pyruvic acid has been researched along with Acute Disease in 22 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of antiedematous agent with intravenous 10% glycerol on cerebral blood flow (CBF) and metabolism were studied in acute cerebral ischemia experimentally induced by bilateral carotid artery occlusion in spontaneously hypertensive rats (SHR)." | 7.67 | Effects of intravenous glycerol on cerebral blood flow and tissue metabolism in acute cerebral ischemia in spontaneously hypertensive rats. ( Fujishima, M; Ibayashi, S; Ishitsuka, T; Sadoshima, S; Shiokawa, O; Yoshida, F, 1986) |
| "The effects of antiedematous agent with intravenous 10% glycerol on cerebral blood flow (CBF) and metabolism were studied in acute cerebral ischemia experimentally induced by bilateral carotid artery occlusion in spontaneously hypertensive rats (SHR)." | 3.67 | Effects of intravenous glycerol on cerebral blood flow and tissue metabolism in acute cerebral ischemia in spontaneously hypertensive rats. ( Fujishima, M; Ibayashi, S; Ishitsuka, T; Sadoshima, S; Shiokawa, O; Yoshida, F, 1986) |
| "Patients with schizotypal personality disorder (SPD), the prototypic schizophrenia spectrum disorder, do not develop the frank psychosis of schizophrenia and appear clinically to be less reactive to stress than schizophrenic patients." | 2.71 | Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizotypal personality disorder. ( Breier, A; Elman, I; Goodman, M; Iskander, EG; Mitropoulou, V; New, AS; Sevy, S; Siever, LJ; Silverman, JM, 2004) |
| "Patients suffering from acute bacterial meningitis (ABM) with a decreased level of consciousness have been shown to have an improved clinical outcome if treated with an intracranial pressure (ICP) guided therapy." | 1.43 | Neuron-Specific Enolase Is Correlated to Compromised Cerebral Metabolism in Patients Suffering from Acute Bacterial Meningitis; An Observational Cohort Study. ( Bartek, J; Bellander, BM; Ghatan, PH; Glimaker, M; Thelin, EP, 2016) |
| "Hyperglycemia is an indication of poor outcome for heart attack patients, even for nondiabetic patients with stress-induced hyperglycemia." | 1.36 | Cardiac contractile dysfunction during acute hyperglycemia due to impairment of SERCA by polyol pathway-mediated oxidative stress. ( Cheng, WT; Chung, SK; Chung, SS; Hou, XY; Kravtsov, GM; Tang, WH; Tong, XY, 2010) |
| "Compared with normal coronary flow, myocardial hibernation resulted in parallel decreases of 65% and 79% in pyruvate carboxylation and net citrate release by the myocardium, respectively, and maintenance of the CAC intermediate content." | 1.31 | Acute hibernation decreases myocardial pyruvate carboxylation and citrate release. ( Brunengraber, H; Chandler, M; Comte, B; Des Rosiers, C; Dudar, B; Huang, H; Panchal, AR; Roth, B; Stanley, WC, 2001) |
| "Both steroids and hemorrhage may affect the hepatic energy metabolism." | 1.30 | [Effects of steroids on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage]. ( Ikeya, K; Kashimoto, S; Kumazawa, T; Kume, M, 1997) |
| "Glycogen in LR group was higher than that in the control group." | 1.30 | [Effects of lactated Ringer solution and acetated Ringer solution on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage]. ( Ikeya, K; Kashimoto, S; Kumazawa, T; Kume, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Montrazi, ET | 1 |
| Sasson, K | 1 |
| Agemy, L | 1 |
| Peters, DC | 1 |
| Brenner, O | 1 |
| Scherz, A | 1 |
| Frydman, L | 1 |
| Fonouni, H | 1 |
| Golriz, M | 1 |
| Majlesara, A | 1 |
| Faridar, A | 1 |
| Esmaeilzadeh, M | 1 |
| Jarahian, P | 1 |
| Rad, MT | 1 |
| Hafezi, M | 1 |
| Garoussi, C | 1 |
| Macher-Goeppinger, S | 1 |
| Longerich, T | 1 |
