pyruvic acid has been researched along with Experimental Hepatoma in 20 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Follow-up screening was performed in hepatocellular carcinoma with a focused CRISPR library targeting imaging-related genes." | 1.56 | Functional Genetic Screening Enables Theranostic Molecular Imaging in Cancer. ( Ackerman, D; Gade, TPF; Johnson, O; Mercadante, M; Perkons, NR; Pilla, G; Profka, E, 2020) |
| "These data indicated that AS-30D hepatoma cells had a predominantly oxidative and not a glycolytic type of metabolism." | 1.31 | Substrate oxidation and ATP supply in AS-30D hepatoma cells. ( Moreno-Sánchez, R; Rodríguez-Enríquez, S; Torres-Márquez, ME, 2000) |
| "Viable tissue slices from rat liver and Morris hepatoma 3924A were compared as to their ability to incorporate carbons from [U-14 C]pyruvate into newly synthesized cholesterol versus CO2." | 1.27 | Continuous pyruvate carbon flux to newly synthesized cholesterol and the suppressed evolution of pyruvate-generated CO2 in tumors: further evidence for a persistent truncated Krebs cycle in hepatomas. ( Coleman, PS; Parlo, RA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (55.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perkons, NR | 1 |
| Johnson, O | 1 |
| Pilla, G | 1 |
| Profka, E | 1 |
| Mercadante, M | 1 |
| Ackerman, D | 1 |
| Gade, TPF | 1 |
| Cipolleschi, MG | 2 |
| Marzi, I | 1 |
| Santini, R | 1 |
| Fredducci, D | 1 |
| Vinci, MC | 1 |
| D'Amico, M | 1 |
| Rovida, E | 1 |
| Stivarou, T | 1 |
| Torre, E | 1 |
| Dello Sbarba, P | 1 |
| Stecca, B | 1 |
| Olivotto, M | 2 |
| von Morze, C | 1 |
| Larson, PE | 1 |
| Hu, S | 1 |
| Yoshihara, HA | 1 |
| Bok, RA | 1 |
| Goga, A | 1 |
| Ardenkjaer-Larsen, JH | 1 |
| Vigneron, DB | 1 |
| MURAMATSU, M | 1 |
| Coleman, PS | 2 |
| Lavietes, BB | 1 |
| Mapes, JP | 1 |
| Aultman, KS | 1 |
| Paradies, G | 1 |
| Capuano, F | 1 |
| Palombini, G | 1 |
| Galeotti, T | 1 |
| Papa, S | 1 |
| de Alaniz, MJ | 1 |
| de Gómez Dumm, IN | 1 |
| Brenner, RR | 1 |
| Caldini, R | 1 |
| Chevanne, M | 1 |
| López-Gómez, FJ | 1 |
| Torres-Márquez, ME | 2 |
| Moreno-Sánchez, R | 2 |
| Rosella, G | 1 |
| Zajac, JD | 1 |
| Kaczmarczyk, SJ | 1 |
| Andrikopoulos, S | 1 |
| Proietto, J | 1 |
| Dietzen, DJ | 1 |
| Davis, EJ | 1 |
| Martinus, RD | 1 |
| Garth, GP | 1 |
| Webster, TL | 1 |
| Cartwright, P | 1 |
| Naylor, DJ | 1 |
| Høj, PB | 1 |
| Hoogenraad, NJ | 1 |
| Rodríguez-Enríquez, S | 1 |
| Xie, Z | 1 |
| Li, H | 1 |
| Liu, L | 1 |
| Kahn, BB | 1 |
| Najjar, SM | 1 |
| Shah, W | 1 |
| Matsuno, T | 2 |
| Parlo, RA | 1 |
| Kelleher, JK | 1 |
| Bryan, BM | 1 |
| Mallet, RT | 1 |
| Holleran, AL | 1 |
| Murphy, AN | 1 |
| Fiskum, G | 1 |
| Arora, KK | 1 |
| Smith, R | 1 |
| Williams, JF | 1 |
1 review available for pyruvic acid and Experimental Hepatoma
| Article | Year |
|---|---|
Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Biological Transport, Active; Cell Division; Cell Memb | 1981 |
19 other studies available for pyruvic acid and Experimental Hepatoma
| Article | Year |
|---|---|
Functional Genetic Screening Enables Theranostic Molecular Imaging in Cancer.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Carcinoma, Hepatocellular; CRISPR-Cas Systems; D | 2020 |
Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Citric Ac | 2014 |
Investigating tumor perfusion and metabolism using multiple hyperpolarized (13)C compounds: HP001, pyruvate and urea.
