Page last updated: 2024-10-19

pyruvaldehyde and Osteoarthritis

pyruvaldehyde has been researched along with Osteoarthritis in 2 studies

Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
"A role for inflammation is thought to be integral to the pathology."2.50Possible role of methylglyoxal and glyoxalase in arthritis. ( Ahmed, U; Rabbani, N; Thornalley, PJ, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahmed, U1
Thornalley, PJ1
Rabbani, N1
Verzijl, N1
DeGroot, J1
Ben, ZC1
Brau-Benjamin, O1
Maroudas, A1
Bank, RA1
Mizrahi, J1
Schalkwijk, CG1
Thorpe, SR1
Baynes, JW1
Bijlsma, JW1
Lafeber, FP1
TeKoppele, JM1

Reviews

1 review available for pyruvaldehyde and Osteoarthritis

ArticleYear
Possible role of methylglyoxal and glyoxalase in arthritis.
    Biochemical Society transactions, 2014, Volume: 42, Issue:2

    Topics: Animals; Arthritis, Rheumatoid; Humans; Inflammation; Lactoylglutathione Lyase; Osteoarthritis; Pyru

2014

Other Studies

1 other study available for pyruvaldehyde and Osteoarthritis

ArticleYear
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:1

    Topics: Adult; Aging; Arginine; Cartilage, Articular; Collagen; Cross-Linking Reagents; Glycation End Produc

2002