pyruvic acid has been researched along with Cancer of Prostate in 48 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The technique was extended to polarize four 13C labelled substrates potentially providing information on pH, metabolism, necrosis and perfusion, namely [1-(13)C]pyruvic acid, 13C sodium bicarbonate, [1,4-(13)C]fumaric acid, and 13C urea with high levels of solution polarization (17." | 3.76 | Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo. ( Bok, R; Chen, AP; Hu, S; Keshari, KR; Kurhanewicz, J; Larson, PE; Macdonald, JM; Nelson, SJ; Van Criekinge, M; Vigneron, DB; Wilson, DM, 2010) |
| "30)." | 1.72 | The ubiquitous expression of pyruvate carboxylase among human prostate tumors. ( Dobrota, D; Gondas, E; Hives, M; Kliment, J; Kmetova Sivonova, M; Murin, R, 2022) |
| " In normal rats, Michaelis-Menten kinetics were able to describe the dose-response of the fitted exchange rate constants with a 13." | 1.36 | Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice. ( Albers, MJ; Bok, R; Chen, AP; Hurd, RE; Kurhanewicz, J; Nelson, SJ; Park, I; Tropp, J; Vigneron, DB; Yen, YF; Zhang, V; Zierhut, ML, 2010) |
| "Proliferating cells, including cancer cells, require altered metabolism to efficiently incorporate nutrients such as glucose into biomass." | 1.36 | Evidence for an alternative glycolytic pathway in rapidly proliferating cells. ( Amador-Noguez, D; Asara, JM; Cantley, LC; Christofk, HR; Heffron, GJ; Locasale, JW; Rabinowitz, JD; Sharfi, H; Swanson, KD; Vander Heiden, MG; Wagner, G, 2010) |
| "Prostate cancer has been shown to undergo unique metabolic changes associated with neoplastic transformation, with associated changes in citrate, alanine, and lactate concentrations." | 1.35 | Methods for metabolic evaluation of prostate cancer cells using proton and (13)C HR-MAS spectroscopy and [3-(13)C] pyruvate as a metabolic substrate. ( Albers, MJ; Butler, TN; Kurhanewicz, J; Levin, YS; Peehl, DM; Spielman, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (4.17) | 29.6817 |
| 2010's | 33 (68.75) | 24.3611 |
| 2020's | 13 (27.08) | 2.80 |
| Authors | Studies |
|---|---|
| de Kouchkovsky, I | 1 |
| Chen, HY | 8 |
| Ohliger, MA | 2 |
| Wang, ZJ | 1 |
| Bok, RA | 6 |
| Gordon, JW | 12 |
| Larson, PEZ | 10 |
| Frost, M | 1 |
| Okamoto, K | 1 |
| Cooperberg, MR | 1 |
| Kurhanewicz, J | 15 |
| Vigneron, DB | 22 |
| Aggarwal, R | 6 |
| Sushentsev, N | 1 |
| McLean, MA | 1 |
| Warren, AY | 1 |
| Brodie, C | 1 |
| Jones, J | 1 |
| Gallagher, FA | 1 |
| Barrett, T | 1 |
| Gondas, E | 1 |
| Hives, M | 1 |
| Kliment, J | 1 |
| Kmetova Sivonova, M | 1 |
| Dobrota, D | 1 |
| Murin, R | 1 |
| Clemmensen, A | 1 |
| Loft, M | 1 |
| Kjaer, A | 1 |
| Andersen, TL | 1 |
| Xu, Z | 4 |
| Michel, KA | 4 |
| Walker, CM | 4 |
| Harlan, CJ | 3 |
| Martinez, GV | 3 |
| Bankson, JA | 5 |
| Sahin, SI | 1 |
| Ji, X | 1 |
| Agarwal, S | 1 |
| Sinha, A | 1 |
| Mali, I | 1 |
| Mattingly, M | 1 |
| Subramaniam, S | 1 |
| Sriram, R | 2 |
| Granlund, KL | 2 |
| Tee, SS | 2 |
| Vargas, HA | 1 |
