Pioglitazone improves hepatic mitochondrial function in a mouse model of nonalcoholic steatohepatitis.
Topics: Adipose Tissue; Amino Acids, Branched-Chain; Animals; Citric Acid Cycle; Diet; Female; Fructose; Hum | 2018 |
Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells.
Topics: Caprylates; Hepatocytes; Humans; Lactic Acid; Non-alcoholic Fatty Liver Disease; Pyruvic Acid; Trans | 2018 |
Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model.
Topics: Animals; Apolipoproteins E; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Collagen; Cytokines; D | 2018 |
Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Ammonia; Caprylates; Cell Line, Tumor; Cholesterol; Fatty | 2016 |
Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by (13)C Magnetic Resonance Spectroscopy.
Topics: Adult; Anthropometry; Carbon; Carbon-13 Magnetic Resonance Spectroscopy; Case-Control Studies; Gluta | 2016 |
Aerobic capacity and hepatic mitochondrial lipid oxidation alters susceptibility for chronic high-fat diet-induced hepatic steatosis.
Topics: Aerobiosis; Animals; Carnitine; Citric Acid Cycle; Diet, High-Fat; Disease Susceptibility; Fatty Aci | 2016 |
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance.
Topics: Adenine Nucleotide Translocator 2; Adenosine Triphosphate; Animals; Atractyloside; Diet, High-Fat; D | 2017 |