pyruvic acid has been researched along with Cerebral Infarction in 19 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The focal cerebral ischemia was produced by the occlusion of the right common carotid artery and the right middle cerebral artery for 60 mins." | 5.31 | Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique. ( Cheng, FC; Chung, SY; Lin, JY; Lin, MC, 2002) |
| "Delayed cerebral ischemia (DCI) is a devastating complication of aneurysmal subarachnoid hemorrhage (ASAH) causing brain infarction and disability." | 1.91 | Early brain metabolic disturbances associated with delayed cerebral ischemia in patients with severe subarachnoid hemorrhage. ( Aboudhiaf, S; Balança, B; Barcelos, GK; Carrillon, R; Dailler, F; Grousson, S; Lieutaud, T; Marinesco, S; Perret-Liaudet, A; Tholance, Y, 2023) |
| "After cardiac resuscitation, hypoxic encephalopathy often is the limiting factor regarding outcome due to the oxygen sensitivity of the brain." | 1.32 | Neurochemical monitoring using intracerebral microdialysis during cardiac resuscitation. ( Barbach, J; Bauer, R; Gabl, M; Galiano, K; Mohsenipour, I; Obwegeser, A, 2004) |
| "Forty patients (35 after subarachnoid hemorrhage and 5 after complex aneurysm surgery) were monitored for a total of 174 days (mean, 4 d; range, 1-12 d)." | 1.31 | Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes. ( Al-Rawi, PG; Gupta, AK; Hutchinson, PJ; Kett-White, R; Kirkpatrick, PJ; Pickard, JD, 2002) |
| "The focal cerebral ischemia was produced by the occlusion of the right common carotid artery and the right middle cerebral artery for 60 mins." | 1.31 | Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique. ( Cheng, FC; Chung, SY; Lin, JY; Lin, MC, 2002) |
| "Seventeen patients with recent cerebral infarction were included in the study." | 1.27 | [Changes in organic acids in plasma and cerebrospinal fluid in cerebral infarct]. ( Bruck, J; Rausch, WD; Riederer, P; Schnecker, K, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Tholance, Y | 1 |
| Aboudhiaf, S | 1 |
| Balança, B | 1 |
| Barcelos, GK | 1 |
| Grousson, S | 1 |
| Carrillon, R | 1 |
| Lieutaud, T | 1 |
| Perret-Liaudet, A | 1 |
| Dailler, F | 1 |
| Marinesco, S | 1 |
| Diaz, F | 1 |
| Raval, AP | 1 |
| Pinczolits, A | 2 |
| Zdunczyk, A | 1 |
| Dengler, NF | 1 |
| Hecht, N | 2 |
| Kowoll, CM | 1 |
| Dohmen, C | 1 |
| Graf, R | 1 |
| Winkler, MK | 1 |
| Major, S | 1 |
| Hartings, JA | 1 |
| Dreier, JP | 2 |
| Vajkoczy, P | 2 |
| Woitzik, J | 2 |
| Sandow, N | 1 |
| Scheel, M | 1 |
| Drenckhahn, C | 1 |
| Nordström, CH | 1 |
| Nielsen, TH | 1 |
| Schalén, W | 1 |
| Reinstrup, P | 1 |
| Ungerstedt, U | 1 |
| Helbok, R | 1 |
| Madineni, RC | 1 |
| Schmidt, MJ | 1 |
| Kurtz, P | 1 |
| Fernandez, L | 1 |
| Ko, SB | 1 |
| Choi, A | 1 |
| Stuart, MR | 1 |
| Connolly, ES | 1 |
| Lee, K | 1 |
| Badjatia, N | 1 |
| Mayer, SA | 1 |
| Khandji, AG | 1 |
| Claassen, J | 1 |
| Bauer, R | 1 |
| Gabl, M | 1 |
| Obwegeser, A | 1 |
| Galiano, K | 1 |
| Barbach, J | 1 |
| Mohsenipour, I | 1 |
| Yi, JS | 1 |
| Kim, TY | 1 |
| Kyu Kim, D | 1 |
| Koh, JY | 1 |
| Hiraoka, A | 1 |
| Akai, J | 1 |
| Tominaga, I | 1 |
| Hattori, M | 1 |
| Sasaki, H | 1 |
| Arato, T | 1 |
| Berger, C | 1 |
| Annecke, A | 1 |
| Aschoff, A | 1 |
| Spranger, M | 1 |
| Schwab, S | 1 |
| Anderson, MF | 1 |
| Sims, NR | 1 |
| Krasińska-Czerlunczakiewicz, H | 1 |
| Pilarczyk, M | 1 |
| Stelmasiak, Z | 2 |
| Kett-White, R | 2 |
| Hutchinson, PJ | 2 |
| Al-Rawi, PG | 2 |
| Gupta, AK | 2 |
| Pickard, JD | 2 |
| Kirkpatrick, PJ | 2 |
| Czosnyka, M | 1 |
| Lin, JY | 1 |
| Chung, SY | 1 |
| Lin, MC | 1 |
| Cheng, FC | 1 |
| Siesjö, BK | 1 |
| Ingvar, M | 1 |
| Wieloch, T | 1 |
| Kawiak, W | 1 |
| Nowicki, J | 1 |
| Hasiec, T | 1 |
| Gieracz-Nazar, A | 1 |
| Wróblewski, L | 1 |
| Hara, T | 1 |
| Yokoi, F | 1 |
| Iio, M | 1 |
| Rausch, WD | 1 |
| Schnecker, K | 1 |
| Bruck, J | 1 |
| Riederer, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multimodality Monitoring Directed Management of Patients Suffering From Traumatic Brain Injury[NCT02993549] | 100 participants (Anticipated) | Observational | 2017-09-16 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvic acid and Cerebral Infarction
| Article | Year |
|---|---|
Cellular and molecular events underlying epileptic brain damage.
