pyruvic acid has been researched along with Breast Cancer in 42 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2‑Deoxyglucose (2‑DG) was more cytotoxic in CT26 cancer cells compared with T47D cells, despite a smaller suppression of glucose uptake." | 5.56 | Troglitazone exerts metabolic and antitumor effects on T47D breast cancer cells by suppressing mitochondrial pyruvate availability. ( Cho, YS; Jung, KH; Lee, JH; Lee, KH; Moon, SH; Park, JW, 2020) |
| "The kinetic mechanism of the cytosolic NADP(+)-dependent malic enzyme from cultured human breast cancer cell line was studied by steady-state kinetics." | 3.68 | Kinetic mechanism of the cytosolic malic enzyme from human breast cancer cell line. ( Chang, GG; Chou, WY; Huang, TM; Lee, HJ; Meng, CL; Wang, JK, 1992) |
| "The first-line treatment of metastatic breast cancer in premenopausal women relies on tamoxifen." | 1.72 | Lactate and pyruvate levels correlation with lactate dehydrogenase gene expression and glucose consumption in Tamoxifen-resistant MCF-7 cells using capillary electrophoresis with contactless conductivity detection (CE-C ( Albustanji, S; Alhusban, AA; Hamadneh, LA; Shallan, AI, 2022) |
| "2‑Deoxyglucose (2‑DG) was more cytotoxic in CT26 cancer cells compared with T47D cells, despite a smaller suppression of glucose uptake." | 1.56 | Troglitazone exerts metabolic and antitumor effects on T47D breast cancer cells by suppressing mitochondrial pyruvate availability. ( Cho, YS; Jung, KH; Lee, JH; Lee, KH; Moon, SH; Park, JW, 2020) |
| "Human breast tumors contain significant amounts of stromal cells." | 1.46 | Tumor stroma interaction is mediated by monocarboxylate metabolism. ( Ackerstaff, E; Banerjee, D; Blasberg, RG; Kerrigan, JE; Koutcher, JA; Patel, BB; Serganova, IS, 2017) |
| "In mouse models of human melanoma and breast cancer, we were able to detect the metabolic differences among tumors of different metastatic potential and between normal and cancer tissues by optical imaging of the mitochondrial redox state of snap-frozen tissue samples." | 1.39 | In vivo metabolic evaluation of breast tumor mouse xenografts for predicting aggressiveness using the hyperpolarized (13)C-NMR technique. ( Cai, K; Hariharan, H; Kadlececk, S; Li, LZ; Profka, H; Pullinger, B; Rizi, R; Xu, HN, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.76) | 18.7374 |
| 1990's | 3 (7.14) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 26 (61.90) | 24.3611 |
| 2020's | 10 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Alhusban, AA | 1 |
| Hamadneh, LA | 1 |
| Albustanji, S | 1 |
| Shallan, AI | 1 |
| Kim, SH | 2 |
| Singh, SV | 1 |
| Arponen, O | 1 |
| Wodtke, P | 1 |
| Gallagher, FA | 2 |
| Woitek, R | 1 |
| Jung, KH | 1 |
| Lee, JH | 1 |
| Park, JW | 1 |
| Moon, SH | 1 |
| Cho, YS | 1 |
| Lee, KH | 1 |
| Becker, LM | 1 |
| O'Connell, JT | 1 |
| Vo, AP | 1 |
| Cain, MP | 1 |
| Tampe, D | 1 |
| Bizarro, L | 1 |
| Sugimoto, H | 1 |
| McGow, AK | 1 |
| Asara, JM | 1 |
| Lovisa, S | 1 |
| McAndrews, KM | 1 |
| Zielinski, R | 1 |
| Lorenzi, PL | 1 |