| Lyashchenko, SK | 1 |
| Reznik, E | 1 |
| Fine, S | 1 |
| Laudone, V | 1 |
| Eastham, JA | 1 |
| Touijer, KA | 1 |
| Reuter, VE | 1 |
| Gonen, M | 1 |
| Sosa, RE | 1 |
| Nicholson, D | 1 |
| Guo, YW | 1 |
| Chen, AP | 5 |
| Tropp, J | 3 |
| Robb, F | 1 |
| Hricak, H | 1 |
| Keshari, KR | 3 |
| Zhu, Z | 3 |
| Lee, P | 1 |
| van Criekinge, M | 5 |
| Carvajal, L | 4 |
| Slater, JB | 4 |
| Small, EJ | 2 |
| Stone, L | 1 |
| Stewart, NJ | 1 |
| Matsumoto, S | 1 |
| Qin, H | 1 |
| Zhang, V | 2 |
| Santos, RD | 1 |
| Cunha, JA | 1 |
| Hsu, IC | 1 |
| Santos Bs, JD | 1 |
| Lee, JE | 1 |
| Sukumar, S | 2 |
| Wilson, DM | 2 |
| van Heijster, FHA | 1 |
| Heskamp, S | 1 |
| Breukels, V | 2 |
| Veltien, A | 1 |
| Franssen, GM | 1 |
| Jansen, KCFJ | 1 |
| Boerman, OC | 1 |
| Schalken, JA | 2 |
| Scheenen, TWJ | 1 |
| Heerschap, A | 1 |
| Li, L | 1 |
| Milshteyn, E | 3 |
| von Morze, C | 4 |
| Ferrone, M | 4 |
| Cao, P | 1 |
| Pauly, JM | 5 |
| Kerr, AB | 5 |
| Park, I | 4 |
| Nelson, SJ | 6 |
| Munster, PN | 1 |
| Korn, N | 1 |
| Maidens, J | 2 |
| Arcak, M | 2 |
| Tang, S | 2 |
| Criekinge, M | 1 |
| Mammoli, D | 2 |
| Bok, R | 9 |
| Reed, G | 3 |
| Gordon, J | 1 |
| Zhu, X | 1 |
| Beynon, RA | 1 |
| Richmond, RC | 1 |
| Santos Ferreira, DL | 1 |
| Ness, AR | 1 |
| May, M | 1 |
| Smith, GD | 1 |
| Vincent, EE | 1 |
| Adams, C | 1 |
| Ala-Korpela, M | 1 |
| Würtz, P | 1 |
| Soidinsalo, S | 1 |
| Metcalfe, C | 1 |
| Donovan, JL | 1 |
| Lane, AJ | 1 |
| Martin, RM | 1 |
| Autry, A | 1 |
| Xu, D | 1 |
| Li, Y | 1 |
| Chang, S | 1 |
| Nelson, S | 1 |
| Bader, DA | 1 |
| Hartig, SM | 1 |
| Putluri, V | 1 |
| Foley, C | 1 |
| Hamilton, MP | 1 |
| Smith, EA | 1 |
| Saha, PK | 1 |
| Panigrahi, A | 1 |
| Walker, C | 1 |
| Zong, L | 1 |
| Martini-Stoica, H | 1 |
| Chen, R | 1 |
| Rajapakshe, K | 1 |
| Coarfa, C | 1 |
| Sreekumar, A | 1 |
| Mitsiades, N | 1 |
| Ittmann, MM | 1 |
| O'Malley, BW | 1 |
| Putluri, N | 1 |
| McGuire, SE | 1 |
| Xing, Y | 1 |
| Reed, GD | 3 |
| Larson, PE | 10 |
| Harzstark, AL | 1 |
| Chang, JW | 1 |
| Munster, P | 1 |
| Weinberg, VK | 1 |
| Ardenkjaer-Larsen, JH | 3 |
| Hurd, RE | 2 |
| Odegardstuen, LI | 1 |
| Robb, FJ | 1 |
| Murray, JA | 1 |
| Christensen, CE | 1 |
| Karlsson, M | 1 |
| Winther, JR | 1 |
| Jensen, PR | 1 |
| Lerche, MH | 1 |
| Mallett, CL | 1 |
| Lim, H | 1 |
| Thind, K | 1 |
| Chen, Y | 1 |
| Ribot, EJ | 1 |
| Martinez, F | 1 |
| Scholl, TJ | 1 |
| Foster, PJ | 1 |
| Laustsen, C | 1 |
| Pedersen, M | 1 |
| Ringgaard, S | 1 |
| Stødkilde-Jørgensen, H | 1 |
| Jansen, KC | 1 |
| van Heijster, FH | 1 |
| Capozzi, A | 1 |
| van Bentum, PJ | 1 |
| Comment, A | 1 |
| Scheenen, TW | 1 |
| Yao, ML | 1 |
| Gu, J | 1 |
| Zhang, YC | 1 |
| Wang, N | 1 |
| Zhu, ZH | 1 |
| Yang, QT | 1 |
| Liu, M | 1 |
| Xia, JF | 1 |
| Kumar, D | 1 |
| Gupta, A | 1 |
| Mandhani, A | 1 |
| Sankhwar, SN | 1 |
| DiGialleonardo, V | 1 |
| Eskandari, R | 1 |
| Jeong, S | 1 |
| Miloushev, V | 1 |
| Poot, AJ | 1 |
| Truong, S | 1 |
| Alvarez, JA | 1 |
| Aldeborgh, HN | 1 |
| Kubala, E | 1 |
| Muñoz-Álvarez, KA | 1 |
