pyruvic acid has been researched along with Anoxemia in 120 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 7.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "We tested whether hypoxia-induced coronary artery dilatation could be mediated by an increase in adenosine concentration within the coronary artery wall or by an increase in adenosine sensitivity." | 7.73 | Adenosine concentration in the porcine coronary artery wall and A2A receptor involvement in hypoxia-induced vasodilatation. ( Deussen, A; Frøbert, O; Gravholt, CH; Haink, G; Levin, M; Simonsen, U, 2006) |
| " Neuronal glutamate stores are depleted rapidly in hypoxia, but alanine production rises under such conditions and has been suggested to be a potential precursor of glutamate." | 7.70 | Excitatory amino acid synthesis in hypoxic brain slices: does alanine act as a substrate for glutamate production in hypoxia? ( Dixon, RM; Griffin, JL; Matthews, PM; Radda, GK; Rae, C, 1998) |
| "The effect of hypoxia on the elimination of omeprazole, a potent inhibitor of gastric acid secretion, was studied in the isolated perfused rat liver." | 7.67 | Effect of hypoxia on oxidative and reductive pathways of omeprazole metabolism by the isolated perfused rat liver. ( Jones, DB; Mihaly, GW; Morgan, DJ; Smallwood, RA; Webster, LK, 1985) |
| "This study demonstrates that acute high altitude hypoxia upregulated the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation, but downregulated glycolysis in the liver of mice." | 5.91 | Energy metabolic mechanisms for high altitude sickness: Downregulation of glycolysis and upregulation of the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation. ( Jiang, C; Li, Y; Liao, N; Liu, G; Shang, X; Shao, D; Shi, J; Xu, F; Yin, D, 2023) |
| "Intraluminal microdialysis revealed signs of intestinal hypoxia and cellular damage, with a marked increase of lactate and glycerol." | 3.78 | Intraluminal intestinal microdialysis detects markers of hypoxia and cell damage in experimental necrotizing enterocolitis. ( Carlsson, PO; Hillered, L; Högberg, N; Lilja, HE; Stenbäck, A, 2012) |
| " Diameter responses and interstitial lactate/pyruvate ratios were studied during 90 min hypoxia, hypoxia + reoxygenation (60 min), nitroglycerin (100 microm, 90 min), and nitroglycerin + wash-out (60 min)." | 3.73 | HSP20 phosphorylation and interstitial metabolites in hypoxia-induced dilation of swine coronary arteries. ( Buus, CL; Frøbert, O; Rembold, CM, 2005) |
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 3.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "We tested whether hypoxia-induced coronary artery dilatation could be mediated by an increase in adenosine concentration within the coronary artery wall or by an increase in adenosine sensitivity." | 3.73 | Adenosine concentration in the porcine coronary artery wall and A2A receptor involvement in hypoxia-induced vasodilatation. ( Deussen, A; Frøbert, O; Gravholt, CH; Haink, G; Levin, M; Simonsen, U, 2006) |
| " Hypoxia induced an immediate and significant elevation in the intraperitoneal lactate/pyruvate ratio to 446+/-137% of the baseline values, and glycerol subsequently increased during reoxygenation to 389+/-109%." | 3.71 | Intraperitoneal microdialysis for detection of splanchnic metabolic disorders. ( Bahlmann, L; Bruch, HP; Gliemroth, J; Heringlake, M; Klaus, S, 2002) |
| " Neuronal glutamate stores are depleted rapidly in hypoxia, but alanine production rises under such conditions and has been suggested to be a potential precursor of glutamate." | 3.70 | Excitatory amino acid synthesis in hypoxic brain slices: does alanine act as a substrate for glutamate production in hypoxia? ( Dixon, RM; Griffin, JL; Matthews, PM; Radda, GK; Rae, C, 1998) |
| " Hyperlactatemia with L/P ratio elevation and lactic acidosis is likely to be associated with inadequate tissue perfusion." | 3.70 | Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions. ( Kari, A; Ruokonen, E; Suistomaa, M; Takala, J, 2000) |
| " We measured active stress, myosin phosphorylation, O2 consumption, and tissue ATP content in bovine tracheal smooth muscle activated by K+ depolarization when glucose was replaced by pyruvate and when oxidative metabolism was inhibited by hypoxia or uncoupled by 2,4-dinitrophenol." | 3.68 | Effects of substrate and inhibition of oxidative metabolism on contraction and myosin phosphorylation in ASM. ( Hai, CM; Kim, E; Reyes, V; Wallach, SJ; Watson, C; Xu, J, 1993) |
| "Previous studies in this laboratory showed that hypoxia and anoxia enhance the susceptibility of hepatocytes to tert-butylhydroperoxide (TBH)-induced oxidative injury." | 3.68 | Postanoxic oxidative injury in rat hepatocytes: lactate-dependent protection against tert-butylhydroperoxide. ( Aw, TY; Jones, DP; Kowalski, DP; Park, Y, 1992) |
