pyruvic acid has been researched along with Brain Disorders in 22 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients with mitochondrial encephalopathy with lactic acidosis and stroke-like episodes demonstrated only minor changes in redox state and in the behavior of the mitochondrial respiratory chain." | 3.68 | The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lacticacidemia. ( Capaldi, R; Chow, W; Glerum, DM; Lightowlers, R; Petrova-Benedict, R; Robinson, BH, 1990) |
| " We suggest that activated leukocytes consume CSF glucose and produce lactic acid and secrete protons, which causes the CSF and interstitial acidosis." | 3.67 | Brain acidosis in experimental pneumococcal meningitis. ( Andersen, NE; Gyring, J; Hansen, AJ; Laursen, H; Siesjö, BK, 1989) |
| "This review focuses on the brain and on cancer." | 2.53 | Monocarboxylate transporters in the brain and in cancer. ( Falces, J; Payen, VL; Pellerin, L; Pérez-Escuredo, J; Sboarina, M; Sonveaux, P; Van Hée, VF, 2016) |
| "Heatstroke is characterized by hyperthermia, vasoplegic shock, and cerebral ischemia and hypoxia." | 1.33 | Resuscitation from experimental heatstroke by hyperbaric oxygen therapy. ( Gao, CJ; Li, WX; Lin, MT; Niu, KC; Tsai, HM, 2005) |
| "To study intracranial cestodal cysts using in vivo proton magnetic resonance spectroscopy ((1)H MRS) in an effort to identify metabolite(s) that may help in recognizing the parasitic etiology and, perhaps, viability of such tapeworm cysts." | 1.32 | Pyruvate: an in vivo marker of cestodal infestation of the human brain on proton MR spectroscopy. ( Anandh, B; Chandrashekar, HS; Jayakumar, PN; Kovoor, JM; Shankar, SK; Srikanth, SG, 2003) |
| "During hypoxemia, both the pretreatment with endotoxin and nicotine induced higher levels of extracellular lactate and peak lactate/pyruvate ratio compared with controls (54." | 1.31 | Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia. ( Amerio, G; Frøen, JF; Saugstad, OD; Stray-Pedersen, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (36.36) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhumadilov, A | 1 |
| Boyko, M | 1 |
| Gruenbaum, SE | 1 |
| Brotfain, E | 1 |
| Bilotta, F | 1 |
| Zlotnik, A | 1 |
| Pérez-Escuredo, J | 1 |
| Van Hée, VF | 1 |
| Sboarina, M | 1 |
| Falces, J | 1 |
| Payen, VL | 1 |
| Pellerin, L | 1 |
| Sonveaux, P | 1 |
| Marcoux, J | 1 |
| McArthur, DA | 1 |
| Miller, C | 1 |
| Glenn, TC | 1 |
| Villablanca, P | 1 |
| Martin, NA | 1 |
| Hovda, DA | 1 |
| Alger, JR | 1 |
| Vespa, PM | 1 |
| Nagel, A | 1 |
| Graetz, D | 1 |
| Schink, T | 1 |
| Frieler, K | 1 |
| Sakowitz, O | 1 |
| Vajkoczy, P | 1 |
| Sarrafzadeh, A | 1 |
| Frøen, JF | 1 |
| Amerio, G | 1 |
| Stray-Pedersen, B | 1 |
| Saugstad, OD | 1 |
| BRADLEY, PL | 1 |
| HEYCK, H | 1 |
| Jayakumar, PN | 1 |
| Srikanth, SG | 1 |
| Chandrashekar, HS | 1 |
| Kovoor, JM | 1 |
| Shankar, SK | 1 |
| Anandh, B | 1 |
| Chawla, S | 1 |
| Kumar, S | 1 |
| Gupta, RK | 1 |
| Tsai, HM | 1 |
| Gao, CJ | 1 |
| Li, WX | 1 |
| Lin, MT | 1 |
| Niu, KC | 1 |
| Hansen, TL | 1 |
| Christensen, E | 1 |
| Brandt, NJ | 1 |
| Dotti, MT | 1 |
| Manneschi, L | 1 |
| Federico, A | 1 |
| Erecińska, M | 1 |
| Nelson, D | 1 |
| Hiraoka, A | 1 |
| Akai, J | 1 |
| Tominaga, I | 1 |
| Hattori, M | 1 |
| Sasaki, H | 1 |
| Arato, T | 1 |
| Engidawork, E | 1 |
| Chen, Y | 1 |
| Dell'Anna, E | 1 |
| Goiny, M | 1 |
| Lubec, G | 1 |
| Ungerstedt, U | 1 |
| Andersson, K | 1 |
| Herrera-Marschitz, M | 1 |
| Szutowicz, A | 1 |
| Tomaszewicz, M | 1 |
| Bielarczyk, H | 1 |
| Robinson, BH | 1 |
| Glerum, DM | 1 |
| Chow, W | 1 |
| Petrova-Benedict, R | 1 |
| Lightowlers, R | 1 |
| Capaldi, R | 1 |
| Andersen, NE | 1 |
| Gyring, J | 1 |
| Hansen, AJ | 1 |
| Laursen, H | 1 |
| Siesjö, BK | 1 |
| Toyoda, M | 1 |
| Sakuragawa, N | 1 |
| Arai, Y | 1 |
| Yoshikawa, H | 1 |
| Sugai, K | 1 |
| Arima, M | 1 |
| Hara, T | 1 |
| Iio, M | 1 |
| Satoyoshi, E | 1 |
| Ichiki, T | 1 |
| Tanaka, M | 1 |
| Nishikimi, M | 1 |
| Suzuki, H | 1 |
| Ozawa, T | 1 |
| Kobayashi, M | 1 |
| Wada, Y | 1 |
| Tatsumi, C | 1 |
| Takahashi, M | 1 |
| Yorifuji, S | 1 |
| Nishikawa, Y | 1 |
| Kitaguchi, M | 1 |
| Hashimoto, S | 1 |
| Tarui, S | 1 |
| Kimura, A | 1 |
| Yoshida, I | 1 |
| Ono, E | 1 |
| Matsuishi, T | 1 |
| Yoshino, M | 1 |
| Yamashita, F | 1 |
| Yamamoto, M | 1 |
| Hashimoto, T | 1 |
| Shinka, T | 1 |
| Kuhara, T | 1 |
3 reviews available for pyruvic acid and Brain Disorders
| Article | Year |
|---|---|
Extracorporeal methods of blood glutamate scavenging: a novel therapeutic modality.