| Zeisberg, M | 1 |
| Raza, S | 1 |
| LeBleu, VS | 1 |
| Kalluri, R | 1 |
| Park, JM | 1 |
| Reed, GD | 1 |
| Liticker, J | 1 |
| Putnam, WC | 1 |
| Chandra, A | 1 |
| Yaros, K | 1 |
| Afzal, A | 1 |
| MacNamara, J | 1 |
| Raza, J | 1 |
| Hall, RG | 1 |
| Baxter, J | 1 |
| Derner, K | 1 |
| Pena, S | 1 |
| Kallem, RR | 1 |
| Subramaniyan, I | 1 |
| Edpuganti, V | 1 |
| Harrison, CE | 1 |
| Muthukumar, A | 1 |
| Lewis, C | 1 |
| Reddy, S | 1 |
| Unni, N | 1 |
| Klemow, D | 1 |
| Syed, S | 1 |
| Li, H | 1 |
| Cole, S | 1 |
| Froehlich, T | 1 |
| Ayers, C | 1 |
| de Lemos, J | 1 |
| Malloy, CR | 1 |
| Haley, B | 1 |
| Zaha, VG | 1 |
| Makrecka-Kuka, M | 1 |
| Dimitrijevs, P | 1 |
| Domracheva, I | 1 |
| Jaudzems, K | 1 |
| Dambrova, M | 1 |
| Arsenyan, P | 1 |
| Rinaldi, G | 1 |
| Pranzini, E | 1 |
| Van Elsen, J | 1 |
| Broekaert, D | 3 |
| Funk, CM | 1 |
| Planque, M | 1 |
| Doglioni, G | 2 |
| Altea-Manzano, P | 1 |
| Rossi, M | 2 |
| Geldhof, V | 1 |
| Teoh, ST | 1 |
| Ross, C | 1 |
| Hunter, KW | 1 |
| Lunt, SY | 1 |
| Grünewald, TGP | 1 |
| Fendt, SM | 3 |
| Varma, G | 1 |
| Seth, P | 1 |
| Coutinho de Souza, P | 1 |
| Callahan, C | 1 |
| Pinto, J | 1 |
| Vaidya, M | 1 |
| Sonzogni, O | 1 |
| Sukhatme, V | 1 |
| Wulf, GM | 1 |
| Grant, AK | 1 |
| Ros, S | 1 |
| Wright, AJ | 1 |
| Bruna, A | 1 |
| Caldas, C | 1 |
| Brindle, KM | 2 |
| Schneider, SS | 1 |
| Henchey, EM | 1 |
| Sultana, N | 1 |
| Morin, SM | 1 |
| Jerry, DJ | 1 |
| Makari-Judson, G | 1 |
| Crisi, GM | 1 |
| Arenas, RB | 1 |
| Johnson, M | 1 |
| Mason, HS | 1 |
| Yadava, N | 1 |
| Shinde, A | 1 |
| Wilmanski, T | 1 |
| Chen, H | 1 |
| Teegarden, D | 1 |
| Wendt, MK | 1 |
| Eastlack, SC | 1 |
| Dong, S | 1 |
| Ivan, C | 1 |
| Alahari, SK | 1 |
| De Castro, F | 1 |
| Benedetti, M | 1 |
| Antonaci, G | 1 |
| Del Coco, L | 1 |
| De Pascali, SA | 1 |
| Muscella, A | 1 |
| Marsigliante, S | 1 |
| Fanizzi, FP | 1 |
| Elia, I | 2 |
| Stegen, S | 1 |
| van Gorsel, M | 1 |
| Boon, R | 1 |
| Escalona-Noguero, C | 1 |
| Torrekens, S | 1 |
| Verfaillie, C | 1 |
| Verbeken, E | 1 |
| Carmeliet, G | 1 |
| Zhu, Z | 1 |
| Zhu, X | 1 |
| Ohliger, MA | 1 |
| Tang, S | 1 |
| Cao, P | 1 |
| Carvajal, L | 1 |
| Autry, AW | 1 |
| Li, Y | 1 |
| Kurhanewicz, J | 1 |
| Chang, S | 1 |
| Aggarwal, R | 1 |
| Munster, P | 1 |
| Xu, D | 1 |
| Larson, PEZ | 1 |
| Vigneron, DB | 1 |
| Gordon, JW | 1 |
| Harjes, U | 1 |
| Adler-Levy, Y | 1 |
| Nardi-Schreiber, A | 1 |
| Harris, T | 2 |
| Shaul, D | 1 |
| Uppala, S | 1 |
| Sapir, G | 1 |
| Lev-Cohain, N | 1 |
| Sosna, J | 1 |
| Goldberg, SN | 1 |
| Gomori, JM | 1 |
| Katz-Brull, R | 1 |
| Park, S | 1 |
| Safi, R | 1 |
| Liu, X | 1 |
| Baldi, R | 1 |
| Liu, W | 1 |
| Liu, J | 1 |
| Locasale, JW | 1 |
| Chang, CY | 1 |
| McDonnell, DP | 1 |
| Chen, AP | 2 |
| Chu, W | 1 |
| Gu, YP | 2 |
| Cunningham, CH | 2 |
| Cunnhingham, CH | 1 |
| Xu, HN | 2 |
| Kadlececk, S | 2 |
| Pullinger, B | 1 |
| Profka, H | 2 |
| Cai, K | 1 |
| Hariharan, H | 1 |
| Rizi, R | 2 |
| Li, LZ | 2 |
| Christensen, CE | 1 |
| Karlsson, M | 1 |