| "The effect of hypoxia on the elimination of omeprazole, a potent inhibitor of gastric acid secretion, was studied in the isolated perfused rat liver." | 3.67 | Effect of hypoxia on oxidative and reductive pathways of omeprazole metabolism by the isolated perfused rat liver. ( Jones, DB; Mihaly, GW; Morgan, DJ; Smallwood, RA; Webster, LK, 1985) |
| "Early-onset hyperlactatemia is that which develops in the operating room or very early following intensive care unit (ICU) admission." | 2.55 | Hyperlactatemia and Cardiac Surgery. ( Minton, J; Sidebotham, DA, 2017) |
| "This study demonstrates that acute high altitude hypoxia upregulated the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation, but downregulated glycolysis in the liver of mice." | 1.91 | Energy metabolic mechanisms for high altitude sickness: Downregulation of glycolysis and upregulation of the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation. ( Jiang, C; Li, Y; Liao, N; Liu, G; Shang, X; Shao, D; Shi, J; Xu, F; Yin, D, 2023) |
| "Gestational hypoxemia is often associated with reduced birth weight, yet how hypoxemia controls uteroplacental nutrient metabolism and supply to the fetus is unclear." | 1.62 | Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia. ( Brown, LD; Jones, AK; Julian, CG; Limesand, SW; Lorca, RA; Moore, LG; Rozance, PJ; Wesolowski, SR, 2021) |
| "Only 65% of patients with septic shock had hyperlactataemia at the onset of shock and 76% of these also had a high lactate/pyruvate ratio." | 1.38 | Lactate/pyruvate ratio as a marker of tissue hypoxia in circulatory and septic shock. ( Bruzzi de Carvahlo, F; Cotton, F; De Backer, D; Orellano-Jimenez, C; Rimachi, R; Vincent, JL, 2012) |
| "Hypoxia and seizures early in life can cause multiple neurological deficits and even chronic epilepsy." | 1.37 | Perinatal hypoxia induces a long-lasting increase in unstimulated gaba release in rat brain cortex and hippocampus. The protective effect of pyruvate. ( Himmelreich, N; Parkhomenko, N; Pozdnyakova, N; Yatsenko, L, 2011) |
| "During hypoxemia, both the pretreatment with endotoxin and nicotine induced higher levels of extracellular lactate and peak lactate/pyruvate ratio compared with controls (54." | 1.31 | Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia. ( Amerio, G; Frøen, JF; Saugstad, OD; Stray-Pedersen, B, 2002) |
| "Progressive graded hypoxemia was induced by decreasing fractional inspiratory oxygen concentration (FIO2) from 1." | 1.30 | Mixed venous oxygen saturation and biochemical parameters of hypoxia during progressive hypoxemia in 10- to 14-day-old piglets. ( Blanco, CE; Maertzdorf, WJ; van der Hoeven, MA, 1997) |
| "Glycogen depletion by anoxia or glucagon before ischemia impaired recovery." | 1.29 | Metabolic recovery of isolated working rat heart after brief global ischemia. ( Goodwin, GW; Taegtmeyer, H, 1994) |
| "During lung anoxia produced by ventilation with CO, glucose utilization and lactate production were again markedly decreased by addition of lactate (2 mM) to the perfusate." | 1.27 | Lactate and regulation of lung glycolytic rate. ( Dodia, C; Fisher, AB, 1984) |
| "At the end of anoxia, hyperglycemic cats exhibited significantly higher cortical lactate and glucose levels but similarly reduced high-energy phosphate concentrations compared to normoglycemic cats." | 1.27 | Hyperglycemia preserves brain mitochondrial respiration during anoxia. ( Myers, RE; Wagner, KR, 1986) |
| "After 15 min of hypoxemia we repeated the measurements." | 1.26 | Fetal myocardial oxygen and carbohydrate consumption during acutely induced hypoxemia. ( Fisher, DJ; Heymann, MA; Rudolph, AM, 1982) |
| "We conclude that with progressive hypoxemia, CMRO2 remains stable until oxygen demand exceeds oxygen delivery, resulting thereafter in a progressive reduction in CMRO2." | 1.26 | Canine cerebral metabolism and blood flow during hypoxemia and normoxic recovery from hypoxemia. ( Artru, AA; Michenfelder, JD, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (28.33) | 18.7374 |
| 1990's | 19 (15.83) | 18.2507 |
| 2000's | 29 (24.17) | 29.6817 |
| 2010's | 31 (25.83) | 24.3611 |
| 2020's | 7 (5.83) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, AK | 1 |
| Rozance, PJ | 1 |
| Brown, LD | 1 |
| Lorca, RA | 1 |
| Julian, CG | 1 |
| Moore, LG | 1 |
| Limesand, SW | 1 |
| Wesolowski, SR | 1 |
| Wik, JA | 1 |
| Chowdhury, A | 1 |
| Kolan, S | 1 |
| Bastani, NE | 1 |
| Li, G | 1 |
| Alam, K | 1 |
| Grimolizzi, F | 1 |
| Skålhegg, BS | 1 |
| Mao, L | 1 |
| Yuan, X | 1 |
| Su, J | 1 |
| Ma, Y | 1 |
| Li, C | 1 |
| Chen, H | 1 |
| Zhang, F | 1 |
| Liu, G | 1 |
| Li, Y | 1 |
| Liao, N | 1 |
| Shang, X | 1 |
| Xu, F | 1 |
| Yin, D | 1 |
| Shao, D | 1 |
| Jiang, C | 1 |
| Shi, J | 1 |
| Ren, L | 1 |
| Zhang, H | 2 |
| Zhou, J | 1 |
| Wu, Y | 1 |
| Liu, B | 1 |
| Wang, S | 1 |
| Liu, X | 1 |
| Hao, X | 1 |
| Zhao, L | 2 |
| Gándara, L | 1 |
| Durrieu, L | 1 |
| Behrensen, C | 1 |
| Wappner, P | 1 |
