pyruvaldehyde has been researched along with Pregnancy in 19 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a diabetic pregnancy, an altered maternal metabolism led to increased formation of reactive α-dicarbonyls such as glyoxal (GO) and methylglyoxal (MGO) in the reproductive organs and embryos." | 3.91 | Glyoxalase 1 expression is downregulated in preimplantation blastocysts of diabetic rabbits. ( Grybel, KJ; Gürke, J; Haucke, E; Navarrete Santos, A; Pendzialek, SM; Schindler, M; Seeling, T; Simm, A, 2019) |
| " Maternal plasma glucose and methylgyoxal concentrations, as well as embryonic N(ε)-carboxymethyl-lysine (CML) levels were increased to the same extent in diabetic WT and RAGE(-/-) pregnancy." | 3.83 | Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy. ( Brings, S; Ejdesjö, A; Eriksson, UJ; Fleming, T; Fred, RG; Nawroth, PP, 2016) |
| "Autism is a complex and heterogeneous neurodevelopmental disorder of unknown etiology but very likely resulting from both genetic and environmental factors." | 1.38 | Methylglyoxal, advanced glycation end products and autism: is there a connection? ( Maher, P, 2012) |
| "Preeclampsia is characterized by vascular endothelial dysfunction partly attributed to oxidative stress." | 1.35 | Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase. ( Davidge, ST; Jiang, Y; Sankaralingam, S; Sawamura, T; Xu, H, 2009) |
| "To assess the role of dAGE on type 1 diabetes, NOD mice were exposed to a high-AGE diet (H-AGE) and to a nutritionally similar diet with approximate fivefold-lower levels of N(epsilon)-carboxymethyllysine (CML) and methylglyoxal-derivatives (MG) (L-AGE)." | 1.32 | Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice. ( Hattori, M; He, C; McEvoy, R; Peppa, M; Vlassara, H; Zheng, F, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Di Martino, D | 1 |
| Cappelletti, M | 1 |
| Tondo, M | 1 |
| Basello, K | 1 |
| Garbin, C | 1 |
| Speciani, A | 1 |
| Ferrazzi, E | 1 |
| Sana, SRGL | 1 |
| Lv, Y | 1 |
| Chen, G | 1 |
| Guo, L | 1 |
| Li, E | 1 |
| Rodrigo, S | 1 |
| Panadero, MI | 1 |
| Fauste, E | 1 |
| Rodríguez, L | 1 |
| Roglans, N | 1 |
| Álvarez-Millán, JJ | 1 |
| Otero, P | 1 |
| Laguna, JC | 1 |
| Bocos, C | 1 |
| Seeling, T | 1 |
| Haucke, E | 1 |
| Navarrete Santos, A | 2 |
| Grybel, KJ | 1 |
| Gürke, J | 1 |
| Pendzialek, SM | 1 |
| Schindler, M | 1 |
| Simm, A | 1 |
| Francisco, FA | 2 |
| Saavedra, LPJ | 2 |
| Junior, MDF | 1 |
| Barra, C | 1 |
| Matafome, P | 1 |
| Mathias, PCF | 2 |
| Gomes, RM | 2 |
| Ejdesjö, A | 1 |
| Brings, S | 1 |
| Fleming, T | 1 |
| Fred, RG | 1 |
| Nawroth, PP | 1 |
| Eriksson, UJ | 2 |
| Barella, LF | 1 |
| Silveira, SDS | 1 |
| Prates, KV | 1 |
| Alves, VS | 1 |
| Franco, CCDS | 1 |
| Miranda, RA | 1 |
| Ribeiro, TA | 1 |
| Tófolo, LP | 1 |
| Malta, A | 1 |
| Vieira, E | 1 |
| Palma-Rigo, K | 1 |
| Pavanello, A | 1 |
| Martins, IP | 1 |
| Moreira, VM | 1 |
| de Oliveira, JC | 1 |
| Yang, G | 1 |
| Cancino, GI | 1 |
| Zahr, SK | 1 |
| Guskjolen, A | 1 |
| Voronova, A | 1 |
| Gallagher, D | 1 |
| Frankland, PW | 1 |
| Kaplan, DR | 1 |
| Miller, FD | 1 |
| Sankaralingam, S | 1 |
| Xu, H | 1 |
| Jiang, Y | 1 |
| Sawamura, T | 1 |
| Davidge, ST | 1 |
| Brouwers, O | 1 |
| Niessen, PM | 1 |
| Ferreira, I | 1 |
| Miyata, T | 1 |
| Scheffer, PG | 1 |
| Teerlink, T | 1 |
| Schrauwen, P | 1 |
| Brownlee, M | 1 |
| Stehouwer, CD | 1 |
| Schalkwijk, CG | 1 |
| Huang, FJ | 1 |
| Chin, TY | 1 |
| Chan, WH | 1 |
| Maher, P | 1 |
| Williams, MA | 1 |
| Enquobahrie, DA | 1 |
| Zimmer, J | 1 |
| Qiu, CF | 1 |
| Hevner, K | 1 |
| Abetew, D | 1 |
| Christianson, C | 1 |
| Sheaff, C | 1 |
| Peppa, M | 1 |
| He, C | 1 |
| Hattori, M | 1 |
| McEvoy, R | 1 |
| Zheng, F | 1 |
| Vlassara, H | 1 |
| Chueh, SH | 1 |
| Chang, GG | 1 |
| Chang, TC | 1 |
| Pan, F | 1 |
| Wentzel, P | 1 |
| Minhas, HS | 1 |
| Thornalley, PJ | 1 |
| Chang, WC | 1 |
| Hsieh, YY | 1 |
| Cheng, TC | 1 |
| Chang, CC | 1 |
| Tsai, HD | 1 |
| Lee, MS | 1 |
| Peters, MA | 1 |
| Hudson, PM | 1 |
| Jurgelske, W | 1 |
| Vander Jagt, DL | 1 |
| Robinson, B | 1 |
| Taylor, KK | 1 |
| Hunsaker, LA | 1 |
1 review available for pyruvaldehyde and Pregnancy
| Article | Year |
|---|---|
Early AGEing and metabolic diseases: is perinatal exposure to glycotoxins programming for adult-life metabolic syndrome?
