pyruvic acid has been researched along with Compensatory Hyperinsulinemia in 9 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protection against fatty liver is partially recapitulated by the systemic administration of low-dose carboxyatractyloside, a specific inhibitor of ANT." | 1.46 | Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance. ( Cho, J; Choi, CS; Chun, SK; Han, C; Joseph, AM; Kalavalapalli, S; Kim, JS; Lee, HY; Lee, YJ; Mathews, CE; Morgan, D; Oh, SP; Park, HJ; Park, SY; Shiratsuchi, T; Someya, S; Sunny, NE; Terada, N; Wohlgemuth, SE; Zhang, Y, 2017) |
| "For this purpose, a condition of hyperinsulinemia/hypoglycaemia was obtained with an intraperitoneal (ip) injection of regular insulin (1." | 1.35 | Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia. ( Bazotte, RB; Curi, R; Felisberto-Junior, AM; Garcia, RF; Oliveira-Yamashita, F, 2009) |
| "The principal response to hyperinsulinemia was a decrease in the recycling of OAA to lactate, because there was no significant change in the conversion of OAA to PEP." | 1.29 | Response of phosphoenolpyruvate cycle activity to fasting and to hyperinsulinemia in human subjects. ( Baba, H; Chinkes, D; Rosenblatt, J; Wolfe, RR; Zhang, XJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faarkrog Høyer, K | 1 |
| Laustsen, C | 1 |
| Ringgaard, S | 1 |
| Qi, H | 1 |
| Mariager, CØ | 1 |
| Nielsen, TS | 1 |
| Sundekilde, UK | 1 |
| Treebak, JT | 1 |
| Jessen, N | 1 |
| Stødkilde-Jørgensen, H | 1 |
| Cho, J | 1 |
| Zhang, Y | 1 |
| Park, SY | 1 |
| Joseph, AM | 1 |
| Han, C | 1 |
| Park, HJ | 1 |
| Kalavalapalli, S | 1 |
| Chun, SK | 1 |
| Morgan, D | 1 |
| Kim, JS | 1 |
| Someya, S | 1 |
| Mathews, CE | 1 |
| Lee, YJ | 1 |
| Wohlgemuth, SE | 1 |
| Sunny, NE | 1 |
| Lee, HY | 1 |
| Choi, CS | 1 |
| Shiratsuchi, T | 1 |
| Oh, SP | 1 |
| Terada, N | 1 |
| Oliveira-Yamashita, F | 1 |
| Garcia, RF | 1 |
| Felisberto-Junior, AM | 1 |
| Curi, R | 1 |
| Bazotte, RB | 1 |
| Pullen, TJ | 1 |
| Sylow, L | 1 |
| Sun, G | 1 |
| Halestrap, AP | 1 |
| Richter, EA | 1 |
| Rutter, GA | 1 |
| Otonkoski, T | 1 |
| Kaminen, N | 1 |
| Ustinov, J | 1 |
| Lapatto, R | 1 |
| Meissner, T | 1 |
| Mayatepek, E | 1 |
| Kere, J | 1 |
| Sipilä, I | 1 |
| Gonsolin, D | 1 |
| Couturier, K | 1 |
| Garait, B | 1 |
| Rondel, S | 1 |
| Novel-Chaté, V | 1 |
| Peltier, S | 1 |
| Faure, P | 1 |
| Gachon, P | 1 |
| Boirie, Y | 1 |
| Keriel, C | 1 |
| Favier, R | 1 |
| Pepe, S | 1 |
| Demaison, L | 1 |
| Leverve, X | 1 |
| Wolfe, RR | 1 |
| Chinkes, D | 1 |
| Baba, H | 1 |
| Rosenblatt, J | 1 |
| Zhang, XJ | 1 |
| de L Costello, AM | 1 |
| Pal, DK | 1 |
| Manandhar, DS | 1 |
| Rajbhandari, S | 1 |
| Land, JM | 1 |
| Patel, N | 1 |
| Dhananjaya Naidu, M | 1 |
| Ravindran, K | 1 |
| Swami, KS | 1 |
9 other studies available for pyruvic acid and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
Assessment of mouse liver [1-13C]pyruvate metabolism by dynamic hyperpolarized MRS.
Topics: Animals; Blood Glucose; Carbon Isotopes; Fasting; Gluconeogenesis; Glucose Clamp Technique; Hyperins | 2019 |
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance.
Topics: Adenine Nucleotide Translocator 2; Adenosine Triphosphate; Animals; Atractyloside; Diet, High-Fat; D | 2017 |
Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.
Topics: Alanine; Animals; Fasting; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hyperinsulinism; Hypoglyce | 2009 |
Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic β-cells leads to relative hyperinsulinism during exercise.
Topics: Animals; Blood Glucose; Doxycycline; Female; Hyperinsulinism; Insulin; Insulin Secretion; Insulin-Se | 2012 |
Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release.
Topics: Adult; Biological Transport; Exercise; Exercise Test; Female; Fibroblasts; Genes, Dominant; Humans; | 2003 |
High dietary sucrose triggers hyperinsulinemia, increases myocardial beta-oxidation, reduces glycolytic flux and delays post-ischemic contractile recovery.
Topics: Animals; Blood Glucose; Body Weight; Dietary Sucrose; Glycolysis; Hyperinsulinism; In Vitro Techniqu | 2007 |
Response of phosphoenolpyruvate cycle activity to fasting and to hyperinsulinemia in human subjects.
Topics: Fasting; Humans; Hyperinsulinism; Lactic Acid; Male; Models, Biological; Oxaloacetates; Phosphoenolp | 1996 |
Neonatal hypoglycaemia in Nepal 2. Availability of alternative fuels.
Topics: Age Factors; Blood Glucose; Cross-Sectional Studies; Energy Metabolism; Fatty Acids, Nonesterified; | 2000 |
Acute and chronic effects of insulin on lactate dehydrogenase (LDH) activity in tissues of albino rat (Wistar strain).
Topics: Animals; Hyperinsulinism; Insulin; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Pyruvates; | 1988 |