pyruvic acid has been researched along with Acquired Metabolic Diseases, Brain in 15 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The disorders causing myoclonus have been compared to those in which myoclonus has been reported." | 2.37 | Myoclonus and mitochondrial myopathy. ( Hopkins, LC; Rosing, HS, 1986) |
| "The majority of patients with PDHC deficiency have abnormalities in the major catalytic and regulatory subunit, E1 alpha, which is encoded on the X chromosome." | 1.29 | Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency. ( Arnold, DL; Brown, GK; Brown, RM; Legris, M; Matthews, PM; Otero, LJ; Scriver, CR; Shevell, MI, 1994) |
| "Two new patients with Leigh's syndrome (subacute necrotizing encephalomyelopathy) due to deficiency of cytochrome c oxidase are presented and their data are compared with those of the four Leigh's syndrome patients previously reported with this deficiency." | 1.27 | Cytochrome c oxidase deficiency in subacute necrotizing encephalomyelopathy. ( Arts, WF; Fernandes, J; Loonen, MC; Luyt-Houwen, IE; Przyrembel, H; Scholte, HR; Trijbels, JM, 1987) |
| "Leigh's disease is a subacute metabolic encephalopathy characterized by bilateral and symmetrical lesions of basal ganglia, mid-brain and pons." | 1.27 | [Subacute necrotizing encephalopathy, Leigh's disease. Apropos of a case]. ( Bouissou, H; Delisle, MB; Netter, JC; Peyrille, F, 1985) |
| "We studied a 17-year-old girl with subacute necrotizing encephalomyelopathy (Leigh syndrome)." | 1.27 | Subacute necrotizing encephalomyelopathy (Leigh syndrome) associated with disturbed oxidation of pyruvate, malate and 2-oxoglutarate in muscle and liver. ( Den Hartog, MR; Fischer, JC; Gabreëls, FJ; Janssen, AJ; Renier, WO; Ruitenbeek, W; Slooff, JL; Trijbels, JM; Van Erven, PM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mayr, JA | 1 |
| Freisinger, P | 1 |
| Schlachter, K | 1 |
| Rolinski, B | 1 |
| Zimmermann, FA | 1 |
| Scheffner, T | 1 |
| Haack, TB | 1 |
| Koch, J | 1 |
| Ahting, U | 1 |
| Prokisch, H | 1 |
| Sperl, W | 1 |
| Stein, NR | 1 |
| McArthur, DL | 1 |
| Etchepare, M | 1 |
| Vespa, PM | 1 |
| KLEEBERG, J | 1 |
| GITELSON, S | 1 |
| Shevell, MI | 1 |
| Matthews, PM | 1 |
| Scriver, CR | 1 |
| Brown, RM | 1 |
| Otero, LJ | 1 |
| Legris, M | 1 |
| Brown, GK | 1 |
| Arnold, DL | 1 |
| Sunohara, N | 1 |
| van Erven, PM | 4 |
| Renier, WO | 4 |
| Gabreëls, FJ | 4 |
| Thijssen, HO | 1 |
| Ruitenbeek, W | 4 |
| Horstink, MW | 1 |
| Harigaya, Y | 1 |
| Shoji, M | 1 |
| Okamoto, K | 1 |
| Hirai, S | 1 |
| Sato, T | 1 |
| Arts, WF | 1 |
| Scholte, HR | 1 |
| Loonen, MC | 1 |
| Przyrembel, H | 1 |
| Fernandes, J | 1 |
| Trijbels, JM | 2 |
| Luyt-Houwen, IE | 1 |
| Hopkins, LC | 1 |
| Rosing, HS | 1 |
| Ohama, E | 1 |
| Ikuta, F | 1 |
| Nakamura, N | 1 |
| Lamers, KJ | 2 |
| Sloof, JL | 1 |
| Wevers, RA | 1 |
| Doesburg, WH | 1 |
| Delisle, MB | 1 |
| Netter, JC | 1 |
| Peyrille, F | 1 |
| Bouissou, H | 1 |
| Siemes, H | 1 |
| Den Hartog, MR | 1 |
| Fischer, JC | 1 |
| Slooff, JL | 1 |
| Janssen, AJ | 1 |
2 reviews available for pyruvic acid and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
Myoclonus and mitochondrial myopathy.
