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pyruvic acid and Fasting Hypoglycemia

pyruvic acid has been researched along with Fasting Hypoglycemia in 38 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Fasting Hypoglycemia: HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.

Research Excerpts

ExcerptRelevanceReference
"The activities of glycogen phosphorylase and synthase during infusions of glucagon, isoproterenol, or cyanide in isolated liver of fed rats submitted to short-term insulin-induced hypoglycemia (IIH) was investigated."3.74Liver glycogen metabolism during short-term insulin-induced hypoglycemia in fed rats. ( Bazotte, RB; Curi, R; Lopes-Bertolini, G; Obici, S, 2008)
") per day for a period of 30 days produced hypoglycemia, with associated increased urinary excretion of glucose and depletion of liver glycogen and pyruvic acid contents."3.73Prospective protective role of melatonin against arsenic-induced metabolic toxicity in Wistar rats. ( Chatterjee, AK; Pal, S, 2005)
"Moderate hypoglycemia is not life-threatening, but if experienced recurrently it may present several clinical complications."1.39Pyruvate administration reduces recurrent/moderate hypoglycemia-induced cortical neuron death in diabetic rats. ( Choi, BY; Kim, HJ; Kim, JH; Sohn, M; Song, HK; Suh, SW; Won, SJ; Yoo, JH, 2013)
"For this purpose, a condition of hyperinsulinemia/hypoglycaemia was obtained with an intraperitoneal (ip) injection of regular insulin (1."1.35Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia. ( Bazotte, RB; Curi, R; Felisberto-Junior, AM; Garcia, RF; Oliveira-Yamashita, F, 2009)
"Babesiosis was diagnosed by examination of blood smears."1.33Glucose, lactate, and pyruvate concentrations in dogs with babesiosis. ( Jacobson, LS; Lobetti, RG, 2005)
" In conclusion, this study suggests that short-term administration of LA at high dosage to normal and diabetic rats causes an inhibition of gluconeogenesis secondary to an interference with hepatic fatty acid oxidation."1.30Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats. ( Bashan, N; Gutman, A; Khamaisi, M; Potashnik, R; Rudich, A; Tritschler, HJ, 1999)
"Intrauterine growth retardation was induced in newborn dogs after 3 days of maternal nutritional deprivation (birth weight 251 +/- 7 versus 227 +/- 7 g, p less than 0."1.27Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs. ( Kliegman, RM, 1988)
"This hypoglycemia is not affected by treatment with adrenaline, glucagon, nicotinadenine dinucleotide (NAD), adenosine triphosphate (ATP) alanine (A), or pyruvate (P), while fructose (F) and dihydroxyacetone (DHA) slightly increase the plasma glucose concentration."1.27Studies on the site of the block in gluconeogenesis causing severe hypoglycemia in intestinal ischemia shock in rats. ( Snijders, PM; Valkenburg, PW; van der Meer, C, 1985)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199010 (26.32)18.7374
1990's5 (13.16)18.2507
2000's12 (31.58)29.6817
2010's10 (26.32)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Heinemann-Yerushalmi, L1
Bentovim, L1
Felsenthal, N1
Vinestock, RC1
Michaeli, N1
Krief, S1
Silberman, A1
Cohen, M1
Ben-Dor, S1
Brenner, O1
Haffner-Krausz, R1
Itkin, M1
Malitsky, S1
Erez, A1
Zelzer, E1
Travassos, PB1
Godoy, G1
De Souza, HM2
Curi, R6
Bazotte, RB6
Cotter, DG1
Ercal, B1
d'Avignon, DA1
Dietzen, DJ1
Crawford, PA1
Gauthier, N1
Wu, JW1
Wang, SP1
Allard, P1
Mamer, OA1
Sweetman, L1
Moser, AB1
Kratz, L1
Alvarez, F1
Robitaille, Y1
Lépine, F1
Mitchell, GA1
Choi, BY1
Kim, JH1
Kim, HJ1
Yoo, JH1
Song, HK1
Sohn, M1
Won, SJ1
Suh, SW2
Nam, H1
Jones, D1
Cooksey, RC1
Gao, Y1
Sink, S1
Cox, J1
McClain, DA1
Obici, S1
Lopes-Bertolini, G1
Oliveira-Yamashita, F1
Garcia, RF1
Felisberto-Junior, AM2
Helbok, R1
Schmidt, JM1
Kurtz, P1
Hanafy, KA1
Fernandez, L1
Stuart, RM1
Presciutti, M1
Ostapkovich, ND1
Connolly, ES1
Lee, K1
Badjatia, N1
Mayer, SA1
Claassen, J1
Lakshmanan, R1
Loo, JA1
Drake, T1
Leblanc, J1
Ytterberg, AJ1
McArthur, DL1
Etchepare, M1
Vespa, PM1
Geisler, SA1
Tavoni, TM1
Carrara, MA1
Amaral, AI2
Teixeira, AP1
Sonnewald, U1
Alves, PM1
Otonkoski, T1
Kaminen, N1
Ustinov, J1
Lapatto, R1
Meissner, T1
Mayatepek, E1
Kere, J1
Sipilä, I1
FRAWLEY, TF1
HO, P2
REBER, EF2
Pal, S2
Chatterjee, AK2
Dote, T1
Kono, K1
Usuda, K1
Shimizu, H1
Tanimoto, Y1
Dote, E1
Hayashi, S1
Jacobson, LS1
Lobetti, RG1
Aoyama, K1
Matsumori, Y1
Liu, J1
Swanson, RA1
Klonoff, DC1
Brunetti, P1
Bueti, A1
Antonella, MA1
Calabrese, G1
Fabietti, PG1
Santeusanio, F1
Massi Benedetti, M1
Cox, DW2
Morris, PG1
Feeney, J1
Bachelard, HS2
Ratcheson, RA1
Blank, AC1
Ferrendelli, JA1
Matsumoto, K1
Yamada, K1
Kohmura, E1
Kinoshita, A1
Hayakawa, T1
Geng, MY1
Saito, H1
Nishiyama, N1
Hodgkins, PS1
Wu, HQ1
Zielke, HR1
Schwarcz, R1
Khamaisi, M1
Rudich, A1
Potashnik, R1
Tritschler, HJ1
Gutman, A1
Bashan, N1
Ekberg, K1
Fernqvist-Forbes, E1
Nair, S1
de L Costello, AM1
Pal, DK1
Manandhar, DS1
Rajbhandari, S1
Land, JM1
Patel, N1
Vardanega-Peicher, M2
Lopes, G1
Lima, FB1
Nakano, LC1
Borba-Murad, GR1
Ceddia, RB1
Kauppinen, RA1
Nicholls, DG1
Yao, H1
Sadoshima, S1
Nishimura, Y1
Fujii, K1
Oshima, M1
Ishitsuka, T1
Fujishima, M1
Kliegman, RM1
Garofalo, O1
van der Meer, C1
Valkenburg, PW1
Snijders, PM1

