Page last updated: 2024-10-20

pyruvic acid and Diabetes Mellitus

pyruvic acid has been researched along with Diabetes Mellitus in 84 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
" This association is suggestive of the MIDD syndrome and the demonstration of metabolic abnormalities (raised serum lactic acid, abnormal lactate/pyruvate ratio) was compatible with a mitochondrial disease."3.74[Dilated cardiomyopathy, diabetes and deafness related to a mutation of mitochondrial DNA]. ( Charbonnier, B; Ferreira-Maldent, N; Guilmot, JL; Maillot, F; Quilliet, L, 2007)
"By central venous catheterization, 6 control persons, 7 patients with liver cirrhosis and 6 patients with diabetes mellitus were infused for 48 h with a 20% (w/v) mixture of glucose/xylitol (1:1)."3.66[Carbohydrate infusion in internal diseases. A comparative study in metabolically healthy, liver diseased and diabetic patients. VI. Infusions of a glucose/xylitol mixture (1:1 ratio) over a 48-hour period]. ( Egberts, EH; Horbach, L; Malchow, H; Müller, PH; Prestele, H; Rittershofer, H; Schmülling, R, 1982)
"Accordingly, recent studies on cancer and diabetes have identified protein-protein interactions, post-translational processes, and transcriptional factors that modulate MPC function."2.66Mitochondrial Pyruvate Carrier Function in Health and Disease across the Lifespan. ( Buchanan, JL; Taylor, EB, 2020)
"Systems metabolomics analysis of these cancers identified pyruvate carboxylation as an essential metabolic hub that feeds carbon skeletons of downstream metabolites of oxaloacetate into the biosynthesis of various cellular components including membrane lipids, nucleotides, amino acids, and the redox control."2.58Roles of pyruvate carboxylase in human diseases: from diabetes to cancers and infection. ( Attwood, PV; Jitrapakdee, S; Lao-On, U, 2018)

Research

Studies (84)

TimeframeStudies, this research(%)All Research%
pre-199059 (70.24)18.7374
1990's2 (2.38)18.2507
2000's10 (11.90)29.6817
2010's10 (11.90)24.3611
2020's3 (3.57)2.80