| Mikrogeorgiou, A | 1 |
| Chen, Y | 1 |
| Lee, BS | 1 |
| Bok, R | 1 |
| Sheldon, RA | 1 |
| Barkovich, AJ | 1 |
| Xu, D | 1 |
| Ferriero, DM | 1 |
| Levitt, DG | 1 |
| Levitt, JE | 1 |
| Levitt, MD | 1 |
| Zabielska, MA | 1 |
| Adamus, J | 1 |
| Kowalski, R | 1 |
| Gebicki, J | 1 |
| Slominska, EM | 1 |
| Khalpey, Z | 1 |
| Smolenski, RT | 1 |
| Wang, Y | 1 |
| Huang, Y | 1 |
| Yang, J | 1 |
| Zhou, FQ | 2 |
| Zhou, H | 1 |
| Li, TX | 1 |
| Liu, RH | 1 |
| Wang, XB | 1 |
| Luo, J | 1 |
| Luo, JG | 1 |
| Kong, LY | 1 |
| Yang, MH | 1 |
| Parveen, M | 1 |
| Miyagi, A | 1 |
| Kawai-Yamada, M | 1 |
| Rashid, MH | 1 |
| Asaeda, T | 1 |
| Morash, AJ | 1 |
| Kotwica, AO | 1 |
| Murray, AJ | 2 |
| Ryou, MG | 1 |
| Choudhury, GR | 1 |
| Winters, A | 1 |
| Xie, L | 1 |
| Mallet, RT | 1 |
| Yang, SH | 1 |
| Laustsen, C | 1 |
| Lycke, S | 1 |
| Palm, F | 1 |
| Østergaard, JA | 1 |
| Bibby, BM | 1 |
| Nørregaard, R | 1 |
| Flyvbjerg, A | 1 |
| Pedersen, M | 1 |
| Ardenkjaer-Larsen, JH | 1 |
| Wang, YP | 1 |
| Wei, JY | 1 |
| Yang, JJ | 1 |
| Gao, WN | 1 |
| Wu, JQ | 1 |
| Guo, CJ | 1 |
| Zoremba, N | 1 |
| Homola, A | 1 |
| Rossaint, R | 1 |
| Syková, E | 1 |
| Bluff, JE | 1 |
| Reynolds, S | 1 |
| Metcalf, S | 1 |
| Alizadeh, T | 1 |
| Kazan, SM | 1 |
| Bucur, A | 1 |
| Wholey, EG | 1 |
| Bibby, BA | 1 |
| Williams, L | 1 |
| Paley, MN | 1 |
| Tozer, GM | 1 |
| Horscroft, JA | 1 |
| Burgess, SL | 1 |
| Hu, Y | 1 |
| Giampazolias, E | 1 |
| Tait, SW | 1 |
| Plecitá-Hlavatá, L | 1 |
| Tauber, J | 1 |
| Li, M | 1 |
| Flockton, AR | 1 |
| Pullamsetti, SS | 1 |
| Chelladurai, P | 1 |
| D'Alessandro, A | 1 |
| El Kasmi, KC | 1 |
| Ježek, P | 1 |
| Stenmark, KR | 1 |
| Nam, H | 1 |
| Jones, D | 1 |
| Cooksey, RC | 1 |
| Gao, Y | 1 |
| Sink, S | 1 |
| Cox, J | 1 |
| McClain, DA | 1 |
| Scheer, M | 1 |
| Bischoff, AM | 1 |
| Kruzliak, P | 1 |
| Opatrilova, R | 1 |
| Bovell, D | 1 |
| Büsselberg, D | 1 |
| Leung, LY | 1 |
| Deng-Bryant, Y | 1 |
| Cardiff, K | 1 |
| Winter, M | 1 |
| Tortella, F | 1 |
| Shear, D | 1 |
| Olivares-González, L | 1 |
| Martínez-Fernández de la Cámara, C | 1 |
| Hervás, D | 1 |
| Marín, MP | 1 |
| Lahoz, A | 1 |
| Millán, JM | 1 |
| Rodrigo, R | 1 |
| Minton, J | 1 |
| Sidebotham, DA | 1 |
| Gao, Q | 1 |
| Wolin, MS | 2 |
| Richards, JG | 2 |
| Sardella, BA | 1 |
| Schulte, PM | 2 |
| Hyder, A | 1 |
| Laue, C | 1 |
| Schrezenmeir, J | 1 |
| Rocha, M | 1 |
| Licausi, F | 1 |
| Araújo, WL | 1 |
| Nunes-Nesi, A | 1 |
| Sodek, L | 1 |
| Fernie, AR | 1 |
| van Dongen, JT | 1 |
| Pietsch, UC | 1 |
| Herrmann, ML | 1 |
| Uhlmann, D | 1 |
| Busch, T | 1 |
| Hokema, F | 1 |
| Kaisers, UX | 1 |
| Schaffranietz, L | 1 |
| Pozdnyakova, N | 1 |
| Yatsenko, L | 1 |
| Parkhomenko, N | 1 |
| Himmelreich, N | 1 |
| Jung, SY | 1 |
| Song, HS | 1 |
| Park, SY | 1 |
| Chung, SH | 1 |
| Kim, YJ | 1 |
| Kennedy, A | 1 |
| Frank, RN | 1 |
| Goda, N | 1 |
| Kanai, M | 1 |
| Heather, LC | 1 |
| Cole, MA | 1 |
| Tan, JJ | 1 |
| Ambrose, LJ | 1 |
| Pope, S | 1 |
| Abd-Jamil, AH | 1 |
| Carter, EE | 1 |
| Dodd, MS | 1 |
| Yeoh, KK | 1 |
| Schofield, CJ | 1 |
| Clarke, K | 1 |
| Rimachi, R | 1 |
| Bruzzi de Carvahlo, F | 1 |
| Orellano-Jimenez, C | 1 |
| Cotton, F | 1 |
| Vincent, JL | 1 |
| De Backer, D | 1 |
| Kopterides, P | 1 |
| Theodorakopoulou, M | 1 |
| Nikitas, N | 1 |
| Ilias, I | 1 |
| Vassiliadi, DA | 1 |
| Orfanos, SE | 1 |
| Tsangaris, I | 1 |
| Maniatis, NA | 1 |
| Tsantes, AE | 1 |
| Travlou, A | 1 |
| Dimitriadis, G | 1 |
| Armaganidis, A | 1 |
| Ungerstedt, U | 3 |
| Dimopoulou, I | 1 |
| Blanié, A | 1 |
| Vigué, B | 1 |
| Benhamou, D | 1 |
| Duranteau, J | 1 |
| Geeraerts, T | 1 |
| Högberg, N | 1 |
| Carlsson, PO | 1 |
| Hillered, L | 1 |
| Stenbäck, A | 1 |
| Lilja, HE | 1 |
| Frøen, JF | 1 |
| Amerio, G | 1 |
| Stray-Pedersen, B | 1 |
| Saugstad, OD | 1 |
| Klaus, S | 2 |
| Heringlake, M | 2 |
| Gliemroth, J | 2 |
| Bruch, HP | 1 |
| Bahlmann, L | 2 |
| Perrin, A | 1 |
| Roudier, E | 1 |
| Duborjal, H | 1 |
| Bachelet, C | 1 |
| Riva-Lavieille, C | 1 |
| Leverve, X | 1 |
| Massarelli, R | 1 |
| Pagel, H | 1 |
| Staubach, K | 1 |
| HUCKABEE, WE | 2 |
| HODR, J | 1 |
| HERZMANN, J | 1 |
| JANDA, J | 1 |
| TAKESHITA, S | 1 |
| RAEIHAE, NC | 1 |
| GREENE, NM | 1 |
| TALNER, NS | 1 |
| DAHL, NA | 1 |
| BALFOUR, WM | 1 |
| NAIMARK, A | 1 |
| JONES, NL | 2 |
| LAL, S | 1 |
| LEVISON, H | 1 |
| SWYER, PR | 1 |
| Dalgard, CL | 1 |
| Lu, H | 1 |
| Mohyeldin, A | 1 |
| Verma, A | 1 |
| Hlatky, R | 1 |
| Valadka, AB | 1 |
| Goodman, JC | 1 |
| Contant, CF | 1 |
| Robertson, CS | 1 |
| Ahmad, R | 1 |
| Hasnain, AU | 1 |
| Havenauskas, BL | 1 |
| Man'kovs'ka, IM | 1 |
| Nosar, VI | 1 |
| Nazarenko, AI | 1 |
| Bratus', LV | 1 |
| Frøbert, O | 2 |
| Buus, CL | 1 |
| Rembold, CM | 1 |
| Chang, CP | 1 |
| Chen, SH | 1 |
| Lin, MT | 1 |
| Haink, G | 1 |
| Simonsen, U | 1 |
| Gravholt, CH | 1 |
| Levin, M | 1 |