Reviews

1 review available for pyruvic acid and Fasting Hypoglycemia

ArticleYear
Effects of hypoglycaemia on neuronal metabolism in the adult brain: role of alternative substrates to glucose.
    Journal of inherited metabolic disease, 2013, Volume: 36, Issue:4

    Topics: Brain; Energy Metabolism; Glucose; Humans; Hypoglycemia; Neurons; Pyruvic Acid

2013

Other Studies

37 other studies available for pyruvic acid and Fasting Hypoglycemia

ArticleYear
BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development.
    Developmental cell, 2021, 04-19, Volume: 56, Issue:8

    Topics: Animals; Animals, Newborn; Citric Acid Cycle; Embryo Loss; Embryonic Development; Gene Deletion; Hyp

2021
Performance during a strenuous swimming session is associated with high blood lactate: pyruvate ratio and hypoglycemia in fasted rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018, Mar-26, Volume: 51, Issue:5

    Topics: Animals; Blood Glucose; Fasting; Hypoglycemia; Lactic Acid; Liver; Male; Perfusion; Physical Conditi

2018
Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth.
    The Journal of biological chemistry, 2013, Jul-05, Volume: 288, Issue:27

    Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Citric Acid Cycle; Coenzyme A-Transferases; Female

2013
A liver-specific defect of Acyl-CoA degradation produces hyperammonemia, hypoglycemia and a distinct hepatic Acyl-CoA pattern.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carbon Dioxide; Gene Knockout Techniques; Gene Order; G

2013
Pyruvate administration reduces recurrent/moderate hypoglycemia-induced cortical neuron death in diabetic rats.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Cell Death; Cerebral Cortex; Dendrites; Diabetes Mellitus, Experimental; Diabetes Mellitus,

2013
Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver.
    Diabetes, 2016, Volume: 65, Issue:6

    Topics: Animals; Gluconeogenesis; Glucose; Hypoglycemia; Hypoxia; Iron; Iron Deficiencies; Liver; Male; Mice

