pyruvaldehyde has been researched along with Prostatic Neoplasms in 5 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Prostatic Neoplasms: Tumors or cancer of the PROSTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylglyoxal is one of the most powerful glycating agents of proteins and other important cellular components and has been shown to be toxic to cultured cells." | 1.39 | A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cells. ( Antognelli, C; Fettucciari, K; Mezzasoma, L; Talesa, VN, 2013) |
| "MG is capable of inducing apoptosis in prostatic cancer PC-3 cells, due primarily to a blocking of the cell cycle progression (G(1) arrest) and glycolytic pathway." | 1.31 | Methylglyoxal-induced apoptosis in human prostate carcinoma: potential modality for prostate cancer treatment. ( Choudhury, MS; Konno, S; Mallouh, C; Milanesa, DM; Tazaki, H, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mir, AR | 1 |
| Habib, S | 1 |
| Khan, F | 1 |
| Alam, K | 1 |
| Ali, A | 1 |
| Antognelli, C | 2 |
| Mezzasoma, L | 1 |
| Fettucciari, K | 1 |
| Talesa, VN | 1 |
| Del Buono, C | 1 |
| Baldracchini, F | 1 |
| Talesa, V | 1 |
| Cottini, E | 1 |
| Brancadoro, C | 1 |
| Zucchi, A | 1 |
| Mearini, E | 1 |
| Milanesa, DM | 2 |
| Choudhury, MS | 2 |
| Mallouh, C | 2 |
| Tazaki, H | 2 |
| Konno, S | 2 |
| Davidson, SD | 1 |
5 other studies available for pyruvaldehyde and Prostatic Neoplasms
| Article | Year |
|---|---|
Structural changes in histone H2A by methylglyoxal generate highly immunogenic amorphous aggregates with implications in auto-immune response in cancer.
Topics: Adolescent; Adult; Animals; Antibodies, Neoplasm; Autoantibodies; Case-Control Studies; Epitopes; Fe | 2016 |
A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cells.
Topics: Amino Acid Sequence; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cytoskeleton; Gene Silencin | 2013 |
Alteration of glyoxalase genes expression in response to testosterone in LNCaP and PC3 human prostate cancer cells.
Topics: Adenocarcinoma; Androgens; Aromatase Inhibitors; Base Sequence; Cell Line, Tumor; Enzyme Induction; | 2007 |
Methylglyoxal-induced apoptosis in human prostate carcinoma: potential modality for prostate cancer treatment.
Topics: Apoptosis; Cell Division; Drug Screening Assays, Antitumor; Glycolysis; Humans; Male; Prostatic Neop | 2000 |
A possible regulatory role of glyoxalase I in cell viability of human prostate cancer.
Topics: Acetylcysteine; Cell Survival; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycoly | 2002 |