| Topping, G | 1 |
| Hundshammer, C | 1 |
| Feuerecker, B | 1 |
| Gómez, PA | 1 |
| Pariani, G | 1 |
| Schilling, F | 1 |
| Glaser, SJ | 1 |
| Schulte, RF | 1 |
| Menzel, MI | 1 |
| Schwaiger, M | 1 |
| Levin, YS | 1 |
| Albers, MJ | 2 |
| Butler, TN | 1 |
| Spielman, D | 1 |
| Peehl, DM | 1 |
| Zierhut, ML | 1 |
| Yen, YF | 1 |
| Wartenberg, M | 1 |
| Richter, M | 1 |
| Datchev, A | 1 |
| Günther, S | 1 |
| Milosevic, N | 1 |
| Bekhite, MM | 1 |
| Figulla, HR | 1 |
| Aran, JM | 1 |
| Pétriz, J | 1 |
| Sauer, H | 1 |
| Lustig, M | 2 |
| Hu, S | 4 |
| Macdonald, JM | 1 |
| Wallach, I | 1 |
| Jaitly, N | 1 |
| Lilien, R | 1 |
| Vander Heiden, MG | 1 |
| Locasale, JW | 1 |
| Swanson, KD | 1 |
| Sharfi, H | 1 |
| Heffron, GJ | 1 |
| Amador-Noguez, D | 1 |
| Christofk, HR | 1 |
| Wagner, G | 1 |
| Rabinowitz, JD | 1 |
| Asara, JM | 1 |
| Cantley, LC | 1 |
| De Bari, L | 1 |
| Chieppa, G | 1 |
| Marra, E | 1 |
| Passarella, S | 1 |
| Shin, P | 1 |
| Yoshihara, HA | 1 |
| Goga, A | 1 |
| Morze, Cv | 1 |
| Giatromanolaki, A | 1 |
| Koukourakis, MI | 1 |
| Koutsopoulos, A | 1 |
| Mendrinos, S | 1 |
| Sivridis, E | 1 |
| Lodi, A | 1 |
| Woods, SM | 1 |
| Ronen, SM | 1 |
| Swisher, CL | 1 |
| Erkkilä, K | 1 |
| Suomalainen, L | 1 |
| Wikström, M | 1 |
| Parvinen, M | 1 |
| Dunkel, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Characterization of Hyperpolarized Pyruvate MRI Reproducibility[NCT02421380] | 109 participants (Anticipated) | Interventional | 2015-04-30 | Recruiting | |||
| Effect of Fatty Liver on TCA Cycle Flux and the Pentose Phosphate Pathway (HP FFF)[NCT03480594] | 30 participants (Anticipated) | Observational | 2018-10-01 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pyruvic acid and Cancer of Prostate
| Article | Year |
|---|---|
Biomedical Applications of the Dynamic Nuclear Polarization and Parahydrogen Induced Polarization Techniques for Hyperpolarized
Topics: Carbon-13 Magnetic Resonance Spectroscopy; Humans; Male; Prostate; Prostatic Neoplasms; Pyruvic Acid | 2021 |
[Quantitative cellular metabolism can be estimated by hyperpolarized magnetic resonance].
Topics: Administration, Intravenous; Biosensing Techniques; Humans; Lactic Acid; Magnetic Resonance Imaging; | 2014 |
1 trial available for pyruvic acid and Cancer of Prostate
| Article | Year |
|---|---|
Investigating the effects of lycopene and green tea on the metabolome of men at risk of prostate cancer: The ProDiet randomised controlled trial.
Topics: Aged; Feeding Behavior; Humans; Lycopene; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabol | 2019 |
45 other studies available for pyruvic acid and Cancer of Prostate
| Article | Year |
|---|---|
Hyperpolarized 1-[
Topics: Humans; Immune Checkpoint Inhibitors; Magnetic Resonance Imaging; Male; Prostatic Neoplasms; Pyruvic | 2022 |
The potential of hyperpolarised
Topics: Humans; Lactates; Magnetic Resonance Imaging; Male; Prostatic Neoplasms; Pyruvic Acid; Tumor Burden | 2022 |
The ubiquitous expression of pyruvate carboxylase among human prostate tumors.