| Deussen, A | 1 |
| Gupte, SA | 1 |
| Diederen, RM | 1 |
| Starnes, CA | 1 |
| Berkowitz, BA | 1 |
| Winkler, BS | 1 |
| Zhang, Q | 1 |
| Wang, SY | 1 |
| Nottke, AC | 1 |
| Rocheleau, JV | 1 |
| Piston, DW | 1 |
| Goodman, RH | 1 |
| Wang, YS | 1 |
| Brauner, CJ | 1 |
| Gonzalez, RJ | 1 |
| Patrick, ML | 1 |
| Choppari-Gomes, AR | 1 |
| Almeida-Val, VM | 1 |
| Val, AL | 1 |
| Eldridge, F | 1 |
| Kelly, DP | 1 |
| McDonough, KH | 1 |
| Spitzer, JJ | 1 |
| Karcher, L | 1 |
| Zagermann, P | 1 |
| Krieglstein, J | 1 |
| Connett, RJ | 1 |
| Gayeski, TE | 1 |
| Honig, CR | 1 |
| Quatrini, U | 1 |
| Licciardi, A | 2 |
| Fisher, AB | 1 |
| Dodia, C | 1 |
| Lubek, BM | 1 |
| Mainwood, GW | 1 |
| Benzi, G | 2 |
| Arrigoni, E | 2 |
| Agnoli, A | 1 |
| Raimondo, S | 2 |
| Fulle, D | 2 |
| Pastoris, O | 2 |
| Curti, D | 2 |
| Villa, RF | 2 |
| Arizmendi, C | 1 |
| Maties, M | 1 |
| Benito, M | 1 |
| Medina, JM | 1 |
| Fisher, DJ | 2 |
| Heymann, MA | 2 |
| Rudolph, AM | 2 |
| Jones, DP | 2 |
| Kennedy, FG | 1 |
| Artru, AA | 1 |
| Michenfelder, JD | 1 |
| Yamamoto, C | 1 |
| Mori, S | 2 |
| Murakami, K | 2 |
| Yoshino, M | 2 |
| Pison, CM | 1 |
| Chauvin, C | 1 |
| Fontaine, E | 1 |
| Catelloni, F | 1 |
| Keriel, C | 1 |
| Paramelle, B | 1 |
| Leverve, XM | 1 |
| Goodwin, GW | 1 |
| Taegtmeyer, H | 1 |
| Rigobello, MP | 2 |
| Bindoli, A | 2 |
| Hai, CM | 1 |
| Watson, C | 1 |
| Wallach, SJ | 1 |
| Reyes, V | 1 |
| Kim, E | 1 |
| Xu, J | 1 |
| Wiener, CM | 1 |
| Sylvester, JT | 1 |
| Gutierrez-Juárez, R | 1 |
| Madrid-Marina, V | 1 |
| Piña, E | 1 |
| Hotchkiss, RS | 1 |
| Rust, RS | 1 |
| Song, SK | 1 |
| Ackerman, JJ | 1 |
| Rosen, CL | 1 |
| Schecter, WS | 1 |
| Mellins, RB | 1 |
| Haddad, GG | 1 |
| Barzon, E | 1 |
| Ori, C | 1 |
| Cavallini, L | 1 |
| Freo, U | 1 |
| Ruggero, S | 1 |
| Ermani, M | 1 |
| Pizzolato, G | 1 |
| Dam, M | 1 |
| van der Hoeven, MA | 2 |
| Maertzdorf, WJ | 2 |
| Blanco, CE | 2 |
| Thoresen, M | 1 |
| Hallström, A | 1 |
| Whitelaw, A | 1 |
| Puka-Sundvall, M | 1 |
| Løberg, EM | 1 |
| Satas, S | 1 |
| Steen, PA | 1 |
| Hagberg, H | 1 |
| Griffin, JL | 1 |
| Rae, C | 1 |
| Dixon, RM | 1 |
| Radda, GK | 1 |
| Matthews, PM | 1 |
| Mizock, BA | 1 |
| Parolin, ML | 1 |
| Spriet, LL | 1 |
| Hultman, E | 1 |
| Hollidge-Horvat, MG | 1 |
| Heigenhauser, GJ | 1 |
| Harvey, PJ | 1 |
| Gready, JE | 1 |
| Yin, Z | 1 |
| Le Couteur, DG | 1 |
| McLean, AJ | 1 |
| Suistomaa, M | 1 |
| Ruokonen, E | 1 |
| Kari, A | 1 |
| Takala, J | 1 |
| Arbour, R | 1 |
| Esparis, B | 1 |
| Grande, PO | 1 |
| Möller, AD | 1 |
| Nordström, CH | 1 |
| Kaloyianni, M | 1 |
| Papaefthimiou, I | 1 |
| Simeonidou, V | 1 |
| Knopp, A | 1 |
| Thierfelder, S | 1 |
| Doepner, B | 1 |
| Benndorf, K | 1 |
| Ganushchak, YM | 1 |
| Maessen, JG | 1 |
| de Jong, DS | 1 |
| Van Cappellen Van Walsum, AM | 1 |
| Jongsma, HW | 1 |
| Wevers, RA | 1 |
| Nijhuis, JG | 1 |
| Crevels, J | 1 |
| Engelke, UF | 1 |
| De Abreu, RA | 1 |
| Moolenaar, SH | 1 |
| Oeseburg, B | 1 |
| Nijland, R | 1 |
| Kowalski, DP | 1 |
| Aw, TY | 1 |
| Park, Y | 1 |
| Bennie, RE | 1 |
| Packer, CS | 1 |
| Powell, DR | 1 |
| Jin, N | 1 |
| Rhoades, RA | 1 |
| Gupta, RK | 1 |
| Wittenberg, BA | 1 |
| Morici, G | 1 |
| Ikeda, M | 1 |
| Busto, R | 1 |
| Yoshida, S | 1 |
| Santiso, M | 1 |
| Martinez, E | 1 |
| Ginsberg, MD | 1 |
| Wagner, KR | 1 |
| Myers, RE | 1 |
| Krivokapich, J | 1 |
| Keen, RE | 1 |
| Phelps, ME | 1 |
| Shine, KI | 1 |
| Barrio, JR | 1 |
| Katsumata, Y | 1 |
| Takabayashi, A | 1 |
| Sadeghi, AM | 1 |
| Breda, MA | 1 |
| Laks, H | 1 |
| Chang, PA | 1 |
| Laidig, CA | 1 |
| Wu, A | 1 |
| Bhuta, S | 1 |
| Drinkwater, DC | 1 |
| Angus, PW | 1 |
| Mihaly, GW | 2 |
| Morgan, DJ | 2 |
| Smallwood, RA | 2 |
| Sanchez-Prieto, J | 1 |
| Harvey, SA | 1 |
| Clark, JB | 1 |
| Webster, LK | 1 |
| Jones, DB | 1 |
| Gräfenstein, K | 1 |
| Duchna, W | 1 |
| Ishikawa, S | 1 |
| Vassalle, M | 1 |
| Sadchikov, DV | 1 |
| Kutyreva, NV | 1 |
| Lugovskaia, TB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Mean Arterial Pressure (MAP) Trial: Study Protocol for a Multicenter, Randomized, Controlled Trial to Compare Three Different Strategies of Mean Arterial Pressure Management During Cardiopulmonary By-pass[NCT05740397] | 900 participants (Anticipated) | Interventional | 2021-05-03 | Recruiting | |||
| Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock: ANDROMEDA-SHOCK PHYSIOLOGY STUDY[NCT03762005] | 46 participants (Anticipated) | Interventional | 2018-06-01 | Recruiting | |||
| Remote Ischemic Conditioning as a Treatment for Traumatic Brain Injury: a Prospective Randomized Controlled Trial.[NCT03176823] | 40 participants (Anticipated) | Interventional | 2019-05-03 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for pyruvic acid and Anoxemia
| Article | Year |
|---|---|
Quantitative Assessment of Blood Lactate in Shock: Measure of Hypoxia or Beneficial Energy Source.