Authors

AuthorsStudies
Li, J1
Yang, Y1
Peng, Z1
Yang, J1
Li, Y1
Haythorne, E1
Lloyd, M1
Walsby-Tickle, J1
Tarasov, AI1
Sandbrink, J1
Portillo, I1
Exposito, RT1
Sachse, G1
Cyranka, M1
Rohm, M1
Rorsman, P1
McCullagh, J1
Ashcroft, FM1
Buchanan, JL1
Taylor, EB1
Lao-On, U1
Attwood, PV1
Jitrapakdee, S1
González-Lao, E1
Corte, Z1
Simón, M1
Ricós, C1
Coskun, A1
Braga, F1
Aarsand, AK1
Carobene, A1
Bartlett, WA1
Boned, B1
Asland, B1
Díaz-Garzón, J1
Marqués-García, F1
Minchinela, J1
Perich, C1
Fernández-Calle, P1
Roraas, T1
Fernández-Fernández, P1
Jonker, N1
Sandberg, S1
Abdurrachim, D1
Teo, XQ1
Woo, CC1
Ong, SY1
Salleh, NF1
Lalic, J1
Tan, RS1
Lee, PTH1
Adeva-Andany, M1
López-Ojén, M1
Funcasta-Calderón, R1
Ameneiros-Rodríguez, E1
Donapetry-García, C1
Vila-Altesor, M1
Rodríguez-Seijas, J1
Schindler, CE1
Partap, U1
Patchen, BK1
Swoap, SJ1
Luo, X1
Li, R1
Yan, LJ1
Inoue, T1
Murakami, N1
Ayabe, T1
Oto, Y1
Nishino, I1
Goto, Y2
Koga, Y1
Sakuta, R1
von Lewinski, D1
Rainer, PP1
Gasser, R1
Huber, MS1
Khafaga, M1
Wilhelm, B1
Haas, T1
Mächler, H1
Rössl, U1
Pieske, B1
HIMWICH, WA1
HIMWICH, HE1
ROOT, HF1
STOTZ, E1
CARPENTER, TM1
Jelen, S1
Wacker, S1
Aponte-Santamaría, C1
Skott, M1
Rojek, A1
Johanson, U1
Kjellbom, P1
Nielsen, S1
de Groot, BL1
Rützler, M1
Shimizu, I1
Ishikawa, E1
Fukuda, T1
Okazaki, S1
Totani, M1
Ren, J1
GUGGENHEIM, K1
MAYER, J1
PANSINI, R3
FERSINI, C4
MONTENERO, P1
BOLDRINI, R1
FOSTER, JM1
VILLEE, CA1
JORKE, D1
GASTALDI, F1
MAGGI, G2
GITELSON, S1
SHRIFTER, N2
KRITZER, MD1
CATTANEO, R2
PELOCCHINO, AM2
PESCETTI, G1
FEDELI, S1
PRINOTTI, C1
BOERO, P1
SAN LORENZO, G1
BUTTERFIELD, WJ1
THOMPSON, RH1
BIANCHESSI, M1
FACCHINI, G1
MORATTI, F1
ORLANDI, G1
MIGDALSKA, B1
MASSALSKI, W1
ANDERSON, J4
MARKS, V2
SMITH, MJ1
SAVAGE, N2
GILLMAN, J2
GILBERT, C2
TAKANAMI, A1
OHYA, S1
BERSELLI, L1
DE PALMA, C1
DI SALVO, C3
RIPA, R1
MAZZA, R2
DE MEUTTER, RC1
SHREEVE, WW2
GARLAND, PB1
RANDLE, PJ1
NEWSHOLME, EA1
BENTLEY, R2
MOORHOUSE, JA1
PICCARDO, MG1
LUZIETTI, L1
CAPURSO, L1
DEPASQUALE, C1
DIMASSIMO, S1
DELLAMORE, M1
DEMEUTTER, RC1
MORIKAMI, S1
APPANNA, TC1
COMTY, CM1
LOPRESTI, T1
LANDAU, BR1
HASTINGS, AB1
NESBETT, FB1
POLOSA, P1
Maechler, P1
GILLILAND, IC1
MARTIN, MM1
OSBORN, MJ1
CHAIKOFF, IL1
FELTS, JM1
LICHTENBELT, HV1
FLORIJN, E1
LESTRADET, H1
AMATUZIO, DS1
STUTZMAN, FL1
NESBITT, S1
Rudic, RD1
Curtis, AM1
Cheng, Y1
FitzGerald, G1
Ferreira-Maldent, N1
Maillot, F1
Quilliet, L1
Guilmot, JL1
Charbonnier, B1
HORWITT, MK1
HILLS, OW1
KREISLER, O1
PEARSON, OH1
HSIEH, CK1
Avogaro, A1
Duner, E1
Marescotti, C1
Ferrara, D1
Del Prato, S1
Nosadini, R2
Tiengo, A1
Noy, GA1
Nattrass, M2
Alberti, KG2
Johnston, DG1
Home, PD1
Orskov, H1
Liebich, HM1
Pickert, A1
Wöll, J1
Passariello, N1
Fici, F1
Giugliano, D1
Ceriello, A1
Dello Russo, P1
Sgambato, S1
Sheppard, MC1
Burrin, J1
Egberts, EH1
Rittershofer, H1
Müller, PH1
Schmülling, R1
Prestele, H1
Horbach, L1
Malchow, H1
Szutowicz, A1
Tomaszewicz, M1
Bielarczyk, H1
Zhao, W1
Devamanoharan, PS1
Varma, SD1
Iizuka, K1
Nakajima, H1
Ono, A1
Okita, K1
Miyazaki, Ji1
Miyagawa, Ji1
Namba, M1
Hanafusa, T1
Matsuzawa, Y1
Thornalley, PJ1
Jahan, I1
Ng, R1
Hamarat Baysal, S1
Uslan, AH1
Kr'stev, I1
Panaiotov, Ch1
Penev, M1
Runev, N1
Tsoncheva, A1
Misheva, A1
Munnich, A1
Rustin, P1
Rötig, A1
Chretien, D1
Bonnefont, JP1
Nuttin, C1
Cormier, V1
Vassault, A1
Parvy, P1
Bardet, J1
Yao, H1
Sadoshima, S1
Nishimura, Y1
Fujii, K1
Oshima, M1
Ishitsuka, T1
Fujishima, M1
Kawiak, W1
Stelmasiak, Z1
Nowicki, J1
Hasiec, T1
Gieracz-Nazar, A1
Wróblewski, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Controlled Trial for People With Established Type 2 Diabetes During Ramadan: Canagliflozin (Invokana™) vs. Standard Dual Therapy Regimen: The 'Can Do Ramadan' Study[NCT02694263]Phase 425 participants (Actual)Interventional2016-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for pyruvic acid and Diabetes Mellitus