Topics: Humans; Male; Oxaloacetates; Prostatic Hyperplasia; Prostatic Neoplasms; Pyruvate Carboxylase; Pyruv | 2022 |
Editorial for "Quantification of Prostate Cancer Metabolism Using 3D Multiecho bSSFP and Hyperpolarized [1-
Topics: Carbon Isotopes; Humans; Magnetic Resonance Imaging; Male; Prostatic Neoplasms; Pyruvic Acid | 2023 |
Model-constrained reconstruction accelerated with Fourier-based undersampling for hyperpolarized [1-
Topics: Humans; Lactates; Magnetic Resonance Imaging; Male; Phantoms, Imaging; Prostatic Neoplasms; Pyruvic | 2023 |
Model-constrained reconstruction accelerated with Fourier-based undersampling for hyperpolarized [1-
Topics: Humans; Lactates; Magnetic Resonance Imaging; Male; Phantoms, Imaging; Prostatic Neoplasms; Pyruvic | 2023 |
Model-constrained reconstruction accelerated with Fourier-based undersampling for hyperpolarized [1-
Topics: Humans; Lactates; Magnetic Resonance Imaging; Male; Phantoms, Imaging; Prostatic Neoplasms; Pyruvic | 2023 |
Model-constrained reconstruction accelerated with Fourier-based undersampling for hyperpolarized [1-
Topics: Humans; Lactates; Magnetic Resonance Imaging; Male; Phantoms, Imaging; Prostatic Neoplasms; Pyruvic | 2023 |
Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized
Topics: Animals; Echo-Planar Imaging; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Mice; Prostatic | 2023 |
Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1.
Topics: Aged; Carbon Isotopes; Humans; Kinetics; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; | 2020 |
Hyperpolarized
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carbon Isot | 2020 |
Piloting hyperpolarized
Topics: Carbon Isotopes; Feasibility Studies; Humans; Liver; Magnetic Resonance Imaging; Male; Prostatic Neo | 2020 |
Simultaneous Metabolic and Perfusion Imaging Using Hyperpolarized
Topics: Animals; Carbon Isotopes; Disease Models, Animal; Dose-Response Relationship, Radiation; Magnetic Re | 2020 |
Pyruvate-lactate exchange and glucose uptake in human prostate cancer cell models. A study in xenografts and suspensions by hyperpolarized [1-
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Energy Metabolism; Fluorodeoxy | 2020 |
Slice profile effects on quantitative analysis of hyperpolarized pyruvate.
Topics: Area Under Curve; Computer Simulation; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Phanto | 2020 |
Hyperpolarized 1-[
Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Carbon-13 Magnetic Resonance | 2017 |
High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-
Topics: Adenocarcinoma; Alanine; Animals; Carbon Isotopes; Image Processing, Computer-Assisted; Lactic Acid; | 2018 |
Technique development of 3D dynamic CS-EPSI for hyperpolarized
Topics: Aged; Animals; Echo-Planar Imaging; Humans; Imaging, Three-Dimensional; Male; Mice; Phantoms, Imagin | 2018 |
Investigation of analysis methods for hyperpolarized 13C-pyruvate metabolic MRI in prostate cancer patients.
Topics: Area Under Curve; Carbon Isotopes; Computer Simulation; Humans; Magnetic Resonance Imaging; Male; Mi | 2018 |
A regional bolus tracking and real-time B
Topics: Adult; Algorithms; Animals; Brain Mapping; Calibration; Carbon Isotopes; Disease Models, Animal; Hea | 2019 |
Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.
Topics: Artifacts; Bicarbonates; Brain; Brain Neoplasms; Calibration; Carbon Isotopes; Carbon-13 Magnetic Re | 2019 |
Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.
Topics: Animals; Biological Transport; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, | 2019 |
Optimal variable flip angle schemes for dynamic acquisition of exchanging hyperpolarized substrates.
Topics: Adenocarcinoma; Algorithms; Animals; Biotransformation; Carbon Isotopes; Computer Simulation; Image | 2013 |
Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate.
Topics: Aged; Carbon Isotopes; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prostatic Neoplasms; P | 2013 |
Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Glucose; Glycolysis; Humans; Lactic Acid; Male; NAD; Pro | 2014 |
Longitudinal anatomical and metabolic MRI characterization of orthotopic xenograft prostate tumors in nude mice.
