pyruvaldehyde has been researched along with Pain in 4 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bortezomib is a first-line chemotherapeutic drug widely used for multiple myeloma and other nonsolid malignancies." | 5.46 | Activation of RAGE/STAT3 pathway by methylglyoxal contributes to spinal central sensitization and persistent pain induced by bortezomib. ( Ding, HH; Lei, WL; Liu, CC; Liu, M; Ma, C; Ouyang, HD; Wei, JY; Wu, SL; Xie, MX; Xin, WJ, 2017) |
| "Bortezomib is a first-line chemotherapeutic drug widely used for multiple myeloma and other nonsolid malignancies." | 1.46 | Activation of RAGE/STAT3 pathway by methylglyoxal contributes to spinal central sensitization and persistent pain induced by bortezomib. ( Ding, HH; Lei, WL; Liu, CC; Liu, M; Ma, C; Ouyang, HD; Wei, JY; Wu, SL; Xie, MX; Xin, WJ, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Almeida, GRL | 1 |
| Szczepanik, JC | 1 |
| Selhorst, I | 1 |
| Cunha, MP | 1 |
| Dafre, AL | 1 |
| Wei, JY | 1 |
| Liu, CC | 1 |
| Ouyang, HD | 1 |
| Ma, C | 1 |
| Xie, MX | 1 |
| Liu, M | 1 |
| Lei, WL | 1 |
| Ding, HH | 1 |
| Wu, SL | 1 |
| Xin, WJ | 1 |
| Barragán-Iglesias, P | 1 |
| Kuhn, J | 1 |
| Vidal-Cantú, GC | 1 |
| Salinas-Abarca, AB | 1 |
| Granados-Soto, V | 1 |
| Dussor, GO | 1 |
| Campbell, ZT | 1 |
| Price, TJ | 1 |
| Brings, S | 1 |
| Fleming, T | 1 |
| De Buhr, S | 1 |
| Beijer, B | 1 |
| Lindner, T | 1 |
| Wischnjow, A | 1 |
| Kender, Z | 1 |
| Peters, V | 1 |
| Kopf, S | 1 |
| Haberkorn, U | 1 |
| Mier, W | 1 |
| Nawroth, PP | 1 |
1 review available for pyruvaldehyde and Pain
| Article | Year |
|---|---|
The expanding impact of methylglyoxal on behavior-related disorders.
Topics: Arginine; Cysteine; Dopamine; Glycation End Products, Advanced; Humans; Lysine; Magnesium Oxide; Men | 2023 |
3 other studies available for pyruvaldehyde and Pain
| Article | Year |
|---|---|
Activation of RAGE/STAT3 pathway by methylglyoxal contributes to spinal central sensitization and persistent pain induced by bortezomib.
Topics: Animals; Antineoplastic Agents; Bortezomib; Central Nervous System Sensitization; Disease Models, An | 2017 |
Activation of the integrated stress response in nociceptors drives methylglyoxal-induced pain.
Topics: Analgesics, Non-Narcotic; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA-Bind | 2019 |
A scavenger peptide prevents methylglyoxal induced pain in mice.
Topics: Amino Acid Sequence; Analgesics; Animals; Mice; Mice, Inbred C57BL; Pain; Peptides, Cyclic; Pyruvald | 2017 |