ArticleYear
Mitochondrial Pyruvate Carrier Function in Health and Disease across the Lifespan.
    Biomolecules, 2020, 08-08, Volume: 10, Issue:8

    Topics: Aging; Animals; Diabetes Mellitus; Humans; Mitochondrial Membrane Transport Proteins; Monocarboxylic

2020
Roles of pyruvate carboxylase in human diseases: from diabetes to cancers and infection.
    Journal of molecular medicine (Berlin, Germany), 2018, Volume: 96, Issue:3-4

    Topics: Animals; Diabetes Mellitus; Humans; Infections; Neoplasms; Pyruvate Carboxylase; Pyruvic Acid

2018
Systematic review of the biological variation data for diabetes related analytes.
    Clinica chimica acta; international journal of clinical chemistry, 2019, Volume: 488

    Topics: Adiponectin; Blood Glucose; C-Peptide; Diabetes Mellitus; Fructosamine; Glycated Hemoglobin; Humans;

2019
Comprehensive review on lactate metabolism in human health.
    Mitochondrion, 2014, Volume: 17

    Topics: Alanine; Carbon Dioxide; Diabetes Mellitus; Glucose; Humans; Lactic Acid; Metabolic Networks and Pat

2014
Roles of Pyruvate, NADH, and Mitochondrial Complex I in Redox Balance and Imbalance in β Cell Function and Dysfunction.
    Journal of diabetes research, 2015, Volume: 2015

    Topics: Animals; Blood Glucose; Diabetes Mellitus; Electron Transport Complex I; Glucose; Humans; Insulin; I

2015
[Lactate . pyruvate].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 8

    Topics: Acidosis, Lactic; Biomarkers; Diabetes Mellitus; Humans; Lactic Acid; Neoplasms; Pyruvic Acid

2002
Novel regulation of insulin secretion: the role of mitochondria.
    Current opinion in investigational drugs (London, England : 2000), 2003, Volume: 4, Issue:10

    Topics: Adenosine Triphosphate; Animals; Calcium; Diabetes Mellitus; DNA, Mitochondrial; Electron Transport;

2003
Key role of acetyl-CoA in cytoplasm of nerve terminals in disturbances of acetylcholine metabolism in brain.
    Folia neuropathologica, 1997, Volume: 35, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcholine; Aluminum; Animals; Brain; Brain Diseases; C

1997

Other Studies

76 other studies available for pyruvic acid and Diabetes Mellitus

ArticleYear
A novel photoelectrochemical microfluidic chip for multi-index determination of diabetes and its complications.
    Biosensors & bioelectronics, 2022, Dec-01, Volume: 217

    Topics: 3-Hydroxybutyric Acid; Acidosis, Lactic; Biomarkers; Biosensing Techniques; Diabetes Mellitus; Diabe

2022
Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.
    Nature communications, 2022, 11-14, Volume: 13, Issue:1

    Topics: Diabetes Mellitus; Glucose; Glycolysis; Humans; Hyperglycemia; Insulin; Islets of Langerhans; Mechan

2022
Cardiac metabolic modulation upon low-carbohydrate low-protein ketogenic diet in diabetic rats studied in vivo using hyperpolarized
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:4

    Topics: Acetoacetates; Animals; Blood Glucose; Butyrates; Carbon-13 Magnetic Resonance Spectroscopy; Cardiot

2019
Chronic rapamycin treatment causes diabetes in male mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Aug-15, Volume: 307, Issue:4

    Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus; Estradiol; Estrogen Replacement The

2014
Pyruvate Improved Insulin Secretion Status in a Mitochondrial Diabetes Mellitus Patient.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:5

    Topics: Adult; C-Peptide; Diabetes Mellitus; Humans; Insulin; Male; Mitochondrial Diseases; Mutation; Pyruvi

2016
Glucose-transporter-mediated positive inotropic effects in human myocardium of diabetic and nondiabetic patients.
    Metabolism: clinical and experimental, 2010, Volume: 59, Issue:7

    Topics: Aged; Cardiotonic Agents; Diabetes Mellitus; Female; Glucose; Glucose Transport Proteins, Facilitati

2010
Pyruvic acid in exercising depancreatized dogs and diabetic patients.
    The Journal of biological chemistry, 1946, Volume: 165, Issue:2

