pyruvic acid has been researched along with Colorectal Neoplasms in 8 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Liquid nitrogen storage can stop the metabolic process of glucose and choline phospholipid in colorectal cancer tissue samples in vitro, thus maintaining the metabolic state of tissue samples in vivo as much as possible." | 4.12 | Pretreatment optimization of tissue metabolomics in colorectal cancer. ( Deng, P; Han, Y; Huang, H; Jiang, H; Liang, H; Liu, H; Lu, CD; Peng, J; Wang, L; Wang, Y; Yang, G, 2022) |
| "We found that the earliest stages of colorectal cancer (CRC) initiation are marked by a glycolytic metabolic signature, including downregulation of the mitochondrial pyruvate carrier (MPC), which couples glycolysis and glucose oxidation through mitochondrial pyruvate import." | 1.56 | Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier. ( Bensard, CL; Berg, JA; Bott, AJ; Cluntun, A; Dove, KK; Ducker, GS; Earl, CS; Evason, KJ; Fogarty, S; Krah, NM; Lettlova, S; Murtaugh, LC; Namnath, DF; Nowinski, SM; Olson, KA; Panic, V; Rutter, J; Schell, JC; Tanner, JM; Tantin, D; Thummel, CS; Vázquez-Arreguín, K; Villanueva, CJ; Wei, P; Wisidagama, DR, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 6 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, CY | 1 |
| Pai, YC | 1 |
| Yu, LC | 1 |
| Liu, H | 1 |
| Wang, Y | 1 |
| Han, Y | 1 |
| Yang, G | 1 |
| Wang, L | 1 |
| Peng, J | 1 |
| Lu, CD | 1 |
| Deng, P | 1 |
| Liang, H | 1 |
| Huang, H | 1 |
| Jiang, H | 1 |
| Brezmes, J | 1 |
| Llambrich, M | 1 |
| Cumeras, R | 1 |
| Gumà, J | 1 |
| Yun, Z | 1 |
| Guo, Z | 1 |
| Li, X | 1 |
| Shen, Y | 1 |
| Nan, M | 1 |
| Dong, Q | 1 |
| Hou, L | 1 |
| Bensard, CL | 1 |
| Wisidagama, DR | 1 |
| Olson, KA | 1 |
| Berg, JA | 1 |
| Krah, NM | 1 |
| Schell, JC | 1 |
| Nowinski, SM | 1 |
| Fogarty, S | 1 |
| Bott, AJ | 1 |
| Wei, P | 1 |
| Dove, KK | 1 |
| Tanner, JM | 1 |
| Panic, V | 1 |
| Cluntun, A | 1 |
| Lettlova, S | 1 |
| Earl, CS | 1 |
| Namnath, DF | 1 |
| Vázquez-Arreguín, K | 1 |
| Villanueva, CJ | 1 |
| Tantin, D | 1 |
| Murtaugh, LC | 1 |
| Evason, KJ | 1 |
| Ducker, GS | 1 |
| Thummel, CS | 1 |
| Rutter, J | 1 |
| Ohshima, K | 1 |
| Nojima, S | 1 |
| Tahara, S | 1 |
| Kurashige, M | 1 |
| Kawasaki, K | 1 |
| Hori, Y | 1 |
| Taniguchi, M | 1 |
| Umakoshi, Y | 1 |
| Okuzaki, D | 1 |
| Wada, N | 1 |
| Ikeda, JI | 1 |
| Fukusaki, E | 1 |
| Morii, E | 1 |
| Gu, J | 1 |
| Xiao, Y | 1 |
| Shu, D | 1 |
| Liang, X | 1 |
| Hu, X | 1 |
| Xie, Y | 1 |
| Lin, D | 1 |
| Li, H | 1 |
| Kannerup, AS | 1 |
| Grønbæk, H | 1 |
| Funch-Jensen, P | 1 |
| Karlsen, S | 1 |
| Mortensen, FV | 1 |
2 reviews available for pyruvic acid and Colorectal Neoplasms
| Article | Year |
|---|---|
Urine NMR Metabolomics for Precision Oncology in Colorectal Cancer.
Topics: Acetates; Acetone; Biomarkers; Carnitine; Colorectal Neoplasms; Creatinine; Glucose; Humans; Lysine; | 2022 |
Genetically predicted 486 blood metabolites in relation to risk of colorectal cancer: A Mendelian randomization study.
Topics: Colorectal Neoplasms; Databases, Factual; Genome-Wide Association Study; Humans; Mendelian Randomiza | 2023 |
6 other studies available for pyruvic acid and Colorectal Neoplasms
| Article | Year |
|---|---|
Glucose Conferred Irinotecan Chemoresistance through Divergent Actions of Pyruvate and ATP in Cell Death and Proliferation of Colorectal Cancer.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colo | 2022 |
Pretreatment optimization of tissue metabolomics in colorectal cancer.
Topics: Choline; Colorectal Neoplasms; Creatine; Glucose; Glycerylphosphorylcholine; Humans; Lactates; Nitro | 2022 |
Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.
Topics: Adenoma; Animals; Carcinogenesis; Cell Transformation, Neoplastic; Colorectal Neoplasms; Drosophila; | 2020 |
Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Heterografts; Humans; Mice; Mic | 2020 |
Metabolomics Analysis in Serum from Patients with Colorectal Polyp and Colorectal Cancer by
Topics: Acetates; Amino Acids; Biomarkers; Citrates; Colonic Polyps; Colorectal Neoplasms; Glycerol; Humans; | 2019 |
Partial liver ischemia is followed by metabolic changes in the normally perfused part of the liver during reperfusion.
Topics: Animals; Colorectal Neoplasms; Disease Models, Animal; Female; Glucose; Glycerol; Humans; Ischemia; | 2010 |