pyruvic acid has been researched along with Cancer of Ovary in 4 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "less invasive ovarian cancer cells in detachment." | 1.38 | Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration. ( Bellance, N; Caneba, CA; Nagrath, D; Pabst, L; Yang, L, 2012) |
| "Eight ovarian cancer cell lines were tested (SKOV3, CAOV3, OVCAR3, OVCAR10, A2780, CP70, C30, and C200) and showed IC50s for EGCG at the micromolar range, including ones that are resistant to the chemotherapeutic drug cisplatin." | 1.33 | Epigallocatechin-3-gallate delivers hydrogen peroxide to induce death of ovarian cancer cells and enhances their cisplatin susceptibility. ( Chan, MM; Fong, D; Soprano, KJ; Weinstein, K, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, Y | 1 |
| Zhang, X | 1 |
| Zhang, S | 1 |
| Xu, S | 1 |
| Chen, X | 1 |
| Zhou, C | 1 |
| Xi, Y | 1 |
| Xie, X | 1 |
| Lu, W | 1 |
| Nonomiya, Y | 1 |
| Noguchi, K | 1 |
| Katayama, K | 1 |
| Sugimoto, Y | 1 |
| Caneba, CA | 1 |
| Bellance, N | 1 |
| Yang, L | 1 |
| Pabst, L | 1 |
| Nagrath, D | 1 |
| Chan, MM | 1 |
| Soprano, KJ | 1 |
| Weinstein, K | 1 |
| Fong, D | 1 |
4 other studies available for pyruvic acid and Cancer of Ovary
| Article | Year |
|---|---|
PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells.
Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Glycolysis; Humans; Lactic Acid; Ovarian Neopla | 2022 |
Novel pharmacological effects of poly (ADP-ribose) polymerase inhibitor rucaparib on the lactate dehydrogenase pathway.
Topics: Cell Line, Tumor; Female; Humans; Indoles; L-Lactate Dehydrogenase; Lactic Acid; Ovarian Neoplasms; | 2019 |
Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration.
Topics: Adenosine Triphosphate; Amino Acids; Anoikis; Cell Line, Tumor; Cell Movement; Cell Survival; Citric | 2012 |
Epigallocatechin-3-gallate delivers hydrogen peroxide to induce death of ovarian cancer cells and enhances their cisplatin susceptibility.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2006 |