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pyruvic acid and Cardiomyopathies

pyruvic acid has been researched along with Cardiomyopathies in 11 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"Treatment with thiamine and carnitine resulted in a decrease in blood lactate to normal levels and a dramatic clinical improvement."5.28Neonatal cardiomyopathy and lactic acidosis responsive to thiamine. ( Abeling, NG; Bakker, HD; Lam, J; Luyt-Houwen, IE; Scholte, HR; van Gennip, AH, 1991)
"Treatment with thiamine and carnitine resulted in a decrease in blood lactate to normal levels and a dramatic clinical improvement."1.28Neonatal cardiomyopathy and lactic acidosis responsive to thiamine. ( Abeling, NG; Bakker, HD; Lam, J; Luyt-Houwen, IE; Scholte, HR; van Gennip, AH, 1991)
"Verapamil-treated myopathic hamsters had evidence of markedly improved mitochondrial function when compared with untreated animals."1.27Evaluation of the hereditary Syrian hamster cardiomyopathy by 31P nuclear magnetic resonance spectroscopy: improvement after acute verapamil therapy. ( Higgins, CB; James, TL; Jasmin, G; Markiewicz, W; Parmley, WW; Sievers, R; Wikman-Coffelt, J; Wu, SS, 1986)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Shimada, BK1
Boyman, L1
Huang, W1
Zhu, J1
Yang, Y1
Chen, F1
Kane, MA1
Yadava, N1
Zou, L1
Lederer, WJ1
Polster, BM1
Chao, W1
Hiraki, N1
Tanaka, TD1
Yoshimura, M1
Mallet, RT1
Sun, J1
Knott, EM1
Sharma, AB1
Olivencia-Yurvati, AH1
Zhao, G1
Jeoung, NH1
Burgess, SC1
Rosaaen-Stowe, KA1
Inagaki, T1
Latif, S1
Shelton, JM1
McAnally, J1
Bassel-Duby, R1
Harris, RA1
Richardson, JA1
Kliewer, SA1
Dionisi-Vici, C1
Ruitenbeek, W1
Fariello, G1
Bentlage, H1
Wanders, RJ1
Schägger, H1
Bosman, C1
Piantadosi, C1
Sabetta, G1
Bertini, E1
Ngai, SM1
Way, MM1
Chan, H1
Tsui, SK1
Lee, CY1
Fung, KP1
Wikman-Coffelt, J2
Stefenelli, T1
Wu, ST1
Parmley, WW2
Jasmin, G2
Bakker, HD1
Scholte, HR1
Luyt-Houwen, IE1
van Gennip, AH1
Abeling, NG1
Lam, J1
Bachmann, E1
Weber, E1
Ruddy, TD1
Shumak, SL1
Liu, PP1
Barnie, A1
Seawright, SJ1
McLaughlin, PR1
Zinman, B1
Markiewicz, W1
Wu, SS1
Higgins, CB1
Sievers, R1
James, TL1

Reviews

1 review available for pyruvic acid and Cardiomyopathies

ArticleYear
Metabolic cardioprotection by pyruvate: recent progress.
    Experimental biology and medicine (Maywood, N.J.), 2005, Volume: 230, Issue:7

    Topics: Animals; Antioxidants; Cardiomyopathies; Cardiotonic Agents; Humans; Myocardium; Pyruvic Acid

2005

Other Studies

10 other studies available for pyruvic acid and Cardiomyopathies

ArticleYear
Pyruvate-Driven Oxidative Phosphorylation is Downregulated in Sepsis-Induced Cardiomyopathy: A Study of Mitochondrial Proteome.
    Shock (Augusta, Ga.), 2022, 04-01, Volume: 57, Issue:4

    Topics: Animals; Cardiomyopathies; Male; Mice; Mitochondria; Mitochondrial Proteins; Myocardium; Oxidative P

2022
A Man With Left Ventricular Hypertrophy.
    JAMA cardiology, 2022, 02-01, Volume: 7, Issue:2

    Topics: Adult; Atrophy; Cardiomyopathies; Cerebellar Diseases; Cognitive Dysfunction; Echocardiography; Gluc

2022
Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:2

    Topics: Aging; Animals; Blotting, Western; Calcineurin; Cardiomyopathies; Humans; Lactic Acid; Mice; Mice, T

2008
New familial mitochondrial encephalopathy with macrocephaly, cardiomyopathy, and complex I deficiency.
    Annals of neurology, 1997, Volume: 42, Issue:4

    Topics: Cardiomyopathies; Electrophoresis, Gel, Two-Dimensional; Family Health; Fatal Outcome; Fibroblasts;

1997
In silico studies of energy metabolism of normal and diseased heart.
    Molecular biology reports, 2000, Volume: 27, Issue:2

    Topics: Cardiomegaly; Cardiomyopathies; Computational Biology; Energy Metabolism; Expressed Sequence Tags; G

2000
[Ca2+]i transients in the cardiomyopathic hamster heart.
    Circulation research, 1991, Volume: 68, Issue:1

    Topics: Animals; Calcium; Cardiac Complexes, Premature; Cardiomyopathies; Cricetinae; Fluorescent Dyes; Fluo

1991
Neonatal cardiomyopathy and lactic acidosis responsive to thiamine.
    Journal of inherited metabolic disease, 1991, Volume: 14, Issue:1

    Topics: Acidosis, Lactic; Cardiomyopathies; Carnitine; Child; Child, Preschool; Female; Humans; Infant; Keto

1991
Recirculating, retrograde heart perfusion according to Langendorff as a tool in the evaluation of drug-induced cardiomyopathy: effects of a high lipid diet.
    Archives of toxicology, 1991, Volume: 65, Issue:6

    Topics: Animals; Cardiomyopathies; Creatine Kinase; Dietary Fats; Energy Metabolism; Female; Glycogen; L-Lac

1991
The relationship of cardiac diastolic dysfunction to concurrent hormonal and metabolic status in type I diabetes mellitus.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:1

    Topics: Adult; Blood Glucose; Cardiomyopathies; Diabetes Mellitus, Type 1; Diastole; Epinephrine; Female; Gl

1988
Evaluation of the hereditary Syrian hamster cardiomyopathy by 31P nuclear magnetic resonance spectroscopy: improvement after acute verapamil therapy.
    Circulation research, 1986, Volume: 59, Issue:6

    Topics: Adenosine Triphosphate; Animals; Cardiomyopathies; Cricetinae; Glucose; Hemodynamics; Hydrogen-Ion C

1986