Page last updated: 2024-10-20

pyruvic acid and Cardiomyopathy, Congestive

pyruvic acid has been researched along with Cardiomyopathy, Congestive in 6 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Research Excerpts

ExcerptRelevanceReference
" This association is suggestive of the MIDD syndrome and the demonstration of metabolic abnormalities (raised serum lactic acid, abnormal lactate/pyruvate ratio) was compatible with a mitochondrial disease."3.74[Dilated cardiomyopathy, diabetes and deafness related to a mutation of mitochondrial DNA]. ( Charbonnier, B; Ferreira-Maldent, N; Guilmot, JL; Maillot, F; Quilliet, L, 2007)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Zhang, Y1
Taufalele, PV1
Cochran, JD1
Robillard-Frayne, I1
Marx, JM1
Soto, J1
Rauckhorst, AJ1
Tayyari, F1
Pewa, AD1
Gray, LR1
Teesch, LM1
Puchalska, P1
Funari, TR1
McGlauflin, R1
Zimmerman, K1
Kutschke, WJ1
Cassier, T1
Hitchcock, S1
Lin, K1
Kato, KM1
Stueve, JL1
Haff, L1
Weiss, RM1
Cox, JE1
Rutter, J1
Taylor, EB1
Crawford, PA1
Lewandowski, ED1
Des Rosiers, C1
Abel, ED1
Obrzut, S1
Tiongson, J1
Jamshidi, N1
Phan, HM1
Hoh, C1
Birgersdotter-Green, U1
Schroeder, MA1
Lau, AZ1
Chen, AP1
Gu, Y1
Nagendran, J1
Barry, J1
Hu, X1
Dyck, JR1
Tyler, DJ1
Clarke, K1
Connelly, KA1
Wright, GA1
Cunningham, CH1
Westenbrink, BD1
Dorn, GW1
Ferreira-Maldent, N1
Maillot, F1
Quilliet, L1
Guilmot, JL1
Charbonnier, B1
Hermann, HP1
Pieske, B1
Schwarzmüller, E1
Keul, J1
Just, H1
Hasenfuss, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hyperpolarized MRSI in Ischemic Heart Disease: Metabolic Profiling of the Myocardium[NCT06054516]15 participants (Anticipated)Observational2023-10-13Recruiting
Effects of Pyruvate in Patients With Cardiogenic Shock and Intra-aortic Balloon Counterpulsation[NCT00604331]Phase 28 participants (Actual)Interventional2008-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for pyruvic acid and Cardiomyopathy, Congestive

ArticleYear
Haemodynamic effects of intracoronary pyruvate in patients with congestive heart failure: an open study.
    Lancet (London, England), 1999, Apr-17, Volume: 353, Issue:9161

    Topics: Cardiac Catheterization; Cardiomyopathy, Dilated; Coronary Vessels; Female; Heart Failure; Hemodynam

1999

Other Studies

5 other studies available for pyruvic acid and Cardiomyopathy, Congestive

ArticleYear
Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
    Nature metabolism, 2020, Volume: 2, Issue:11

    Topics: Adaptation, Physiological; Animals; Anion Transport Proteins; Cardiomegaly; Cardiomyopathy, Dilated;

2020
Assessment of metabolic phenotypes in patients with non-ischemic dilated cardiomyopathy undergoing cardiac resynchronization therapy.
    Journal of cardiovascular translational research, 2010, Volume: 3, Issue:6

    Topics: Adenosine Triphosphate; Adult; Aged; Amino Acids; Biomarkers; Blood Glucose; Cardiac Resynchronizati

2010
Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart.
    European journal of heart failure, 2013, Volume: 15, Issue:2

    Topics: Adenosine Triphosphate; Animals; Bicarbonates; Carbon Isotopes; Cardiac Pacing, Artificial; Cardiac

2013
Imaging the cardiac diet.
    European journal of heart failure, 2013, Volume: 15, Issue:2

    Topics: Animals; Cardiomyopathy, Dilated; Disease Models, Animal; Energy Metabolism; Glycolysis; Heart Failu

2013
[Dilated cardiomyopathy, diabetes and deafness related to a mutation of mitochondrial DNA].
    Archives des maladies du coeur et des vaisseaux, 2007, Volume: 100, Issue:2

    Topics: Cardiomyopathy, Dilated; Deafness; Diabetes Mellitus; DNA, Mitochondrial; Female; Humans; Lactic Aci

2007