Topics: Acidosis; Animals; Brain; Brain Damage, Chronic; Calcium; Cell Survival; Cerebral Infarction; Electr | 1986 |
2 trials available for pyruvic acid and Cerebral Infarction
| Article | Year |
|---|---|
[Evaluation of pyruvic acid concentration in blood of patients with ischemic stroke in the earliest stage of the disease].
Topics: Cerebral Infarction; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Pyruvic Acid | 1999 |
Cerebral oxygen and microdialysis monitoring during aneurysm surgery: effects of blood pressure, cerebrospinal fluid drainage, and temporary clipping on infarction.
Topics: Adult; Aged; Blood Pressure; Cerebral Infarction; Cerebrospinal Fluid; Drainage; Female; Glucose; Gl | 2002 |
16 other studies available for pyruvic acid and Cerebral Infarction
| Article | Year |
|---|---|
Early brain metabolic disturbances associated with delayed cerebral ischemia in patients with severe subarachnoid hemorrhage.
Topics: Brain; Brain Ischemia; Cerebral Infarction; Glucose; Glutamic Acid; Humans; Lactic Acid; Pyruvic Aci | 2023 |
Simultaneous nicotine and oral contraceptive exposure alters brain energy metabolism and exacerbates ischemic stroke injury in female rats.
Topics: Animals; Brain; Cerebral Infarction; Citric Acid Cycle; Contraceptives, Oral, Hormonal; Energy Metab | 2021 |
Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke.
Topics: Cerebral Cortex; Cerebral Infarction; Cortical Spreading Depression; Electrocorticography; Female; G | 2017 |
Excitotoxicity and metabolic changes in association with infarct progression.
Topics: Adult; Aged; Aged, 80 and over; Brain; Cerebral Infarction; Disease Progression; Female; Glucose; Gl | 2014 |
Biochemical indications of cerebral ischaemia and mitochondrial dysfunction in severe brain trauma analysed with regard to type of lesion.
Topics: Adult; Brain Injuries, Traumatic; Brain Ischemia; Cerebral Infarction; Energy Metabolism; Female; Gl | 2016 |
Intracerebral monitoring of silent infarcts after subarachnoid hemorrhage.
Topics: Adult; Asymptomatic Diseases; Brain; Cerebral Infarction; Critical Care; Female; Glucose; Humans; La | 2011 |
Neurochemical monitoring using intracerebral microdialysis during cardiac resuscitation.
Topics: Adult; Biomarkers; Brain Chemistry; Cause of Death; Cerebral Infarction; Energy Metabolism; Fatal Ou | 2004 |
Systemic pyruvate administration markedly reduces infarcts and motor deficits in rat models of transient and permanent focal cerebral ischemia.
Topics: Animals; Brain; Brain Chemistry; Brain Ischemia; Cell Death; Cerebral Infarction; Dose-Response Rela | 2007 |
Capillary zone electrophoretic determination of organic acids in cerebrospinal fluid from patients with central nervous system diseases.
Topics: Brain Diseases; Cerebral Infarction; Electrophoresis; Humans; Lactates; Lactic Acid; Meningitis, Bac | 1994 |
Neurochemical monitoring of fatal middle cerebral artery infarction.
Topics: Adult; Biomarkers; Brain Edema; Cerebral Arteries; Cerebral Cortex; Cerebral Infarction; Fatal Outco | 1999 |
Mitochondrial respiratory function and cell death in focal cerebral ischemia.
Topics: Animals; Arterial Occlusive Diseases; Cell Death; Cerebral Arterial Diseases; Cerebral Infarction; I | 1999 |
Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes.
Topics: Brain; Brain Ischemia; Carbon Dioxide; Cerebral Angiography; Cerebral Infarction; Disabled Persons; | 2002 |
Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Energy Metabolism; Gerbillinae; Gluco | 2002 |
[Glucose, lactic acid and pyruvic acid levels of the blood and cerebrospinal fluid in patients with diabetes mellitus and cerebral infarction].
Topics: Aged; Blood Glucose; Cerebral Infarction; Diabetes Mellitus; Female; Glucose; Humans; Lactates; Lact | 1987 |
Brain ischemia and infarction positively visualized by pyruvate-1-11C using positron-emission tomography.
Topics: Adult; Aged; Brain Ischemia; Carbon Radioisotopes; Cerebral Infarction; Female; Humans; Male; Middle | 1986 |
[Changes in organic acids in plasma and cerebrospinal fluid in cerebral infarct].
Topics: Aged; Aged, 80 and over; Blood-Brain Barrier; Cerebral Infarction; Citrates; Citric Acid; Female; Fo | 1987 |