pyruvaldehyde has been researched along with Parkinsonian Disorders in 4 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recently, the Parkinsonism-associated protein DJ-1 has been reported to exhibit deglycase activity that erases early glycation intermediates and stable AGEs from proteins." | 1.91 | Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation. ( Gao, Q; Jacob-Dolan, JW; Scheck, RA, 2023) |
| "We discovered recently that Parkinsonism-associated DJ-1 and its bacterial homologs function as protein deglycases that repair glyoxal- and methylglyoxal-glycated proteins." | 1.46 | Parkinsonism-associated protein DJ-1 is a bona fide deglycase. ( Dairou, J; Richarme, G, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, Q | 1 |
| Jacob-Dolan, JW | 1 |
| Scheck, RA | 1 |
| Richarme, G | 2 |
| Mihoub, M | 1 |
| Dairou, J | 2 |
| Bui, LC | 1 |
| Leger, T | 1 |
| Lamouri, A | 1 |
| Deng, Y | 1 |
| Zhang, Y | 1 |
| Li, Y | 1 |
| Xiao, S | 1 |
| Song, D | 1 |
| Qing, H | 1 |
| Li, Q | 1 |
| Rajput, AH | 1 |
4 other studies available for pyruvaldehyde and Parkinsonian Disorders
| Article | Year |
|---|---|
Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation.
Topics: Glycation End Products, Advanced; Glyoxal; Humans; Magnesium Oxide; Maillard Reaction; Parkinsonian | 2023 |
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.
Topics: Acetylcysteine; Albumins; Apoptosis; Arginine; Aspartate Aminotransferases; Catalysis; Cell Survival | 2015 |
Parkinsonism-associated protein DJ-1 is a bona fide deglycase.
Topics: Acetylcysteine; Artifacts; Culture Media; Cysteine; Escherichia coli; Glucose; Glycation End Product | 2017 |
Occurrence and distribution of salsolinol-like compound, 1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (ADTIQ) in parkinsonian brains.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Brain; Chromatography, High Pressure Liquid; Dopamine | 2012 |