pyruvic acid has been researched along with Blood Poisoning in 21 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the effect of ethyl pyruvate (EP) and alkaline phosphatase (ALP) on injuries of sepsis and the mechanism involved." | 7.75 | [Effects of ethyl pyruvate on injuries of sepsis in mice]. ( Deng, ZH; Lin, J; Ti, DD; Wang, LH; Xue, H; Yan, GT, 2009) |
| "Sepsis was induced by cecal ligation and puncture and gluconeogenesis was assessed in liver perfusion." | 5.62 | Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis. ( Bertolini, GL; Biazi, GR; de Souza Galia, WB; de Souza, HM; Frasson-Uemura, IG; Miksza, DR; Zaia, CTBV; Zaia, DAM, 2021) |
| " Ethyl pyruvate has demonstrated anti-inflammatory actions and improved hyperpermeability and bacterial translocation due to endotoxemia and is of benefit in animal models of sepsis and septic shock." | 4.83 | Is pyruvate an endogenous anti-inflammatory molecule? ( Das, UN, 2006) |
| "To explore the effect of ethyl pyruvate (EP) and alkaline phosphatase (ALP) on injuries of sepsis and the mechanism involved." | 3.75 | [Effects of ethyl pyruvate on injuries of sepsis in mice]. ( Deng, ZH; Lin, J; Ti, DD; Wang, LH; Xue, H; Yan, GT, 2009) |
| "Sepsis was induced by cecal ligation and puncture and gluconeogenesis was assessed in liver perfusion." | 1.62 | Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis. ( Bertolini, GL; Biazi, GR; de Souza Galia, WB; de Souza, HM; Frasson-Uemura, IG; Miksza, DR; Zaia, CTBV; Zaia, DAM, 2021) |
| "Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in part to unresolved inflammation." | 1.56 | Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis. ( Angus, DC; Bakalov, V; Chang, CH; Deshpande, R; Kaynar, AM; Le Moyec, L; Maloy, AL; Reyes-Uribe, L; Shapiro, SD; Wendell, SG, 2020) |
| "Mouse models of sepsis have likewise demonstrated that the absence of PPARα is associated with decreased survival and organ injury, specifically of the heart." | 1.46 | PPARα augments heart function and cardiac fatty acid oxidation in early experimental polymicrobial sepsis. ( Bennion, BG; Knowles, TO; Ledee, DR; Liles, WC; McGuire, JK; Olson, AK; Portman, MA; Standage, SW, 2017) |
| "Sepsis was induced by intravenous administration of E." | 1.37 | A positive fluid balance does not deteriorate tissue metabolism during fluid resuscitation of sepsis. ( Ferko, A; Havel, E; Hyspler, R; Koci, J; Lochman, P; Oberreiter, M; Ticha, A; Valis, M, 2011) |
| " In heart fibers a dosage of 100 microg LPS." | 1.31 | Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function. ( Gellerich, FN; Neuhof, C; Opalka, JR; Trumbeckaite, S; Zierz, S, 2001) |
| "Urea production was increased by alanine to a greater extent in the septic group compared to sham." | 1.29 | Hormone effects on hepatic substrate preference in sepsis. ( Clemens, MG; Paidas, CN, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 4 (19.05) | 2.80 |