Topics: Aging; Animals; Female; Fetus; Glycation End Products, Advanced; Humans; Infant; Infant, Newborn; In | 2021 |
18 other studies available for pyruvaldehyde and Pregnancy
| Article | Year |
|---|---|
Glycation-Driven Inflammation: COVID-19 Severity in Pregnant Women and Perinatal Outcomes.
Topics: COVID-19; Female; Glucose; Glycosylation; Humans; Infant, Newborn; Inflammation; Obesity; Overweight | 2022 |
Analysis of the volatile organic compounds of epidural analgesia-ameliorated metabolic disorder in pregnant women with gestational diabetes mellitus based on untargeted metabolomics.
Topics: Analgesia, Epidural; Diabetes, Gestational; Female; Humans; Interleukin-6; Magnesium Oxide; Metabolo | 2023 |
Effects of Maternal Fructose Intake on Perinatal ER-Stress: A Defective XBP1s Nuclear Translocation Affects the ER-stress Resolution.
Topics: Animals; Biological Transport; Cell Nucleus; Diet; Dietary Sugars; Endoplasmic Reticulum; Endoplasmi | 2019 |
Glyoxalase 1 expression is downregulated in preimplantation blastocysts of diabetic rabbits.
Topics: Animals; Blastocyst; Cell Line; Diabetes Mellitus, Experimental; Female; Glyoxal; Humans; Hyperglyce | 2019 |
Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dinoprost; Embryo, Mammalian; Embryonic Dev | 2016 |
Methylglyoxal treatment in lactating mothers leads to type 2 diabetes phenotype in male rat offspring at adulthood.
Topics: Adiposity; Administration, Oral; Animals; Diabetes Mellitus, Type 2; Dyslipidemias; Environmental Po | 2018 |
A Glo1-Methylglyoxal Pathway that Is Perturbed in Maternal Diabetes Regulates Embryonic and Adult Neural Stem Cell Pools in Murine Offspring.
Topics: Adult Stem Cells; Animals; Animals, Newborn; Behavior, Animal; Cerebral Cortex; Diabetes Mellitus, E | 2016 |
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Topics: Adult; Arginase; Arteries; Case-Control Studies; Cells, Cultured; Endothelium, Vascular; Female; Glu | 2009 |
Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats.
Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Gene Expressio | 2011 |
Resveratrol protects against methylglyoxal-induced apoptosis and disruption of embryonic development in mouse blastocysts.
Topics: Animals; Antioxidants; Apoptosis; Blastocyst; Caspase 3; Cell Proliferation; Embryonic Development; | 2013 |
Methylglyoxal, advanced glycation end products and autism: is there a connection?
Topics: Autistic Disorder; Female; Glutathione; Glycation End Products, Advanced; Humans; Models, Biological | 2012 |
Maternal plasma advanced glycation end products concentrations in response to oral 50-gram glucose load in mid-pregnancy: a pilot study.
Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Female; Glucose; Glucose Tolerance Test; Glyc | 2012 |
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice.
Topics: Administration, Oral; Aging; Albuminuria; Animals; Animals, Newborn; Blood Glucose; Creatinine; Cros | 2003 |
Involvement of arginine residue in the phosphate binding site of human placental alkaline phosphatase.
Topics: Alkaline Phosphatase; Arginine; Binding Sites; Diacetyl; Female; Humans; In Vitro Techniques; Kineti | 1981 |
Teratogenicity of 3-deoxyglucosone and diabetic embryopathy.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Embryo, Ma | 1998 |
Effect of methylglyoxal on mouse embryogenesis.
Topics: Animals; Blastocyst; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Mice | 2001 |
The acute toxicity of methylglyoxal in rats: the influence of age, sex, and pregnancy.
Topics: Aging; Aldehydes; Animals; Animals, Newborn; Female; Gestational Age; Intubation, Gastrointestinal; | 1978 |
Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications.
Topics: Acetone; Aldehyde Reductase; Diabetes Complications; Diabetes Mellitus; Female; Glucose; Humans; Kin | 1992 |