pyruvic acid has been researched along with Colonic Neoplasms in 7 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We determined in HT-29 human colon cancer cells whether ALA is able to affect apoptosis, as an important parameter disregulated in tumour development." | 1.33 | alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation. ( Daniel, H; Nickel, A; Wenzel, U, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Atalay, EB | 1 |
| Kayali, HA | 1 |
| Mungo, E | 1 |
| Bergandi, L | 1 |
| Salaroglio, IC | 1 |
| Doublier, S | 1 |
| Ramirez, MS | 1 |
| Lee, J | 1 |
| Walker, CM | 1 |
| Chen, Y | 1 |
| Kingsley, CV | 1 |
| De La Cerda, J | 1 |
| Maldonado, KL | 1 |
| Lai, SY | 1 |
| Bankson, JA | 1 |
| Saito, K | 1 |
| Matsumoto, S | 1 |
| Takakusagi, Y | 1 |
| Matsuo, M | 1 |
| Morris, HD | 1 |
| Lizak, MJ | 1 |
| Munasinghe, JP | 1 |
| Devasahayam, N | 1 |
| Subramanian, S | 1 |
| Mitchell, JB | 1 |
| Krishna, MC | 1 |
| Jansson, K | 1 |
| Ungerstedt, J | 1 |
| Jonsson, T | 1 |
| Redler, B | 1 |
| Andersson, M | 1 |
| Ungerstedt, U | 1 |
| Norgren, L | 1 |
| Wenzel, U | 1 |
| Nickel, A | 1 |
| Daniel, H | 1 |
| Singh, B | 1 |
| Halestrap, AP | 1 |
| Paraskeva, C | 1 |
7 other studies available for pyruvic acid and Colonic Neoplasms
| Article | Year |
|---|---|
The elevated D-2-hydroxyglutarate level found as a characteristic metabolic change of colon cancer in both in vitro and in vivo models.
Topics: Adenocarcinoma; Caco-2 Cells; Colonic Neoplasms; Glucose; Glutarates; Humans; Isocitrate Dehydrogena | 2022 |
Pyruvate Treatment Restores the Effectiveness of Chemotherapeutic Agents in Human Colon Adenocarcinoma and Pleural Mesothelioma Cells.
Topics: Acrylates; Adenocarcinoma; Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Trans | 2018 |
Feasibility of multianimal hyperpolarized (13) C MRS.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Colonic Neoplasms; Cost-Benefit Analysis; Energy | 2015 |
13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors.
Topics: Animals; Carbon Isotopes; Carcinoma, Squamous Cell; Colonic Neoplasms; HT29 Cells; Humans; Lactic Ac | 2015 |
Human intraperitoneal microdialysis: increased lactate/pyruvate ratio suggests early visceral ischaemia. A pilot study.
Topics: Aged; Aged, 80 and over; Colonic Neoplasms; Female; Humans; Intestines; Ischemia; Lactic Acid; Male; | 2003 |
alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation.
Topics: Angiogenesis Inhibitors; Apoptosis; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Cytosol; DNA | 2005 |
Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources.
Topics: Adenoma; Apoptosis; Butyrates; Butyric Acid; Cell Division; Cell Line; Colon; Colonic Neoplasms; Cul | 1997 |