Page last updated: 2024-10-20

pyruvic acid and Citrullinemia

pyruvic acid has been researched along with Citrullinemia in 7 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Citrullinemia: A group of diseases related to a deficiency of the enzyme ARGININOSUCCINATE SYNTHASE which causes an elevation of serum levels of CITRULLINE. In neonates, clinical manifestations include lethargy, hypotonia, and SEIZURES. Milder forms also occur. Childhood and adult forms may present with recurrent episodes of intermittent weakness, lethargy, ATAXIA, behavioral changes, and DYSARTHRIA. (From Menkes, Textbook of Child Neurology, 5th ed, p49)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saheki, T6
Moriyama, M2
Kuroda, E2
Funahashi, A1
Yasuda, I1
Setogawa, Y1
Gao, Q1
Ushikai, M2
Furuie, S2
Yamamura, KI1
Takano, K1
Nakamura, Y2
Eto, K2
Kadowaki, T2
Sinasac, DS3
Furukawa, T1
Horiuchi, M2
Tai, YH1
Mutoh, K1
Kurokawa, K1
Kobayashi, K4
Yazaki, M2
Ikeda, S2
Inoue, K1
Ono, H1
Katsura, N1
Yokogawa, M1
Yoshidumi, Y1
Asakawa, A1
Inui, A1
Yamamura, K1
Kinoshita, M1
Ogawa, S1
Fujimi, S1
Matsushima, A1
Hineno, A1
Tazawa, K1
Fukushima, K1
Kimura, R1
Yanagida, M1
Matsunaga, H1
Li, MX1
Kannan, Y1
Iijima, M1
Tsui, LC1
Tanaka, M1
Larovere, L1
Latini, A1
Depetris-Boldini, C1
Coronel, CE1
de Kremer, RD1

Other Studies

7 other studies available for pyruvic acid and Citrullinemia

ArticleYear
Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model.
    Scientific reports, 2019, 03-12, Volume: 9, Issue:1

    Topics: Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Citrulline; Citrullinemia; Disease

2019
Treatment of a citrin-deficient patient at the early stage of adult-onset type II citrullinaemia with arginine and sodium pyruvate.
    Journal of inherited metabolic disease, 2008, Volume: 31 Suppl 2

    Topics: Administration, Oral; Adolescent; Arginine; Biomarkers; Citrullinemia; Diet, Carbohydrate-Restricted

2008
[Therapeutic approaches for patients with adult-onset type II citrullinemia (CTLN2): effectiveness of treatment with low-carbohydrate diet and sodium pyruvate].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Aged; Calcium-Binding Proteins; Child; Citrullinemia; Diet,

2010
Effects of supplementation on food intake, body weight and hepatic metabolites in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse model of human citrin deficiency.
    Molecular genetics and metabolism, 2012, Volume: 107, Issue:3

    Topics: Alanine; Animals; Body Weight; Cholestasis, Intrahepatic; Citrullinemia; Dietary Proteins; Disease M

2012
A 73-year-old patient with adult-onset type II citrullinemia successfully treated by sodium pyruvate and arginine.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:8

    Topics: Aged; Ammonia; Arginine; Blood Chemical Analysis; Citrullinemia; Consciousness Disorders; Female; Hu

2013
Pyruvate ameliorates the defect in ureogenesis from ammonia in citrin-deficient mice.
    Journal of hepatology, 2006, Volume: 44, Issue:5

    Topics: Amino Acids; Ammonia; Animals; Anticoagulants; Aspartic Acid; Calcium-Binding Proteins; Citric Acid;

2006
Cerebrospinal fluid purines, pyrimidines, organic acids and amino acids in neonatal citrullinaemia.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: 3-Hydroxybutyric Acid; Amino Acids; Child; Child, Preschool; Citrullinemia; Humans; Infant; Infant,

2000