| Winther, JR | 1 |
| Jensen, PR | 1 |
| Lerche, MH | 1 |
| Glickson, JD | 1 |
| Garrido, P | 1 |
| Osorio, FG | 1 |
| Morán, J | 1 |
| Cabello, E | 1 |
| Alonso, A | 1 |
| Freije, JM | 1 |
| González, C | 1 |
| Hong, CS | 1 |
| Graham, NA | 1 |
| Gu, W | 1 |
| Espindola Camacho, C | 1 |
| Mah, V | 1 |
| Maresh, EL | 1 |
| Alavi, M | 1 |
| Bagryanova, L | 1 |
| Krotee, PAL | 1 |
| Gardner, BK | 1 |
| Behbahan, IS | 1 |
| Horvath, S | 1 |
| Chia, D | 1 |
| Mellinghoff, IK | 1 |
| Hurvitz, SA | 1 |
| Dubinett, SM | 1 |
| Critchlow, SE | 1 |
| Kurdistani, SK | 1 |
| Goodglick, L | 1 |
| Braas, D | 1 |
| Graeber, TG | 1 |
| Christofk, HR | 1 |
| Lau, JY | 1 |
| Christen, S | 1 |
| Lorendeau, D | 1 |
| Schmieder, R | 1 |
| Metzger, K | 1 |
| Veys, K | 1 |
| Buescher, JM | 1 |
| Orth, MF | 1 |
| Davidson, SM | 1 |
| Grünewald, TG | 1 |
| De Bock, K | 1 |
| Phannasil, P | 1 |
| Ansari, IH | 1 |
| El Azzouny, M | 1 |
| Longacre, MJ | 1 |
| Rattanapornsompong, K | 1 |
| Burant, CF | 1 |
| MacDonald, MJ | 1 |
| Jitrapakdee, S | 1 |
| Neveu, MA | 1 |
| De Preter, G | 1 |
| Joudiou, N | 1 |
| Bol, A | 1 |
| Brender, JR | 1 |
| Saito, K | 1 |
| Kishimoto, S | 1 |
| Grégoire, V | 1 |
| Jordan, BF | 1 |
| Krishna, MC | 1 |
| Feron, O | 1 |
| Gallez, B | 1 |
| Patel, BB | 1 |
| Ackerstaff, E | 1 |
| Serganova, IS | 1 |
| Kerrigan, JE | 1 |
| Blasberg, RG | 1 |
| Koutcher, JA | 1 |
| Banerjee, D | 1 |
| Eliyahu, G | 1 |
| Frydman, L | 1 |
| Degani, H | 1 |
| Faria, A | 1 |
| Pestana, D | 1 |
| Teixeira, D | 1 |
| de Freitas, V | 1 |
| Mateus, N | 1 |
| Calhau, C | 1 |
| Wallach, I | 1 |
| Jaitly, N | 1 |
| Lilien, R | 1 |
| Witney, TH | 1 |
| Kettunen, MI | 1 |
| Hu, DE | 1 |
| Bohndiek, SE | 1 |
| Napolitano, R | 1 |
| Yu, WS | 1 |
| Jeong, SJ | 1 |
| Kim, JH | 1 |
| Lee, HJ | 3 |
| Song, HS | 1 |
| Kim, MS | 1 |
| Ko, E | 1 |
| Khil, JH | 1 |
| Jang, HJ | 1 |
| Kim, YC | 1 |
| Bae, H | 1 |
| Chen, CY | 1 |
| Diers, AR | 1 |
| Broniowska, KA | 1 |
| Chang, CF | 1 |
| Hogg, N | 1 |
| Lodi, A | 1 |
| Woods, SM | 1 |
| Ronen, SM | 1 |
| Lehoux, JG | 1 |
| Kandalaft, N | 1 |
| Belisle, S | 1 |
| Bellabarba, D | 1 |
| Benard, B | 1 |
| Lefebvre, A | 1 |
| Singer, S | 1 |
| Souza, K | 1 |
| Thilly, WG | 1 |
| Li, JJ | 1 |
| Oberley, LW | 1 |
| St Clair, DK | 1 |
| Ridnour, LA | 1 |
| Oberley, TD | 1 |
| Chang, GG | 1 |
| Huang, TM | 1 |
| Wang, JK | 1 |
| Chou, WY | 1 |
| Meng, CL | 1 |
| O'Donnell-Tormey, J | 1 |
| Nathan, CF | 1 |
| Lanks, K | 1 |
| DeBoer, CJ | 1 |
| de la Harpe, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. A Phase I, Double Blind, Placebo Controlled, Safety Study.[NCT00332215] | Phase 1 | 70 participants (Anticipated) | Interventional | 2006-02-28 | Terminated (stopped due to Dr. Milla has left University of Minnesota. The study is no longer being conducted at this site.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyruvic acid and Breast Cancer
| Article | Year |
|---|---|
Hyperpolarised
Topics: Breast; Breast Neoplasms; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid | 2023 |