2016
Liver glycogen metabolism during short-term insulin-induced hypoglycemia in fed rats.
    Cell biochemistry and function, 2008, Volume: 26, Issue:7

    Topics: Animals; Enzyme Activation; Feeding Behavior; Glucagon; Glucose; Glycogen Phosphorylase; Glycogen Sy

2008
Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.
    Cell biochemistry and function, 2009, Volume: 27, Issue:1

    Topics: Alanine; Animals; Fasting; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hyperinsulinism; Hypoglyce

2009
Systemic glucose and brain energy metabolism after subarachnoid hemorrhage.
    Neurocritical care, 2010, Volume: 12, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Brain; Critical Care; Energy Metaboli

2010
Metabolic crisis after traumatic brain injury is associated with a novel microdialysis proteome.
    Neurocritical care, 2010, Volume: 12, Issue:3

    Topics: Blood Glucose; Brain; Brain Injuries; Brain Ischemia; Cerebral Hemorrhage, Traumatic; Energy Metabol

2010
Participation of the liver gluconeogenesis in the glibenclamide-induced hypoglycaemia in rats.
    Cell biochemistry and function, 2011, Volume: 29, Issue:2

    Topics: Animals; Gluconeogenesis; Glucose; Glyburide; Humans; Hypoglycemia; Lactic Acid; Liver; Male; Pyruvi

2011
Estimation of intracellular fluxes in cerebellar neurons after hypoglycemia: importance of the pyruvate recycling pathway and glutamine oxidation.
    Journal of neuroscience research, 2011, Volume: 89, Issue:5

    Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Glucose; Glutamic Acid; Glutamine; Glycolysi

2011
Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release.
    Diabetes, 2003, Volume: 52, Issue:1

    Topics: Adult; Biological Transport; Exercise; Exercise Test; Female; Fibroblasts; Genes, Dominant; Humans;

2003
The role of the adrenal cortex in glucose and pyruvic acid metabolism in man including the use of intravenous hydrocortisone in acute hypoglycemia.
    Annals of the New York Academy of Sciences, 1955, May-27, Volume: 61, Issue:2

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Glucose; Humans; Hydrocortisone; Hypoglycemia; Pyruvates; P

1955
The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes.
    The Cornell veterinarian, 1957, Volume: 47, Issue:1

    Topics: Acidosis; Animals; Female; Hypoglycemia; Keto Acids; Ketone Bodies; Ketones; Ketosis; Oxaloacetic Ac

1957
The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes.
    The Cornell veterinarian, 1957, Volume: 47, Issue:1

    Topics: Acidosis; Animals; Female; Hypoglycemia; Keto Acids; Ketone Bodies; Ketones; Ketosis; Oxaloacetic Ac

1957
The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes.
    The Cornell veterinarian, 1957, Volume: 47, Issue:1

    Topics: Acidosis; Animals; Female; Hypoglycemia; Keto Acids; Ketone Bodies; Ketones; Ketosis; Oxaloacetic Ac

1957
The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes.
    The Cornell veterinarian, 1957, Volume: 47, Issue:1

    Topics: Acidosis; Animals; Female; Hypoglycemia; Keto Acids; Ketone Bodies; Ketones; Ketosis; Oxaloacetic Ac

1957
Protective effect of methionine supplementation on arsenic-induced alteration of glucose homeostasis.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2004, Volume: 42, Issue:5

    Topics: Alanine Transaminase; Amino Acids; Animals; Arsenic Poisoning; Arsenites; Aspartate Aminotransferase

2004
Prospective protective role of melatonin against arsenic-induced metabolic toxicity in Wistar rats.
    Toxicology, 2005, Mar-01, Volume: 208, Issue:1

    Topics: Alanine Transaminase; Animals; Antioxidants; Arsenites; Aspartate Aminotransferases; Blood Glucose;

2005
Systemic effects and skin injury after experimental dermal exposure to monochloroacetic acid.
    Toxicology and industrial health, 2003, Volume: 19, Issue:7-10

    Topics: Accidents, Occupational; Acetates; Acidosis, Lactic; Animals; Blood Chemical Analysis; Burns, Chemic

2003
Glucose, lactate, and pyruvate concentrations in dogs with babesiosis.
    American journal of veterinary research, 2005, Volume: 66, Issue:2

    Topics: Acid-Base Equilibrium; Animals; Babesiosis; Blood Gas Analysis; Blood Glucose; Blood Pressure Determ