Topics: Animals; Carbon Isotopes; Contrast Media; Cyclopropanes; Disease Models, Animal; Imaging, Three-Dime | 2012 |
Studies on the pyruvate metabolism during hepatocarcinogenesis: in vivo metabolism of pyruvate-2-C14 in the liver of 3'-Me-DAB fed rats.
Topics: Animals; Liver Neoplasms, Experimental; Pyruvates; Pyruvic Acid; Rats | 1961 |
Effectors of fatty acid synthesis in hepatoma tissue culture cells.
Topics: Ammonium Chloride; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Fatty Acids; Glucose; Glutamin | 1982 |
Transport of pyruvate in mitochondria from different tumor cells.
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Kinetics; Liver N | 1983 |
Effect of different carbon sources on delta 5 desaturation activity of HTC cells.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Carbon Radioisotopes; Cel | 1982 |
The respiration-linked limiting step of tumor cell transition from the non-cycling to the cycling state: its inhibition by oxidizable substrates and its relationships to purine metabolism.
Topics: Adenine; Animals; Antimycin A; Folic Acid; Glycolysis; Interphase; Liver Neoplasms, Experimental; Ox | 1983 |
Control of oxidative phosphorylation in AS-30D hepatoma mitochondria.
Topics: Adenine Nucleotides; Animals; Glutamates; Glutamic Acid; Liver Neoplasms, Experimental; Magnesium; M | 1993 |
Impaired suppression of gluconeogenesis induced by overexpression of a noninsulin-responsive phosphoenolpyruvate carboxykinase gene.
Topics: Animals; Base Sequence; Enzyme Induction; Fructose-Bisphosphatase; Gluconeogenesis; Glucosephosphate | 1993 |
Oxidation of pyruvate, malate, citrate, and cytosolic reducing equivalents by AS-30D hepatoma mitochondria.
Topics: Aconitate Hydratase; Animals; Citrates; Citric Acid; Citric Acid Cycle; Cytosol; Electrochemistry; F | 1993 |
Selective induction of mitochondrial chaperones in response to loss of the mitochondrial genome.
Topics: Animals; Blotting, Western; Cell Nucleus; Clone Cells; Cytosol; DNA, Mitochondrial; DNA, Neoplasm; E | 1996 |
Substrate oxidation and ATP supply in AS-30D hepatoma cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Ce | 2000 |
Metabolic regulation of Na(+)/P(i)-cotransporter-1 gene expression in H4IIE cells.
Topics: Adenoviridae; Androstadienes; Animals; Antibiotics, Antineoplastic; Blotting, Northern; Carrier Prot | 2000 |
End products of glutamine oxidation in MC-29 virus-induced chicken hepatoma mitochondria.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Chickens; Citric Acid Cycle; Glutamates; Glutam | 1989 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Li | 1989 |
Continuous pyruvate carbon flux to newly synthesized cholesterol and the suppressed evolution of pyruvate-generated CO2 in tumors: further evidence for a persistent truncated Krebs cycle in hepatomas.
Topics: Animals; Benzene Derivatives; Carbon; Carbon Dioxide; Carbon Radioisotopes; Cholesterol; Citrates; C | 1986 |
Analysis of tricarboxylic acid-cycle metabolism of hepatoma cells by comparison of 14CO2 ratios.
Topics: Animals; Aspartic Acid; Carbon Dioxide; Carbon Radioisotopes; Chromatography, Ion Exchange; Citric A | 1987 |
"Pyruvate recycling" and its influence on the estimation of the pentose pathway in intact liver and Morris hepatoma 5123TC cells.
Topics: Animals; Carbon Radioisotopes; Dicarboxylic Acids; Dihydroxyacetone Phosphate; Female; Glucose; Gluc | 1987 |