pyruvic acid has been researched along with Chronic Primary Open Angle Glaucoma in 4 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of these, 42 patients with treated open-angle glaucoma and moderate visual field loss in at least 1 eye were selected for inclusion and randomized." | 1.72 | Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial. ( Blumberg, DM; Cioffi, GA; De Moraes, CG; John, SWM; Liebmann, JM; Williams, PA, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Moraes, CG | 2 |
| John, SWM | 1 |
| Williams, PA | 1 |
| Blumberg, DM | 1 |
| Cioffi, GA | 1 |
| Liebmann, JM | 2 |
| Quah Qin Xian, N | 1 |
| Wong, FYK | 1 |
| Sander, EA | 1 |
| Nauman, EA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study[NCT05695027] | Phase 2/Phase 3 | 188 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| Nutritional Supplements and Performance During Visual Field Testing[NCT03797469] | 32 participants (Actual) | Interventional | 2019-04-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for pyruvic acid and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Combined Use of Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma-Reply.
Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Niacinamide; Pyruvic Acid | 2022 |
Combined Use of Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma.
Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Niacinamide; Pyruvic Acid | 2022 |
Effects of reduced oxygen and glucose levels on ocular cells in vitro: implications for tissue models.
Topics: Animals; Astrocytes; Cell Proliferation; Cells, Cultured; Glaucoma, Open-Angle; Glucose; Glutamic Ac | 2010 |