| Orakcioglu, B | 1 |
| Sakowitz, OW | 1 |
| Mehrabi, A | 1 |
| Bartek, J | 1 |
| Thelin, EP | 1 |
| Ghatan, PH | 1 |
| Glimaker, M | 1 |
| Bellander, BM | 1 |
| Ziolkowski, W | 1 |
| Wierzba, TH | 1 |
| Kaczor, JJ | 1 |
| Olek, RA | 1 |
| Wozniak, M | 1 |
| Kmieć, Z | 1 |
| Myśliwski, A | 1 |
| Antosiewicz, J | 1 |
| Hartley, CE | 1 |
| Varma, M | 1 |
| Fischer, JP | 1 |
| Riccardi, R | 1 |
| Strauss, JA | 1 |
| Shah, S | 1 |
| Zhang, S | 1 |
| Yang, ZJ | 1 |
| Tang, WH | 1 |
| Cheng, WT | 1 |
| Kravtsov, GM | 1 |
| Tong, XY | 1 |
| Hou, XY | 1 |
| Chung, SK | 1 |
| Chung, SS | 1 |
| Mitropoulou, V | 1 |
| Goodman, M | 1 |
| Sevy, S | 1 |
| Elman, I | 1 |
| New, AS | 1 |
| Iskander, EG | 1 |
| Silverman, JM | 1 |
| Breier, A | 1 |
| Siever, LJ | 1 |
| Vespa, P | 1 |
| Bergsneider, M | 1 |
| Hattori, N | 1 |
| Wu, HM | 1 |
| Huang, SC | 1 |
| Martin, NA | 1 |
| Glenn, TC | 1 |
| McArthur, DL | 1 |
| Hovda, DA | 1 |
| Cicalese, L | 1 |
| Hierholzer, C | 1 |
| Subbotin, V | 1 |
| Iyengar, A | 1 |
| Rao, AS | 1 |
| Stanko, RT | 1 |
| Ikeya, K | 3 |
| Kashimoto, S | 3 |
| Kume, M | 3 |
| Kumazawa, T | 3 |
| Ekberg, K | 1 |
| Fernqvist-Forbes, E | 1 |
| Nair, S | 1 |
| Kiefer, P | 1 |
| Nunes, S | 1 |
| Kosonen, P | 1 |
| Takala, J | 1 |
| Joon, SJ | 1 |
| Panchal, AR | 1 |
| Comte, B | 1 |
| Huang, H | 1 |
| Dudar, B | 1 |
| Roth, B | 1 |
| Chandler, M | 1 |
| Des Rosiers, C | 1 |
| Brunengraber, H | 1 |
| Stanley, WC | 1 |
| Szczepaniak, S | 3 |
| Nowiński, H | 1 |
| Jeleniewicz, K | 3 |
| Maciejewska-Kozak, H | 1 |
| Sadeghi, AM | 1 |
| Breda, MA | 1 |
| Laks, H | 1 |
| Chang, PA | 1 |
| Laidig, CA | 1 |
| Wu, A | 1 |
| Bhuta, S | 1 |
| Drinkwater, DC | 1 |
| Kimura, A | 1 |
| Yoshida, I | 1 |
| Ono, E | 1 |
| Matsuishi, T | 1 |
| Yoshino, M | 1 |
| Yamashita, F | 1 |
| Yamamoto, M | 1 |
| Hashimoto, T | 1 |
| Shinka, T | 1 |
| Kuhara, T | 1 |
| Fujishima, M | 1 |
| Ishitsuka, T | 1 |
| Yoshida, F | 1 |
| Ibayashi, S | 1 |
| Shiokawa, O | 1 |
| Sadoshima, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Exogenous Sodium Lactate Infusion in Traumatic Brain Injury (ELI-TBI)[NCT02776488] | Phase 2 | 0 participants (Actual) | Interventional | 2020-09-30 | Withdrawn (stopped due to The manufacturer of sodium lactate has stopped making the medication) | ||
| Cerebral Blood Flow (CBF) Disturbances Following Traumatic Brain Injury (TBI) and Subarachnoid Hemorrhage (SAH)[NCT00807833] | 20 participants (Actual) | Observational | 2009-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for pyruvic acid and Acute Disease
| Article | Year |
|---|---|
Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizotypal personality disorder.
Topics: Acute Disease; Adult; Antimetabolites; Deoxyglucose; Dopamine; Double-Blind Method; Drug Administrat | 2004 |
Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study.
Topics: Acute Disease; Adolescent; Adult; Brain Injuries; Brain Ischemia; Glucose; Humans; Incidence; Lactic | 2005 |
Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study.
Topics: Acute Disease; Adolescent; Adult; Brain Injuries; Brain Ischemia; Glucose; Humans; Incidence; Lactic | 2005 |
Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study.
Topics: Acute Disease; Adolescent; Adult; Brain Injuries; Brain Ischemia; Glucose; Humans; Incidence; Lactic | 2005 |
Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study.
Topics: Acute Disease; Adolescent; Adult; Brain Injuries; Brain Ischemia; Glucose; Humans; Incidence; Lactic | 2005 |
20 other studies available for pyruvic acid and Acute Disease
| Article | Year |
|---|---|
High-sensitivity deuterium metabolic MRI differentiates acute pancreatitis from pancreatic cancers in murine models.
