pyruvic acid has been researched along with Carcinoma, Non-Small Cell Lung in 5 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aspirin has been reported to promote apoptosis, inhibit proliferation, stemness, angiogenesis, cancer-associated inflammation and migration in NSCLC." | 1.72 | Aspirin blocks AMPK/SIRT3-mediated glycolysis to inhibit NSCLC cell proliferation. ( Li, G; Ma, Y; Ren, G; Wang, X; Zheng, Z, 2022) |
| "Our results define a role for PCK2 in cancer cell metabolic reprogramming that promotes glucose-independent cell growth and metabolic stress resistance in human tumors." | 1.42 | Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth. ( Artyomov, MN; Avizonis, D; Blagih, J; Bridon, G; Choinière, L; Coelho, PP; Elder, DJ; Flynn, BR; Gingras, MC; Griss, T; Jones, RG; Loginicheva, E; Ntimbane, T; Pause, A; Raissi, TC; Samborska, B; Sergushichev, A; Tavaré, JM; Thomas, EC; Vincent, EE, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, G | 1 |
| Ma, Y | 1 |
| Wang, X | 2 |
| Zheng, Z | 1 |
| Li, G | 1 |
| Xie, H | 1 |
| Hanai, J | 1 |
| Ren, JG | 1 |
| Kats, L | 1 |
| Burgess, K | 1 |
| Bhargava, P | 1 |
| Signoretti, S | 1 |
| Billiard, J | 1 |
| Duffy, KJ | 1 |
| Grant, A | 1 |
| Lorkiewicz, PK | 1 |
| Schatzman, S | 1 |
| Bousamra, M | 1 |
| Lane, AN | 1 |
| Higashi, RM | 1 |
| Fan, TW | 1 |
| Pandolfi, PP | 1 |
| Sukhatme, VP | 1 |
| Seth, P | 1 |
| Ma, JJ | 1 |
| Wang, XL | 1 |
| Liu, HP | 1 |
| Vincent, EE | 1 |
| Sergushichev, A | 1 |
| Griss, T | 1 |
| Gingras, MC | 1 |
| Samborska, B | 1 |
| Ntimbane, T | 1 |
| Coelho, PP | 1 |
| Blagih, J | 1 |
| Raissi, TC | 1 |
| Choinière, L | 1 |
| Bridon, G | 1 |
| Loginicheva, E | 1 |
| Flynn, BR | 1 |
| Thomas, EC | 1 |
| Tavaré, JM | 1 |
| Avizonis, D | 1 |
| Pause, A | 1 |
| Elder, DJ | 1 |
| Artyomov, MN | 1 |
| Jones, RG | 1 |
| Davidson, SM | 1 |
| Papagiannakopoulos, T | 1 |
| Olenchock, BA | 1 |
| Heyman, JE | 1 |
| Keibler, MA | 1 |
| Luengo, A | 1 |
| Bauer, MR | 1 |
| Jha, AK | 1 |
| O'Brien, JP | 1 |
| Pierce, KA | 1 |
| Gui, DY | 1 |
| Sullivan, LB | 1 |
| Wasylenko, TM | 1 |
| Subbaraj, L | 1 |
| Chin, CR | 1 |
| Stephanopolous, G | 1 |
| Mott, BT | 1 |
| Jacks, T | 1 |
| Clish, CB | 1 |
| Vander Heiden, MG | 1 |
5 other studies available for pyruvic acid and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Aspirin blocks AMPK/SIRT3-mediated glycolysis to inhibit NSCLC cell proliferation.
Topics: AMP-Activated Protein Kinases; Aspirin; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Glycolys | 2022 |
Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.
Topics: Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell | 2014 |
[Metabolomics Study on Non-Small Cell Lung Cancer Patients with Different Chinese Medical Syndromes].
Topics: Asian People; Carcinoma, Non-Small-Cell Lung; Gas Chromatography-Mass Spectrometry; Humans; Lactic A | 2015 |
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth.
Topics: Adaptation, Physiological; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Prolifera | 2015 |
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Topics: Animals; Blood Glucose; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Glucose; Humans; Lung; Lun | 2016 |