2005
Pyruvate administered after severe hypoglycemia reduces neuronal death and cognitive impairment.
    Diabetes, 2005, Volume: 54, Issue:5

    Topics: Animals; Cell Death; Cognition Disorders; Disease Models, Animal; Hypoglycemia; Insulin; Ketoglutari

2005
Pyruvate therapy for severe hypoglycemia.
    Diabetes technology & therapeutics, 2005, Volume: 7, Issue:4

    Topics: Humans; Hypoglycemia; Pyruvic Acid

2005
Metabolic effects of intensified insulin therapy.
    Experimental and clinical endocrinology, 1984, Volume: 83, Issue:2

    Topics: Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Fatty Acids, Nonest

1984
31P-n.m.r. studies on cerebral energy metabolism under conditions of hypoglycaemia and hypoxia in vitro.
    The Biochemical journal, 1983, May-15, Volume: 212, Issue:2

    Topics: Animals; Brain; Energy Metabolism; Glucose; Guinea Pigs; Hypoglycemia; In Vitro Techniques; Magnetic

1983
Regionally selective metabolic effects of hypoglycemia in brain.
    Journal of neurochemistry, 1981, Volume: 36, Issue:6

    Topics: Adenosine Triphosphate; Animals; Brain; Electroencephalography; Fructosediphosphates; Glucose; Gluco

1981
Role of pyruvate in ischaemia-like conditions on cultured neurons.
    Neurological research, 1994, Volume: 16, Issue:6

    Topics: Animals; Brain Ischemia; Cell Hypoxia; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Do

1994
Protective effects of pyridoxal phosphate against glucose deprivation-induced damage in cultured hippocampal neurons.
    Journal of neurochemistry, 1997, Volume: 68, Issue:6

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Cells, Cultured; Energy Metabolism; Glucose; Glutamic

1997
2-Oxoacids regulate kynurenic acid production in the rat brain: studies in vitro and in vivo.
    Journal of neurochemistry, 1999, Volume: 72, Issue:2

    Topics: 2-Aminoadipic Acid; Animals; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Excitatory Amino Aci

1999
Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental;

1999
Brain substrate utilisation during acute hypoglycaemia.
    Diabetologia, 1999, Volume: 42, Issue:7

    Topics: Acute Disease; Adult; Amino Acids; Blood Glucose; Brain; Glucose Clamp Technique; Humans; Hypoglycem

1999
Neonatal hypoglycaemia in Nepal 2. Availability of alternative fuels.
    Archives of disease in childhood. Fetal and neonatal edition, 2000, Volume: 82, Issue:1

    Topics: Age Factors; Blood Glucose; Cross-Sectional Studies; Energy Metabolism; Fatty Acids, Nonesterified;

2000
Time sequence of changes in the responsiveness of glycogen breakdown to adrenergic agonists in perfused liver of rats with insulin-induced hypoglycemia.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2000, Volume: 33, Issue:7

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Bucladesine; Glucose; Glycolysis; Hypo

2000
Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2001, Volume: 34, Issue:6

    Topics: Alanine; Animals; Blood Glucose; Cryoprotective Agents; Gluconeogenesis; Glucose; Glutamine; Glycero

2001
Synaptosomal bioenergetics. The role of glycolysis, pyruvate oxidation and responses to hypoglycaemia.
    European journal of biochemistry, 1986, Jul-01, Volume: 158, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arsenic; Arsenites; Biological Transport; En

1986
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
    Journal of neurology, neurosurgery, and psychiatry, 1989, Volume: 52, Issue:3

    Topics: Brain Damage, Chronic; Diabetes Mellitus; Diabetic Coma; Diabetic Neuropathies; Female; Humans; Hypo

1989
Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs.
    Pediatric research, 1988, Volume: 24, Issue:5

    Topics: Adenosine Triphosphate; Animals; Dogs; Energy Metabolism; Female; Fetal Growth Retardation; Glycogen

1988
Brain levels of NADH and NAD+ under hypoxic and hypoglycaemic conditions in vitro.
    Journal of neurochemistry, 1988, Volume: 51, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain; Female; Glucose; Guinea Pigs; Hypoglycemia; Hypoxia, Brain;

1988
Studies on the site of the block in gluconeogenesis causing severe hypoglycemia in intestinal ischemia shock in rats.
    Circulatory shock, 1985, Volume: 16, Issue:2

    Topics: Adenosine Triphosphate; Alanine; Animals; Epinephrine; Female; Glucagon; Gluconeogenesis; Hypoglycem

1985