| Authors | Studies |
|---|---|
| Shimada, BK | 1 |
| Boyman, L | 1 |
| Huang, W | 1 |
| Zhu, J | 1 |
| Yang, Y | 1 |
| Chen, F | 1 |
| Kane, MA | 1 |
| Yadava, N | 1 |
| Zou, L | 1 |
| Lederer, WJ | 1 |
| Polster, BM | 1 |
| Chao, W | 1 |
| McCall, CE | 1 |
| Zhu, X | 1 |
| Zabalawi, M | 1 |
| Long, D | 1 |
| Quinn, MA | 1 |
| Yoza, BK | 1 |
| Stacpoole, PW | 1 |
| Vachharajani, V | 1 |
| Bakalov, V | 1 |
| Reyes-Uribe, L | 1 |
| Deshpande, R | 1 |
| Maloy, AL | 1 |
| Shapiro, SD | 1 |
| Angus, DC | 1 |
| Chang, CH | 1 |
| Le Moyec, L | 1 |
| Wendell, SG | 1 |
| Kaynar, AM | 1 |
| de Souza Galia, WB | 1 |
| Biazi, GR | 1 |
| Frasson-Uemura, IG | 1 |
| Miksza, DR | 1 |
| Zaia, CTBV | 1 |
| Zaia, DAM | 1 |
| de Souza, HM | 1 |
| Bertolini, GL | 1 |
| Cui, YL | 1 |
| Wang, L | 1 |
| Tian, ZT | 1 |
| Lin, ZF | 1 |
| Chen, DC | 1 |
| Schulz, K | 1 |
| Sommer, O | 1 |
| Jargon, D | 1 |
| Utzolino, S | 1 |
| Clement, HW | 1 |
| Strate, T | 1 |
| von Dobschuetz, E | 1 |
| Standage, SW | 1 |
| Bennion, BG | 1 |
| Knowles, TO | 1 |
| Ledee, DR | 1 |
| Portman, MA | 1 |
| McGuire, JK | 1 |
| Liles, WC | 1 |
| Olson, AK | 1 |
| Deng, ZH | 1 |
| Ti, DD | 1 |
| Xue, H | 1 |
| Lin, J | 1 |
| Wang, LH | 1 |
| Yan, GT | 1 |
| Schär, J | 1 |
| Stoll, R | 1 |
| Schauer, K | 1 |
| Loeffler, DI | 1 |
| Eylert, E | 1 |
| Joseph, B | 1 |
| Eisenreich, W | 1 |
| Fuchs, TM | 1 |
| Goebel, W | 1 |
| Koci, J | 1 |
| Oberreiter, M | 1 |
| Hyspler, R | 1 |
| Ticha, A | 1 |
| Valis, M | 1 |
| Lochman, P | 1 |
| Havel, E | 1 |
| Ferko, A | 1 |
| Kopterides, P | 1 |
| Theodorakopoulou, M | 1 |
| Nikitas, N | 1 |
| Ilias, I | 1 |
| Vassiliadi, DA | 1 |
| Orfanos, SE | 1 |
| Tsangaris, I | 1 |
| Maniatis, NA | 1 |
| Tsantes, AE | 1 |
| Travlou, A | 1 |
| Dimitriadis, G | 1 |
| Armaganidis, A | 1 |
| Ungerstedt, U | 1 |
| Dimopoulou, I | 1 |
| Gutierrez, G | 1 |
| Wulf, ME | 1 |
| Das, UN | 2 |
| Wallington, J | 1 |
| Ning, J | 1 |
| Titheradge, MA | 1 |
| Tavakoli, H | 1 |
| Mela, L | 1 |
| Paidas, CN | 1 |
| Clemens, MG | 1 |
| Hotchkiss, RS | 1 |
| Rust, RS | 1 |
| Song, SK | 1 |
| Ackerman, JJ | 1 |
| Nethery, D | 1 |
| Callahan, LA | 1 |
| Stofan, D | 1 |
| Mattera, R | 1 |
| DiMarco, A | 1 |
| Supinski, G | 1 |
| Trumbeckaite, S | 1 |
| Opalka, JR | 1 |
| Neuhof, C | 1 |
| Zierz, S | 1 |
| Gellerich, FN | 1 |
| Ardawi, MS | 1 |
| Majzoub, MF | 1 |
| Kateilah, SM | 1 |
| Newsholme, EA | 1 |
3 reviews available for pyruvic acid and Blood Poisoning
| Article | Year |
|---|---|
Sepsis, pyruvate, and mitochondria energy supply chain shortage.
Topics: Acetates; Animals; Humans; Mice; Mitochondria; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Py | 2022 |
Pyruvate is an endogenous anti-inflammatory and anti-oxidant molecule.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cytokines; Free Radicals; Glucose; H | 2006 |
Is pyruvate an endogenous anti-inflammatory molecule?