41 other studies available for pyruvic acid and Breast Cancer
| Article | Year |
|---|---|
Lactate and pyruvate levels correlation with lactate dehydrogenase gene expression and glucose consumption in Tamoxifen-resistant MCF-7 cells using capillary electrophoresis with contactless conductivity detection (CE-C
Topics: Breast Neoplasms; Electric Conductivity; Electrophoresis, Capillary; Female; Gene Expression; Glucos | 2022 |
The FoxQ1 transcription factor is a novel regulator of electron transport chain complex I subunits in human breast cancer cells.
Topics: Adenosine Triphosphate; Breast Neoplasms; Electron Transport; Electron Transport Complex I; Female; | 2022 |
Troglitazone exerts metabolic and antitumor effects on T47D breast cancer cells by suppressing mitochondrial pyruvate availability.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyg | 2020 |
Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer.
Topics: Actins; Animals; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Line, Tumor; Epigenomics; Fem | 2020 |
Effect of Doxorubicin on Myocardial Bicarbonate Production From Pyruvate Dehydrogenase in Women With Breast Cancer.
Topics: Adult; Antibiotics, Antineoplastic; Bicarbonates; Breast Neoplasms; Carbon-13 Magnetic Resonance Spe | 2020 |
Fused isoselenazolium salts suppress breast cancer cell growth by dramatic increase in pyruvate-dependent mitochondrial ROS production.
Topics: Animals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Fibroblasts; Humans; MC | 2020 |
In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition.
Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Prolif | 2021 |
Visualizing the effects of lactate dehydrogenase (LDH) inhibition and LDH-A genetic ablation in breast and lung cancer with hyperpolarized pyruvate NMR.
Topics: Animals; BRCA1 Protein; Breast Neoplasms; Female; Gene Deletion; Lactate Dehydrogenase 5; Lung Neopl | 2021 |
Metabolic imaging with hyperpolarized [1-
Topics: Animals; Breast Neoplasms; Carbon Isotopes; Disease Models, Animal; Female; Heterografts; Humans; Ma | 2021 |
Individual-specific variation in the respiratory activities of HMECs and their bioenergetic response to IGF1 and TNFα.
Topics: Adult; Aged; Breast Neoplasms; Cell Respiration; Energy Metabolism; Epithelial Cells; Female; Humans | 2017 |
Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Female; Glucose; | 2018 |
Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Down-Regulation; Female; Gene E | 2018 |
Response of Cisplatin Resistant Skov-3 Cells to [Pt(
Topics: Breast Neoplasms; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Cell Survival | 2018 |
Breast cancer cells rely on environmental pyruvate to shape the metastatic niche.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Collagen; Disease Models, Animal; Enzyme Activation; Ex | 2019 |
Coil combination methods for multi-channel hyperpolarized
Topics: Algorithms; Breast Neoplasms; Carbon Isotopes; Computer Simulation; Electromagnetic Fields; Female; | 2019 |
Renovation in progress.
