pyruvic acid has been researched along with Cirrhosis, Liver in 19 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "By central venous catheterization, 6 control persons, 7 patients with liver cirrhosis and 6 patients with diabetes mellitus were infused for 48 h with a 20% (w/v) mixture of glucose/xylitol (1:1)." | 3.66 | [Carbohydrate infusion in internal diseases. A comparative study in metabolically healthy, liver diseased and diabetic patients. VI. Infusions of a glucose/xylitol mixture (1:1 ratio) over a 48-hour period]. ( Egberts, EH; Horbach, L; Malchow, H; Müller, PH; Prestele, H; Rittershofer, H; Schmülling, R, 1982) |
| "The major obstacle for the development of targeted therapies is the lack of pharmacodynamic (PD) biomarkers to provide an early readout of biological activities." | 1.46 | Metabolomics combined with pattern recognition and bioinformatics analysis methods for the development of pharmacodynamic biomarkers on liver fibrosis. ( Fang, J; Qiu, M; Wang, L; Wang, Y; Zhang, Y, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (63.16) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, J | 1 |
| Wang, L | 1 |
| Wang, Y | 1 |
| Qiu, M | 1 |
| Zhang, Y | 1 |
| Allen, J | 1 |
| Zhang, J | 1 |
| Quickel, MD | 1 |
| Kennett, M | 1 |
| Patterson, AD | 1 |
| Hankey-Giblin, PA | 1 |
| IAGNOV, S | 1 |
| ZAMFIRESCU-GHEORGHIU, M | 1 |
| STROHMEYER, G | 1 |
| MARTINI, GA | 1 |
| KLINGMULLER, V | 1 |
| HOENIG, V | 1 |
| HOENIGOVA, J | 1 |
| GORDON, EE | 1 |
| CRAIGIE, A | 1 |
| KONO, H | 2 |
| ORREGO, H | 1 |
| WALSHE, JM | 1 |
| BRAVO, M | 1 |
| Strauss, GI | 1 |
| Møller, K | 1 |
| Larsen, FS | 1 |
| Kondrup, J | 1 |
| Knudsen, GM | 1 |
| Shangraw, RE | 1 |
| Jahoor, F | 1 |
| Salerno, F | 2 |
| Abbiati, R | 2 |
| Fici, F | 2 |
| Lorenzini, MC | 1 |
| Conti, M | 1 |
| Alberti, KG | 1 |
| Johnston, DG | 1 |
| Piniewska-Hulas, M | 1 |
| Whittaker, J | 1 |
| Egberts, EH | 1 |
| Rittershofer, H | 1 |
| Müller, PH | 1 |
| Schmülling, R | 1 |
| Prestele, H | 1 |
| Horbach, L | 1 |
| Malchow, H | 1 |
| Sewell, AC | 1 |
| Herwig, J | 1 |
| Böhles, HJ | 1 |
| Sperl, W | 1 |
| Sadiq, M | 1 |
| Baseer, A | 1 |
| Mizobuchi, N | 1 |
| Kuwao, F | 1 |
| Takeda, I | 1 |
| Takemura, T | 1 |
| Morita, S | 1 |
| Horimi, T | 1 |
| Takahashi, I | 1 |
1 review available for pyruvic acid and Cirrhosis, Liver
| Article | Year |
|---|---|
Disturbances of metabolic homeostasis is liver disease.
Topics: Fasting; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Growth Hormone; Homeostasis; Humans; Hyd | 1981 |
2 trials available for pyruvic acid and Cirrhosis, Liver
| Article | Year |
|---|---|
Mechanism of dichloroacetate-induced hypolactatemia in humans with or without cirrhosis.
Topics: Adult; Alanine; C-Peptide; Dichloroacetic Acid; Female; Gas Chromatography-Mass Spectrometry; Glucag | 2004 |
Effect of pyridoxine-2-oxoglutarate administration in patients with advanced cirrhosis: control of ammonia pyruvate and lactate high plasma concentrations.
Topics: Amino Acids; Ammonia; Blood Glucose; Clinical Trials as Topic; Double-Blind Method; Humans; Lactates | 1982 |
16 other studies available for pyruvic acid and Cirrhosis, Liver
| Article | Year |
|---|---|
Metabolomics combined with pattern recognition and bioinformatics analysis methods for the development of pharmacodynamic biomarkers on liver fibrosis.
