pyruvic acid has been researched along with Brain Infarction in 4 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rats that were exposed to permanent middle cerebral artery occlusion (MCAO) and treated with intravenous 250 mg/kg pyruvate had a smaller volume of infarction and reduced brain edema, resulting in an improved neurological outcome and reduced mortality compared to control rats treated with saline." | 1.37 | Pyruvate's blood glutamate scavenging activity contributes to the spectrum of its neuroprotective mechanisms in a rat model of stroke. ( Boyko, M; Gruenbaum, BF; Gruenbaum, SE; Kuts, R; Melamed, I; Ohayon, S; Regev, A; Shapira, Y; Teichberg, VI; Zlotnik, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bøgh, N | 1 |
| Olin, RB | 1 |
| Hansen, ES | 1 |
| Gordon, JW | 1 |
| Bech, SK | 1 |
| Bertelsen, LB | 1 |
| Sánchez-Heredia, JD | 1 |
| Blicher, JU | 1 |
| Østergaard, L | 1 |
| Ardenkjær-Larsen, JH | 1 |
| Bok, RA | 1 |
| Vigneron, DB | 1 |
| Laustsen, C | 1 |
| Martín, A | 1 |
| Rojas, S | 1 |
| Pérez-Asensio, F | 1 |
| Planas, AM | 1 |
| Boyko, M | 1 |
| Zlotnik, A | 1 |
| Gruenbaum, BF | 1 |
| Gruenbaum, SE | 1 |
| Ohayon, S | 1 |
| Kuts, R | 1 |
| Melamed, I | 1 |
| Regev, A | 1 |
| Shapira, Y | 1 |
| Teichberg, VI | 1 |
| Zhang, J | 1 |
| Deng, Z | 1 |
| Liao, J | 1 |
| Song, C | 1 |
| Liang, C | 1 |
| Xue, H | 1 |
| Wang, L | 1 |
| Zhang, K | 1 |
| Yan, G | 1 |
4 other studies available for pyruvic acid and Brain Infarction
| Article | Year |
|---|---|
Metabolic MRI with hyperpolarized [1-
Topics: Animals; Brain; Brain Infarction; Case-Control Studies; Cerebrovascular Circulation; Endothelin-1; F | 2021 |
Transient benefits but lack of protection by sodium pyruvate after 2-hour middle cerebral artery occlusion in the rat.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Brain Infarction; Disease Models, Animal; Inf | 2009 |
Pyruvate's blood glutamate scavenging activity contributes to the spectrum of its neuroprotective mechanisms in a rat model of stroke.
Topics: Animals; Aspartate Aminotransferases; Brain Edema; Brain Infarction; Disease Models, Animal; Dose-Re | 2011 |
Leptin attenuates cerebral ischemia injury through the promotion of energy metabolism via the PI3K/Akt pathway.
Topics: Animals; Brain Edema; Brain Infarction; Chromones; Energy Metabolism; Enzyme Inhibitors; L-Lactate D | 2013 |