Topics: Animals; Critical Illness; Disease Models, Animal; Dogs; Humans; Hypoxia; Lactic Acid; Liver; Models | 2020 |
Pyruvate is a prospective alkalizer to correct hypoxic lactic acidosis.
Topics: Acidosis, Lactic; Antacids; Bicarbonates; Erythropoietin; Fluid Therapy; Humans; Hypoxia; Hypoxia-In | 2018 |
Mitochondria and the hallmarks of cancer.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Death; Energy Metabolism; Gene Expression Regulatio | 2016 |
Hyperlactatemia and Cardiac Surgery.
Topics: Acidosis, Lactic; Biomarkers; Cardiac Surgical Procedures; Humans; Hyperlactatemia; Hypoxia; Lactic | 2017 |
Hypoxia-inducible factors and their roles in energy metabolism.
Topics: Animals; Carbohydrate Metabolism; Energy Metabolism; Humans; Hypoxia; Hypoxia-Inducible Factor 1; La | 2012 |
2 trials available for pyruvic acid and Anoxemia
| Article | Year |
|---|---|
Blood lactate and pyruvate levels in the perioperative period of liver resection with Pringle maneuver.
Topics: Bile Ducts; Blood Loss, Surgical; Constriction; Female; Hepatectomy; Hepatic Artery; Humans; Hypoxia | 2010 |
Low-dose prostacyclin in treatment of severe brain trauma evaluated with microdialysis and jugular bulb oxygen measurements.
Topics: Adult; Aged; Biomarkers; Brain Injuries; Energy Metabolism; Epoprostenol; Female; Humans; Hypoxia; J | 2000 |
113 other studies available for pyruvic acid and Anoxemia
| Article | Year |
|---|---|
Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia.
Topics: Adaptation, Physiological; Amino Acids; AMP-Activated Protein Kinase Kinases; Animals; Female; Glyco | 2021 |
Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4+ T-cell proliferation and glycolytic activity under hypoxia and normoxia.
Topics: Amino Acids; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; Cell Proliferation; Glucose; Gl | 2022 |
Human Umbilical Vein Endothelial Cells Survive on the Ischemic TCA Cycle under Lethal Ischemic Conditions.
Topics: Avidin; Citrate (si)-Synthase; Citric Acid Cycle; Coenzyme A; Human Umbilical Vein Endothelial Cells | 2022 |
Energy metabolic mechanisms for high altitude sickness: Downregulation of glycolysis and upregulation of the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation.
Topics: Altitude; Altitude Sickness; Amino Acids; Animals; Citric Acid Cycle; Down-Regulation; Fatty Acids; | 2023 |
Unique and generic crossed metabolism in response to four sub-lethal environmental stresses in the oriental fruit fly, Bactrocera dorsalis Hendel.
Topics: Animals; Drosophila; Fatty Acids; Hypoxia; Pyruvic Acid; Tephritidae | 2023 |
A genetic toolkit for the analysis of metabolic changes in Drosophila provides new insights into metabolic responses to stress and malignant transformation.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Drosophila melanogas | 2019 |
A Metabolomics Study of Hypoxia Ischemia during Mouse Brain Development Using Hyperpolarized 13C.
Topics: Animals; Brain; Carbon Isotopes; Hypoxia; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonanc | 2020 |
Cardioprotective effect of N-methylnicotinamide salt of pyruvate in experimental model of cardiac hypoxia.
Topics: Animals; Apolipoproteins E; Cardiotonic Agents; Creatine Kinase; Electrocardiography; Heart; Hypoxia | 2018 |
Hypoxia-Protective Azaphilone Adducts from Peyronellaea glomerata.
Topics: Apoptosis; Ascomycota; Benzopyrans; Cells, Cultured; Crystallography, X-Ray; Endophytes; Human Umbil | 2018 |
Metabolic and biochemical responses of Potamogeton anguillanus Koidz. (Potamogetonaceae) to low oxygen conditions.
Topics: Alcohol Dehydrogenase; Catalase; Glycolysis; Hydrogen Peroxide; Hypoxia; Indoleacetic Acids; Oxygen; | 2019 |
Tissue-specific changes in fatty acid oxidation in hypoxic heart and skeletal muscle.
Topics: Adaptation, Physiological; Animals; Fatty Acids; Hypoxia; Mice; Mice, Inbred C57BL; Muscle, Skeletal | 2013 |
Pyruvate minimizes rtPA toxicity from in vitro oxygen-glucose deprivation and reoxygenation.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Cells, Cultured; Endothelial Cells; Glucose; Hypoxia; Mice; | 2013 |
High altitude may alter oxygen availability and renal metabolism in diabetics as measured by hyperpolarized [1-(13)C]pyruvate magnetic resonance imaging.
Topics: Alanine; Altitude; Altitude Sickness; Animals; Atmospheric Pressure; Bicarbonates; Blood Glucose; Di | 2014 |
Riboflavin supplementation improves energy metabolism in mice exposed to acute hypoxia.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Carnitine; Dietary Supplements; Drug Evaluation, Prec | 2014 |
Interstitial lactate, lactate/pyruvate and glucose in rat muscle before, during and in the recovery from global hypoxia.
Topics: Animals; Energy Metabolism; Glucose; Hypoxia; Lactic Acid; Male; Microdialysis; Muscle, Skeletal; Py | 2014 |
Measurement of the acute metabolic response to hypoxia in rat tumours in vivo using magnetic resonance spectroscopy and hyperpolarised pyruvate.
Topics: Animals; Carbon Isotopes; Disease Models, Animal; Fibrosarcoma; Hypoxia; Lactic Acid; Magnetic Reson | 2015 |
Altered Oxygen Utilisation in Rat Left Ventricle and Soleus after 14 Days, but Not 2 Days, of Environmental Hypoxia.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Energy Metabolism; Gene Expression; Heart Vent | 2015 |
Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.
Topics: Animals; Cattle; Cell Respiration; Cellular Reprogramming; Chronic Disease; Citric Acid Cycle; Down- | 2016 |
Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver.
Topics: Animals; Gluconeogenesis; Glucose; Hypoglycemia; Hypoxia; Iron; Iron Deficiencies; Liver; Male; Mice | 2016 |
Creatine and creatine pyruvate reduce hypoxia-induced effects on phrenic nerve activity in the juvenile mouse respiratory system.
Topics: Aging; Animals; Creatine; Hypoxia; Mice; Motor Activity; Phrenic Nerve; Pyruvic Acid; Respiratory Sy | 2016 |
Neurochemical changes following combined hypoxemia and hemorrhagic shock in a rat model of penetrating ballistic-like brain injury: A microdialysis study.
Topics: Animals; Brain; Disease Models, Animal; Glucose; Head Injuries, Penetrating; Hypoxia; Lactic Acid; M | 2016 |
cGMP-Phosphodiesterase Inhibition Prevents Hypoxia-Induced Cell Death Activation in Porcine Retinal Explants.