    Topics: Animals; Carbohydrate Metabolism; Carbohydrates; Diabetes Mellitus; Dogs; Humans; Pancreas; Pyruvic

1946
The respiratory quotient and blood pyruvate and lactate responses after oral ingestion of glucose and fructose in diabetes mellitus with and without insulin.
    The American journal of the medical sciences, 1946, Volume: 211

    Topics: Diabetes Mellitus; Diet; Fructose; Glucose; Humans; Insulin; Lactates; Lactic Acid; Pyruvates; Pyruv

1946
Aquaporin-9 protein is the primary route of hepatocyte glycerol uptake for glycerol gluconeogenesis in mice.
    The Journal of biological chemistry, 2011, Dec-30, Volume: 286, Issue:52

    Topics: Animals; Aquaporins; CHO Cells; Cricetinae; Cricetulus; Cryoprotective Agents; Diabetes Mellitus; Gl

2011
[Blood glucose, urinary glucose, blood ketone bodies, urine ketone bodies, blood lactic acid, and blood pyruvic acid].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 3

    Topics: Blood Glucose; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Glycosuria; Humans; Ketone Bodies;

2012
Paradoxical effects of pyruvate on cardiac contractile function under normal and high glucose in ventricular myocytes.
    Pharmacological research, 2003, Volume: 48, Issue:1

    Topics: Analysis of Variance; Animals; Cells, Cultured; Diabetes Mellitus; Disease Models, Animal; Glucose;

2003
Studies of pyruvate and acetate metabolism in the hereditary obesity-diabetes syndrome of mice.
    The Journal of biological chemistry, 1952, Volume: 198, Issue:1

    Topics: Acetates; Animals; Diabetes Mellitus; Mice; Obesity; Pyruvates; Pyruvic Acid; Syndrome

1952
PYRUVATE metabolism in diabetes and liver cirrhosis.
    Nutrition reviews, 1953, Volume: 11, Issue:4

    Topics: Diabetes Mellitus; Humans; Liver Cirrhosis; Pyruvates; Pyruvic Acid

1953
[The metabolic effect of small doses of ethyl alcohol in human diabetes mellitus. IV. Variations in the arterial and venous blood pyruvic acid levels].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:4

    Topics: Arteries; Blood; Diabetes Mellitus; Ethanol; Humans; Pyruvates; Pyruvic Acid

1953
[Arterial and venous blood pyruvic acid after glucose load, in the light of the phenomenon of the spontaneous variability of the blood pyruvic acid in diabetics].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:4

    Topics: Blood; Catabolite Repression; Diabetes Mellitus; Glucose; Humans; Pyruvates; Pyruvic Acid

1953
[Study of simultaneous curves of glucose pyruvic acid and lactic acid in blood after second intravenous administration of glucose in normal and diabetic subjects].
    Minerva medica, 1953, Nov-10, Volume: 44, Issue:90

    Topics: Administration, Intravenous; Blood; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Lact

1953
[Behavior of pyruvic acid in arterial and venous blood after administration of glucose in relation to the phenomenon of spontaneous changes of blood pyruvic acid in diabetes].
    Il Progresso medico, 1953, Dec-31, Volume: 9, Issue:24

    Topics: Arteries; Blood; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Pyruvates; Pyruvic Acid

1953
Pyruvate and acetate metabolism in the isolated rat diaphragm.
    The Journal of biological chemistry, 1954, Volume: 211, Issue:2

    Topics: Abdominal Muscles; Acetates; Animals; Diabetes Mellitus; Diaphragm; Pyruvates; Pyruvic Acid; Rats

1954
[The reaction of the pyruvic acid blood level after a galactose test in diabetic liver disease].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1955, May-01, Volume: 10, Issue:9

    Topics: Blood; Diabetes Complications; Diabetes Mellitus; Galactose; Liver Diseases; Pyruvates; Pyruvic Acid

1955
[Effect of glucose tolerance test in various levels on pyruvic acid in blood in normal subjects and diabetics].
    Rassegna di fisiopatologia clinica e terapeutica, 1955, Volume: 27, Issue:2

    Topics: Blood; Diabetes Mellitus; Glucose Tolerance Test; Humans; Pyruvates; Pyruvic Acid

1955
The blood pyruvic acid level in patients with stress hyperglycaemia and diabetes mellitus.
    Acta endocrinologica, 1956, Volume: 22, Issue:1