Topics: Adolescent; Brain Diseases, Metabolic; Central Nervous System Diseases; Electroencephalography; Epil | 1986 |
Mitochondrial abnormalities in choroid plexus of Leigh disease.
Topics: Brain Diseases, Metabolic; Child; Child, Preschool; Choroid Plexus; Female; Humans; Infant; Lactates | 1988 |
13 other studies available for pyruvic acid and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
Thiamine pyrophosphokinase deficiency in encephalopathic children with defects in the pyruvate oxidation pathway.
Topics: Abnormalities, Multiple; Acidosis, Lactic; Adolescent; Amino Acid Sequence; Base Sequence; Brain Dis | 2011 |
Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation.
Topics: Adult; Blood Pressure; Brain; Brain Diseases, Metabolic; Brain Injuries; Cardiopulmonary Resuscitati | 2012 |
The blood pyruvic acid level in renal diseases and in uraemic coma.
Topics: Blood; Brain Diseases, Metabolic; Coma; Humans; Kidney Diseases; Pyruvates; Pyruvic Acid; Uremia | 1956 |
Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency.
Topics: Acidosis, Lactic; Agenesis of Corpus Callosum; Brain; Brain Damage, Chronic; Brain Diseases, Metabol | 1994 |
[Leigh's syndrome].
Topics: Brain Diseases, Metabolic; Cytochrome-c Oxidase Deficiency; Electron Transport; Electron Transport C | 1990 |
Hypokinesia and rigidity as clinical manifestations of mitochondrial encephalomyopathy: report of three cases.
Topics: Adolescent; Atrophy; Brain; Brain Diseases, Metabolic; Child; Child Development; Follow-Up Studies; | 1989 |
[A case of mitochondrial encephalomyopathy with myoclonic attacks, hyper-lactic-pyruvic acidemia, and decreased activities of complex II and cytochrome c oxidase].
Topics: Adult; Brain Diseases, Metabolic; Electron Transport Complex II; Electron Transport Complex IV; Huma | 1988 |
Cytochrome c oxidase deficiency in subacute necrotizing encephalomyelopathy.
Topics: Brain; Brain Diseases, Metabolic; Child; Child, Preschool; Cytochrome-c Oxidase Deficiency; Electron | 1987 |
Familial Leigh's syndrome: association with a defect in oxidative metabolism probably restricted to brain.
Topics: Adolescent; Adult; Brain; Brain Diseases, Metabolic; Female; Humans; Lactates; Leigh Disease; Malate | 1987 |
Intravenous pyruvate loading test in Leigh syndrome.
Topics: Brain Diseases, Metabolic; Cells, Cultured; Citric Acid Cycle; Fibroblasts; Humans; Leigh Disease; O | 1987 |
[Subacute necrotizing encephalopathy, Leigh's disease. Apropos of a case].
Topics: Brain; Brain Diseases, Metabolic; Child, Preschool; Humans; Leigh Disease; Male; Mitochondria, Heart | 1985 |
[Mitochondrial myopathies and encephalomyopathies. Neuromuscular and central nervous system diseases caused by defects in mitochondrial oxidative metabolism].
Topics: Brain; Brain Diseases, Metabolic; Carnitine O-Acetyltransferase; Child; Citric Acid Cycle; Cytochrom | 1985 |
Subacute necrotizing encephalomyelopathy (Leigh syndrome) associated with disturbed oxidation of pyruvate, malate and 2-oxoglutarate in muscle and liver.
Topics: Adolescent; Brain; Brain Diseases, Metabolic; Enzymes; Female; Humans; Ketoglutaric Acids; Lactates; | 1985 |