Topics: Breast Neoplasms; Humans; Pyruvic Acid | 2019 |
In-cell determination of Lactate Dehydrogenase Activity in a Luminal Breast Cancer Model ⁻
Topics: Animals; Breast Neoplasms; Cell Nucleus; Cell Polarity; Drug Liberation; Female; Humans; Lactate Deh | 2019 |
Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; ERRalpha Estrogen-Related Re | 2019 |
Probing early tumor response to radiation therapy using hyperpolarized [1-¹³C]pyruvate in MDA-MB-231 xenografts.
Topics: Animals; Apoptosis; Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Cell Transformation, N | 2013 |
In vivo metabolic evaluation of breast tumor mouse xenografts for predicting aggressiveness using the hyperpolarized (13)C-NMR technique.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Diagnostic Imaging; Female; Heterogr | 2013 |
Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Glucose; Glycolysis; Humans; Lactic Acid; Male; NAD; Pro | 2014 |
Is higher lactate an indicator of tumor metastatic risk? A pilot MRS study using hyperpolarized (13)C-pyruvate.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Humans; Lactic | 2014 |
Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cells.
Topics: Apoptosis; Biological Transport; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Proliferatio | 2015 |
MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Proli | 2016 |
Voxel-by-voxel correlations of perfusion, substrate, and metabolite signals in dynamic hyperpolarized (13) C imaging.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, | 2016 |
Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis.
Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Breast Neoplasms; Carbon Isotopes; | 2016 |
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Pr | 2017 |
Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Carcinoma, Squam | 2016 |
Tumor stroma interaction is mediated by monocarboxylate metabolism.
Topics: Autocrine Communication; Breast Neoplasms; Carbon Radioisotopes; Cell Communication; Cells, Cultured | 2017 |
Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells.
Topics: Biological Transport; Breast Neoplasms; Carbon Isotopes; Cell Hypoxia; Cell Survival; Humans; Kineti | 2009 |
Blueberry anthocyanins and pyruvic acid adducts: anticancer properties in breast cancer cell lines.
Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Blueberry Plants; Breast Neoplasms; Caspase 3; Cell | 2010 |
A structure-based approach for mapping adverse drug reactions to the perturbation of underlying biological pathways.
Topics: Breast Neoplasms; Computational Biology; Databases, Factual; Diabetes Mellitus, Type 2; Drug-Related | 2010 |
Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Calcium Dobesilate; Carbon Isotopes; Cell Death; Cell Lin | 2010 |
The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: molecular target on cancer metabolism.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drugs, Chinese H | 2011 |
Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Coumaric Acids; Female; Hu | 2012 |
Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells.
Topics: Breast Neoplasms; Butadienes; Cell Line, Tumor; Female; Humans; Lactic Acid; Male; MCF-7 Cells; Mito | 2013 |
Increased 3-hydroxy-3-methyl-glutaryl coenzyme A reductase activity in a virilizing adrenal carcinoma.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Breast Neoplasms; Carbo | 1984 |
Pyruvate utilization, phosphocholine and adenosine triphosphate (ATP) are markers of human breast tumor progression: a 31P- and 13C-nuclear magnetic resonance (NMR) spectroscopy study.
Topics: Adenosine Triphosphate; Biomarkers; Breast Neoplasms; Citric Acid Cycle; Female; Humans; Magnetic Re | 1995 |
Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase.
Topics: Animals; Base Sequence; Breast Neoplasms; Cell Division; Female; Humans; Mice; Mice, Nude; Molecular | 1995 |
Kinetic mechanism of the cytosolic malic enzyme from human breast cancer cell line.
Topics: Animals; Breast Neoplasms; Carbon Dioxide; Columbidae; Cytosol; Enzyme Stability; Humans; Kinetics; | 1992 |
Secretion of pyruvate. An antioxidant defense of mammalian cells.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line; Cell Survival; Connective Tissue; Fibroblasts; | 1987 |