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Critical Illness; Cytokines; Disease | 2006 |
18 other studies available for pyruvic acid and Blood Poisoning
| Article | Year |
|---|---|
Pyruvate-Driven Oxidative Phosphorylation is Downregulated in Sepsis-Induced Cardiomyopathy: A Study of Mitochondrial Proteome.
Topics: Animals; Cardiomyopathies; Male; Mice; Mitochondria; Mitochondrial Proteins; Myocardium; Oxidative P | 2022 |
Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.
Topics: Acetyl Coenzyme A; Animals; Citric Acid Cycle; Dichloroacetic Acid; Drosophila melanogaster; Glycoly | 2020 |
Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis.
Topics: Alanine; Animals; Gluconeogenesis; Glycerol; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats | 2021 |
Effect of rhubarb pre-treatment on intestinal microcirculation in septic rats.
Topics: Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dobutamine; Endothelial Cells; | 2014 |
Cytokine and radical inhibition in septic intestinal barrier failure.
Topics: Animals; Cyclic N-Oxides; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Free Radical Sc | 2015 |
PPARα augments heart function and cardiac fatty acid oxidation in early experimental polymicrobial sepsis.
Topics: Animals; Blotting, Western; Carbon Isotopes; Cecum; Citric Acid Cycle; Echocardiography; Fatty Acids | 2017 |
[Effects of ethyl pyruvate on injuries of sepsis in mice].
Topics: Alkaline Phosphatase; Animals; Disease Models, Animal; Intestines; Lactic Acid; Lung; Male; Mice; Py | 2009 |
Pyruvate carboxylase plays a crucial role in carbon metabolism of extra- and intracellularly replicating Listeria monocytogenes.
Topics: Animals; Aspartic Acid; Bacterial Proteins; Carbon; Carbon Isotopes; Cell Line; Culture Media; Epith | 2010 |
A positive fluid balance does not deteriorate tissue metabolism during fluid resuscitation of sepsis.
Topics: Animals; Blood Glucose; Crystalloid Solutions; Escherichia coli Infections; Fluid Therapy; Glycerol; | 2011 |
Red blood cell transfusion affects microdialysis-assessed interstitial lactate/pyruvate ratio in critically ill patients with late sepsis.
Topics: Adipose Tissue; Aged; Blood Specimen Collection; Erythrocyte Transfusion; Extracellular Fluid; Femal | 2012 |
Lactic acidosis in sepsis: another commentary.
Topics: Acidosis, Lactic; Glucose; Humans; Lactic Acid; Pyruvic Acid; Sepsis | 2005 |
The control of hepatic glycogen metabolism in an in vitro model of sepsis.
Topics: Adenylate Kinase; Animals; Cytokines; Disease Models, Animal; Glucose; Glucose-6-Phosphate; Glycogen | 2008 |
Alterations of mitochondrial metabolism and protein concentrations in subacute septicemia.
Topics: Adenosine Triphosphate; Animals; Cytochromes; Glutamates; Glutamic Acid; Ketoglutaric Acids; Kinetic | 1982 |
Hormone effects on hepatic substrate preference in sepsis.
Topics: Alanine; Animals; Energy Metabolism; Gluconeogenesis; Hormones; Lactates; Lactic Acid; Liver; Male; | 1994 |
Effect of sepsis on brain energy metabolism in normoxic and hypoxic rats.
Topics: Animals; Brain; Energy Metabolism; Female; Hypoxia; Lactates; Lactic Acid; Magnetic Resonance Spectr | 1993 |
PLA(2) dependence of diaphragm mitochondrial formation of reactive oxygen species.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cyanides; Diaphra | 2000 |
Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function.
Topics: Animals; Carnitine; Cell Respiration; Electron Transport; Female; Heart; In Vitro Techniques; Lipopo | 2001 |
Maximal activity of phosphate-dependent glutaminase and glutamine metabolism in septic rats.
Topics: Alanine; Animals; Arteries; Glutaminase; Glutamine; Intestinal Mucosa; Kidney; Lactates; Lactic Acid | 1991 |