    Topics: Blood; Diabetes Mellitus; Humans; Hyperglycemia; Pyruvates; Pyruvic Acid

1956
Carbohydrate metabolism. II. Changes in the serum pyruvic acid during glucose-tolerance test in normals, diabetics, and prediabetic women.
    A.M.A. archives of internal medicine, 1956, Volume: 98, Issue:1

    Topics: Blood; Carbohydrate Metabolism; Diabetes Mellitus; Female; Glucose; Glucose Tolerance Test; Humans;

1956
[Various metabolic aspects of diabetes; pyruvic acid, electrophoretic picture of proteins and lipoproteins, blood lipase].
    Archivio per le scienze mediche, 1957, Volume: 103, Issue:1

    Topics: Diabetes Mellitus; Electrophoresis; Humans; Lipase; Lipoproteins; Pyruvates; Pyruvic Acid

1957
[Behavior of blood level of pyruvic acid, alpha-keto-glutaric & citric acid after treatment with butylsulfamidurea (BSU)].
    Archivio per le scienze mediche, 1957, Volume: 103, Issue:5

    Topics: Citrates; Citric Acid; Diabetes Mellitus; Glutarates; Humans; Keto Acids; Ketones; Pyruvates; Pyruvi

1957
[Changes of certain metabolic aspects (pyruvic acid, lactic acid, ketone bodies, lipids) in diabetics treated with hypoglycemic sulfonamides].
    Minerva medica, 1957, Jul-07, Volume: 48, Issue:54

    Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Ketone Bodies; Lactic Acid; Lipids; Pyruvates; Pyruv

1957
The effect of dimercaprol (BAL) on blood sugar and pyruvate levels in diabetes mellitus.
    Clinical science, 1957, Volume: 16, Issue:4

    Topics: Blood Glucose; Diabetes Mellitus; Dimercaprol; Humans; Pyruvates; Pyruvic Acid

1957
Estimation of blood pyruvic acid in liver diseases and in pancreatic diabetes.
    Clinica chimica acta; international journal of clinical chemistry, 1958, Volume: 3, Issue:2

    Topics: Diabetes Mellitus; Humans; Ketone Bodies; Liver Diseases; Pancreas; Pyruvates; Pyruvic Acid; Vascula

1958
[Research on the blood pyruvic acid and lactic acid levels in diabetics treated with carbutamide and tolbutamide].
    Endocrinologia e scienza della costituzione, 1958, Volume: 25, Issue:1

    Topics: Carbutamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Lactic Acid; Pyruvates; Pyruvic Acid; R

1958
[Determination of blood pyruvic acid levels after cortisone administration as a test of adrenal cortex function in diabetics].
    Endocrinologia e scienza della costituzione, 1958, Volume: 25, Issue:1

    Topics: Adrenal Cortex; Cortisone; Diabetes Mellitus; Pyruvates; Pyruvic Acid

1958
[Pyruvic acid in blood. I. Blood pyruvic acid levels following ingestion of glucose in persons with normal carbohydrate metabolism & in diabetic patients].
    Polski tygodnik lekarski, 1959, Jan-26, Volume: 14, Issue:4

    Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Eating; Glucose; Humans; Pyruvates; Pyruv

1959
Urinary excretion of pyruvate in diabetic patients.
    Lancet (London, England), 1961, Jun-17, Volume: 1, Issue:7190

    Topics: Diabetes Mellitus; Humans; Pyruvates; Pyruvic Acid

1961
Increased synthesis of phospholipid fatty acid from 2-14C sodium pyruvate in the diabetic baboon (Papio ursinus).
    The South African journal of medical sciences, 1960, Volume: 25

    Topics: Animals; Diabetes Mellitus; Fatty Acids; Papio; Papio hamadryas; Papio ursinus; Phospholipids; Pyruv

1960
Unimpaired synthesis of cholesterol from 2-14C sodium pyruvate in diabetic baboons (Papio ursinus).
    The South African journal of medical sciences, 1960, Volume: 25

    Topics: Animals; Biochemical Phenomena; Cholesterol; Diabetes Mellitus; Lipid Metabolism; Papio; Papio ursin

1960
Urinary excretion of pyruvic acid, citric acid and alpha-ketoglutaric acid after the intravenous injection of pyruvate and fructose in diabetic patients.
    The Tohoku journal of experimental medicine, 1960, Sep-25, Volume: 72

    Topics: Body Fluids; Citrates; Citric Acid; Diabetes Mellitus; Fructose; Humans; Injections, Intravenous; Ke

1960
[Blood pyruvate curve after oral glucose loading in senile diabetes].
    Giornale di gerontologia, 1959, Volume: 7