Topics: Animals; Antioxidants; Caspase 3; Cell Death; Cyclic GMP; Gene Expression Regulation; Hypoxia; Hypox | 2016 |
Effects of hypoxia on relationships between cytosolic and mitochondrial NAD(P)H redox and superoxide generation in coronary arterial smooth muscle.
Topics: Animals; Cattle; Coronary Vessels; Cytosol; Fluorescent Dyes; Hypoxia; In Vitro Techniques; Lactic A | 2008 |
Regulation of pyruvate dehydrogenase in the common killifish, Fundulus heteroclitus, during hypoxia exposure.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Energy Metabolism; Fundulidae; Hypo | 2008 |
Metabolic aspects of neonatal rat islet hypoxia tolerance.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cyclic AMP; Gluc | 2010 |
Glycolysis and the tricarboxylic acid cycle are linked by alanine aminotransferase during hypoxia induced by waterlogging of Lotus japonicus.
Topics: Adenosine Triphosphate; Alanine; Alanine Transaminase; Citric Acid Cycle; Fermentation; Gene Express | 2010 |
Perinatal hypoxia induces a long-lasting increase in unstimulated gaba release in rat brain cortex and hippocampus. The protective effect of pyruvate.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Dose-Response Relationship, Drug; Extracellular Space; g | 2011 |
Pyruvate promotes tumor angiogenesis through HIF-1-dependent PAI-1 expression.
Topics: Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Electrophoretic Mobility Shift Assay; | 2011 |
The influence of glucose concentration and hypoxia on VEGF secretion by cultured retinal cells.
Topics: Animals; Cattle; Cells, Cultured; Endothelium, Vascular; Glucose; Humans; Hypoxia; Lactic Acid; Pyru | 2011 |
Metabolic adaptation to chronic hypoxia in cardiac mitochondria.
Topics: Aconitate Hydratase; Adaptation, Physiological; Animals; Cell Respiration; Chronic Disease; Disease | 2012 |
Lactate/pyruvate ratio as a marker of tissue hypoxia in circulatory and septic shock.
Topics: Aerobiosis; Aged; APACHE; Biomarkers; Female; Humans; Hypoxia; Lactic Acid; Male; Middle Aged; Pyruv | 2012 |
Red blood cell transfusion affects microdialysis-assessed interstitial lactate/pyruvate ratio in critically ill patients with late sepsis.
Topics: Adipose Tissue; Aged; Blood Specimen Collection; Erythrocyte Transfusion; Extracellular Fluid; Femal | 2012 |
The frontal lobe and thalamus have different sensitivities to hypoxia-hypotension after traumatic brain injury: a microdialysis study in rats.
Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Energy Metabolism; Frontal Lob | 2012 |
Intraluminal intestinal microdialysis detects markers of hypoxia and cell damage in experimental necrotizing enterocolitis.
Topics: Animals; Biomarkers; Colon, Sigmoid; Enterocolitis, Necrotizing; Glucose; Glycerol; Hypoxia; Ileum; | 2012 |
Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain Diseases; Corpus Striatum; Endotoxins; Escherichia | 2002 |
Intraperitoneal microdialysis for detection of splanchnic metabolic disorders.
Topics: Animals; Ascitic Fluid; Cryoprotective Agents; Disease Models, Animal; Extracellular Space; Gastroin | 2002 |
Pyruvate reverses metabolic effects produced by hypoxia in glioma and hepatoma cell cultures.
Topics: Animals; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Glioma; Glucose; Humans; Hypoxia | 2002 |
Biochemical tissue monitoring during hypoxia and reoxygenation.
Topics: Acidosis; Animals; Blood Pressure; Hypoxia; Lactic Acid; Liver; Male; Microdialysis; Muscle, Skeleta | 2003 |
Relationships of pyruvate and lactate during anaerobic metabolism. II. Exercise and formation of O-debt.
Topics: Exercise; Hypoxia; Lactates; Lactic Acid; Metabolism; Pyruvates; Pyruvic Acid | 1958 |
Relationships of pyruvate and lactate during anaerobic metabolism. III. Effect of breathing low-oxygen gases.
Topics: Gases; Hypoxia; Lactates; Lactic Acid; Metabolism; Oxygen; Pyruvates; Pyruvic Acid | 1958 |
[Modification of the glycemia level, pyruvic acid level and the level of inorganic phosphorus by application of glucose during labor with consideration to hypoxia of the fetus].
Topics: Blood Glucose; Female; Fetus; Glucose; Humans; Hypoxia; Labor, Obstetric; Phosphorus; Pregnancy; Pyr | 1959 |
[Changes of serum lactic and pyruvic acid in hypoxia and hypercapnea, especially effects of respiratory changes of blood PH upon lactic acid level].
Topics: Carbon Dioxide; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1962 |
EFFECT OF ANOXIA ON LACTATE/PYRUVATE AND ATP/ADP RATIOS IN ADULT AND FETAL GUINEA PIG LIVER.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fetus; Guinea Pigs; Hyp | 1964 |
BLOOD LACTATE, PYRUVATE AND LACTATE-PYRUVATE RATIOS IN CONGENITAL HEART DISEASE.
Topics: Blood Chemical Analysis; Child; Heart Defects, Congenital; Humans; Hypoxia; Lactates; Lactic Acid; N | 1964 |
PROLONGED ANOXIC SURVIVAL DUE TO ANOXIA PRE-EXPOSURE: BRAIN ATP, LACTATE, AND PYRUVATE.
Topics: Adenosine Triphosphate; Brain; Brain Chemistry; Carbohydrate Metabolism; Glucose; Glycolysis; Hypoxi | 1964 |
THE EFFECT OF HYPOXIA ON GAS EXCHANGE AND ARTERIAL LACTATE AND PYRUVATE CONCENTRATION DURING MODERATE EXERCISE IN MAN.
Topics: Arteries; Blood; Carbon Dioxide; Exercise; Humans; Hydrogen-Ion Concentration; Hyperventilation; Hyp | 1965 |
THE ACID-BASE STATUS IN CYANOTIC CONGENITAL HEART DISEASE.
Topics: Acid-Base Equilibrium; Acidosis; Blood Gas Analysis; Cardiac Output; Heart Defects, Congenital; Huma | 1965 |
Endogenous 2-oxoacids differentially regulate expression of oxygen sensors.
Topics: Cell Line, Tumor; Central Nervous System Neoplasms; Citric Acid Cycle; DNA-Binding Proteins; Gene Ex | 2004 |
Patterns of energy substrates during ischemia measured in the brain by microdialysis.
Topics: Adult; Brain Injuries; Brain Ischemia; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Humans; H | 2004 |
Ontogenetic changes and developmental adjustments in lactate dehydrogenase isozymes of an obligate air-breathing fish Channa punctatus during deprivation of air access.
Topics: Adaptation, Physiological; Air; Animals; Asphyxia; Fishes; Hypoxia; Isoenzymes; Kinetics; L-Lactate | 2005 |
[Effect of intermittent hypoxic training on indices of adaptation to hypoxia in rats during physical exertion].