Topics: Amino Acids; Ammonia; Animals; Biomarkers; Carbon Tetrachloride; Eosine Yellowish-(YS); Gas Chromato | 2017 |
Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model.
Topics: Animals; Apolipoproteins E; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Collagen; Cytokines; D | 2018 |
PYRUVATE metabolism in diabetes and liver cirrhosis.
Topics: Diabetes Mellitus; Humans; Liver Cirrhosis; Pyruvates; Pyruvic Acid | 1953 |
[Test of urinary elimination of carbonyl substances in the form of pyruvic acid, during epidemic hepatitis, chronic hepatitis and cirrhosis].
Topics: Hepatitis; Hepatitis A; Hepatitis, Chronic; Humans; Liver Cirrhosis; Pyruvates; Pyruvic Acid | 1957 |
[Changes of alpha-ketoglutaric acid, pyruvic acid and diphosphopyridine nucleotide in chronic liver diseases].
Topics: Coenzymes; Glutarates; Humans; Ketoglutaric Acids; Liver Cirrhosis; Liver Diseases; NAD; Pyruvates; | 1957 |
[Increased urinary pyruvate excretion after fructose administration].
Topics: Fructose; Humans; Ileum; Liver Cirrhosis; Pyruvates; Pyruvic Acid | 1958 |
Effect of intravenous glucose on splanchnic and peripheral metabolism of endogenous pyruvate and citrate in patients with cirrhosis and in subjects without liver disease.
Topics: Citrates; Citric Acid; Glucose; Humans; Liver; Liver Cirrhosis; Liver Diseases; Pyruvates; Pyruvic A | 1960 |
[CLINICAL INVESTIGATIONS OF PYRUVIC ACID METABOLISM IN LIVER DISEASES. I. PYRUVIC ACID LEVEL OF THE BLOOD IN LIVER DISEASES AND ITS DYNAMICS].
Topics: Alanine Transaminase; Blood Chemical Analysis; Clinical Enzyme Tests; Hepatitis; Hepatitis A; Humans | 1964 |
[CLINICAL RESEARCH ON PYRUVIC ACID METABOLISM IN LIVER DISEASES. II. EFFECTS OF DIFFERENT DRUGS ON THE PYRUVIC ACID BLOOD LEVEL IN LIVER DISEASES].
Topics: Adrenal Cortex Hormones; Asparagine; Blood Chemical Analysis; Glucose; Hepatitis; Hepatitis A; Liver | 1964 |
[Lactic and pyruvic acids in liver cirrhosis before and after the oral administration of glucose. Influence of thioctic acid on such acids].
Topics: Administration, Oral; Glucose; Lactates; Liver Cirrhosis; Pyruvates; Pyruvic Acid; Thioctic Acid | 1959 |
Cerebral glucose and oxygen metabolism in patients with fulminant hepatic failure.
Topics: Acetoacetates; Brain; Humans; Lactic Acid; Liver Cirrhosis; Liver Failure; Oxygen; Oxygen Consumptio | 2003 |
Effect of pyridoxine alpha-ketoglutarate (PAK) on ammonia and pyruvic and lactic acid blood levels in patients with cirrhosis.
Topics: Aged; Amino Acids; Ammonia; Blood Glucose; Double-Blind Method; Drug Evaluation; Female; Humans; Lac | 1983 |
[Carbohydrate infusion in internal diseases. A comparative study in metabolically healthy, liver diseased and diabetic patients. VI. Infusions of a glucose/xylitol mixture (1:1 ratio) over a 48-hour period].
Topics: Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Glucose Solution, Hypertonic; | 1982 |
Mitochondrial respiratory chain succinate-cytochrome-c oxidoreductase deficiency and hepatic cirrhosis.
Topics: Electron Transport; Fatal Outcome; Humans; Infant; Lactic Acid; Liver; Liver Cirrhosis; Male; Mitoch | 1997 |
Carbohydrate metabolism in liver cirrhosis.
Topics: Adult; Blood Glucose; Female; Humans; Insulin; Liver; Liver Cirrhosis; Male; Pyruvates; Pyruvic Acid | 1991 |
[Changes in ketone body ratio and levels of pyruvate and lactate in arterial blood of patients with hepatocellular carcinoma after transcatheter arterial embolization].
Topics: Carcinoma, Hepatocellular; Embolization, Therapeutic; Humans; Ketones; Lactates; Lactic Acid; Liver; | 1990 |