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pyruvic acid and Fatigue

pyruvic acid has been researched along with Fatigue in 3 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
"In a double-blind placebo-controlled crossover study of ten patients with multiple sclerosis, we found amantadine hydrochloride therapy to be effective in improving fatigability in six."9.06Amantadine, fatigue, and multiple sclerosis. ( Appenzeller, O; Rosenberg, GA, 1988)
"Propofol is a wildly used general anesthetic in clinic, and inspired by the rapid antidepressant effects induced by ketamine at non-anesthetic dose, the present study was undertaken to investigate the anti-fatigue effects and underlying mechanisms of propofol at a non-anesthetic dose in 70% hepatectomy induced POF model in rats."5.72Propofol ameliorates acute postoperative fatigue and promotes glucagon-regulated hepatic gluconeogenesis by activating CREB/PGC-1α and accelerating fatty acids beta-oxidation. ( Li, JC; Li, S; Li, Y; Mi, TY; Shen, XM; Wang, HL; Wang, LX; Xue, R; Yin, XL; Zhang, WW; Zhang, Y; Zhang, YZ, 2022)
"In a double-blind placebo-controlled crossover study of ten patients with multiple sclerosis, we found amantadine hydrochloride therapy to be effective in improving fatigability in six."5.06Amantadine, fatigue, and multiple sclerosis. ( Appenzeller, O; Rosenberg, GA, 1988)
"Propofol is a wildly used general anesthetic in clinic, and inspired by the rapid antidepressant effects induced by ketamine at non-anesthetic dose, the present study was undertaken to investigate the anti-fatigue effects and underlying mechanisms of propofol at a non-anesthetic dose in 70% hepatectomy induced POF model in rats."1.72Propofol ameliorates acute postoperative fatigue and promotes glucagon-regulated hepatic gluconeogenesis by activating CREB/PGC-1α and accelerating fatty acids beta-oxidation. ( Li, JC; Li, S; Li, Y; Mi, TY; Shen, XM; Wang, HL; Wang, LX; Xue, R; Yin, XL; Zhang, WW; Zhang, Y; Zhang, YZ, 2022)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Zhang, WW1
Xue, R1
Mi, TY1
Shen, XM1
Li, JC1
Li, S1
Zhang, Y1
Li, Y1
Wang, LX1
Yin, XL1
Wang, HL1
Zhang, YZ1
Lubek, BM1
Mainwood, GW1
Rosenberg, GA1
Appenzeller, O1

Trials

1 trial available for pyruvic acid and Fatigue

ArticleYear
Amantadine, fatigue, and multiple sclerosis.
    Archives of neurology, 1988, Volume: 45, Issue:10

    Topics: Amantadine; beta-Endorphin; beta-Lipotropin; Disability Evaluation; Fatigue; Humans; Lactates; Lacti

1988

Other Studies

2 other studies available for pyruvic acid and Fatigue

ArticleYear
Propofol ameliorates acute postoperative fatigue and promotes glucagon-regulated hepatic gluconeogenesis by activating CREB/PGC-1α and accelerating fatty acids beta-oxidation.
    Biochemical and biophysical research communications, 2022, 01-01, Volume: 586

    Topics: Acetyl Coenzyme A; Animals; Carnitine O-Palmitoyltransferase; CREB-Binding Protein; Fatigue; Fatty A

2022
Lactate and pyruvate production in isolated thiamine-deficient rat diaphragm strips.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:3

    Topics: Animals; Diaphragm; Fatigue; Glucose; Glycolysis; Hydrogen; Hypoxia; In Vitro Techniques; Lactates;

1984