Topics: Acute Disease; Animals; Deuterium; Disease Models, Animal; Humans; Lactic Acid; Magnetic Resonance I | 2023 |
Is microdialysis useful for early detection of acute rejection after kidney transplantation?
Topics: Acute Disease; Animals; Biomarkers; Disease Models, Animal; Early Diagnosis; Glucose; Glycerol; Graf | 2015 |
Neuron-Specific Enolase Is Correlated to Compromised Cerebral Metabolism in Patients Suffering from Acute Bacterial Meningitis; An Observational Cohort Study.
Topics: Acute Disease; Adolescent; Adult; Aged; Biomarkers; Brain; Cohort Studies; Female; Glucose; Humans; | 2016 |
Intravenous sodium pyruvate protects against cerulein-induced acute pancreatitis.
Topics: Acute Disease; Animals; Antioxidants; Ceruletide; Male; Oxidative Stress; Pancreatitis; Pyruvic Acid | 2008 |
Neuroprotective effects of erythropoietin on acute metabolic and pathological changes in experimentally induced neurotrauma.
Topics: Acute Disease; Animals; Brain Injuries; Disease Models, Animal; Energy Metabolism; Erythropoietin; G | 2008 |
Cardiac contractile dysfunction during acute hyperglycemia due to impairment of SERCA by polyol pathway-mediated oxidative stress.
Topics: Acute Disease; Aldehyde Reductase; Animals; Calcium Signaling; Glucose; Glutathione; Heart; Hypergly | 2010 |
Protective effect of pyruvate during acute rejection of intestinal allografts: accompanied by up-regulation of inducible nitric oxide synthase mRNA.
Topics: Acute Disease; Animals; Apoptosis; Enzyme Induction; Graft Rejection; Intestine, Small; Male; Nitric | 1997 |
[Effects of steroids on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acidosis, Lactic; Acute Disease; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Glycogen | 1997 |
[Effects of lactated Ringer solution and acetated Ringer solution on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acute Disease; Adenosine Triphosphate; Animals; Glycogen; Hemorrhage; Isotonic Solutions; Lactic Aci | 1998 |
[Effects of hypertonic lactated Ringer's solution on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acute Disease; Adenosine Triphosphate; Animals; Energy Metabolism; Glycogen; Hemorrhage; Hypertonic | 1998 |
Brain substrate utilisation during acute hypoglycaemia.
Topics: Acute Disease; Adult; Amino Acids; Blood Glucose; Brain; Glucose Clamp Technique; Humans; Hypoglycem | 1999 |
Effect of positive end-expiratory pressure on splanchnic perfusion in acute lung injury.
Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Indocyanine Green | 2000 |
[Acute effect of 7% CO2 breathing on lactate, pyruvate and ketone body metabolism in healthy subjects].
Topics: Acute Disease; Adult; Carbon Dioxide; Energy Metabolism; Female; Humans; Hypercapnia; Ketone Bodies; | 2001 |
Acute hibernation decreases myocardial pyruvate carboxylation and citrate release.
Topics: Acute Disease; Animals; Citric Acid; Decarboxylation; Malate Dehydrogenase; Myocardial Stunning; Osm | 2001 |
[Pyruvic acid in the rat liver and myocardium after acute chlorfenvinphos poisoning].
Topics: Acute Disease; Animals; Chlorfenvinphos; Disease Models, Animal; Heart; Liver; Male; Myocardium; Pyr | 1991 |
[Effect of acute carbaryl poisoning of rats on transamination reactions with the participation of pyruvic acid].
Topics: Acute Disease; Amino Acids; Animals; Carbaryl; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Str | 1987 |
Effects of acute hypoxia and reoxygenation in a blood-perfused neonatal heart model.
Topics: Acute Disease; Animals; Animals, Newborn; Blood; Energy Metabolism; Heart; Hypoxia; Lactates; Lactic | 1988 |
Acute encephalopathy with hyperammonemia and dicarboxylic aciduria during calcium hopantenate therapy: a patient report.
Topics: Acute Disease; Ammonia; Brain Diseases; Child, Preschool; Female; gamma-Aminobutyric Acid; Humans; P | 1986 |
[Effect of acute carbaryl poisoning on pyruvic acid and total keto acid levels in the blood of rats].
Topics: Acute Disease; Animals; Carbaryl; Erythrocytes; Keto Acids; Male; Pyruvates; Pyruvic Acid; Rats; Rat | 1985 |
Effects of intravenous glycerol on cerebral blood flow and tissue metabolism in acute cerebral ischemia in spontaneously hypertensive rats.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; | 1986 |