pyruvic acid has been researched along with Adenocarcinoma in 11 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Atalay, EB | 1 |
| Kayali, HA | 1 |
| Alasadi, A | 1 |
| Cao, B | 1 |
| Guo, J | 1 |
| Tao, H | 1 |
| Collantes, J | 1 |
| Tan, V | 1 |
| Su, X | 1 |
| Augeri, D | 1 |
| Jin, S | 1 |
| Aggarwal, R | 1 |
| Vigneron, DB | 3 |
| Kurhanewicz, J | 1 |
| Milshteyn, E | 1 |
| von Morze, C | 1 |
| Gordon, JW | 1 |
| Zhu, Z | 1 |
| Larson, PEZ | 1 |
| Mungo, E | 1 |
| Bergandi, L | 1 |
| Salaroglio, IC | 1 |
| Doublier, S | 1 |
| Xing, Y | 1 |
| Reed, GD | 1 |
| Pauly, JM | 2 |
| Kerr, AB | 2 |
| Larson, PE | 2 |
| Wartenberg, M | 1 |
| Richter, M | 1 |
| Datchev, A | 1 |
| Günther, S | 1 |
| Milosevic, N | 1 |
| Bekhite, MM | 1 |
| Figulla, HR | 1 |
| Aran, JM | 1 |
| Pétriz, J | 1 |
| Sauer, H | 1 |
| Witney, TH | 1 |
| Kettunen, MI | 1 |
| Hu, DE | 1 |
| Gallagher, FA | 1 |
| Bohndiek, SE | 1 |
| Napolitano, R | 1 |
| Brindle, KM | 1 |
| Swisher, CL | 1 |
| Stanko, RT | 1 |
| Mullick, P | 1 |
| Clarke, MR | 1 |
| Contis, LC | 1 |
| Janosky, JE | 1 |
| Ramasastry, SS | 1 |
| O'Donnell-Tormey, J | 1 |
| Nathan, CF | 1 |
| Lanks, K | 1 |
| DeBoer, CJ | 1 |
| de la Harpe, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis. A Phase I, Double Blind, Placebo Controlled, Safety Study.[NCT00332215] | Phase 1 | 70 participants (Anticipated) | Interventional | 2006-02-28 | Terminated (stopped due to Dr. Milla has left University of Minnesota. The study is no longer being conducted at this site.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 other studies available for pyruvic acid and Adenocarcinoma
| Article | Year |
|---|---|
The elevated D-2-hydroxyglutarate level found as a characteristic metabolic change of colon cancer in both in vitro and in vivo models.
Topics: Adenocarcinoma; Caco-2 Cells; Colonic Neoplasms; Glucose; Glutarates; Humans; Isocitrate Dehydrogena | 2022 |
Mitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models.
Topics: Adenocarcinoma; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Car | 2021 |
Hyperpolarized 1-[
Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Carbon-13 Magnetic Resonance | 2017 |
High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-
Topics: Adenocarcinoma; Alanine; Animals; Carbon Isotopes; Image Processing, Computer-Assisted; Lactic Acid; | 2018 |
Pyruvate Treatment Restores the Effectiveness of Chemotherapeutic Agents in Human Colon Adenocarcinoma and Pleural Mesothelioma Cells.
Topics: Acrylates; Adenocarcinoma; Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Trans | 2018 |
Optimal variable flip angle schemes for dynamic acquisition of exchanging hyperpolarized substrates.
Topics: Adenocarcinoma; Algorithms; Animals; Biotransformation; Carbon Isotopes; Computer Simulation; Image | 2013 |
Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1 | 2010 |
Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Calcium Dobesilate; Carbon Isotopes; Cell Death; Cell Lin | 2010 |
A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates.
Topics: Adenocarcinoma; Algorithms; Animals; Electromagnetic Fields; Humans; Kinetics; L-Lactate Dehydrogena | 2012 |
Pyruvate inhibits growth of mammary adenocarcinoma 13762 in rats.
Topics: Adenocarcinoma; Animals; DNA Damage; Female; Free Radicals; Lung Neoplasms; Mammary Neoplasms, Exper | 1994 |
Secretion of pyruvate. An antioxidant defense of mammalian cells.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line; Cell Survival; Connective Tissue; Fibroblasts; | 1987 |