pyruvaldehyde has been researched along with Vascular Diseases in 7 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glo-1 has a dual role in cancer as a tumour suppressor protein prior to tumour development and mediator of multi-drug resistance in cancer treatment, implicating dicarbonyl glycation of DNA in carcinogenesis and dicarbonyl-driven cytotoxicity in mechanism of action of anticancer drugs." | 2.53 | Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics. ( Rabbani, N; Thornalley, PJ; Xue, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Nomiyama, T | 1 |
| Rabbani, N | 1 |
| Xue, M | 1 |
| Thornalley, PJ | 1 |
| Nigro, C | 1 |
| Leone, A | 1 |
| Raciti, GA | 1 |
| Longo, M | 1 |
| Mirra, P | 1 |
| Formisano, P | 1 |
| Beguinot, F | 1 |
| Miele, C | 1 |
| Cai, W | 1 |
| Torreggiani, M | 1 |
| Zhu, L | 1 |
| Chen, X | 1 |
| He, JC | 1 |
| Striker, GE | 1 |
| Vlassara, H | 1 |
| Dhar, A | 2 |
| Dhar, I | 2 |
| Desai, KM | 1 |
| Wu, L | 2 |
| Titov, VN | 1 |
| Shiriaeva, IuK | 1 |
| Desai, K | 1 |
2 reviews available for pyruvaldehyde and Vascular Diseases
| Article | Year |
|---|---|
Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics.
Topics: Aging; Animals; Dyslipidemias; Glycation End Products, Advanced; Humans; Lactoylglutathione Lyase; N | 2016 |
Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage.
Topics: Animals; Endothelium, Vascular; Humans; Insulin Resistance; Lactoylglutathione Lyase; Models, Biolog | 2017 |
5 other studies available for pyruvaldehyde and Vascular Diseases
| Article | Year |
|---|---|
Can SGLT2 Inhibitor be Used for Diabetes Mellitus or Vascular Diseases?
Topics: Animals; Atherosclerosis; Blood Glucose; Canagliflozin; Clinical Trials as Topic; Diabetes Mellitus; | 2020 |
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.
Topics: Active Transport, Cell Nucleus; Age Factors; Animals; Cell Line; Endothelial Cells; ErbB Receptors; | 2010 |
Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose.
Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Cells, Cultured; Cyclic GMP; Endothelial Cells; Gluco | 2010 |
[The glucose, glycotoxins and glycation products: the involvement into pathogenesis of microangiopathies, arteriolosclerosis and atherosclerosis].
Topics: Arteriolosclerosis; Atherosclerosis; Diabetes Mellitus; Diabetic Angiopathies; Glucose; Glutamic Aci | 2011 |
Arginine attenuates methylglyoxal- and high glucose-induced endothelial dysfunction and oxidative stress by an endothelial nitric-oxide synthase-independent mechanism.
Topics: Animals; Aorta; Arginase; Arginine; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Gluco | 2012 |