pyruvic acid has been researched along with Acute Myelogenous Leukemia in 5 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Tigecycline is relatively unstable after reconstitution, and this instability may limit the use of the drug in ambulatory infusions for the treatment of infection and may prevent the development of optimal dosing schedules for the treatment of AML." | 1.40 | A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. ( Goard, CA; Gronda, M; Hurren, R; Jhas, B; Jitkova, Y; Schimmer, AD; Wang, X, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, Y | 1 |
| Wang, T | 1 |
| Sheng, D | 1 |
| Han, C | 1 |
| Xu, T | 1 |
| Zhang, P | 1 |
| You, W | 1 |
| Fan, W | 1 |
| Zhang, Z | 1 |
| Jin, T | 1 |
| Duan, X | 1 |
| Yuan, X | 1 |
| Liu, X | 1 |
| Zhang, K | 1 |
| Ruan, K | 1 |
| Shi, J | 1 |
| Guo, J | 1 |
| Cheng, A | 1 |
| Yang, Z | 1 |
| Khan, DH | 1 |
| Mullokandov, M | 1 |
| Wu, Y | 1 |
| Voisin, V | 1 |
| Gronda, M | 2 |
| Hurren, R | 2 |
| Wang, X | 2 |
| MacLean, N | 1 |
| Jeyaraju, DV | 1 |
| Jitkova, Y | 2 |
| Xu, GW | 1 |
| Laister, R | 1 |
| Seneviratne, A | 1 |
| Blatman, ZM | 1 |
| Ketela, T | 1 |
| Bader, GD | 1 |
| Marhon, SA | 1 |
| De Carvalho, DD | 1 |
| Minden, MD | 1 |
| Gross, A | 1 |
| Schimmer, AD | 2 |
| Zacharias, NM | 1 |
| Baran, N | 1 |
| Shanmugavelandy, SS | 1 |
| Lee, J | 1 |
| Lujan, JV | 1 |
| Dutta, P | 1 |
| Millward, SW | 1 |
| Cai, T | 1 |
| Wood, CG | 1 |
| Piwnica-Worms, D | 1 |
| Konopleva, M | 1 |
| Bhattacharya, PK | 1 |
| Goard, CA | 1 |
| Jhas, B | 1 |
| Malvoisin, E | 1 |
| Wild, F | 1 |
| Zwingelstein, G | 1 |
5 other studies available for pyruvic acid and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
Topics: Cell Division; Cell Line, Tumor; Glycolysis; Humans; Leukemia, Myeloid, Acute; Phosphorylation; Pyru | 2022 |
Mitochondrial carrier homolog 2 is necessary for AML survival.
Topics: Acetylation; Animals; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; CRISPR-Cas Systems; Feta | 2020 |
Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-Time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia.
Topics: Animals; Benzeneacetamides; Cell Line, Tumor; Cell Proliferation; Cell Survival; HL-60 Cells; Humans | 2019 |
A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity.
Topics: Animals; Anti-Bacterial Agents; Ascorbic Acid; Cell Line, Tumor; Cell Survival; Chromatography, High | 2014 |
Relationship between membrane sterol composition and responsiveness to 12-O-tetradecanoylphorbol 13-acetate in HL-60 human promyelocytic leukaemia cell lines.
Topics: Acetates; Carbon Radioisotopes; Cell Line; Cholesterol; Humans; Lanosterol; Leucine; Leukemia, Myelo | 1988 |