Topics: Adaptation, Physiological; Animals; Hypoxia; Lactic Acid; Male; Mitochondria, Muscle; Muscle, Skelet | 2004 |
HSP20 phosphorylation and interstitial metabolites in hypoxia-induced dilation of swine coronary arteries.
Topics: Animals; Blood Glucose; Coronary Vessels; Dilatation, Pathologic; Heat-Shock Proteins; HSP20 Heat-Sh | 2005 |
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid; | 2005 |
Adenosine concentration in the porcine coronary artery wall and A2A receptor involvement in hypoxia-induced vasodilatation.
Topics: Acetamides; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Deaminase I | 2006 |
Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Signaling | 2006 |
Reexamining the hyperglycemic pseudohypoxia hypothesis of diabetic oculopathy.
Topics: Adenosine Triphosphate; Aldehyde Reductase; Animals; Cell Culture Techniques; Diabetes Mellitus, Exp | 2006 |
Redox sensor CtBP mediates hypoxia-induced tumor cell migration.
Topics: Alcohol Oxidoreductases; Biosensing Techniques; Cadherins; Cell Movement; DNA-Binding Proteins; Gene | 2006 |
Metabolic and ionoregulatory responses of the Amazonian cichlid, Astronotus ocellatus, to severe hypoxia.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; Blood Glucose; Cichlids; Creatine; Eryth | 2007 |
Blood lactate and pyruvate in pulmonary insufficiency.
Topics: Carbon Dioxide; Humans; Hypoxia; Lactates; Oxygen; Pulmonary Valve Insufficiency; Pyruvic Acid | 1966 |
Hypoxic reprogramming.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; Basal Metabolism; Citric Acid Cycle; Ene | 2008 |
Effects of hypoxia and reoxygenation on adult rat heart cell metabolism.
Topics: Animals; Calcium; Caprylates; Carbon Dioxide; Cell Survival; Glucose; Hypoxia; Male; Myocardium; Oxy | 1983 |
Effect of an extract of Ginkgo biloba on rat brain energy metabolism in hypoxia.
Topics: Animals; Brain; Energy Metabolism; Hypoxia; Lactates; Lactic Acid; Male; Plant Extracts; Plants, Med | 1984 |
Lactate production in a pure red muscle in absence of anoxia: mechanisms and significance.
Topics: Animals; Dogs; Glycolysis; Hypoxia; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Mitochondr | 1983 |
[Acid-base equilibrium, blood lactic acid and pyruvic acid in albino rats after muscular exertion under conditions of normal oxygen, hypoxia and hypoxia-hypercapnia].
Topics: Acid-Base Equilibrium; Animals; Hypercapnia; Hypoxia; Lactates; Lactic Acid; Male; Physical Exertion | 1984 |
Lactate and regulation of lung glycolytic rate.
Topics: Animals; Glycolysis; Hypoxia; Kinetics; Lactates; Lactic Acid; Lung; Male; Pyruvates; Pyruvic Acid; | 1984 |
Lactate and pyruvate production in isolated thiamine-deficient rat diaphragm strips.
Topics: Animals; Diaphragm; Fatigue; Glucose; Glycolysis; Hydrogen; Hypoxia; In Vitro Techniques; Lactates; | 1984 |
Influence of age upon the cerebral metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
Topics: Adenine Nucleotides; Aging; Animals; Dihydroergotoxine; Dogs; Female; Hypoxia; Lactates; Lactic Acid | 1982 |
Effect of postnatal hypoxia on the energy homeostasis of the newborn rat during the early neonatal period.
Topics: Adenine Nucleotides; Alanine; Animals; Animals, Newborn; Blood Glucose; Energy Metabolism; Glucagon; | 1983 |
Fetal myocardial oxygen and carbohydrate consumption during acutely induced hypoxemia.
Topics: Animals; Blood Pressure; Coronary Circulation; Female; Fetus; Glucose; Heart; Heart Rate; Hypoxia; L | 1982 |
Intracellular oxygen supply during hypoxia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Cytochromes; Glutathione; Hypo | 1982 |
Fetal myocardial oxygen and carbohydrate metabolism in sustained hypoxemia in utero.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Coronary Vessels; Female; Fetus; Heart; Hypoxia; La | 1982 |
Metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
Topics: Adenine Nucleotides; Animals; Cerebral Cortex; Dogs; Female; Hypoxia; Lactates; Lactic Acid; Oxygen | 1981 |
Canine cerebral metabolism and blood flow during hypoxemia and normoxic recovery from hypoxemia.
Topics: Acidosis; Adenine Nucleotides; Animals; Brain; Dogs; Electroencephalography; Glucose; Hypoxia; Lacta | 1981 |
Effect of galactosamine-induced hepatitis on the aerobic and anaerobic metabolism of the rat exposed to high-altitude hypoxia.
Topics: Aerobiosis; Altitude; Anaerobiosis; Animals; Citrate (si)-Synthase; Energy Metabolism; Fatty Acids; | 1995 |
Mechanism of gluconeogenesis inhibition in rat hepatocytes isolated after in vivo hypoxia.
Topics: Adenine Nucleotides; Animals; Cell Separation; Dihydroxyacetone; Gluconeogenesis; Hypoxia; Lactates; | 1995 |
Metabolic recovery of isolated working rat heart after brief global ischemia.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Fasting; Glucose-6-Phosphate; Glucosephospha | 1994 |
Effect of pyruvate on rat heart thiol status during ischemia and hypoxia followed by reperfusion.
Topics: Animals; Cytosol; Glutathione; Hypoxia; Mitochondria, Heart; Myocardial Contraction; Myocardial Repe | 1993 |
Effects of substrate and inhibition of oxidative metabolism on contraction and myosin phosphorylation in ASM.
Topics: 2,4-Dinitrophenol; Analysis of Variance; Animals; Cattle; Dinitrophenols; Glucose; Hypoxia; Isometri | 1993 |
Effects of insulin, glucose analogues, and pyruvate on vascular responses to anoxia in isolated ferret lungs.
Topics: Animals; Ferrets; Glucose; Glycolysis; Hyperglycemia; Hypoxia; In Vitro Techniques; Insulin; Lung; M | 1993 |
Adenosine effect on lactate and pyruvate production in the hypoxic guinea pig heart.
Topics: Adenosine; Animals; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Myocard | 1993 |
Effect of sepsis on brain energy metabolism in normoxic and hypoxic rats.
Topics: Animals; Brain; Energy Metabolism; Female; Hypoxia; Lactates; Lactic Acid; Magnetic Resonance Spectr | 1993 |
Effect of acute hypoxia on metabolism and ventilation in awake piglets.
Topics: Animals; Carbon Dioxide; Hypoxia; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Pyruvates; Pyru | 1993 |
Inhibitory effect of pyruvate on release of glutathione and swelling of rat heart mitochondria.
Topics: Animals; Arsenicals; Biological Transport; Calcium; Depression, Chemical; Glutathione; Hypoxia; In V | 1995 |
The effects of propofol on cerebral high energy metabolites, lactate, and glucose in normoxic and severely hypoxic rats.
