pyruvic acid has been researched along with Endotoxemia in 15 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We tested the hypothesis that reduced caloric intake during endotoxemia, as an experimental model for sepsis, further reduces arginine availability." | 7.76 | Reduced caloric intake during endotoxemia reduces arginine availability and metabolism. ( Bruins, MJ; Deutz, NE; Luiking, YC; Poeze, M, 2010) |
| "To investigate whether the vasopressin analog terlipressin might induce hepatosplanchnic ischemia during long-term, hyperdynamic, volume-resuscitated porcine endotoxemia." | 7.73 | Low-dose terlipressin during long-term hyperdynamic porcine endotoxemia: effects on hepatosplanchnic perfusion, oxygen exchange, and metabolism. ( Albicini, M; Asfar, P; Bracht, H; Brückner, UB; Ehrmann, U; Hauser, B; Iványi, Z; Kick, J; Radermacher, P; Vogt, J; Wachter, U, 2005) |
| "To compare the effects of a 12 h continuous infusion of iloprost, a stable prostacyclin analogue, on hepatic blood flow (Qliv), O2 exchange, and energy metabolism during a 24 h hyperdynamic, porcine endotoxemia with volume resuscitation alone." | 7.70 | Hepatic O2 exchange and liver energy metabolism in hyperdynamic porcine endotoxemia: effects of iloprost. ( Altherr, J; Brinkmann, A; Georgieff, M; Jauch, KW; Matejovic, M; Radermacher, P; Träger, K; Vlatten, A; Vogt, J; Wachter, U; Zülke, C, 2000) |
| "To investigate markers of splanchnic perfusion and the extent of endotoxemia during cardiopulmonary bypass (CPB) and to compare the effects of dopamine and milrinone on both splanchnic perfusion and endotoxemia." | 5.09 | Markers of splanchnic perfusion and intestinal translocation of endotoxins during cardiopulmonary bypass: effects of dopamine and milrinone. ( Andersen, LW; Baek, L; Doolan, L; Liu, G; McNicol, L, 1999) |
| "We tested the hypothesis that reduced caloric intake during endotoxemia, as an experimental model for sepsis, further reduces arginine availability." | 3.76 | Reduced caloric intake during endotoxemia reduces arginine availability and metabolism. ( Bruins, MJ; Deutz, NE; Luiking, YC; Poeze, M, 2010) |
| "To investigate whether the vasopressin analog terlipressin might induce hepatosplanchnic ischemia during long-term, hyperdynamic, volume-resuscitated porcine endotoxemia." | 3.73 | Low-dose terlipressin during long-term hyperdynamic porcine endotoxemia: effects on hepatosplanchnic perfusion, oxygen exchange, and metabolism. ( Albicini, M; Asfar, P; Bracht, H; Brückner, UB; Ehrmann, U; Hauser, B; Iványi, Z; Kick, J; Radermacher, P; Vogt, J; Wachter, U, 2005) |
| " We analyzed effects of a colloid infusion during endotoxemia on intestinal perfusion, and on the metabolites lactate, pyruvate, glucose, and glycerol in the intestinal wall, the latter by a microdialysis technique." | 3.71 | Hypovolemia is a main factor behind disturbed perfusion and metabolism in the intestine during endotoxemia in cat. ( Grände, PO; Holbeck, S, 2002) |
| "To compare the effects of a 12 h continuous infusion of iloprost, a stable prostacyclin analogue, on hepatic blood flow (Qliv), O2 exchange, and energy metabolism during a 24 h hyperdynamic, porcine endotoxemia with volume resuscitation alone." | 3.70 | Hepatic O2 exchange and liver energy metabolism in hyperdynamic porcine endotoxemia: effects of iloprost. ( Altherr, J; Brinkmann, A; Georgieff, M; Jauch, KW; Matejovic, M; Radermacher, P; Träger, K; Vlatten, A; Vogt, J; Wachter, U; Zülke, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Effenberger-Neidnicht, K | 1 |
| Brauckmann, S | 1 |
| Jägers, J | 1 |
| Patyk, V | 1 |
| Waack, IN | 1 |
| Kirsch, M | 1 |
| Hamburger, T | 1 |
| Broecker-Preuss, M | 1 |
| Hartmann, M | 1 |
| Schade, FU | 1 |
| de Groot, H | 1 |
| Petrat, F | 1 |
| Poeze, M | 1 |
| Bruins, MJ | 1 |
| Luiking, YC | 1 |
| Deutz, NE | 1 |
| Wellhoener, P | 1 |
| Vietheer, A | 1 |
| Sayk, F | 1 |
| Schaaf, B | 1 |
| Lehnert, H | 1 |
| Dodt, C | 1 |
| Holbeck, S | 1 |
| Grände, PO | 2 |
| Bäckström, T | 1 |
| Liska, J | 1 |
| Oldner, A | 1 |
| Lockowandt, U | 1 |
| Franco-Cereceda, A | 1 |
| Asfar, P | 1 |
| Hauser, B | 1 |
| Iványi, Z | 1 |
| Ehrmann, U | 1 |
| Kick, J | 1 |
| Albicini, M | 1 |
| Vogt, J | 3 |
| Wachter, U | 3 |
| Brückner, UB | 2 |
| Radermacher, P | 4 |
| Bracht, H | 1 |
| Chew, MS | 1 |
| Johansson, A | 1 |
| Anderson, C | 1 |
| Ersson, A | 1 |
| Tønnesen, E | 1 |
| Leclercq, P | 1 |
| Filippi, C | 1 |
| Sibille, B | 1 |
| Hamant, S | 1 |
| Keriel, C | 1 |
| Leverve, XM | 1 |
| McNicol, L | 1 |
| Andersen, LW | 1 |
| Liu, G | 1 |
| Doolan, L | 1 |
| Baek, L | 1 |
| Takeuchi, K | 1 |
| del Nido, PJ | 1 |
| Ibrahim, AE | 1 |
| Poutias, DN | 1 |
| Glynn, P | 1 |
| Cao-Danh, H | 1 |
| Cowan, DB | 1 |
| McGowan, FX | 1 |
| Träger, K | 3 |
| Matejovic, M | 3 |
| Zülke, C | 2 |
| Vlatten, A | 2 |
| Altherr, J | 2 |
| Brinkmann, A | 2 |
| Jauch, KW | 2 |
| Georgieff, M | 3 |
| Möller, AD | 1 |
| Tugtekin, IF | 1 |
| Theisen, M | 1 |
| Stehr, A | 1 |
| Ploner, F | 1 |
| Matura, K | 1 |
| Ince, C | 1 |
2 trials available for pyruvic acid and Endotoxemia
| Article | Year |
|---|---|
Metabolic alterations in adipose tissue during the early phase of experimental endotoxemia in humans.
