pyruvic acid has been researched along with Angiogenesis, Pathologic in 7 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the case of cancer, both chronic and acute hypoxic areas are found in the tumor." | 2.45 | Considering the role of pyruvate in tumor cells during hypoxia. ( Perrin, A; Roudier, E, 2009) |
| "Anti-angiogenic therapies for solid tumors frequently function in two steps: the transient normalization of structurally and functionally aberrant tumor blood vessels with increased blood perfusion, followed by the pruning of tumor blood vessels and the resultant cessation of nutrients and oxygen delivery required for tumor growth." | 1.40 | In vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization. ( Devasahayam, N; Krishna, MC; Lizak, MJ; Matsumoto, S; Matsuo, M; Merkle, H; Mitchell, JB; Morris, HD; Munasinghe, JP; Saito, K; Suburamanian, S; Takakusagi, Y; Yasukawa, K, 2014) |
| "less invasive ovarian cancer cells in detachment." | 1.38 | Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration. ( Bellance, N; Caneba, CA; Nagrath, D; Pabst, L; Yang, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsumoto, S | 1 |
| Saito, K | 1 |
| Takakusagi, Y | 1 |
| Matsuo, M | 1 |
| Munasinghe, JP | 1 |
| Morris, HD | 1 |
| Lizak, MJ | 1 |
| Merkle, H | 1 |
| Yasukawa, K | 1 |
| Devasahayam, N | 1 |
| Suburamanian, S | 1 |
| Mitchell, JB | 1 |
| Krishna, MC | 1 |
| Lau, JY | 1 |
| Chen, AP | 1 |
| Gu, YP | 1 |
| Cunningham, CH | 1 |
| Roudier, E | 1 |
| Perrin, A | 1 |
| Jung, SY | 1 |
| Song, HS | 1 |
| Park, SY | 1 |
| Chung, SH | 1 |
| Kim, YJ | 1 |
| Bohndiek, SE | 1 |
| Kettunen, MI | 1 |
| Hu, DE | 1 |
| Witney, TH | 1 |
| Kennedy, BW | 1 |
| Gallagher, FA | 1 |
| Brindle, KM | 1 |
| Chang, X | 1 |
| Wei, C | 1 |
| Caneba, CA | 1 |
| Bellance, N | 1 |
| Yang, L | 1 |
| Pabst, L | 1 |
| Nagrath, D | 1 |
2 reviews available for pyruvic acid and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Considering the role of pyruvate in tumor cells during hypoxia.
Topics: Adaptation, Physiological; Animals; Cell Hypoxia; Drug Resistance, Neoplasm; Humans; Neoplasms; Neov | 2009 |
Glycolysis and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoantigens; Cell Differentiation; Cell Proliferation; Fructose-Bisphosphate | 2011 |
5 other studies available for pyruvic acid and Angiogenesis, Pathologic
| Article | Year |
|---|---|
In vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Contrast Media; Cyclic N-Oxides; Electron Spin R | 2014 |
Voxel-by-voxel correlations of perfusion, substrate, and metabolite signals in dynamic hyperpolarized (13) C imaging.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, | 2016 |
Pyruvate promotes tumor angiogenesis through HIF-1-dependent PAI-1 expression.
Topics: Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Electrophoretic Mobility Shift Assay; | 2011 |
Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy.
Topics: Angiogenesis Inhibitors; Animals; Carbon Isotopes; Contrast Media; Diffusion Magnetic Resonance Imag | 2010 |
Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration.
Topics: Adenosine Triphosphate; Amino Acids; Anoikis; Cell Line, Tumor; Cell Movement; Cell Survival; Citric | 2012 |