Topics: Adenine Nucleotides; Anesthetics, Intravenous; Animals; Cerebral Cortex; Energy Metabolism; Glucose; | 1997 |
Mixed venous oxygen saturation and biochemical parameters of hypoxia during progressive hypoxemia in 10- to 14-day-old piglets.
Topics: Animals; Disease Progression; Hypoxia; Lactic Acid; Linear Models; Oxygen; Pyruvic Acid; Swine; Vein | 1997 |
Lactate and pyruvate changes in the cerebral gray and white matter during posthypoxic seizures in newborn pigs.
Topics: Animals; Animals, Newborn; Cerebellum; Electroencephalography; Hypoxia; Lactic Acid; Microdialysis; | 1998 |
Excitatory amino acid synthesis in hypoxic brain slices: does alanine act as a substrate for glutamate production in hypoxia?
Topics: Alanine; Animals; Brain; Carbon; Excitatory Amino Acids; Glutamic Acid; Glutamine; Guinea Pigs; Hypo | 1998 |
Relationship between mixed venous oxygen saturation and markers of tissue oxygenation in progressive hypoxic hypoxia and in isovolemic anemic hypoxia in 8- to 12-day-old piglets.
Topics: Anemia; Animals; Animals, Newborn; Hemoglobins; Hypoxia; Lactic Acid; Oximetry; Oxygen; Oxygen Consu | 1999 |
Redox pairs, tissue hypoxia, organ dysfunction, and mortality.
Topics: Humans; Hypoxia; Ketone Bodies; Lactic Acid; Multiple Organ Failure; Oxidation-Reduction; Predictive | 2000 |
Regulation of glycogen phosphorylase and PDH during exercise in human skeletal muscle during hypoxia.
Topics: Adenosine Triphosphate; Adult; Carnitine; Coenzyme A; Energy Metabolism; Exercise; Glycogen; Glycoly | 2000 |
Acute oxygen supplementation restores markers of hepatocyte energy status and hypoxia in cirrhotic rats.
Topics: Animals; Biomarkers; Blood Gas Analysis; Carbon Tetrachloride Poisoning; Energy Metabolism; Hypoxia; | 2000 |
Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions.
Topics: Acidosis, Lactic; APACHE; Biomarkers; Critical Care; Emergencies; Female; Finland; Glasgow Coma Scal | 2000 |
Osmolar gap metabolic acidosis in a 60-year-old man treated for hypoxemic respiratory failure.
Topics: Acidosis, Lactic; Drug Combinations; Humans; Hypnotics and Sedatives; Hypoxia; Infusions, Intravenou | 2000 |
Metabolic effects induced by epinephrine in Rana balcanica erythrocytes under normoxic and hypoxic conditions.
Topics: Adenosine Triphosphate; Adrenergic Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonis | 2000 |
Mitochondria are the main ATP source for a cytosolic pool controlling the activity of ATP-sensitive K(+) channels in mouse cardiac myocytes.
Topics: Adenosine Triphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cytosol; Egtazi | 2001 |
The oxygen debt during routine cardiac surgery: illusion or reality?
Topics: Aged; Biological Availability; Coronary Artery Bypass; Female; Humans; Hypoxia; Lactic Acid; Male; M | 2002 |
1H-NMR spectroscopy of cerebrospinal fluid of fetal sheep during hypoxia-induced acidemia and recovery.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Choline; Citric Acid; Creatinine; Energy Metabolism; Femal | 2002 |
Pyruvate improvement of cellular energetics, not simply generating ATP during anoxia.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Hypoxia; Liver Transplantation; Pyruvic Acid | 2002 |
Postanoxic oxidative injury in rat hepatocytes: lactate-dependent protection against tert-butylhydroperoxide.
Topics: Animals; Free Radicals; Hypoxia; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; NAD; O | 1992 |
Biphasic contractile response of pulmonary artery to hypoxia.
Topics: Animals; Aorta; Endothelium, Vascular; Glucose; Hypoxia; In Vitro Techniques; Male; Norepinephrine; | 1991 |
31P-NMR studies of isolated adult heart cells: effect of myoglobin inactivation.
Topics: Animals; Cell Separation; Culture Media; Hypoxia; Magnetic Resonance Spectroscopy; Myocardium; Myogl | 1991 |
[Behavior of various enzyme activities during high blood lactate and pyruvate levels in albino rats reared in a normobaric hypoxic atmosphere for 1 or 2 generations].
Topics: Acid-Base Equilibrium; Adaptation, Physiological; Animals; Atmosphere Exposure Chambers; Creatine Ki | 1990 |
Cerebral phosphoinositide, triacylglycerol and energy metabolism during severe hypoxia and recovery.
Topics: Animals; Brain; Energy Metabolism; Fatty Acids; Glycogen; Hypoxia; Lipid Metabolism; Male; Phosphati | 1988 |
Hyperglycemia preserves brain mitochondrial respiration during anoxia.
Topics: Animals; Brain; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cats; Glutamates; Glutamic Acid; | 1986 |
Effects of anoxia on kinetics of [13N] glutamate and 13NH3 metabolism in rabbit myocardium.
Topics: Ammonia; Animals; Glutamates; Glutamic Acid; Hypoxia; Kinetics; Male; Myocardium; Nitrogen Radioisot | 1987 |
Stimulation of anaerobic metabolism in rats at high altitude hypoxia--adrenergic effects dependent on dietary states.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Altitude Sickness; Anaerobiosis; Animals; | 1987 |
Effects of acute hypoxia and reoxygenation in a blood-perfused neonatal heart model.
Topics: Acute Disease; Animals; Animals, Newborn; Blood; Energy Metabolism; Heart; Hypoxia; Lactates; Lactic | 1988 |
Synergistic effects of hypoxia and fasting on harmol elimination in the isolated perfused rat liver.
Topics: Alkaloids; Animals; Fasting; Glucose; Harmine; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; | 1988 |
Effects of in vitro anoxia and low pH on acetylcholine release by rat brain synaptosomes.
Topics: Acetylcholine; Animals; Brain; Calcium; Choline; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techn | 1987 |
Effect of hypoxia on oxidative and reductive pathways of omeprazole metabolism by the isolated perfused rat liver.
Topics: Animals; Benzimidazoles; Hypoxia; Lactates; Lactic Acid; Liver; Male; Omeprazole; Oxidation-Reductio | 1985 |
[Relation between glycohemoglobin, hypoxia parameters and diabetic microangiopathy].
Topics: 2,3-Diphosphoglycerate; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Re | 1985 |
Reversal of strophanthidin negative inotropy by metabolic substrates in cardiac Purkinje fibres.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Calcium; Depression, Chemical; Dogs; Female; Gluc | 1985 |
[Gas exchange and metabolic functions of the lungs in endotoxic shock].
Topics: Acidosis, Respiratory; Animals; Dogs; Female; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic | 1985 |