Topics: Adult; Biomarkers; Double-Blind Method; Endotoxemia; Glycerol; Glycolysis; Humans; Injections, Intra | 2011 |
Markers of splanchnic perfusion and intestinal translocation of endotoxins during cardiopulmonary bypass: effects of dopamine and milrinone.
Topics: Adult; Aged; Biological Transport; Cardiopulmonary Bypass; Dopamine; Endotoxemia; Endotoxins; Humans | 1999 |
13 other studies available for pyruvic acid and Endotoxemia
| Article | Year |
|---|---|
Protective Effects of Sodium Pyruvate during Systemic Inflammation Limited to the Correction of Metabolic Acidosis.
Topics: Acidosis; Animals; Blood Chemical Analysis; Blood Pressure; Endotoxemia; Inflammation; Lipopolysacch | 2019 |
Effects of glycine, pyruvate, resveratrol, and nitrite on tissue injury and cytokine response in endotoxemic rats.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cytokines; Disease Models, Animal; Drug Therapy, Combin | 2013 |
Reduced caloric intake during endotoxemia reduces arginine availability and metabolism.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Endotoxins; Energy Intake; Escherichia coli; | 2010 |
Hypovolemia is a main factor behind disturbed perfusion and metabolism in the intestine during endotoxemia in cat.
Topics: Albumins; Animals; Cats; Colloids; Dextrans; Endotoxemia; Fluid Therapy; Glucose; Glycerol; Hemodyna | 2002 |
Splanchnic metabolism during gut ischemia and short-term endotoxin and hemorrhagic shock as evaluated by intravasal microdialysis.
Topics: Abdomen; Animals; Endotoxemia; Endotoxins; Glucose; Glycerol; Hemodynamics; Ileum; Ischemia; Lactic | 2004 |
Low-dose terlipressin during long-term hyperdynamic porcine endotoxemia: effects on hepatosplanchnic perfusion, oxygen exchange, and metabolism.
Topics: Animals; Blood Pressure; Cardiac Output; Endotoxemia; Endotoxins; Escherichia coli; Female; Glucose; | 2005 |
Decreases in myocardial glucose and increases in pyruvate but not ischaemia are observed during porcine endotoxaemia.
Topics: Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Endotoxemia; Glucose; Lactic Acid; M | 2008 |
Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats.
Topics: Adenine Nucleotides; Animals; Caprylates; Cell Membrane Permeability; Cells, Cultured; Dihydroxyacet | 1997 |
Increased myocardial calcium cycling and reduced myofilament calcium sensitivity in early endotoxemia.
Topics: Actin Cytoskeleton; Adenosine Triphosphate; Animals; Calcium; Dobutamine; Endotoxemia; Energy Metabo | 1999 |
Hepatic O2 exchange and liver energy metabolism in hyperdynamic porcine endotoxemia: effects of iloprost.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxemia; Ener | 2000 |
Beneficial effects of low-dose prostacyclin on cat intestinal perfusion during endotoxemia as evaluated with microdialysis and oxygen transport variables.
Topics: Animals; Antihypertensive Agents; Blood Gas Analysis; Cats; Constriction, Pathologic; Disease Models | 2001 |
Hepatic oxygen exchange and energy metabolism in hyperdynamic porcine endotoxemia: effects of the combined thromboxane receptor antagonist and synthase inhibitor DTTX30.
Topics: Animals; Blood Gas Analysis; Blood Glucose; Chlorobenzenes; Disease Models, Animal; Drug Evaluation, | 2001 |
Increased ileal-mucosal-arterial PCO2 gap is associated with impaired villus microcirculation in endotoxic pigs.
Topics: Animals; Blood Gas Analysis; Carbon Dioxide; Disease Models, Animal; Endotoxemia; Escherichia coli I | 2001 |