    Topics: Aged; Aged, 80 and over; Aging; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Pyruvates; Pyruv

1959
[Behavior of blood sugar, blood pyruvate and blood lactic acid after oral glucose loading in 30 elderly diabetics].
    Giornale di gerontologia, 1959, Volume: 7

    Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus; Glucose Tolerance Test; Humans; Lactates;

1959
[Behavior of the blood sugar, blood pyruvate and blood lactic acid after insulin loading in a group of 10 elderly diabetics].
    Giornale di gerontologia, 1959, Volume: 7

    Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus; Glucose Tolerance Test; Humans; Insulin;

1959
Pyruvate in diabetes mellitus concentrations in urine and blood.
    Lancet (London, England), 1962, Jun-02, Volume: 1, Issue:7240

    Topics: Diabetes Mellitus; Humans; Pyruvates; Pyruvic Acid

1962
[The pyruvate-ethanol changes after loading with cocarboxylase in diabetics].
    L' Arcispedale S. Anna di Ferrara, 1962, Volume: 15

    Topics: Diabetes Mellitus; Ethanol; Humans; Pyruvates; Pyruvic Acid; Thiamine Pyrophosphate

1962
Pyruvate and lactate excretion in patients with diabetes mellitus and benign glycosuria.
    Lancet (London, England), 1963, Aug-10, Volume: 2, Issue:7302

    Topics: Diabetes Mellitus; Glycosuria; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid

1963
Conversion of DL-lactate-2-C14 or -3-C14 or pyruvate-2-C14 to blood glucose in humans: effects of diabetes, insulin, tolbutamide, and glucose load.
    The Journal of clinical investigation, 1963, Volume: 42

    Topics: Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Lactates; Lactic Acid; Pyruvates; Pyruvi

1963
CITRATE AS AN INTERMEDIARY IN THE INHIBITION OF PHOSPHOFRUCTOKINASE IN RAT HEART MUSCLE BY FATTY ACIDS, KETONE BODIES, PYRUVATE, DIABETES, AND STARVATION.
    Nature, 1963, Oct-12, Volume: 200

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Citrates; Citric Acid; Diabetes Mellitus; Fatty Acids;

1963
[BEHAVIOR OF PYRUVIC ACID BLOOD LEVEL AND URINARY ELIMINATION IN VARIOUS FORMS OF DIABETES MELLITUS].
    Archivio "E. Maragliano" di patologia e clinica, 1963, Volume: 19

    Topics: Anti-Infective Agents, Local; Blood Chemical Analysis; Body Fluids; Diabetes Mellitus; Pyruvates; Py

1963
PYRUVATE-TOLERANCE TESTS IN HEALTHY AND DIABETIC SUBJECTS.
    Lancet (London, England), 1964, Mar-28, Volume: 1, Issue:7335

    Topics: Blood Chemical Analysis; Diabetes Mellitus; Fasting; Geriatrics; Humans; Hypoglycemic Agents; Inject

1964
[VARIOUS ASPECTS OF KETOACIDURIA AND KETOACIDEMIA IN DIABETICS: URINARY EXCRETION AND HEMATIC LEVELS OF ALPHA-KETOISOCAPROIC ACID, ALPHA-KETOISOVALERIC ACID, PYRUVIC ACID AND ALPHA-KETOGLUTARIC ACID].
    Il Policlinico. Sezione medica, 1963, Volume: 70

    Topics: Biomedical Research; Blood Chemical Analysis; Diabetes Mellitus; Hemiterpenes; Humans; Keto Acids; K

1963
[ON THE BEHAVIOR OF PYRUVIC ACID AND ALPHA-KETOGLUTARIC ACID IN PANCREATIC DIABETES. CHANGES AFTER GLUCIDE AND INSULIN LOADING].
    Il Progresso medico, 1963, Oct-31, Volume: 19

    Topics: Blood Chemical Analysis; Carbohydrate Metabolism; Diabetes Mellitus; Glucose Tolerance Test; Humans;

1963
PATHWAYS OF CARBOHYDRATE FORMATION IN MAN. III. DISTRIBUTION LABELING OF BLOOD GLUCOSE BY DL-LACTATE-2-14C OR PYRUVATE-2-14C IN DIABETIC AND NONDIABETIC SUBJECTS.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Blood; Blood Glucose; Carbohydrate Metabolism; Carbon Isotopes; Diabetes Mellitus; Drug Therapy; Glu

