pyruvic acid has been researched along with Brain Damage, Chronic in 9 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When biochemical signs of cerebral ischemia progressed, i." | 1.37 | Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue. ( Nordström, CH; Reinstrup, P, 2011) |
| "Transorbital 2 hour middle cerebral artery occlusion (MCAO) was performed in eight monkeys, which were studied with continuous microdialysis for 24 hours." | 1.31 | Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model. ( Enblad, P; Frykholm, P; Hillered, L; Långström, B; Persson, L; Valtysson, J; Watanabe, Y, 2001) |
| "The majority of patients with PDHC deficiency have abnormalities in the major catalytic and regulatory subunit, E1 alpha, which is encoded on the X chromosome." | 1.29 | Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency. ( Arnold, DL; Brown, GK; Brown, RM; Legris, M; Matthews, PM; Otero, LJ; Scriver, CR; Shevell, MI, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clausen, F | 1 |
| Hillered, L | 2 |
| Gustafsson, J | 1 |
| Reinstrup, P | 1 |
| Nordström, CH | 1 |
| Schurr, A | 1 |
| Chou, YT | 1 |
| Lai, ST | 1 |
| Lee, CC | 1 |
| Lin, MT | 1 |
| Kim, TY | 1 |
| Yi, JS | 1 |
| Chung, SJ | 1 |
| Kim, DK | 1 |
| Byun, HR | 1 |
| Lee, JY | 1 |
| Koh, JY | 1 |
| Shevell, MI | 1 |
| Matthews, PM | 1 |
| Scriver, CR | 1 |
| Brown, RM | 1 |
| Otero, LJ | 1 |
| Legris, M | 1 |
| Brown, GK | 1 |
| Arnold, DL | 1 |
| Frykholm, P | 1 |
| Långström, B | 1 |
| Persson, L | 1 |
| Valtysson, J | 1 |
| Watanabe, Y | 1 |
| Enblad, P | 1 |
| Siesjö, BK | 1 |
| Ingvar, M | 1 |
| Wieloch, T | 1 |
| Yao, H | 1 |
| Sadoshima, S | 1 |
| Nishimura, Y | 1 |
| Fujii, K | 1 |
| Oshima, M | 1 |
| Ishitsuka, T | 1 |
| Fujishima, M | 1 |
2 reviews available for pyruvic acid and Brain Damage, Chronic
| Article | Year |
|---|---|
Lactate, glucose and energy metabolism in the ischemic brain (Review).
Topics: Acidosis, Lactic; Anaerobiosis; Animals; Brain; Brain Damage, Chronic; Brain Ischemia; Corticosteron | 2002 |
Cellular and molecular events underlying epileptic brain damage.
Topics: Acidosis; Animals; Brain; Brain Damage, Chronic; Calcium; Cell Survival; Cerebral Infarction; Electr | 1986 |
7 other studies available for pyruvic acid and Brain Damage, Chronic
| Article | Year |
|---|---|
Cerebral glucose metabolism after traumatic brain injury in the rat studied by 13C-glucose and microdialysis.
Topics: Anaerobiosis; Animals; Blood Glucose; Brain Damage, Chronic; Brain Injuries; Carbon Radioisotopes; E | 2011 |
Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue.
Topics: Blood Glucose; Brain Concussion; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Epoprostenol; F | 2011 |
Hypothermia attenuates circulatory shock and cerebral ischemia in experimental heatstroke.
Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Cerebrovascular Circulation; Corpus | 2003 |
Pyruvate protects against kainate-induced epileptic brain damage in rats.
Topics: Animals; Brain Damage, Chronic; Cell Death; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; H | 2007 |
Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency.
Topics: Acidosis, Lactic; Agenesis of Corpus Callosum; Brain; Brain Damage, Chronic; Brain Diseases, Metabol | 1994 |
Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model.
Topics: Animals; Brain Damage, Chronic; Extracellular Space; Glutamic Acid; Glycerol; Infarction, Middle Cer | 2001 |
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
Topics: Brain Damage, Chronic; Diabetes Mellitus; Diabetic Coma; Diabetic Neuropathies; Female; Humans; Hypo | 1989 |