Topics: Animals; Brain; Brain Diseases; Glutamic Acid; Humans; Neuroprotective Agents; Oxaloacetic Acid; Pyr | 2015 |
Monocarboxylate transporters in the brain and in cancer.
Topics: Animals; Astrocytes; Biological Transport, Active; Brain; Brain Diseases; Cognition; Gene Expression | 2016 |
Key role of acetyl-CoA in cytoplasm of nerve terminals in disturbances of acetylcholine metabolism in brain.
Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcholine; Aluminum; Animals; Brain; Brain Diseases; C | 1997 |
19 other studies available for pyruvic acid and Brain Disorders
| Article | Year |
|---|---|
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury.
Topics: Adolescent; Adult; Atrophy; Biomarkers; Brain Diseases; Brain Injuries; Chronic Disease; Cohort Stud | 2008 |
Relevance of intracranial hypertension for cerebral metabolism in aneurysmal subarachnoid hemorrhage. Clinical article.
Topics: Adult; Brain; Brain Diseases; Craniotomy; Decompression, Surgical; Energy Metabolism; Female; Glutam | 2009 |
Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain Diseases; Corpus Striatum; Endotoxins; Escherichia | 2002 |
Metabolism of pyruvate and alpha-ketoglutarate in virus-infected mouse brain.
Topics: Brain; Brain Diseases; Glutarates; Ketoglutaric Acids; Pyruvates; Pyruvic Acid; Virus Diseases | 1957 |
[On the problem of cryptogenetic processes of brain atrophy: quantitative measurements of cerebral circulation and cerebral glucose, lactic acid and pyruvic acid metabolism].
Topics: Atrophy; Brain; Brain Diseases; Cerebrovascular Circulation; Glucose; Humans; Lactates; Lactic Acid; | 1961 |
Pyruvate: an in vivo marker of cestodal infestation of the human brain on proton MR spectroscopy.
Topics: Biomarkers; Brain Diseases; Cysts; Echinococcosis; Humans; Magnetic Resonance Spectroscopy; Protons; | 2003 |
Marker of parasitic cysts on in vivo proton magnetic resonance spectroscopy: is it succinate or pyruvate?
Topics: Biomarkers; Brain Diseases; Cysts; Echinococcosis; Humans; Magnetic Resonance Spectroscopy; Pyruvic | 2004 |
Resuscitation from experimental heatstroke by hyperbaric oxygen therapy.
Topics: Animals; Biomarkers; Brain Diseases; Disease Models, Animal; Glutamic Acid; Glycerol; Heat Stroke; H | 2005 |
Studies on pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase in subacute necrotizing encephalomyelopathy.
Topics: Alanine; Brain Diseases; Carboxy-Lyases; Cells, Cultured; Dihydrolipoamide Dehydrogenase; Female; Fi | 1982 |
Mitochondrial enzyme deficiency in cerebrotendinous xanthomatosis.
Topics: Adult; Biopsy; Brain Diseases; Electron Transport; Female; Humans; Lactates; Lactic Acid; Mitochondr | 1995 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Amin | 1994 |
Capillary zone electrophoretic determination of organic acids in cerebrospinal fluid from patients with central nervous system diseases.
Topics: Brain Diseases; Cerebral Infarction; Electrophoresis; Humans; Lactates; Lactic Acid; Meningitis, Bac | 1994 |
Effect of perinatal asphyxia on systemic and intracerebral pH and glycolysis metabolism in the rat.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Chemistry; Brain Diseases; Corpus Striatum; Female; | 1997 |
The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lacticacidemia.
Topics: Acidosis, Lactic; Brain Diseases; Cells, Cultured; Cytochrome-c Oxidase Deficiency; Fibroblasts; Hum | 1990 |
Brain acidosis in experimental pneumococcal meningitis.
Topics: Acidosis; Animals; Blood Glucose; Brain Diseases; Carbon Dioxide; Glucose; Humans; Hydrogen-Ion Conc | 1989 |
Positron emission tomography using pyruvate-1-11C in two cases of mitochondrial encephalomyopathy.
Topics: Brain Diseases; Carbon Radioisotopes; Child; Female; Humans; Infant; Mitochondria; Mitochondria, Mus | 1989 |
Deficiency of subunits of Complex I and mitochondrial encephalomyopathy.
Topics: Adolescent; Biopsy; Brain Diseases; Child; Female; Humans; Immunoenzyme Techniques; Ketoglutaric Aci | 1988 |
Mitochondrial encephalomyopathy with sleep apnea.
Topics: Brain Diseases; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondria; Muscles; Muscular Di | 1988 |
Acute encephalopathy with hyperammonemia and dicarboxylic aciduria during calcium hopantenate therapy: a patient report.
Topics: Acute Disease; Ammonia; Brain Diseases; Child, Preschool; Female; gamma-Aminobutyric Acid; Humans; P | 1986 |