1964
[(CLINICAL INVESTIGATIONS ON THE METABOLISM OF KETONE BODY AND PYRUVIC ACID IN PATIENTS WITH VARIOUS ENDOCRINE DISORDERS. 1. BLOOD KETONE BODY AND PYRUVIC ACID IN PATIENTS WITH DIABETES MELLITUS.)].
    Naika hokan. Japanese archives of internal medicine, 1964, Volume: 11

    Topics: Blood Chemical Analysis; Diabetes Mellitus; Endocrine System Diseases; Geriatrics; Hematologic Disea

1964
BLOOD PYRUVIC ACID RESPONSE TO ORAL ADMINISTRATION OF GLUCOSE IN NORMAL AND DISEASED SUBJECTS.
    The Indian journal of medical research, 1964, Volume: 52

    Topics: Administration, Oral; Biomedical Research; Blood; Carbohydrate Metabolism; Diabetes Mellitus; Glucos

1964
URINARY PYRUVATE EXCRETION IN NORMAL AND DIABETIC SUBJECTS.
    Lancet (London, England), 1964, Nov-21, Volume: 2, Issue:7369

    Topics: Blood Chemical Analysis; Diabetes Mellitus; Fluids and Secretions; Insulin; Metabolism; Pyruvates; P

1964
[METABOLISM OF PYRUVIC ACID AND ITS RELATIONS WITH INSULIN THERAPY OF VARIOUS FORMS OF DIABETES MELLITUS].
    Archivio "E. Maragliano" di patologia e clinica, 1964, Volume: 20

    Topics: Blood; Diabetes Mellitus; Drug Therapy; Glucose Tolerance Test; Humans; Insulin; Metabolism; Obesity

1964
Origin of glucose and glycogen carbons formed from C14-labeled pyruvate by livers of normal and diabetic rats.
    The Journal of biological chemistry, 1955, Volume: 214, Issue:2

    Topics: Animals; Carbohydrate Metabolism; Carbon; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucos

1955
[Behavior of blood sugar, blood pyruvate and blood lactic acid after oral sulfanylurea loading in 34 diabetics].
    Giornale di gerontologia, 1959, Volume: 7

    Topics: Blood Glucose; Diabetes Mellitus; Humans; Hypoglycemic Agents; Lactates; Lactic Acid; Pyruvates; Pyr

1959
Raised blood pyruvic acid level in diabetic acidosis; the value of cocarboxylase in treatment.
    British medical journal, 1951, Jan-06, Volume: 1, Issue:4696

    Topics: Diabetes Mellitus; Diabetic Ketoacidosis; Pyruvic Acid; Thiamine Pyrophosphate

1951
Insulin and the fate of pyruvate in the diabetic liver.
    The Journal of biological chemistry, 1951, Volume: 193, Issue:2

    Topics: Diabetes Mellitus; Humans; Insulin; Liver; Pyruvates; Pyruvic Acid

1951
Pyruvate content of blood and phosphorylation of thiamine in diabetic coma.
    Biochimica et biophysica acta, 1952, Volume: 8, Issue:3

    Topics: Biochemical Phenomena; Diabetes Mellitus; Diabetic Coma; Humans; Phosphorylation; Pyruvates; Pyruvic

1952
[Pyruvic acid metabolism in diabetes].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1951, Nov-26, Volume: 27, Issue:87

    Topics: Biochemical Phenomena; Diabetes Mellitus; Humans; Pyruvates; Pyruvic Acid

1951
Blood pyruvic acid response to intravenous glucose or insulin in the normal and in patients with liver disease and with diabetes mellitus.
    The Journal of clinical investigation, 1952, Volume: 31, Issue:8

    Topics: Diabetes Mellitus; Glucose; Humans; Insulin; Liver Diseases; Pyruvates; Pyruvic Acid

1952
Peripheral clocks and the regulation of cardiovascular and metabolic function.
    Methods in enzymology, 2005, Volume: 393

    Topics: Animals; Aorta, Thoracic; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors;

2005
[Dilated cardiomyopathy, diabetes and deafness related to a mutation of mitochondrial DNA].
    Archives des maladies du coeur et des vaisseaux, 2007, Volume: 100, Issue:2

    Topics: Cardiomyopathy, Dilated; Deafness; Diabetes Mellitus; DNA, Mitochondrial; Female; Humans; Lactic Aci

2007
Lactic and pyruvic acids in the blood after glucose and exercise in diabetes mellitus.
    The American journal of physiology, 1949, Volume: 156, Issue:1

