Page last updated: 2024-10-20

pyruvic acid and Atrophy

pyruvic acid has been researched along with Atrophy in 13 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy of microneedling with 15% trichloroacetic acid (TCA) peel versus microneedling with 25% pyruvic acid peel in the management of postacne scars."9.69Microneedling in Combination With 15% Trichloroacetic Acid Peel Versus 25% Pyruvic Acid Peel in the Treatment of Acne Scars. ( Choudhary, P; Relhan, V; Sahoo, B; Sarkar, R; Solanki, B, 2023)
"The effects of treatment with indole-pyruvic acid, an endogenous metabolite of tryptophan converted into kynurenic acid in the brain, were studied in rats after transient forebrain ischemia induced by the 4-vessel occlusion procedure."7.68Indole-pyruvic acid treatment reduces damage in striatum but not in hippocampus after transient forebrain ischemia in the rat. ( Agnati, LF; Biagini, G; Ferraguti, F; Fuxe, K; Merlo Pich, E; Zoli, M, 1993)
"To compare the efficacy of microneedling with 15% trichloroacetic acid (TCA) peel versus microneedling with 25% pyruvic acid peel in the management of postacne scars."5.69Microneedling in Combination With 15% Trichloroacetic Acid Peel Versus 25% Pyruvic Acid Peel in the Treatment of Acne Scars. ( Choudhary, P; Relhan, V; Sahoo, B; Sarkar, R; Solanki, B, 2023)
"Clinical features of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) resemble those of cerebral infarcts, but the pathogenesis of infarct-like lesions is not fully understood."3.70Serial diffusion-weighted imaging in MELAS. ( Imon, Y; Kajima, T; Katayama, S; Mimori, Y; Nakamura, S; Ohshita, T; Oka, M; Watanabe, C; Yamaguchi, S, 2000)
"The effects of treatment with indole-pyruvic acid, an endogenous metabolite of tryptophan converted into kynurenic acid in the brain, were studied in rats after transient forebrain ischemia induced by the 4-vessel occlusion procedure."3.68Indole-pyruvic acid treatment reduces damage in striatum but not in hippocampus after transient forebrain ischemia in the rat. ( Agnati, LF; Biagini, G; Ferraguti, F; Fuxe, K; Merlo Pich, E; Zoli, M, 1993)
"Alpers syndrome is a progressive encephalopathy of early onset, characterized by rapid and severe developmental delay, intractable seizures and liver involvement in a previously healthy child."1.31Respiratory chain deficiency in Alpers syndrome. ( Chrétien, D; Cormier-Daire, V; de Lonlay, P; Gauthier-Villars, M; Jacquemin, E; Landrieu, P; Munnich, A; Rötig, A; Rustin, P, 2001)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's2 (15.38)18.2507
2000's4 (30.77)29.6817
2010's1 (7.69)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Hiraki, N1
Tanaka, TD1
Yoshimura, M1
Solanki, B1
Relhan, V1
Sahoo, B1
Sarkar, R1
Choudhary, P1
Sharma, U1
Upadhyay, D1
Mewar, S1
Mishra, A1
Das, P1
Gupta, SD1
Dwivedi, SN1
Makharia, GK1
Jagannathan, NR1
Marcoux, J1
McArthur, DA1
Miller, C1
Glenn, TC1
Villablanca, P1
Martin, NA1
Hovda, DA1
Alger, JR1
Vespa, PM1
HEYCK, H1
Prick, MJ1
Gabreëls, FJ2
Trijbels, JM1
Janssen, AJ1
le Coultre, R1
van Dam, K1
Jaspar, HH1
Ebels, EJ1
Op de Coul, AA1
Odessey, R1
Parr, B1
Zoli, M1
Merlo Pich, E1
Ferraguti, F1
Biagini, G1
Fuxe, K1
Agnati, LF1
Bakker, HD1
Van den Bogert, C1
Drewes, JG1
Barth, PG1
Scholte, HR1
Wanders, RJ1
Ruitenbeek, W2
Ohshita, T1
Oka, M1
Imon, Y1
Watanabe, C1
Katayama, S1
Yamaguchi, S1
Kajima, T1
Mimori, Y1
Nakamura, S1
Giordano, G1
Corradi, D1
D'Adda, T1
Melissari, M1
Gauthier-Villars, M1
Landrieu, P1
Cormier-Daire, V1
Jacquemin, E1
Chrétien, D1
Rötig, A1
Rustin, P1
Munnich, A1
de Lonlay, P1
van Erven, PM1
Renier, WO1
Thijssen, HO1
Horstink, MW1

