Page last updated: 2024-10-20

pyruvic acid and Angiospasm, Intracranial

pyruvic acid has been researched along with Angiospasm, Intracranial in 7 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Research Excerpts

ExcerptRelevanceReference
"Bedside intracerebral microdialysis monitoring of patients with subarachnoid hemorrhage and signs of delayed ischemia revealed dramatic changes in extracellular concentrations of glucose, lactate, and glycerol that could be directly correlated to the clinical status of the patients."3.70Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration. ( Brandt, L; Nilsson, OG; Säveland, H; Ungerstedt, U, 1999)
"Thirteen subarachnoid hemorrhage patients (age, 48."2.71Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study. ( Amthauer, H; Haux, D; Küchler, I; Lüdemann, L; Plotkin, M; Sarrafzadeh, AS; Unterberg, AW, 2004)
"OBJECTIVE Delayed cerebral ischemia (DCI) following subarachnoid hemorrhage (SAH) is one of the major contributors to poor outcome."1.48Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage. ( Enblad, P; Engquist, H; Hillered, L; Howells, T; Johnson, U; Lewén, A; Nilsson, P; Ronne-Engström, E; Rostami, E, 2018)
"In a 36-year-old man, an anterior communicating artery aneurysm caused an SAH (Hunt and Hess Grade IV, Fisher Grade III)."1.32Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case report. ( Behr, R; Hoelper, BM; Hofmann, E; Soldner, F; Sporleder, R, 2003)
"Even though cerebral vasospasm after subarachnoid hemorrhage (SAH) causes cerebral ischemia or infarction, the metabolic alterations in cerebrospinal fluids (CSF) after SAH have not been studied."1.31Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs. ( Aoki, K; Badr, A; Tibbs, R; Yin, W; Zhang, J, 2002)
"Even though cerebral vasospasm after subarachnoid hemorrhage (SAH) causes cerebral ischemia or infarction, the metabolic alterations in cerebrospinal fluids (CSF) after SAH have not been studied."1.31Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs. ( Aoki, K; Badr, A; Tibbs, R; Yin, W; Zhang, J, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rostami, E1
Engquist, H1
Howells, T1
Johnson, U1
Ronne-Engström, E2
Nilsson, P1
Hillered, L2
Lewén, A1
Enblad, P2
Zetterling, M1
Samuelsson, C1
Karlsson, T1
Yin, W2
Tibbs, R2
Aoki, K2
Badr, A2
Zhang, J2
Hoelper, BM1
Hofmann, E1
Sporleder, R1
Soldner, F1
Behr, R1
Sarrafzadeh, AS1
Haux, D1
Lüdemann, L1
Amthauer, H1
Plotkin, M1
Küchler, I1
Unterberg, AW1
Nilsson, OG1
Brandt, L1
Ungerstedt, U1
Säveland, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.[NCT03314779]12 participants (Actual)Observational2017-08-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for pyruvic acid and Angiospasm, Intracranial

ArticleYear
Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study.
    Stroke, 2004, Volume: 35, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Flow Velocity; Brain; Brain Ischemia; Cerebrovascular Circulation; Ex

2004

Other Studies

6 other studies available for pyruvic acid and Angiospasm, Intracranial

ArticleYear
Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage.
    Journal of neurosurgery, 2018, Volume: 128, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Cerebr

2018
Temporal patterns of interstitial pyruvate and amino acids after subarachnoid haemorrhage are related to the level of consciousness--a clinical microdialysis study.
    Acta neurochirurgica, 2009, Volume: 151, Issue:7

    Topics: Aged; Amino Acids; Biomarkers; Brain; Brain Chemistry; Brain Ischemia; Consciousness Disorders; Down

2009
Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs.
    Acta neurochirurgica. Supplement, 2002, Volume: 81

    Topics: Analysis of Variance; Animals; Caspase Inhibitors; Cerebral Hemorrhage; Disease Models, Animal; Dogs

2002
Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case report.
    Neurosurgery, 2003, Volume: 52, Issue:4

    Topics: Adult; Angioplasty, Balloon; Blood Flow Velocity; Blood Glucose; Brain; Carotid Artery, Internal; Ca

2003
Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration.
    Neurosurgery, 1999, Volume: 45, Issue:5

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain Ischemia; Cerebral Cortex; Female; Glutamic Acid; Glyc

1999
Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs.
    Neurological research, 2001, Volume: 23, Issue:1

    Topics: Animals; Basilar Artery; Caspase Inhibitors; Caspases; Cerebrospinal Fluid; Disease Models, Animal;

2001