    Topics: Blood; Diabetes Mellitus; Glucose; Humans; Pyruvic Acid

1949
Metabolism of cardiac muscle; utilization of C14 labeled pyruvate and acetate in diabetic rat heart and diaphragm.
    The American journal of physiology, 1949, Volume: 158, Issue:2

    Topics: Acetates; Animals; Diabetes Mellitus; Diaphragm; Heart; Myocardium; Pyruvates; Pyruvic Acid; Radiois

1949
Metabolic effects of moderate alcohol intake with meals in insulin-dependent diabetics controlled by artificial endocrine pancreas (AEP) and in normal subjects.
    Metabolism: clinical and experimental, 1983, Volume: 32, Issue:5

    Topics: Adult; Alanine; Alcohol Drinking; Blood Glucose; Diabetes Mellitus; Diet; Ethanol; Fatty Acids, None

1983
The metabolic and hormonal response to acute normoglycaemia in type 1 (insulin-dependent) diabetes: studies with a glucose controlled insulin infusion system (artificial endocrine pancreas).
    Diabetologia, 1982, Volume: 23, Issue:3

    Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucagon; Glyc

1982
Analysis of the oxocarboxylic acid fraction in serum and urine as O-methyloximes by thermionic specific detection.
    Journal of chromatography, 1981, Nov-06, Volume: 217

    Topics: Chromatography, Gas; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Keto Acids; Pyruvates; Pyruvi

1981
Effects of pyridoxine alpha-ketoglutarate on blood glucose and lactate in type I and II diabetics.
    International journal of clinical pharmacology, therapy, and toxicology, 1983, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Female; Hemoglobin A; Humans; Lactates; Lactic

1983
The effect of diet on intermediary metabolite concentrations in Type 2 (non-insulin-dependent) diabetes mellitus.
    Diabetologia, 1983, Volume: 24, Issue:5

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Alanine; Diabetes Mellitus; Female; Glycerol; Humans; Hydroxybut

1983
[Carbohydrate infusion in internal diseases. A comparative study in metabolically healthy, liver diseased and diabetic patients. VI. Infusions of a glucose/xylitol mixture (1:1 ratio) over a 48-hour period].
    Infusionstherapie und klinische Ernahrung, 1982, Volume: 9, Issue:2

    Topics: Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Glucose Solution, Hypertonic;

1982
Fructose-mediated damage to lens alpha-crystallin: prevention by pyruvate.
    Biochimica et biophysica acta, 2000, Feb-21, Volume: 1500, Issue:2

    Topics: Animals; Antioxidants; Catalase; Cataract; Cattle; Crystallins; Diabetes Complications; Diabetes Mel

2000
Stable overexpression of the glucose-6-phosphatase catalytic subunit attenuates glucose sensitivity of insulin secretion from a mouse pancreatic beta-cell line.
    The Journal of endocrinology, 2000, Volume: 164, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Cytoplasm; Diabetes Mellitus; Fructose; Glucose

2000
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
    Journal of biochemistry, 2001, Volume: 129, Issue:4

    Topics: Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Glucose; Glycolysis; Humans;

2001
Encapsulation of PEG-urease/PEG-AlaDH enzyme system in erythrocyte.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2001, Volume: 29, Issue:5

    Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Ammonia; Diabetes Mellitus; Drug Compoun

2001
[Intermediate substrates in different stages of compensation of diabetes mellitus].
    Vutreshni bolesti, 2001, Volume: 33, Issue:1

    Topics: Blood Glucose; Cholesterol; Diabetes Complications; Diabetes Mellitus; Humans; Lipids; Lipoproteins;

2001
Clinical aspects of mitochondrial disorders.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:4

    Topics: Child, Preschool; Coma; Diabetes Mellitus; DNA, Mitochondrial; Dwarfism; Female; Heart Diseases; Hum

1992
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
    Journal of neurology, neurosurgery, and psychiatry, 1989, Volume: 52, Issue:3

    Topics: Brain Damage, Chronic; Diabetes Mellitus; Diabetic Coma; Diabetic Neuropathies; Female; Humans; Hypo

1989
[Glucose, lactic acid and pyruvic acid levels of the blood and cerebrospinal fluid in patients with diabetes mellitus and cerebral infarction].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1987, Jul-15, Volume: 40, Issue:14

    Topics: Aged; Blood Glucose; Cerebral Infarction; Diabetes Mellitus; Female; Glucose; Humans; Lactates; Lact

1987