Trials

1 trial available for pyruvic acid and Atrophy

ArticleYear
Microneedling in Combination With 15% Trichloroacetic Acid Peel Versus 25% Pyruvic Acid Peel in the Treatment of Acne Scars.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2023, 02-01, Volume: 49, Issue:2

    Topics: Acne Vulgaris; Atrophy; Cicatrix; Humans; Patient Satisfaction; Pyruvic Acid; Treatment Outcome; Tri

2023

Other Studies

12 other studies available for pyruvic acid and Atrophy

ArticleYear
A Man With Left Ventricular Hypertrophy.
    JAMA cardiology, 2022, 02-01, Volume: 7, Issue:2

    Topics: Adult; Atrophy; Cardiomyopathies; Cerebellar Diseases; Cognitive Dysfunction; Echocardiography; Gluc

2022
Metabolic abnormalities of gastrointestinal mucosa in celiac disease: An in vitro proton nuclear magnetic resonance spectroscopy study.
    Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Amino Acids; Aspartic Acid; Atrophy; Biomarkers; Celiac Disease; Citric Acid Cycl

2015
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury.
    Critical care medicine, 2008, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Atrophy; Biomarkers; Brain Diseases; Brain Injuries; Chronic Disease; Cohort Stud

2008
[On the problem of cryptogenetic processes of brain atrophy: quantitative measurements of cerebral circulation and cerebral glucose, lactic acid and pyruvic acid metabolism].
    Psychiatria et neurologia, 1961, Volume: 142

    Topics: Atrophy; Brain; Brain Diseases; Cerebrovascular Circulation; Glucose; Humans; Lactates; Lactic Acid;

1961
Progressive poliodystrophy (Alpers' disease) with a defect in cytochrome aa3 in muscle: a report of two unrelated patients.
    Clinical neurology and neurosurgery, 1983, Volume: 85, Issue:1

    Topics: Atrophy; Brain; Child; Child, Preschool; Cytochrome a Group; Cytochrome-c Oxidase Deficiency; Cytoch

1983
Effect of insulin and leucine on protein turnover in rat soleus muscle after burn injury.
    Metabolism: clinical and experimental, 1982, Volume: 31, Issue:1

    Topics: Adenosine Triphosphate; Animals; Atrophy; Burns; Insulin; Lactates; Lactic Acid; Leucine; Male; Musc

1982
Indole-pyruvic acid treatment reduces damage in striatum but not in hippocampus after transient forebrain ischemia in the rat.
    Neurochemistry international, 1993, Volume: 23, Issue:2

    Topics: Animals; Atrophy; Brain Ischemia; Cell Survival; Corpus Striatum; Dopamine and cAMP-Regulated Phosph

1993
Progressive generalized brain atrophy and infantile spasms associated with cytochrome c oxidase deficiency.
    Journal of inherited metabolic disease, 1996, Volume: 19, Issue:2

    Topics: Acidosis; Atrophy; Brain; Cytochrome-c Oxidase Deficiency; Humans; Infant, Newborn; Lactates; Lactic

1996
Serial diffusion-weighted imaging in MELAS.
    Neuroradiology, 2000, Volume: 42, Issue:9

    Topics: Adult; Atrophy; Brain; DNA, Mitochondrial; Echo-Planar Imaging; Female; Humans; Lactic Acid; Magneti

2000
[An autopsy case of neonatal lactic acidosis].
    Pathologica, 2001, Volume: 93, Issue:1

    Topics: Acidosis, Lactic; Atrophy; Autopsy; Body Fluids; Brain; Cardiomegaly; Epilepsy, Generalized; Fatal O

2001
Respiratory chain deficiency in Alpers syndrome.
    Neuropediatrics, 2001, Volume: 32, Issue:3

    Topics: Atrophy; Biopsy, Needle; Cerebral Cortex; Child, Preschool; Consanguinity; Diagnosis, Differential;

2001
Hypokinesia and rigidity as clinical manifestations of mitochondrial encephalomyopathy: report of three cases.
    Developmental medicine and child neurology, 1989, Volume: 31, Issue:1

    Topics: Adolescent; Atrophy; Brain; Brain Diseases, Metabolic; Child; Child Development; Follow-Up Studies;

1989