Topics: Animals; Carbon Isotopes; Cell Line, Tumor; Computer Simulation; Contrast Media; Humans; Image Inter | 2014 |
Direct dynamic measurement of intracellular and extracellular lactate in small-volume cell suspensions with (13)C hyperpolarised NMR.
Topics: Biological Transport; Carbon-13 Magnetic Resonance Spectroscopy; Cell Count; Cell Line, Tumor; Extra | 2015 |
[Inhibitory effect of Genipin on uncoupling protein-2 and energy metabolism of androgen-independent prostate cancer cells].
Topics: Cell Line, Tumor; Energy Metabolism; Humans; Ion Channels; Iridoids; Male; Mitochondria; Mitochondri | 2015 |
NMR spectroscopy of filtered serum of prostate cancer: A new frontier in metabolomics.
Topics: Aged; Biomarkers, Tumor; Biopsy; Citric Acid; Diagnosis, Differential; Digital Rectal Examination; G | 2016 |
Optimizing Flip Angles for Metabolic Rate Estimation in Hyperpolarized Carbon-13 MRI.
Topics: Algorithms; Animals; Carbon Isotopes; Computer Simulation; Disease Models, Animal; Image Processing, | 2016 |
Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field.
Topics: Animals; Antibiotics, Antineoplastic; Humans; Lactic Acid; Magnetic Fields; Magnetic Resonance Imagi | 2016 |
Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging.
Topics: Cell Line, Tumor; Fluorodeoxyglucose F18; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic | 2016 |
Methods for metabolic evaluation of prostate cancer cells using proton and (13)C HR-MAS spectroscopy and [3-(13)C] pyruvate as a metabolic substrate.
Topics: Biomarkers; Carbon Radioisotopes; Humans; Magnetic Resonance Spectroscopy; Male; Prostatic Neoplasms | 2009 |
Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice.
Topics: Alanine; Algorithms; Animals; Carbon Isotopes; Computer Simulation; Kinetics; Lactic Acid; Magnetic | 2010 |
Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1 | 2010 |
Investigation of tumor hyperpolarized [1-13C]-pyruvate dynamics using time-resolved multiband RF excitation echo-planar MRSI.
Topics: Animals; Carbon Isotopes; Echo-Planar Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Tr | 2010 |
Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo.
Topics: Animals; Biomarkers, Tumor; Enzymes; Fumarates; Gadolinium; Hydrogen-Ion Concentration; Indicators a | 2010 |
A structure-based approach for mapping adverse drug reactions to the perturbation of underlying biological pathways.
Topics: Breast Neoplasms; Computational Biology; Databases, Factual; Diabetes Mellitus, Type 2; Drug-Related | 2010 |
Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Line, Tumor; Cell Proliferation; Female; Glucose; G | 2010 |
L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase.
Topics: Carcinoma; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Humans; L-Lactate Dehydrogena | 2010 |
Multi-band frequency encoding method for metabolic imaging with hyperpolarized [1-(13)C]pyruvate.
Topics: Alanine; Algorithms; Animals; Carbon Isotopes; Computer Simulation; Image Processing, Computer-Assis | 2011 |
Investigating tumor perfusion and metabolism using multiple hyperpolarized (13)C compounds: HP001, pyruvate and urea.
Topics: Animals; Carbon Isotopes; Contrast Media; Cyclopropanes; Disease Models, Animal; Imaging, Three-Dime | 2012 |
A method for simultaneous echo planar imaging of hyperpolarized ¹³C pyruvate and ¹³C lactate.
Topics: Animals; Carbon Isotopes; Cell Line, Tumor; Echo-Planar Imaging; Lactic Acid; Male; Mice; Mice, Tran | 2012 |
The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer.
Topics: Adult; Aged; Aged, 80 and over; Caveolin 1; Cell Communication; Cell Proliferation; Fibroblasts; Hum | 2012 |
Frequency-specific SSFP for hyperpolarized ¹³C metabolic imaging at 14.1 T.
Topics: Animals; Carbon Isotopes; Computer Simulation; Humans; Magnetic Resonance Imaging; Male; Mice; Model | 2013 |
Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells.
Topics: Breast Neoplasms; Butadienes; Cell Line, Tumor; Female; Humans; Lactic Acid; Male; MCF-7 Cells; Mito | 2013 |
A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates.
Topics: Adenocarcinoma; Algorithms; Animals; Electromagnetic Fields; Humans; Kinetics; L-Lactate Dehydrogena | 2012 |
Chemical anoxia delays germ cell apoptosis in the human testis.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aged; Antimetabolites; Apopt | 2003 |