pyruvic acid has been researched along with Carcinoma, Pancreatic Ductal in 7 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Carcinoma, Pancreatic Ductal: Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Resected pancreatic cancer (n = 21) and normal pancreas were laser-capture micro-dissected, and transcripts were quantified by RNAseq." | 1.48 | Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms. ( Bamlet, WR; Carlson, SK; Couch, FJ; Damgard, SE; Deelchand, DK; Kittelson, E; Marjańska, M; Murphy, SJ; O'Brien, DR; Passow, MR; Penheiter, AR; Port, JD; Smyrk, TC; Vasmatzis, G, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Kerk, SA | 1 |
| Lin, L | 1 |
| Myers, AL | 1 |
| Sutton, DJ | 1 |
| Andren, A | 1 |
| Sajjakulnukit, P | 1 |
| Zhang, L | 1 |
| Zhang, Y | 1 |
| Jiménez, JA | 1 |
| Nelson, BS | 1 |
| Chen, B | 1 |
| Robinson, A | 1 |
| Thurston, G | 1 |
| Kemp, SB | 1 |
| Steele, NG | 1 |
| Hoffman, MT | 1 |
| Wen, HJ | 1 |
| Long, D | 1 |
| Ackenhusen, SE | 1 |
| Ramos, J | 1 |
| Gao, X | 1 |
| Nwosu, ZC | 1 |
| Galban, S | 1 |
| Halbrook, CJ | 1 |
| Lombard, DB | 1 |
| Piwnica-Worms, DR | 1 |
| Ying, H | 1 |
| Pasca di Magliano, M | 1 |
| Crawford, HC | 1 |
| Shah, YM | 1 |
| Lyssiotis, CA | 1 |
| Li, X | 1 |
| Du, Y | 1 |
| Jiang, W | 1 |
| Dong, S | 1 |
| Li, W | 1 |
| Tang, H | 1 |
| Yi, J | 1 |
| Zhou, W | 1 |
| Zhang, H | 1 |
| Song, X | 1 |
| Liu, J | 1 |
| Kuang, F | 1 |
| Chen, X | 1 |
| Zeh, HJ | 1 |
| Kang, R | 1 |
| Kroemer, G | 1 |
| Xie, Y | 1 |
| Tang, D | 1 |
| Alasadi, A | 1 |
| Cao, B | 1 |
| Guo, J | 1 |
| Tao, H | 1 |
| Collantes, J | 1 |
| Tan, V | 1 |
| Su, X | 1 |
| Augeri, D | 1 |
| Jin, S | 1 |
| Penheiter, AR | 1 |
| Deelchand, DK | 1 |
| Kittelson, E | 1 |
| Damgard, SE | 1 |
| Murphy, SJ | 1 |
| O'Brien, DR | 1 |
| Bamlet, WR | 1 |
| Passow, MR | 1 |
| Smyrk, TC | 1 |
| Couch, FJ | 1 |
| Vasmatzis, G | 1 |
| Port, JD | 1 |
| Marjańska, M | 1 |
| Carlson, SK | 1 |
| Dutta, P | 1 |
| Perez, MR | 1 |
| Lee, J | 1 |
| Kang, Y | 1 |
| Pratt, M | 1 |
| Salzillo, TC | 1 |
| Weygand, J | 1 |
| Zacharias, NM | 1 |
| Gammon, ST | 1 |
| Koay, EJ | 1 |
| Kim, M | 1 |
| McAllister, F | 1 |
| Sen, S | 1 |
| Maitra, A | 1 |
| Piwnica-Worms, D | 1 |
| Fleming, JB | 1 |
| Bhattacharya, PK | 1 |
| Serrao, EM | 1 |
| Kettunen, MI | 1 |
| Rodrigues, TB | 1 |
| Dzien, P | 1 |
| Wright, AJ | 1 |
| Gopinathan, A | 1 |
| Gallagher, FA | 1 |
| Lewis, DY | 1 |
| Frese, KK | 1 |
| Almeida, J | 1 |
| Howat, WJ | 1 |
| Tuveson, DA | 1 |
| Brindle, KM | 1 |
7 other studies available for pyruvic acid and Carcinoma, Pancreatic Ductal
| Article | Year |
|---|---|
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
Topics: Animals; Aspartate Aminotransferase, Mitochondrial; Carcinoma, Pancreatic Ductal; Fatty Acid-Binding | 2022 |
Integrated transcriptomics, proteomics and metabolomics-based analysis uncover TAM2-associated glycolysis and pyruvate metabolic remodeling in pancreatic cancer.
Topics: Carcinoma, Pancreatic Ductal; Glycolysis; Humans; Metabolomics; Pancreatic Neoplasms; Proteomics; Py | 2023 |
PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis.
Topics: Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Diet, High-Fat; Drug | 2021 |
Mitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models.
Topics: Adenocarcinoma; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Car | 2021 |
Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms.
Topics: Adenocarcinoma, Mucinous; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Gen | 2018 |
Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Glycolysis; Heterografts; Humans; Hypoxia- | 2019 |
MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model.
Topics: Animals; Biomarkers; Carbon-13 Magnetic Resonance Spectroscopy; Carcinoma, Pancreatic Ductal; Diseas | 2016 |