pyruvaldehyde has been researched along with Necrosis in 8 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These results collectively suggest that the treatment dosage of MG and glucose could determine the mode of cell death (apoptosis vs." | 1.35 | Methylglyoxal and high glucose co-treatment induces apoptosis or necrosis in human umbilical vein endothelial cells. ( Chan, WH; Wu, HJ, 2008) |
| " In this study, the changes in the cellular and extracellular concentrations of these alpha-oxoaldehydes were investigated in murine P388D1 macrophages during necrotic cell death induced by median toxic concentrations of hydrogen peroxide and 1-chloro-2,4-dinitrobenzene (CDNB)." | 1.30 | Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity. ( Abordo, EA; Minhas, HS; Thornalley, PJ, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, D | 1 |
| Fiske, BP | 1 |
| Birsoy, K | 1 |
| Freinkman, E | 1 |
| Kami, K | 1 |
| Possemato, RL | 1 |
| Chudnovsky, Y | 1 |
| Pacold, ME | 1 |
| Chen, WW | 1 |
| Cantor, JR | 1 |
| Shelton, LM | 1 |
| Gui, DY | 1 |
| Kwon, M | 1 |
| Ramkissoon, SH | 1 |
| Ligon, KL | 1 |
| Kang, SW | 1 |
| Snuderl, M | 1 |
| Vander Heiden, MG | 1 |
| Sabatini, DM | 1 |
| Paul-Samojedny, M | 1 |
| Łasut, B | 1 |
| Pudełko, A | 1 |
| Fila-Daniłow, A | 1 |
| Kowalczyk, M | 1 |
| Suchanek-Raif, R | 1 |
| Zieliński, M | 1 |
| Borkowska, P | 1 |
| Kowalski, J | 1 |
| Lund, T | 1 |
| Svindland, A | 1 |
| Pepaj, M | 1 |
| Jensen, AB | 1 |
| Berg, JP | 1 |
| Kilhovd, B | 1 |
| Hanssen, KF | 1 |
| Maeta, K | 1 |
| Mori, K | 1 |
| Takatsume, Y | 1 |
| Izawa, S | 1 |
| Inoue, Y | 1 |
| Jan, CR | 1 |
| Chen, CH | 1 |
| Wang, SC | 1 |
| Kuo, SY | 1 |
| Chan, WH | 1 |
| Wu, HJ | 1 |
| Nakayama, M | 1 |
| Nakayama, K | 1 |
| Zhu, WJ | 1 |
| Shirota, Y | 1 |
| Terawaki, H | 1 |
| Sato, T | 1 |
| Kohno, M | 1 |
| Ito, S | 1 |
| Abordo, EA | 1 |
| Minhas, HS | 1 |
| Thornalley, PJ | 1 |
8 other studies available for pyruvaldehyde and Necrosis
| Article | Year |
|---|---|
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Topics: Acetone; Animals; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glioblasto | 2015 |
Methylglyoxal (MGO) inhibits proliferation and induces cell death of human glioblastoma multiforme T98G and U87MG cells.
Topics: Apoptosis; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Necro | 2016 |
Fibrin(ogen) may be an important target for methylglyoxal-derived AGE modification in elastic arteries of humans.
Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Aorta; Blotting, Western; Carotid Artery, Common; Case | 2011 |
Diagnosis of cell death induced by methylglyoxal, a metabolite derived from glycolysis, in Saccharomyces cerevisiae.
Topics: Cell Death; Glycolysis; In Situ Nick-End Labeling; Necrosis; Pyruvaldehyde; Reactive Oxygen Species; | 2005 |
Effect of methylglyoxal on intracellular calcium levels and viability in renal tubular cells.
Topics: Animals; Apoptosis; Calcium; Calcium Signaling; Cell Proliferation; Cell Survival; Cells, Cultured; | 2005 |
Methylglyoxal and high glucose co-treatment induces apoptosis or necrosis in human umbilical vein endothelial cells.
Topics: Apoptosis; Caspases; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; Endothel | 2008 |
Polymorphonuclear leukocyte injury by methylglyoxal and hydrogen peroxide: a possible pathological role for enhanced oxidative stress in chronic kidney disease.
Topics: Apoptosis; Cell Survival; Drug Synergism; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniq | 2008 |
Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity.
Topics: Animals; Cell Line; Cell Survival; Deoxyglucose; Dinitrochlorobenzene; Glutathione; Glyoxal; Guanidi | 1999 |